IMP
Process View
positive regulation of lens epithelial cell proliferation
Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of lens epithelial cell proliferation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | ||
| Pax3 | paired box gene 3 | 0.999 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.998 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.988 | ||
| Meox2 | mesenchyme homeobox 2 | 0.980 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.972 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.970 | ||
| Fgf8 | fibroblast growth factor 8 | 0.967 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.965 | ||
| Pax6 | paired box gene 6 | 0.964 | ||
| Foxc1 | forkhead box C1 | 0.946 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.937 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.899 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.873 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.852 | ||
| Fgf10 | fibroblast growth factor 10 | 0.850 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.836 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.820 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.808 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.782 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.752 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.750 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.741 | ||
| Prrx1 | paired related homeobox 1 | 0.736 | ||
| Sox11 | SRY-box containing gene 11 | 0.734 | ||
| Msx1 | homeobox, msh-like 1 | 0.723 | ||
| Foxc2 | forkhead box C2 | 0.711 | ||
| Nf1 | neurofibromatosis 1 | 0.690 | ||
| Smo | smoothened homolog (Drosophila) | 0.641 | ||
| Pax2 | paired box gene 2 | 0.631 | ||
| Sox4 | SRY-box containing gene 4 | 0.606 | Mouse | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.593 | ||
| Rarb | retinoic acid receptor, beta | 0.575 | ||
| Nog | noggin | 0.573 | ||
| Alx4 | aristaless-like homeobox 4 | 0.553 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.526 | ||
| Ntf3 | neurotrophin 3 | 0.513 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.466 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.456 | ||
| Rb1 | retinoblastoma 1 | 0.446 | ||
| Vegfa | vascular endothelial growth factor A | 0.417 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.403 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.373 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.365 | ||
| Jag1 | jagged 1 | 0.349 | ||
| Emcn | endomucin | 0.329 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.317 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.312 | ||
| Foxg1 | forkhead box G1 | 0.312 | ||
| Prrx2 | paired related homeobox 2 | 0.309 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.303 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.302 | ||
| Efnb2 | ephrin B2 | 0.294 | ||
| Tbx1 | T-box 1 | 0.289 | ||
| Gata4 | GATA binding protein 4 | 0.282 | ||
| She | src homology 2 domain-containing transforming protein E | 0.274 | ||
| Ret | ret proto-oncogene | 0.266 | ||
| Trp53 | transformation related protein 53 | 0.266 | ||
| Fgf3 | fibroblast growth factor 3 | 0.259 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.258 | ||
| Ptch1 | patched homolog 1 | 0.244 | ||
| Col2a1 | collagen, type II, alpha 1 | 0.241 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.227 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.223 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.219 | ||
| Dlx5 | distal-less homeobox 5 | 0.217 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.217 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.197 | ||
| Pten | phosphatase and tensin homolog | 0.197 | ||
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.187 | ||
| Cldn5 | claudin 5 | 0.187 | ||
| Rarg | retinoic acid receptor, gamma | 0.184 | ||
| Trp63 | transformation related protein 63 | 0.167 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.161 | ||
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.158 | ||
| Alx3 | aristaless-like homeobox 3 | 0.150 | ||
