IMP

Process View

Mus musculus

22 genes annotated in mouse

response to exogenous dsrna

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to exogenous dsrna"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to exogenous dsrna" (in gray)

Name	Description	Probability	Func Analog Organism
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.723
Myd88	myeloid differentiation primary response gene 88	0.681
Stat3	signal transducer and activator of transcription 3	0.291	Mouse
Lyz2	lysozyme 2	0.248
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.236
Tlr4	toll-like receptor 4	0.232
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.174
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.146
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.132
Traf6	TNF receptor-associated factor 6	0.127
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.106
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.102
Il1r1	interleukin 1 receptor, type I	0.071
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.065
Stat5b	signal transducer and activator of transcription 5B	0.063	Mouse
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.060
Cd44	CD44 antigen	0.049
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.048
Unc93b1	unc-93 homolog B1 (C. elegans)	0.044
Stat5a	signal transducer and activator of transcription 5A	0.044	Mouse
Casp1	caspase 1	0.041
Foxp3	forkhead box P3	0.038
Tnf	tumor necrosis factor	0.038	Zebrafish
Irgm1	immunity-related GTPase family M member 1	0.035
Il1b	interleukin 1 beta	0.033	Zebrafish
Ikzf1	IKAROS family zinc finger 1	0.033
Bcl3	B-cell leukemia/lymphoma 3	0.032	Mouse
Il4ra	interleukin 4 receptor, alpha	0.031
Socs3	suppressor of cytokine signaling 3	0.027
Trim21	tripartite motif-containing 21	0.027
Sfn	stratifin	0.026
Stat1	signal transducer and activator of transcription 1	0.026
Ticam1	toll-like receptor adaptor molecule 1	0.024
Tnip1	TNFAIP3 interacting protein 1	0.024
Ccl4	chemokine (C-C motif) ligand 4	0.024
Irak4	interleukin-1 receptor-associated kinase 4	0.024
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.023
Trp53	transformation related protein 53	0.023
Parp14	poly (ADP-ribose) polymerase family, member 14	0.023
Pycard	PYD and CARD domain containing	0.022
Nlrp3	NLR family, pyrin domain containing 3	0.021	Mouse
Sfpi1	SFFV proviral integration 1	0.021
Zfp36	zinc finger protein 36	0.021
Ikbkg	inhibitor of kappaB kinase gamma	0.021
Trim25	tripartite motif-containing 25	0.021
Fas	Fas (TNF receptor superfamily member 6)	0.020
Il6	interleukin 6	0.020
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.019
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.019
Igh	immunoglobulin heavy chain complex	0.019
Traf3	TNF receptor-associated factor 3	0.019
Irf7	interferon regulatory factor 7	0.018	Mouse
Rtp4	receptor transporter protein 4	0.018
Il10	interleukin 10	0.018
Casp8	caspase 8	0.017
Ifnar1	interferon (alpha and beta) receptor 1	0.017
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.017
Junb	Jun-B oncogene	0.016
Isg15	ISG15 ubiquitin-like modifier	0.016
Inadl	InaD-like (Drosophila)	0.016
Irak3	interleukin-1 receptor-associated kinase 3	0.015
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.014
Mx1	myxovirus (influenza virus) resistance 1	0.014
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.014
Cyld	cylindromatosis (turban tumor syndrome)	0.014
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.013	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.013
Cd79b	CD79B antigen	0.013
Cxcl2	chemokine (C-X-C motif) ligand 2	0.013
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.013
Lgals9	lectin, galactose binding, soluble 9	0.013
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.013
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.013
Ikbkb	inhibitor of kappaB kinase beta	0.013
Icos	inducible T-cell co-stimulator	0.012
BC006779	cDNA sequence BC006779	0.012
Rel	reticuloendotheliosis oncogene	0.012
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.012
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.012	Mouse
Itch	itchy, E3 ubiquitin protein ligase	0.011
Icam1	intercellular adhesion molecule 1	0.011
Pim1	proviral integration site 1	0.011
Cd40	CD40 antigen	0.011
Samd9l	sterile alpha motif domain containing 9-like	0.011
Atr	ataxia telangiectasia and Rad3 related	0.011
Zbp1	Z-DNA binding protein 1	0.011
Irf5	interferon regulatory factor 5	0.011	Mouse
Il6st	interleukin 6 signal transducer	0.010
Usp18	ubiquitin specific peptidase 18	0.010
Irf1	interferon regulatory factor 1	0.010	Mouse
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.010
Tifa	TRAF-interacting protein with forkhead-associated domain	0.010
Lepr	leptin receptor	0.010
Ptgs2	prostaglandin-endoperoxide synthase 2	0.010
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.010