IMP

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Mus musculus

7 genes annotated in mouse

adenylate cyclase activating dopamine receptor signaling pathway

The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "adenylate cyclase activating dopamine receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "adenylate cyclase activating dopamine receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Drd2	dopamine receptor D2	0.910	Mouse
Cckbr	cholecystokinin B receptor	0.894
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.872
Kl	klotho	0.445
Adrb1	adrenergic receptor, beta 1	0.425	Mouse
Lhx3	LIM homeobox protein 3	0.424
Vdr	vitamin D receptor	0.405
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.359
Cav1	caveolin 1, caveolae protein	0.359
Thrb	thyroid hormone receptor beta	0.313
Ghr	growth hormone receptor	0.277
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.268
Esr1	estrogen receptor 1 (alpha)	0.205
Pnpla2	patatin-like phospholipase domain containing 2	0.192
Lepr	leptin receptor	0.190
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.175	Mouse
Thra	thyroid hormone receptor alpha	0.165
Pgr	progesterone receptor	0.139
Npy2r	neuropeptide Y receptor Y2	0.123
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.119
Sstr4	somatostatin receptor 4	0.118	Mouse
Tgfb1	transforming growth factor, beta 1	0.117
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.116	Mouse
Oprm1	opioid receptor, mu 1	0.090
Pomc	pro-opiomelanocortin-alpha	0.083
Lep	leptin	0.082
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.081
Ar	androgen receptor	0.078
Crhr1	corticotropin releasing hormone receptor 1	0.075
Syn2	synapsin II	0.071
Kcnd1	potassium voltage-gated channel, Shal-related family, member 1	0.064
Kiss1	KiSS-1 metastasis-suppressor	0.062
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.062
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.060
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.059	Mouse
Adra2c	adrenergic receptor, alpha 2c	0.057	Mouse
Sstr1	somatostatin receptor 1	0.055	Mouse
Sstr2	somatostatin receptor 2	0.054	Mouse
Fshr	follicle stimulating hormone receptor	0.053
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.052
Grid1	glutamate receptor, ionotropic, delta 1	0.049
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.048
Esr2	estrogen receptor 2 (beta)	0.045
Nos1	nitric oxide synthase 1, neuronal	0.043
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.043
Pparg	peroxisome proliferator activated receptor gamma	0.041
Oprd1	opioid receptor, delta 1	0.041	Mouse
Gpr83	G protein-coupled receptor 83	0.040
Gpr3	G-protein coupled receptor 3	0.038
Cnr1	cannabinoid receptor 1 (brain)	0.036
ND6	NADH dehydrogenase subunit 6	0.035
Rgs9	regulator of G-protein signaling 9	0.033
Grm2	glutamate receptor, metabotropic 2	0.032
Trh	thyrotropin releasing hormone	0.032
Slc12a5	solute carrier family 12, member 5	0.031
Cga	glycoprotein hormones, alpha subunit	0.030
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.029
Gja5	gap junction protein, alpha 5	0.029
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.029	Mouse
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.028
Kcnk3	potassium channel, subfamily K, member 3	0.028
Hrh1	histamine receptor H1	0.027
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.026	Fly
Cntn4	contactin 4	0.026
Clcnka	chloride channel Ka	0.025
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.025
Fgf3	fibroblast growth factor 3	0.024
Gpr12	G-protein coupled receptor 12	0.024
Slc12a1	solute carrier family 12, member 1	0.023
Npy1r	neuropeptide Y receptor Y1	0.023
Cbl	Casitas B-lineage lymphoma	0.023
Grm8	glutamate receptor, metabotropic 8	0.023
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.023
Shc3	src homology 2 domain-containing transforming protein C3	0.022
Prop1	paired like homeodomain factor 1	0.021
Gast	gastrin	0.021
Adra1a	adrenergic receptor, alpha 1a	0.020	Fly
Tacr1	tachykinin receptor 1	0.020
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.020
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.020
Oprk1	opioid receptor, kappa 1	0.020	Mouse
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.019	Mouse
Sebox	SEBOX homeobox	0.017
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.017
Col4a3	collagen, type IV, alpha 3	0.017
Pax8	paired box gene 8	0.017
Neurog3	neurogenin 3	0.017
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.017
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.017
Rgs6	regulator of G-protein signaling 6	0.017
Il9r	interleukin 9 receptor	0.016
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.016
Plcb1	phospholipase C, beta 1	0.016
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.016
Drd3	dopamine receptor D3	0.016
Sstr3	somatostatin receptor 3	0.016	Mouse
Rcvrn	recoverin	0.016
Tbxa2r	thromboxane A2 receptor	0.016
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.016
Duox2	dual oxidase 2	0.015
Adora2a	adenosine A2a receptor	0.015
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.015
Cel	carboxyl ester lipase	0.015
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.014
Adrb2	adrenergic receptor, beta 2	0.014	Mouse
Gcgr	glucagon receptor	0.014
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.014
Nos3	nitric oxide synthase 3, endothelial cell	0.014
Adra2b	adrenergic receptor, alpha 2b	0.014	Mouse
Oxt	oxytocin	0.013
Prlhr	prolactin releasing hormone receptor	0.013
Krt12	keratin 12	0.013
Adra2a	adrenergic receptor, alpha 2a	0.013	Mouse
Npy5r	neuropeptide Y receptor Y5	0.013
Lhx6	LIM homeobox protein 6	0.013
Sult4a1	sulfotransferase family 4A, member 1	0.013
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.013
Galr2	galanin receptor 2	0.013	Mouse
Aatk	apoptosis-associated tyrosine kinase	0.013
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.013
Lin7b	lin-7 homolog B (C. elegans)	0.012
Gna11	guanine nucleotide binding protein, alpha 11	0.012	Mouse
Nhedc2	Na+/H+ exchanger domain containing 2	0.012
Irs2	insulin receptor substrate 2	0.012
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.012
Gpr27	G protein-coupled receptor 27	0.012
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.012
Cdh6	cadherin 6	0.012
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.012
Rit2	Ras-like without CAAX 2	0.012
Rgs4	regulator of G-protein signaling 4	0.011
Ikzf4	IKAROS family zinc finger 4	0.011
Tshr	thyroid stimulating hormone receptor	0.011
Ncoa1	nuclear receptor coactivator 1	0.011
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.011	Mouse
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.011
Gpr26	G protein-coupled receptor 26	0.011
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.011
Insr	insulin receptor	0.011
Olfr1264	olfactory receptor 1264	0.011
Otog	otogelin	0.011
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.011
Gucy2e	guanylate cyclase 2e	0.011
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.011
Hrh2	histamine receptor H2	0.011	Mouse
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.010
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.010
Syt6	synaptotagmin VI	0.010
Agrp	agouti related protein	0.010
Glra1	glycine receptor, alpha 1 subunit	0.010
Epb4.9	erythrocyte protein band 4.9	0.010
Vipr2	vasoactive intestinal peptide receptor 2	0.010
Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	0.010
Ncan	neurocan	0.010