| Kit | kit oncogene | 0.148 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.145 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.143 | ||
| Sall3 | sal-like 3 (Drosophila) | 0.138 | ||
| Lhx3 | LIM homeobox protein 3 | 0.135 | ||
| Atoh7 | atonal homolog 7 (Drosophila) | 0.134 | ||
| Sox9 | SRY-box containing gene 9 | 0.133 | Mouse | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.124 | ||
| Hoxa1 | homeobox A1 | 0.123 | ||
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.123 | ||
| Ednrb | endothelin receptor type B | 0.115 | ||
| Alx1 | ALX homeobox 1 | 0.109 | ||
| Kdr | kinase insert domain protein receptor | 0.107 | ||
| Sox17 | SRY-box containing gene 17 | 0.100 | Mouse | |
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.099 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.096 | ||
| Rara | retinoic acid receptor, alpha | 0.093 | ||
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.092 | ||
| Pthlh | parathyroid hormone-like peptide | 0.089 | ||
| Rxra | retinoid X receptor alpha | 0.086 | ||
| Icam2 | intercellular adhesion molecule 2 | 0.083 | ||
| Msx2 | homeobox, msh-like 2 | 0.081 | ||
| Kitl | kit ligand | 0.080 | ||
| Chrd | chordin | 0.078 | ||
| Hoxa2 | homeobox A2 | 0.070 | ||
| Tbx15 | T-box 15 | 0.069 | ||
| Ednra | endothelin receptor type A | 0.069 | ||
| Foxh1 | forkhead box H1 | 0.069 | ||
| Bmper | BMP-binding endothelial regulator | 0.068 | ||
| Apc | adenomatosis polyposis coli | 0.068 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.068 | ||
| Tcfap2c | transcription factor AP-2, gamma | 0.066 | ||
| Fgf4 | fibroblast growth factor 4 | 0.063 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.063 | ||
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.063 | ||
| Sox18 | SRY-box containing gene 18 | 0.063 | Mouse | |
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.063 | ||
| Tcf15 | transcription factor 15 | 0.062 | ||
| Sox2 | SRY-box containing gene 2 | 0.061 | Mouse | |
| Ushbp1 | Usher syndrome 1C binding protein 1 | 0.060 | ||
| Esam | endothelial cell-specific adhesion molecule | 0.060 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.060 | ||
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.060 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.058 | ||
| Nanog | Nanog homeobox | 0.058 | ||
| Insm1 | insulinoma-associated 1 | 0.058 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.057 | ||
| Aplnr | apelin receptor | 0.056 | ||
| Hoxa5 | homeobox A5 | 0.055 | ||
| Nodal | nodal | 0.055 | ||
| Tbx3 | T-box 3 | 0.051 | ||
| Hesx1 | homeobox gene expressed in ES cells | 0.051 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.051 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.051 | ||
| Gata3 | GATA binding protein 3 | 0.050 | ||
| Meox1 | mesenchyme homeobox 1 | 0.049 | ||
| Zic3 | zinc finger protein of the cerebellum 3 | 0.048 | ||
| Gsc | goosecoid homeobox | 0.046 | ||
| Wnt3a | wingless-related MMTV integration site 3A | 0.046 | ||
| Rasip1 | Ras interacting protein 1 | 0.045 | ||
| Cilp2 | cartilage intermediate layer protein 2 | 0.042 | ||
| Tek | endothelial-specific receptor tyrosine kinase | 0.042 | ||
| Runx2 | runt related transcription factor 2 | 0.041 | ||
| Hoxd13 | homeobox D13 | 0.040 | ||
| Gas1 | growth arrest specific 1 | 0.039 | ||
| Dlx1 | distal-less homeobox 1 | 0.039 | ||
| Nkx6-1 | NK6 homeobox 1 | 0.038 | ||
| Pax9 | paired box gene 9 | 0.037 | ||
| Krt17 | keratin 17 | 0.036 | ||
| Sfn | stratifin | 0.036 | ||
| Egfr | epidermal growth factor receptor | 0.035 | ||
| Cdh5 | cadherin 5 | 0.035 | ||
| Btbd17 | BTB (POZ) domain containing 17 | 0.035 | ||
| Hoxb13 | homeobox B13 | 0.034 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.034 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.033 | ||
| Hhex | hematopoietically expressed homeobox | 0.033 | ||
| Gja1 | gap junction protein, alpha 1 | 0.033 | ||
| Pou3f1 | POU domain, class 3, transcription factor 1 | 0.032 | ||
| Gja4 | gap junction protein, alpha 4 | 0.031 | ||
| Nkx2-2 | NK2 transcription factor related, locus 2 (Drosophila) | 0.031 | ||
