IMP

Process View

Mus musculus

11 genes annotated in mouse

epithelial cell proliferation involved in prostate gland development

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "epithelial cell proliferation involved in prostate gland development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "epithelial cell proliferation involved in prostate gland development" (in gray)

Name	Description	Probability	Func Analog Organism
Ctnnb1	catenin (cadherin associated protein), beta 1	1.000
Fgfr2	fibroblast growth factor receptor 2	0.999
Gli3	GLI-Kruppel family member GLI3	0.991
Pten	phosphatase and tensin homolog	0.939
Trp53	transformation related protein 53	0.907
Meox2	mesenchyme homeobox 2	0.826
Bmp4	bone morphogenetic protein 4	0.751
Pax3	paired box gene 3	0.695
Rb1	retinoblastoma 1	0.647
Rxra	retinoid X receptor alpha	0.641
Gli2	GLI-Kruppel family member GLI2	0.631
Shh	sonic hedgehog	0.585
Prrx1	paired related homeobox 1	0.540
Col1a1	collagen, type I, alpha 1	0.415
Fgfr1	fibroblast growth factor receptor 1	0.408
Fgfr3	fibroblast growth factor receptor 3	0.381
Sox9	SRY-box containing gene 9	0.378
Runx2	runt related transcription factor 2	0.358
Psen1	presenilin 1	0.324
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.316
Col2a1	collagen, type II, alpha 1	0.306
Ptch1	patched homolog 1	0.305
Kit	kit oncogene	0.286
Hes1	hairy and enhancer of split 1 (Drosophila)	0.239
Msx1	homeobox, msh-like 1	0.237
Trp63	transformation related protein 63	0.217
Apc	adenomatosis polyposis coli	0.214
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.209
Pkd1	polycystic kidney disease 1 homolog	0.171
Alx4	aristaless-like homeobox 4	0.171
Nf1	neurofibromatosis 1	0.167
Ar	androgen receptor	0.161
Nos3	nitric oxide synthase 3, endothelial cell	0.160
Bmp2	bone morphogenetic protein 2	0.157
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.135
Dll1	delta-like 1 (Drosophila)	0.135
Dlx2	distal-less homeobox 2	0.132
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.125
She	src homology 2 domain-containing transforming protein E	0.118
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.110
Nog	noggin	0.109
Pbx1	pre B-cell leukemia transcription factor 1	0.096
Smo	smoothened homolog (Drosophila)	0.096
Zeb1	zinc finger E-box binding homeobox 1	0.093
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.090
Gata4	GATA binding protein 4	0.089
Hand1	heart and neural crest derivatives expressed transcript 1	0.086
Chd7	chromodomain helicase DNA binding protein 7	0.081
Smad3	MAD homolog 3 (Drosophila)	0.080
Sox11	SRY-box containing gene 11	0.073	Mouse
Dlx5	distal-less homeobox 5	0.071
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.070
Bmp7	bone morphogenetic protein 7	0.069
Egfl7	EGF-like domain 7	0.069
Hoxa10	homeobox A10	0.067
Cdh5	cadherin 5	0.065
Pthlh	parathyroid hormone-like peptide	0.065
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.063
Esr1	estrogen receptor 1 (alpha)	0.061
Ccnd1	cyclin D1	0.057
Msh2	mutS homolog 2 (E. coli)	0.056
Efnb2	ephrin B2	0.056
Sox18	SRY-box containing gene 18	0.056	Mouse
Lef1	lymphoid enhancer binding factor 1	0.054
Pax1	paired box gene 1	0.052
Ramp2	receptor (calcitonin) activity modifying protein 2	0.051
Alx3	aristaless-like homeobox 3	0.050
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.048
Gas1	growth arrest specific 1	0.047
Edar	ectodysplasin-A receptor	0.047
Notch3	Notch gene homolog 3 (Drosophila)	0.046	Mouse
Vangl2	vang-like 2 (van gogh, Drosophila)	0.046
Cldn5	claudin 5	0.046
Notch1	Notch gene homolog 1 (Drosophila)	0.045
Smad4	MAD homolog 4 (Drosophila)	0.045
Foxc1	forkhead box C1	0.044
Isl1	ISL1 transcription factor, LIM/homeodomain	0.043
Emx1	empty spiracles homolog 1 (Drosophila)	0.043
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.042
Fgf10	fibroblast growth factor 10	0.042
Pitx2	paired-like homeodomain transcription factor 2	0.042
Npr2	natriuretic peptide receptor 2	0.041
Otx2	orthodenticle homolog 2 (Drosophila)	0.040
Ahr	aryl-hydrocarbon receptor	0.039
Il6st	interleukin 6 signal transducer	0.038
Fgf8	fibroblast growth factor 8	0.038
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.036
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.034
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.033
Hoxa13	homeobox A13	0.032
Eng	endoglin	0.032
Hif1a	hypoxia inducible factor 1, alpha subunit	0.032
Pgr	progesterone receptor	0.031
Lrp6	low density lipoprotein receptor-related protein 6	0.031
Hnf4a	hepatic nuclear factor 4, alpha	0.030
Cdk4	cyclin-dependent kinase 4	0.030
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.027
Efnb1	ephrin B1	0.027
Wnt3a	wingless-related MMTV integration site 3A	0.026
Smad6	MAD homolog 6 (Drosophila)	0.025
Amhr2	anti-Mullerian hormone type 2 receptor	0.025
Sox7	SRY-box containing gene 7	0.024	Mouse
Tgfb2	transforming growth factor, beta 2	0.024
Emcn	endomucin	0.024
Drd2	dopamine receptor D2	0.023
Tbx2	T-box 2	0.023
Eda	ectodysplasin-A	0.023
