IMP

Process View

Mus musculus

10 genes annotated in mouse

Multi-species View

negative regulation of astrocyte differentiation

GO:0048712

Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of astrocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of astrocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	1.000	Mouse
Shh	sonic hedgehog	1.000
Sox9	SRY-box containing gene 9	0.998
Foxc1	forkhead box C1	0.998
Fgfr1	fibroblast growth factor receptor 1	0.997	Mouse
Gli3	GLI-Kruppel family member GLI3	0.996
Pax3	paired box gene 3	0.995
Prrx1	paired related homeobox 1	0.995
Otx2	orthodenticle homolog 2 (Drosophila)	0.991
Bmp4	bone morphogenetic protein 4	0.991
Eya1	eyes absent 1 homolog (Drosophila)	0.989
Tcfap2a	transcription factor AP-2, alpha	0.980
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.978
Emx1	empty spiracles homolog 1 (Drosophila)	0.976
Pax6	paired box gene 6	0.973
Foxc2	forkhead box C2	0.972
Isl1	ISL1 transcription factor, LIM/homeodomain	0.969
Smo	smoothened homolog (Drosophila)	0.965
Tbx1	T-box 1	0.962
Fgf8	fibroblast growth factor 8	0.950
Ctnnb1	catenin (cadherin associated protein), beta 1	0.945
Foxg1	forkhead box G1	0.941
Sox2	SRY-box containing gene 2	0.927
Id3	inhibitor of DNA binding 3	0.924	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.913
Emx2	empty spiracles homolog 2 (Drosophila)	0.906
Msx1	homeobox, msh-like 1	0.903
Tgfb2	transforming growth factor, beta 2	0.883
Chrd	chordin	0.807
Dlx5	distal-less homeobox 5	0.806
Meox2	mesenchyme homeobox 2	0.790
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.785
Id1	inhibitor of DNA binding 1	0.781	Mouse
Ptch1	patched homolog 1	0.763
Hes1	hairy and enhancer of split 1 (Drosophila)	0.762	Mouse
Gsc	goosecoid homeobox	0.749
Vangl2	vang-like 2 (van gogh, Drosophila)	0.705
Chd7	chromodomain helicase DNA binding protein 7	0.697
Acvr1	activin A receptor, type 1	0.690
Rarb	retinoic acid receptor, beta	0.682
Gli2	GLI-Kruppel family member GLI2	0.668
Psen1	presenilin 1	0.647
Pbx1	pre B-cell leukemia transcription factor 1	0.639
Bmp7	bone morphogenetic protein 7	0.635
Pitx2	paired-like homeodomain transcription factor 2	0.593
Nog	noggin	0.589
Notch1	Notch gene homolog 1 (Drosophila)	0.562
Msx2	homeobox, msh-like 2	0.546
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.529
Efnb2	ephrin B2	0.517
Zeb1	zinc finger E-box binding homeobox 1	0.497
Hand1	heart and neural crest derivatives expressed transcript 1	0.475
Ednra	endothelin receptor type A	0.474	Mouse
Gbx2	gastrulation brain homeobox 2	0.458
Sox11	SRY-box containing gene 11	0.445
Prrx2	paired related homeobox 2	0.418
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.399
Ret	ret proto-oncogene	0.341
Vegfa	vascular endothelial growth factor A	0.304
Rarg	retinoic acid receptor, gamma	0.301
Rara	retinoic acid receptor, alpha	0.289
Rb1	retinoblastoma 1	0.287
Pax2	paired box gene 2	0.285
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.271
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.248
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.244
Jag1	jagged 1	0.235
Dlx6	distal-less homeobox 6	0.231
Dcx	doublecortin	0.230
Hoxa1	homeobox A1	0.204
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.194
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.192
Fgf10	fibroblast growth factor 10	0.190
Sox4	SRY-box containing gene 4	0.160
Otx1	orthodenticle homolog 1 (Drosophila)	0.145
Ntf3	neurotrophin 3	0.142
Tcf3	transcription factor 3	0.142
Bdnf	brain derived neurotrophic factor	0.140
Reln	reelin	0.139
Hoxa2	homeobox A2	0.127
Ece1	endothelin converting enzyme 1	0.126
Foxi3	forkhead box I3	0.117
Foxa2	forkhead box A2	0.108
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.107
Dlx2	distal-less homeobox 2	0.105
Fgfr3	fibroblast growth factor receptor 3	0.102
Pax1	paired box gene 1	0.098
Tcf21	transcription factor 21	0.095
Wnt3a	wingless-related MMTV integration site 3A	0.095
Alx4	aristaless-like homeobox 4	0.091
Lmx1b	LIM homeobox transcription factor 1 beta	0.089
Bmp2	bone morphogenetic protein 2	0.087
Mesp1	mesoderm posterior 1	0.086
Dll1	delta-like 1 (Drosophila)	0.083
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.083
Tcf4	transcription factor 4	0.079
Lrp6	low density lipoprotein receptor-related protein 6	0.078
Bmp5	bone morphogenetic protein 5	0.075
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.072
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.072
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.071
Apaf1	apoptotic peptidase activating factor 1	0.071
Trp53	transformation related protein 53	0.068
Sox10	SRY-box containing gene 10	0.068
Neurod1	neurogenic differentiation 1	0.066
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.065
Hoxa3	homeobox A3	0.057
Alx1	ALX homeobox 1	0.054
Lef1	lymphoid enhancer binding factor 1	0.053
Col2a1	collagen, type II, alpha 1	0.051
Dlx1	distal-less homeobox 1	0.049
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.048
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.048
Nf1	neurofibromatosis 1	0.046