| Eng | endoglin | 0.031 | ||
| Tbx2 | T-box 2 | 0.031 | ||
| Neurod1 | neurogenic differentiation 1 | 0.030 | ||
| Mcam | melanoma cell adhesion molecule | 0.030 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.030 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.030 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.029 | ||
| Hrh2 | histamine receptor H2 | 0.029 | ||
| Arx | aristaless related homeobox | 0.028 | ||
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.028 | ||
| Pax1 | paired box gene 1 | 0.026 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.026 | ||
| Sox7 | SRY-box containing gene 7 | 0.026 | Mouse | |
| En2 | engrailed 2 | 0.025 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.025 | ||
| Nkx2-1 | NK2 homeobox 1 | 0.025 | ||
| Mitf | microphthalmia-associated transcription factor | 0.025 | ||
| Eda | ectodysplasin-A | 0.024 | ||
| Robo4 | roundabout homolog 4 (Drosophila) | 0.024 | ||
| Mesp1 | mesoderm posterior 1 | 0.024 | ||
| Nfib | nuclear factor I/B | 0.024 | ||
| Tcf21 | transcription factor 21 | 0.023 | ||
| Xpo4 | exportin 4 | 0.023 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.022 | ||
| Ebf3 | early B-cell factor 3 | 0.022 | ||
| Dmrtb1 | DMRT-like family B with proline-rich C-terminal, 1 | 0.022 | ||
| Neurog2 | neurogenin 2 | 0.022 | ||
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.021 | ||
| Gata6 | GATA binding protein 6 | 0.021 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.020 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.020 | ||
| Fgd5 | FYVE, RhoGEF and PH domain containing 5 | 0.020 | ||
| Ldb2 | LIM domain binding 2 | 0.020 | ||
| Gh | growth hormone | 0.019 | ||
| Bdnf | brain derived neurotrophic factor | 0.019 | ||
| Efs | embryonal Fyn-associated substrate | 0.019 | ||
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.019 | ||
| Notch3 | Notch gene homolog 3 (Drosophila) | 0.019 | ||
| Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.019 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.019 | ||
| Lhx1 | LIM homeobox protein 1 | 0.019 | ||
| Ihh | Indian hedgehog | 0.018 | ||
| Ptrf | polymerase I and transcript release factor | 0.018 | ||
| Kcnk2 | potassium channel, subfamily K, member 2 | 0.018 | ||
| Hoxa3 | homeobox A3 | 0.018 | ||
| Tead4 | TEA domain family member 4 | 0.018 | ||
| Lhx5 | LIM homeobox protein 5 | 0.018 | ||
| Foxf1a | forkhead box F1a | 0.018 | ||
| Wnt6 | wingless-related MMTV integration site 6 | 0.018 | ||
| Nrtn | neurturin | 0.017 | ||
| Pou3f4 | POU domain, class 3, transcription factor 4 | 0.017 | ||
| Apln | apelin | 0.017 | ||
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.017 | ||
| Npr3 | natriuretic peptide receptor 3 | 0.017 | ||
| En1 | engrailed 1 | 0.017 | ||
| Alppl2 | alkaline phosphatase, placental-like 2 | 0.016 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.016 | ||
| Sall1 | sal-like 1 (Drosophila) | 0.016 | ||
| Nkx3-2 | NK3 homeobox 2 | 0.016 | ||
| Wt1 | Wilms tumor 1 homolog | 0.016 | ||
| Foxf2 | forkhead box F2 | 0.016 | ||
| Uncx | UNC homeobox | 0.016 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.016 | ||
| Foxd2 | forkhead box D2 | 0.016 | ||
| Hspa12b | heat shock protein 12B | 0.015 | ||
| Acan | aggrecan | 0.015 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.015 | ||
| Barx2 | BarH-like homeobox 2 | 0.015 | ||
| Mmrn2 | multimerin 2 | 0.015 | ||
| Cav1 | caveolin 1, caveolae protein | 0.015 | ||
| Acvr1 | activin A receptor, type 1 | 0.015 | ||
| Crhr2 | corticotropin releasing hormone receptor 2 | 0.015 | ||
| Trp73 | transformation related protein 73 | 0.015 | ||
| Olig2 | oligodendrocyte transcription factor 2 | 0.015 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.015 | ||
| Gli1 | GLI-Kruppel family member GLI1 | 0.014 | ||
| Foxa2 | forkhead box A2 | 0.014 | ||
| Edar | ectodysplasin-A receptor | 0.014 | ||
| Clic3 | chloride intracellular channel 3 | 0.014 | ||
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.014 | ||
| Lbx1 | ladybird homeobox homolog 1 (Drosophila) | 0.014 | ||