Aplnr	apelin receptor	0.023
Foxa2	forkhead box A2	0.023
Loxl1	lysyl oxidase-like 1	0.023
Ptprb	protein tyrosine phosphatase, receptor type, B	0.023
Sox2	SRY-box containing gene 2	0.022	Mouse
Kdr	kinase insert domain protein receptor	0.022
Kitl	kit ligand	0.021
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.021
Hesx1	homeobox gene expressed in ES cells	0.020
Esr2	estrogen receptor 2 (beta)	0.020
Gja4	gap junction protein, alpha 4	0.020
Prlr	prolactin receptor	0.020
Dlx1	distal-less homeobox 1	0.020	Mouse
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.020
Psen2	presenilin 2	0.020
Sox17	SRY-box containing gene 17	0.020	Mouse
Pax6	paired box gene 6	0.020
Vhl	von Hippel-Lindau tumor suppressor	0.020
Satb2	special AT-rich sequence binding protein 2	0.020
Esam	endothelial cell-specific adhesion molecule	0.019
Zfp362	zinc finger protein 362	0.019
Gsk3b	glycogen synthase kinase 3 beta	0.019
Cxcl12	chemokine (C-X-C motif) ligand 12	0.019
Gsc	goosecoid homeobox	0.019
Tbx3	T-box 3	0.019
Atoh7	atonal homolog 7 (Drosophila)	0.018
Emid2	EMI domain containing 2	0.018
Alx1	ALX homeobox 1	0.017
Meox1	mesenchyme homeobox 1	0.017
Hoxa5	homeobox A5	0.017
Rasip1	Ras interacting protein 1	0.017
Ltbp4	latent transforming growth factor beta binding protein 4	0.017
Tsc1	tuberous sclerosis 1	0.017
Sox3	SRY-box containing gene 3	0.017	Mouse
Twist2	twist homolog 2 (Drosophila)	0.016
Pax9	paired box gene 9	0.016
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.016
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.016
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.016
Foxo3	forkhead box O3	0.016
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.015
Pitx1	paired-like homeodomain transcription factor 1	0.015
Tcfap2a	transcription factor AP-2, alpha	0.015
Apoe	apolipoprotein E	0.015
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.015
Bcl2	B-cell leukemia/lymphoma 2	0.015
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.015
Hhex	hematopoietically expressed homeobox	0.015
Sox4	SRY-box containing gene 4	0.015	Mouse
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.015
Wnt6	wingless-related MMTV integration site 6	0.015
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.014
Pax8	paired box gene 8	0.014
Wnt7a	wingless-related MMTV integration site 7A	0.014
Kl	klotho	0.014
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.014
Bnc1	basonuclin 1	0.014
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.014
Onecut1	one cut domain, family member 1	0.014
Fhl3	four and a half LIM domains 3	0.014
Stat3	signal transducer and activator of transcription 3	0.014
Sall3	sal-like 3 (Drosophila)	0.014
Hoxd13	homeobox D13	0.014
Mmp15	matrix metallopeptidase 15	0.013
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
Pdgfb	platelet derived growth factor, B polypeptide	0.013
Rarb	retinoic acid receptor, beta	0.013
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.013
Tcf15	transcription factor 15	0.013
Braf	Braf transforming gene	0.013
Sox13	SRY-box containing gene 13	0.013
Ephb4	Eph receptor B4	0.013
Gata3	GATA binding protein 3	0.012
Phldb1	pleckstrin homology-like domain, family B, member 1	0.012
Fgf4	fibroblast growth factor 4	0.012
Robo4	roundabout homolog 4 (Drosophila)	0.012
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.012
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.012	Mouse
Ldb2	LIM domain binding 2	0.012
Nes	nestin	0.012
Hoxa2	homeobox A2	0.012
Acan	aggrecan	0.012
Hand2	heart and neural crest derivatives expressed transcript 2	0.012
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.012
T	brachyury	0.012
Foxn1	forkhead box N1	0.012
Ski	ski sarcoma viral oncogene homolog (avian)	0.012
Mmrn2	multimerin 2	0.011
Ushbp1	Usher syndrome 1C binding protein 1	0.011
Adcy4	adenylate cyclase 4	0.011
Tcf21	transcription factor 21	0.011
Mks1	Meckel syndrome, type 1	0.011
Apln	apelin	0.011
Flt1	FMS-like tyrosine kinase 1	0.011
Foxd2	forkhead box D2	0.011
Kcnk2	potassium channel, subfamily K, member 2	0.011
Nop16	NOP16 nucleolar protein homolog (yeast)	0.011
Gcgr	glucagon receptor	0.011
Col22a1	collagen, type XXII, alpha 1	0.011
Gdnf	glial cell line derived neurotrophic factor	0.011
Tcfap2c	transcription factor AP-2, gamma	0.011
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.011
Yap1	yes-associated protein 1	0.011
Srsf2	serine/arginine-rich splicing factor 2	0.010
Hes5	hairy and enhancer of split 5 (Drosophila)	0.010
Zic3	zinc finger protein of the cerebellum 3	0.010
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.010
Irs3	insulin receptor substrate 3	0.010
Nynrin	NYN domain and retroviral integrase containing	0.010
Adra2b	adrenergic receptor, alpha 2b	0.010
Fzd8	frizzled homolog 8 (Drosophila)	0.010
Efs	embryonal Fyn-associated substrate	0.010
Kcnj8	potassium inwardly-rectifying channel, subfamily J, member 8	0.010
Pdx1	pancreatic and duodenal homeobox 1	0.010
Nf2	neurofibromatosis 2	0.010