IMP

Process View

Mus musculus

2 genes annotated in mouse

apoptotic process involved in outflow tract morphogenesis

Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "apoptotic process involved in outflow tract morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "apoptotic process involved in outflow tract morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Foxc1	forkhead box C1	1.000
Shh	sonic hedgehog	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Tbx1	T-box 1	1.000
Gli3	GLI-Kruppel family member GLI3	1.000
Tgfb2	transforming growth factor, beta 2	1.000
Bmp4	bone morphogenetic protein 4	1.000
Eya1	eyes absent 1 homolog (Drosophila)	1.000
Msx1	homeobox, msh-like 1	0.999
Tcfap2a	transcription factor AP-2, alpha	0.999
Fgf8	fibroblast growth factor 8	0.999
Sox9	SRY-box containing gene 9	0.999
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.999
Hand2	heart and neural crest derivatives expressed transcript 2	0.998
Prrx1	paired related homeobox 1	0.998
Foxc2	forkhead box C2	0.998
Pitx2	paired-like homeodomain transcription factor 2	0.998
Dlx5	distal-less homeobox 5	0.995
Pax2	paired box gene 2	0.994
Hand1	heart and neural crest derivatives expressed transcript 1	0.992
Pax3	paired box gene 3	0.991
Bmp7	bone morphogenetic protein 7	0.986
Gbx2	gastrulation brain homeobox 2	0.984
Foxa2	forkhead box A2	0.983	Mouse
Rarb	retinoic acid receptor, beta	0.976
Otx2	orthodenticle homolog 2 (Drosophila)	0.970
Smo	smoothened homolog (Drosophila)	0.970
Hoxa1	homeobox A1	0.959
Gsc	goosecoid homeobox	0.939
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.937
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.936
Msx2	homeobox, msh-like 2	0.915
Chrd	chordin	0.914
Ednra	endothelin receptor type A	0.910
Rarg	retinoic acid receptor, gamma	0.906
Jag1	jagged 1	0.902
Hoxa3	homeobox A3	0.890
Pax9	paired box gene 9	0.882
Runx2	runt related transcription factor 2	0.871
Fgfr1	fibroblast growth factor receptor 1	0.861
Fgfr3	fibroblast growth factor receptor 3	0.860
Pax8	paired box gene 8	0.851
Ctnnb1	catenin (cadherin associated protein), beta 1	0.820
Pax6	paired box gene 6	0.804
Pbx1	pre B-cell leukemia transcription factor 1	0.785
Prrx2	paired related homeobox 2	0.777
Zeb1	zinc finger E-box binding homeobox 1	0.762
Hoxa2	homeobox A2	0.750
Efnb2	ephrin B2	0.740
Gli2	GLI-Kruppel family member GLI2	0.645
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.632
Hoxd3	homeobox D3	0.616
Gata4	GATA binding protein 4	0.609
Mesp1	mesoderm posterior 1	0.597
Chd7	chromodomain helicase DNA binding protein 7	0.559
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.556
Foxg1	forkhead box G1	0.547	Mouse
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.536
Isl1	ISL1 transcription factor, LIM/homeodomain	0.532
Lmx1b	LIM homeobox transcription factor 1 beta	0.527
Vegfa	vascular endothelial growth factor A	0.512
Hmx3	H6 homeobox 3	0.510
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.506
Alx4	aristaless-like homeobox 4	0.503
Otx1	orthodenticle homolog 1 (Drosophila)	0.479
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.473
Meox2	mesenchyme homeobox 2	0.466
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.456
Alx1	ALX homeobox 1	0.446
Nog	noggin	0.442
Nkx3-2	NK3 homeobox 2	0.399
Dlx2	distal-less homeobox 2	0.396
Nkx2-1	NK2 homeobox 1	0.363
Ntf3	neurotrophin 3	0.360
Sox2	SRY-box containing gene 2	0.326
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.321
Lhx1	LIM homeobox protein 1	0.312
Emx2	empty spiracles homolog 2 (Drosophila)	0.311
Fgf10	fibroblast growth factor 10	0.307
Hoxd11	homeobox D11	0.297
Vangl2	vang-like 2 (van gogh, Drosophila)	0.284