| Bmp6 | bone morphogenetic protein 6 | 0.014 | ||
| Epha4 | Eph receptor A4 | 0.014 | ||
| Ghrl | ghrelin | 0.013 | ||
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.013 | ||
| Wnt4 | wingless-related MMTV integration site 4 | 0.013 | ||
| 4922505E12Rik | RIKEN cDNA 4922505E12 gene | 0.013 | ||
| Gata2 | GATA binding protein 2 | 0.013 | ||
| Sfrp2 | secreted frizzled-related protein 2 | 0.013 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.013 | ||
| Foxj1 | forkhead box J1 | 0.013 | ||
| Wnt7b | wingless-related MMTV integration site 7B | 0.013 | ||
| Kl | klotho | 0.013 | ||
| Sox3 | SRY-box containing gene 3 | 0.013 | Mouse | |
| Npas1 | neuronal PAS domain protein 1 | 0.013 | ||
| Fgf18 | fibroblast growth factor 18 | 0.013 | ||
| Vstm2b | V-set and transmembrane domain containing 2B | 0.013 | ||
| Phox2b | paired-like homeobox 2b | 0.012 | ||
| Onecut1 | one cut domain, family member 1 | 0.012 | ||
| Mn1 | meningioma 1 | 0.012 | ||
| Fgf17 | fibroblast growth factor 17 | 0.012 | ||
| Edn3 | endothelin 3 | 0.012 | ||
| Pcdh12 | protocadherin 12 | 0.012 | ||
| Slurp1 | secreted Ly6/Plaur domain containing 1 | 0.012 | ||
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.012 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.012 | ||
| Gast | gastrin | 0.012 | ||
| Acvrl1 | activin A receptor, type II-like 1 | 0.012 | ||
| Lhx6 | LIM homeobox protein 6 | 0.012 | ||
| Sycn | syncollin | 0.012 | ||
| Hcrt | hypocretin | 0.012 | ||
| Ece1 | endothelin converting enzyme 1 | 0.012 | ||
| Esrrb | estrogen related receptor, beta | 0.012 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.012 | ||
| Dmrt1 | doublesex and mab-3 related transcription factor 1 | 0.012 | ||
| Myo6 | myosin VI | 0.012 | ||
| Clec3b | C-type lectin domain family 3, member b | 0.011 | ||
| Abcc9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 0.011 | ||
| Zic2 | zinc finger protein of the cerebellum 2 | 0.011 | ||
| Egfl7 | EGF-like domain 7 | 0.011 | ||
| Col4a2 | collagen, type IV, alpha 2 | 0.011 | ||
| Clcnka | chloride channel Ka | 0.011 | ||
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.011 | ||
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.011 | ||
| Dpep3 | dipeptidase 3 | 0.011 | ||
| Hoxa13 | homeobox A13 | 0.011 | ||
| Gpc3 | glypican 3 | 0.011 | ||
| Ramp2 | receptor (calcitonin) activity modifying protein 2 | 0.011 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.011 | ||
| Cdh8 | cadherin 8 | 0.011 | ||
| Galr2 | galanin receptor 2 | 0.011 | ||
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.011 | ||
| T | brachyury | 0.011 | ||
| H2-M9 | histocompatibility 2, M region locus 9 | 0.011 | ||
| Fuz | fuzzy homolog (Drosophila) | 0.011 | ||
| Krt16 | keratin 16 | 0.011 | ||
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.011 | ||
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.011 | ||
| Ankrd2 | ankyrin repeat domain 2 (stretch responsive muscle) | 0.011 | ||
| Slc22a12 | solute carrier family 22 (organic anion/cation transporter), member 12 | 0.011 | ||
| Barhl2 | BarH-like 2 (Drosophila) | 0.011 | ||
| Wnt3 | wingless-related MMTV integration site 3 | 0.011 | ||
| Sct | secretin | 0.011 | ||
| Ctgf | connective tissue growth factor | 0.010 | ||
| Crabp2 | cellular retinoic acid binding protein II | 0.010 | ||
| Gja5 | gap junction protein, alpha 5 | 0.010 | ||
| Tbx10 | T-box 10 | 0.010 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.010 | ||
| Fam171a1 | family with sequence similarity 171, member A1 | 0.010 | ||
| Efna2 | ephrin A2 | 0.010 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.010 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.010 | ||
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.010 | ||
| Ptch2 | patched homolog 2 | 0.010 | ||
| Fli1 | Friend leukemia integration 1 | 0.010 | ||
| Msx3 | homeobox, msh-like 3 | 0.010 | ||
| Zbtb16 | zinc finger and BTB domain containing 16 | 0.010 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.010 | ||
| Wnt7a | wingless-related MMTV integration site 7A | 0.010 |