IMP

Process View

Mus musculus

1 genes annotated in mouse

regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.999
Gli3	GLI-Kruppel family member GLI3	0.999
Fgfr2	fibroblast growth factor receptor 2	0.997
Pax3	paired box gene 3	0.992
Fgf8	fibroblast growth factor 8	0.966
Isl1	ISL1 transcription factor, LIM/homeodomain	0.960
Tcfap2a	transcription factor AP-2, alpha	0.935
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.919
Bmp4	bone morphogenetic protein 4	0.895
Chd7	chromodomain helicase DNA binding protein 7	0.880
Otx2	orthodenticle homolog 2 (Drosophila)	0.878
Eya1	eyes absent 1 homolog (Drosophila)	0.872
Pax6	paired box gene 6	0.832
Pitx2	paired-like homeodomain transcription factor 2	0.796
Meox2	mesenchyme homeobox 2	0.789
Msx1	homeobox, msh-like 1	0.719
Foxc1	forkhead box C1	0.718
Hand1	heart and neural crest derivatives expressed transcript 1	0.662
Prrx1	paired related homeobox 1	0.620
Tgfb2	transforming growth factor, beta 2	0.602
Fgf10	fibroblast growth factor 10	0.588
Pax2	paired box gene 2	0.536
Ednra	endothelin receptor type A	0.521
Foxc2	forkhead box C2	0.448
Gli2	GLI-Kruppel family member GLI2	0.443
Hand2	heart and neural crest derivatives expressed transcript 2	0.429
She	src homology 2 domain-containing transforming protein E	0.424
Smo	smoothened homolog (Drosophila)	0.408
Gbx2	gastrulation brain homeobox 2	0.379
Tbx1	T-box 1	0.337
Fgfr1	fibroblast growth factor receptor 1	0.332
Nog	noggin	0.323
Nf1	neurofibromatosis 1	0.314
Foxg1	forkhead box G1	0.301
Bmp7	bone morphogenetic protein 7	0.292
Fgfr3	fibroblast growth factor receptor 3	0.288
Alx4	aristaless-like homeobox 4	0.279
Dlx5	distal-less homeobox 5	0.262
Efnb2	ephrin B2	0.250
Emx1	empty spiracles homolog 1 (Drosophila)	0.241
Rarg	retinoic acid receptor, gamma	0.226
Sox11	SRY-box containing gene 11	0.223	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.214
Hes1	hairy and enhancer of split 1 (Drosophila)	0.212
Gdnf	glial cell line derived neurotrophic factor	0.205
Rarb	retinoic acid receptor, beta	0.200
Ptch1	patched homolog 1	0.199
Col2a1	collagen, type II, alpha 1	0.187
Gata4	GATA binding protein 4	0.187
Sall4	sal-like 4 (Drosophila)	0.177
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.176
Sox2	SRY-box containing gene 2	0.167	Mouse
Pou5f1	POU domain, class 5, transcription factor 1	0.159
Pitx1	paired-like homeodomain transcription factor 1	0.158
Ntf3	neurotrophin 3	0.155
Jag1	jagged 1	0.151
Fgf3	fibroblast growth factor 3	0.149
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.146
Vangl2	vang-like 2 (van gogh, Drosophila)	0.146
Zeb1	zinc finger E-box binding homeobox 1	0.131
Prrx2	paired related homeobox 2	0.128
Emx2	empty spiracles homolog 2 (Drosophila)	0.121
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.115
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.115
Hes5	hairy and enhancer of split 5 (Drosophila)	0.113
Sall3	sal-like 3 (Drosophila)	0.112
Otx1	orthodenticle homolog 1 (Drosophila)	0.100
Msx2	homeobox, msh-like 2	0.095
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.092
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.090
Alx3	aristaless-like homeobox 3	0.089
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.081
Lef1	lymphoid enhancer binding factor 1	0.080
Atoh7	atonal homolog 7 (Drosophila)	0.077
Ret	ret proto-oncogene	0.076