Mecom	MDS1 and EVI1 complex locus	0.272
Rxra	retinoid X receptor alpha	0.264
Bmp2	bone morphogenetic protein 2	0.255
Emx1	empty spiracles homolog 1 (Drosophila)	0.234
Tgfbr2	transforming growth factor, beta receptor II	0.228
Tbx15	T-box 15	0.226
Foxf2	forkhead box F2	0.225
Dlx6	distal-less homeobox 6	0.181
Hoxa9	homeobox A9	0.168
Rara	retinoic acid receptor, alpha	0.160
Tbx10	T-box 10	0.159
Lmx1a	LIM homeobox transcription factor 1 alpha	0.158
Tcf21	transcription factor 21	0.153
Ece1	endothelin converting enzyme 1	0.151
Hoxb3	homeobox B3	0.145
Hoxd13	homeobox D13	0.145
Pitx1	paired-like homeodomain transcription factor 1	0.141
Pdx1	pancreatic and duodenal homeobox 1	0.135
Hmx1	H6 homeobox 1	0.132
Ptch1	patched homolog 1	0.128
Ihh	Indian hedgehog	0.127
Psen1	presenilin 1	0.123
Cdx1	caudal type homeobox 1	0.120
Foxa1	forkhead box A1	0.116	Mouse
Myod1	myogenic differentiation 1	0.111
Gdnf	glial cell line derived neurotrophic factor	0.106
Wnt1	wingless-related MMTV integration site 1	0.105
Mn1	meningioma 1	0.104
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.103
Acvr1	activin A receptor, type 1	0.101
Fgf3	fibroblast growth factor 3	0.098
Pou4f2	POU domain, class 4, transcription factor 2	0.098
Pten	phosphatase and tensin homolog	0.097
Rdh10	retinol dehydrogenase 10 (all-trans)	0.097
Gja1	gap junction protein, alpha 1	0.093
Neurog1	neurogenin 1	0.093
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.092
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.088
Foxi3	forkhead box I3	0.087
Gata6	GATA binding protein 6	0.084
Hoxa10	homeobox A10	0.081
Wnt3a	wingless-related MMTV integration site 3A	0.073
Egfr	epidermal growth factor receptor	0.073
Pax1	paired box gene 1	0.069
Matn3	matrilin 3	0.069
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.067
Hoxd9	homeobox D9	0.067
Wnt7a	wingless-related MMTV integration site 7A	0.066
Evx2	even skipped homeotic gene 2 homolog	0.066
Foxh1	forkhead box H1	0.065
Vax1	ventral anterior homeobox containing gene 1	0.065
Atoh1	atonal homolog 1 (Drosophila)	0.065
Fgfrl1	fibroblast growth factor receptor-like 1	0.063
Hoxb13	homeobox B13	0.060
Foxb1	forkhead box B1	0.058
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.058
Lhx3	LIM homeobox protein 3	0.057
Pthlh	parathyroid hormone-like peptide	0.056
Alx3	aristaless-like homeobox 3	0.056
Onecut1	one cut domain, family member 1	0.055
Hif1a	hypoxia inducible factor 1, alpha subunit	0.053
Hoxb1	homeobox B1	0.053
Hes5	hairy and enhancer of split 5 (Drosophila)	0.052
Hoxb6	homeobox B6	0.052
Emid2	EMI domain containing 2	0.052
Bnc1	basonuclin 1	0.050
Bdnf	brain derived neurotrophic factor	0.049
Dmrt3	doublesex and mab-3 related transcription factor 3	0.049
Pitx3	paired-like homeodomain transcription factor 3	0.049
Tbx3	T-box 3	0.048
T	brachyury	0.047
Adam17	a disintegrin and metallopeptidase domain 17	0.047
Sall3	sal-like 3 (Drosophila)	0.046
Hoxd10	homeobox D10	0.046
Sox3	SRY-box containing gene 3	0.045
Amh	anti-Mullerian hormone	0.044
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.044
Twist2	twist homolog 2 (Drosophila)	0.041
Adra2b	adrenergic receptor, alpha 2b	0.041
En1	engrailed 1	0.040
Myo15	myosin XV	0.039
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.038
Tlx3	T-cell leukemia, homeobox 3	0.037
Cldn2	claudin 2	0.036
Col2a1	collagen, type II, alpha 1	0.036
Tshz1	teashirt zinc finger family member 1	0.035
Sox4	SRY-box containing gene 4	0.035
Hoxa11	homeobox A11	0.035
Bmper	BMP-binding endothelial regulator	0.034
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.034
Hoxa4	homeobox A4	0.034
Hoxa5	homeobox A5	0.033
Cldn3	claudin 3	0.033
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.033