Runx2	runt related transcription factor 2	0.046
Notch2	Notch gene homolog 2 (Drosophila)	0.045
Tgfbr2	transforming growth factor, beta receptor II	0.045
Neurog2	neurogenin 2	0.044
Egfr	epidermal growth factor receptor	0.043
Smad6	MAD homolog 6 (Drosophila)	0.042
Sox1	SRY-box containing gene 1	0.041
Braf	Braf transforming gene	0.040
Max	Max protein	0.040
Hes5	hairy and enhancer of split 5 (Drosophila)	0.038
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.038
Hesx1	homeobox gene expressed in ES cells	0.034
Nkx3-2	NK3 homeobox 2	0.034
Tbx3	T-box 3	0.033
Phox2b	paired-like homeobox 2b	0.032
Uncx	UNC homeobox	0.032
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.032
Nrg1	neuregulin 1	0.031
Mn1	meningioma 1	0.031
Hoxd11	homeobox D11	0.031
Pten	phosphatase and tensin homolog	0.030
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.029
Pax9	paired box gene 9	0.028
Nrarp	Notch-regulated ankyrin repeat protein	0.026
Thbs1	thrombospondin 1	0.024
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.024
Wnt1	wingless-related MMTV integration site 1	0.023
Tbx15	T-box 15	0.023
Lhx5	LIM homeobox protein 5	0.023
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.023
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.023
Tlx3	T-cell leukemia, homeobox 3	0.023
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.022
Rdh10	retinol dehydrogenase 10 (all-trans)	0.021
Fzd1	frizzled homolog 1 (Drosophila)	0.021
Pofut1	protein O-fucosyltransferase 1	0.021
Rxra	retinoid X receptor alpha	0.021
Gas1	growth arrest specific 1	0.021
Sall3	sal-like 3 (Drosophila)	0.021
Kitl	kit ligand	0.021
Lhx3	LIM homeobox protein 3	0.020
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.020
Hmx1	H6 homeobox 1	0.020
Pcp2	Purkinje cell protein 2 (L7)	0.020
Olig2	oligodendrocyte transcription factor 2	0.020
Hif1a	hypoxia inducible factor 1, alpha subunit	0.020
En1	engrailed 1	0.020
Ptk7	PTK7 protein tyrosine kinase 7	0.020
Gpc3	glypican 3	0.018
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.018
Hoxd3	homeobox D3	0.018
En2	engrailed 2	0.018
Ptf1a	pancreas specific transcription factor, 1a	0.018
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.018
Pou3f3	POU domain, class 3, transcription factor 3	0.018
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.018
Hoxa5	homeobox A5	0.017
Fgfrl1	fibroblast growth factor receptor-like 1	0.017
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.017
Mitf	microphthalmia-associated transcription factor	0.017
Sh3gl2	SH3-domain GRB2-like 2	0.017
Tshz1	teashirt zinc finger family member 1	0.016
Fgf9	fibroblast growth factor 9	0.016
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.015
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.015
Alx3	aristaless-like homeobox 3	0.015
Efna2	ephrin A2	0.015
Mtap1b	microtubule-associated protein 1B	0.015
Dclk1	doublecortin-like kinase 1	0.014
Mesp2	mesoderm posterior 2	0.014
Nkx2-1	NK2 homeobox 1	0.014
Olig1	oligodendrocyte transcription factor 1	0.014
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.014
Neurog1	neurogenin 1	0.014
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.014
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.014
Gata3	GATA binding protein 3	0.014
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.014
Hoxa13	homeobox A13	0.013
Trp63	transformation related protein 63	0.013
Ntsr1	neurotensin receptor 1	0.013
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.013
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.013
Bmper	BMP-binding endothelial regulator	0.013
Spnb3	spectrin beta 3	0.013
Nostrin	nitric oxide synthase trafficker	0.013
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.013
Pou3f2	POU domain, class 3, transcription factor 2	0.013
Pou3f4	POU domain, class 3, transcription factor 4	0.012
Zic4	zinc finger protein of the cerebellum 4	0.012
Ephb2	Eph receptor B2	0.012
App	amyloid beta (A4) precursor protein	0.012
Phox2a	paired-like homeobox 2a	0.012
Sva	seminal vesicle antigen	0.012
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.012
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.012
Msi1	Musashi homolog 1(Drosophila)	0.012
Pth1r	parathyroid hormone 1 receptor	0.012
Tcfap2b	transcription factor AP-2 beta	0.012
Foxa1	forkhead box A1	0.012
Kit	kit oncogene	0.011
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
Wnt5a	wingless-related MMTV integration site 5A	0.011
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.011
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.011
Mycs	myc-like oncogene, s-myc protein	0.011	Mouse
Pthlh	parathyroid hormone-like peptide	0.011
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.011	Mouse
Kif3a	kinesin family member 3A	0.010
Mmp24	matrix metallopeptidase 24	0.010
Insm1	insulinoma-associated 1	0.010
Fgfr4	fibroblast growth factor receptor 4	0.010	Mouse
Efna4	ephrin A4	0.010
Ccnd1	cyclin D1	0.010
Apc	adenomatosis polyposis coli	0.010
Galr3	galanin receptor 3	0.010
Trp73	transformation related protein 73	0.010