Hoxa1	homeobox A1	0.076
Pbx1	pre B-cell leukemia transcription factor 1	0.073
Sox9	SRY-box containing gene 9	0.072	Mouse
Trp63	transformation related protein 63	0.066
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.065
Lmx1b	LIM homeobox transcription factor 1 beta	0.064
Rara	retinoic acid receptor, alpha	0.059
Tcfap2c	transcription factor AP-2, gamma	0.057
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.056
Ctnnb1	catenin (cadherin associated protein), beta 1	0.055
Dlx1	distal-less homeobox 1	0.053
Bmper	BMP-binding endothelial regulator	0.053
Hoxa3	homeobox A3	0.052
Chrd	chordin	0.051
Alx1	ALX homeobox 1	0.049
Hoxd13	homeobox D13	0.048
Tcf15	transcription factor 15	0.046
Gsc	goosecoid homeobox	0.046
Hoxa2	homeobox A2	0.046
Ptprb	protein tyrosine phosphatase, receptor type, B	0.046
Fgf4	fibroblast growth factor 4	0.045
Nanog	Nanog homeobox	0.043
Tbx3	T-box 3	0.042
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.042
Sox4	SRY-box containing gene 4	0.042	Mouse
Pthlh	parathyroid hormone-like peptide	0.041
Pou3f1	POU domain, class 3, transcription factor 1	0.038
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.037
Pax9	paired box gene 9	0.037
Rxra	retinoid X receptor alpha	0.036
Tbx2	T-box 2	0.035
Pou3f3	POU domain, class 3, transcription factor 3	0.034
Tbx15	T-box 15	0.034
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.033
Zic3	zinc finger protein of the cerebellum 3	0.033
Insm1	insulinoma-associated 1	0.033
Sox3	SRY-box containing gene 3	0.033	Mouse
Vegfa	vascular endothelial growth factor A	0.032
Lrp2	low density lipoprotein receptor-related protein 2	0.032
Hesx1	homeobox gene expressed in ES cells	0.032
Runx2	runt related transcription factor 2	0.032
Ephb2	Eph receptor B2	0.032
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.031
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.031
En2	engrailed 2	0.030
Aplnr	apelin receptor	0.030
Wnt3a	wingless-related MMTV integration site 3A	0.029
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.028
Lhx3	LIM homeobox protein 3	0.028
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.027
Efna2	ephrin A2	0.026
Gata3	GATA binding protein 3	0.025
Sox18	SRY-box containing gene 18	0.025	Mouse
Cldn5	claudin 5	0.025
Arx	aristaless related homeobox	0.025
Nodal	nodal	0.025
Eda	ectodysplasin-A	0.024
Btbd17	BTB (POZ) domain containing 17	0.024
Twist2	twist homolog 2 (Drosophila)	0.023
Bmp2	bone morphogenetic protein 2	0.023
Nkx6-1	NK6 homeobox 1	0.023
Neurod1	neurogenic differentiation 1	0.022
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.022
Lhx1	LIM homeobox protein 1	0.022
Hoxa5	homeobox A5	0.022
Trp53	transformation related protein 53	0.020
Fgfrl1	fibroblast growth factor receptor-like 1	0.020
Ebf3	early B-cell factor 3	0.020
Hoxb13	homeobox B13	0.020
Lhx5	LIM homeobox protein 5	0.020
Neurog2	neurogenin 2	0.020
Bdnf	brain derived neurotrophic factor	0.019
Smad6	MAD homolog 6 (Drosophila)	0.019
Foxf2	forkhead box F2	0.019
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.019
Sfn	stratifin	0.018
Ednrb	endothelin receptor type B	0.018
Bcl6b	B-cell CLL/lymphoma 6, member B	0.018
En1	engrailed 1	0.018
Notch3	Notch gene homolog 3 (Drosophila)	0.018
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.018
Dlx2	distal-less homeobox 2	0.018
Gas1	growth arrest specific 1	0.018
Fzd4	frizzled homolog 4 (Drosophila)	0.018