Hmx2	H6 homeobox 2	0.032
Rb1	retinoblastoma 1	0.032
Hes1	hairy and enhancer of split 1 (Drosophila)	0.032
Hoxb5	homeobox B5	0.030
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.030
Hoxb8	homeobox B8	0.029
Fshr	follicle stimulating hormone receptor	0.029
Irx1	Iroquois related homeobox 1 (Drosophila)	0.029
Figla	folliculogenesis specific basic helix-loop-helix	0.029
Cldn8	claudin 8	0.029
Lhx5	LIM homeobox protein 5	0.028
Foxd2	forkhead box D2	0.028	Mouse
Sall4	sal-like 4 (Drosophila)	0.028
Lrp6	low density lipoprotein receptor-related protein 6	0.027
Hoxa13	homeobox A13	0.027
Bmp5	bone morphogenetic protein 5	0.026
Cnga3	cyclic nucleotide gated channel alpha 3	0.026
Phlda2	pleckstrin homology-like domain, family A, member 2	0.026
Foxa3	forkhead box A3	0.026	Mouse
Hoxc8	homeobox C8	0.026
Hoxd1	homeobox D1	0.026
Tlx2	T-cell leukemia, homeobox 2	0.025
Evx1	even skipped homeotic gene 1 homolog	0.025
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.025
Sall1	sal-like 1 (Drosophila)	0.024
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.024
Fgf4	fibroblast growth factor 4	0.024
Dlx1	distal-less homeobox 1	0.024
Foxe3	forkhead box E3	0.024	Mouse
Nkx6-1	NK6 homeobox 1	0.024
Col13a1	collagen, type XIII, alpha 1	0.024
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.024
Zic2	zinc finger protein of the cerebellum 2	0.023
BC057022	cDNA sequence BC057022	0.023
Cdh1	cadherin 1	0.022
Sox11	SRY-box containing gene 11	0.022
Dmgdh	dimethylglycine dehydrogenase precursor	0.022
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.022
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.022
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.022
Pou4f3	POU domain, class 4, transcription factor 3	0.022
Hoxd4	homeobox D4	0.021
Lef1	lymphoid enhancer binding factor 1	0.021
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.021
Smad6	MAD homolog 6 (Drosophila)	0.021
Mep1a	meprin 1 alpha	0.021
Vsx2	visual system homeobox 2	0.020
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.020
Lefty1	left right determination factor 1	0.020
Insm1	insulinoma-associated 1	0.019
Snai1	snail homolog 1 (Drosophila)	0.019
Dhh	desert hedgehog	0.019
Pla2g10	phospholipase A2, group X	0.019
Uncx	UNC homeobox	0.019
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.019
Hnf1b	HNF1 homeobox B	0.019
Foxq1	forkhead box Q1	0.019	Mouse
Bik	BCL2-interacting killer	0.019
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.018
Hoxb9	homeobox B9	0.018
Hnf4a	hepatic nuclear factor 4, alpha	0.018
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.018
Hoxc6	homeobox C6	0.018
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.018
Esr1	estrogen receptor 1 (alpha)	0.018
Kremen2	kringle containing transmembrane protein 2	0.018
Hoxb7	homeobox B7	0.018
Sftpb	surfactant associated protein B	0.018
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.017
Tbx2	T-box 2	0.017
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.017
Tead3	TEA domain family member 3	0.017
Hoxb2	homeobox B2	0.017
Tbx5	T-box 5	0.017
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.017
Epx	eosinophil peroxidase	0.017
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.017
Gpr50	G-protein-coupled receptor 50	0.017
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.016
Notch1	Notch gene homolog 1 (Drosophila)	0.016
Zic1	zinc finger protein of the cerebellum 1	0.016
Etv2	ets variant gene 2	0.016
Neurog3	neurogenin 3	0.016
Mycs	myc-like oncogene, s-myc protein	0.016
Wnt2b	wingless related MMTV integration site 2b	0.016
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.015