Gata6	GATA binding protein 6	0.017
Tead4	TEA domain family member 4	0.017
Mesp1	mesoderm posterior 1	0.017
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.016
H1fx	H1 histone family, member X	0.016
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.016
Krt17	keratin 17	0.016
Ihh	Indian hedgehog	0.016
Wnt6	wingless-related MMTV integration site 6	0.016
Esrrb	estrogen related receptor, beta	0.016
Wnt5a	wingless-related MMTV integration site 5A	0.015
Cxcl12	chemokine (C-X-C motif) ligand 12	0.015
Bmp5	bone morphogenetic protein 5	0.015
Pou4f2	POU domain, class 4, transcription factor 2	0.015
Nos3	nitric oxide synthase 3, endothelial cell	0.015
Hmx3	H6 homeobox 3	0.014
Epha4	Eph receptor A4	0.014
Zic2	zinc finger protein of the cerebellum 2	0.014
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.014
Sall1	sal-like 1 (Drosophila)	0.014
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.014
Hoxd3	homeobox D3	0.014
Nkx3-2	NK3 homeobox 2	0.014
Tbx10	T-box 10	0.013
Hoxb6	homeobox B6	0.013
Gh	growth hormone	0.013
Col1a1	collagen, type I, alpha 1	0.013
Nptx2	neuronal pentraxin 2	0.013
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.013
Meox1	mesenchyme homeobox 1	0.013
Pax1	paired box gene 1	0.013
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.013
Hoxc4	homeobox C4	0.013
Kcnk2	potassium channel, subfamily K, member 2	0.013
Pou3f4	POU domain, class 3, transcription factor 4	0.013
Ptk7	PTK7 protein tyrosine kinase 7	0.013
Foxd2	forkhead box D2	0.013
Hoxa13	homeobox A13	0.013
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.013
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.012
Apln	apelin	0.012
Uncx	UNC homeobox	0.012
Col11a1	collagen, type XI, alpha 1	0.012
Cbln1	cerebellin 1 precursor protein	0.012
Foxd1	forkhead box D1	0.012
Kdr	kinase insert domain protein receptor	0.012
Tpbg	trophoblast glycoprotein	0.012
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.012
Emid2	EMI domain containing 2	0.012
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.012
Wnt7b	wingless-related MMTV integration site 7B	0.012
Acvr1	activin A receptor, type 1	0.012
Cabp7	calcium binding protein 7	0.012
Fgf18	fibroblast growth factor 18	0.012
Dlk1	delta-like 1 homolog (Drosophila)	0.012
Nrtn	neurturin	0.012
Rcor2	REST corepressor 2	0.012
Lgals7	lectin, galactose binding, soluble 7	0.012
Sry	sex determining region of Chr Y	0.011	Mouse
Wnt4	wingless-related MMTV integration site 4	0.011
Sfrp2	secreted frizzled-related protein 2	0.011
Col9a1	collagen, type IX, alpha 1	0.011
Tcf21	transcription factor 21	0.011
Tcfcp2l1	transcription factor CP2-like 1	0.011
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.011
Hoxd11	homeobox D11	0.011
Edar	ectodysplasin-A receptor	0.011
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.011
Oc90	otoconin 90	0.011
Onecut1	one cut domain, family member 1	0.011
Edn3	endothelin 3	0.011
Lhx6	LIM homeobox protein 6	0.011
Olig2	oligodendrocyte transcription factor 2	0.011
Lmx1a	LIM homeobox transcription factor 1 alpha	0.010
Gja4	gap junction protein, alpha 4	0.010
Pcdh12	protocadherin 12	0.010
Hoxb3	homeobox B3	0.010
Col22a1	collagen, type XXII, alpha 1	0.010
Foxi3	forkhead box I3	0.010
Phox2b	paired-like homeobox 2b	0.010
Gli1	GLI-Kruppel family member GLI1	0.010
Hhex	hematopoietically expressed homeobox	0.010