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.015
Nobox	NOBOX oogenesis homeobox	0.015
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.015
Mlph	melanophilin	0.015
Wt1	Wilms tumor 1 homolog	0.015
Gata3	GATA binding protein 3	0.015
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.015
Tcfap2c	transcription factor AP-2, gamma	0.015
Sox1	SRY-box containing gene 1	0.015
Rax	retina and anterior neural fold homeobox	0.015
Mapk15	mitogen-activated protein kinase 15	0.015
Hif3a	hypoxia inducible factor 3, alpha subunit	0.015
Wnt5b	wingless-related MMTV integration site 5B	0.015
Nodal	nodal	0.015
Barx1	BarH-like homeobox 1	0.014
Cct6b	chaperonin containing Tcp1, subunit 6b (zeta)	0.014
Proc	protein C	0.014
Rhpn1	rhophilin, Rho GTPase binding protein 1	0.014
Pcdh12	protocadherin 12	0.014
Hoxd8	homeobox D8	0.014
Pou2f3	POU domain, class 2, transcription factor 3	0.014
Fzd10	frizzled homolog 10 (Drosophila)	0.014
Col22a1	collagen, type XXII, alpha 1	0.014
Zfp503	zinc finger protein 503	0.014
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.014
Tal2	T-cell acute lymphocytic leukemia 2	0.014
Apob	apolipoprotein B	0.014
Amhr2	anti-Mullerian hormone type 2 receptor	0.014
Gdf7	growth differentiation factor 7	0.013
Ctf1	cardiotrophin 1	0.013
Elf3	E74-like factor 3	0.013
Shox2	short stature homeobox 2	0.013
Gcgr	glucagon receptor	0.013
Miox	myo-inositol oxygenase	0.013
Gsx1	GS homeobox 1	0.013
Ebf3	early B-cell factor 3	0.013
Sp5	trans-acting transcription factor 5	0.013
Apoa5	apolipoprotein A-V	0.013
F12	coagulation factor XII (Hageman factor)	0.013
Cbln3	cerebellin 3 precursor protein	0.013
Fgfr4	fibroblast growth factor receptor 4	0.013
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.013
Olfr70	olfactory receptor 70	0.013
Prr15	proline rich 15	0.013
Mmp24	matrix metallopeptidase 24	0.013
Hmga2	high mobility group AT-hook 2	0.012
Spdef	SAM pointed domain containing ets transcription factor	0.012
BC021785	cDNA sequence BC021785	0.012
Gas1	growth arrest specific 1	0.012
Zfp771	zinc finger protein 771	0.012
Irx3	Iroquois related homeobox 3 (Drosophila)	0.012
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.012
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.012
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.012
Twist1	twist homolog 1 (Drosophila)	0.012
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.012
Hes3	hairy and enhancer of split 3 (Drosophila)	0.012
Lyzl4	lysozyme-like 4	0.012
Fgf15	fibroblast growth factor 15	0.012
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.011
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.011
G6pc2	glucose-6-phosphatase, catalytic, 2	0.011
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.011
BC021891	cDNA sequence BC021891	0.011
Kl	klotho	0.011
Tulp2	tubby-like protein 2	0.011
Inhbe	inhibin beta E	0.011
Npr3	natriuretic peptide receptor 3	0.011
Pou3f2	POU domain, class 3, transcription factor 2	0.011
Cldn6	claudin 6	0.011
Wnt9b	wingless-type MMTV integration site 9B	0.011
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.011
Klf5	Kruppel-like factor 5	0.011
Sim2	single-minded homolog 2 (Drosophila)	0.011
Apaf1	apoptotic peptidase activating factor 1	0.011
Myf5	myogenic factor 5	0.011
Pou3f3	POU domain, class 3, transcription factor 3	0.011
Vstm2b	V-set and transmembrane domain containing 2B	0.011
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.011
Hapln1	hyaluronan and proteoglycan link protein 1	0.011
Zfpm2	zinc finger protein, multitype 2	0.011
Lrp2	low density lipoprotein receptor-related protein 2	0.011
Ambn	ameloblastin	0.011
Fam65c	family with sequence similarity 65, member C	0.011
Fev	FEV (ETS oncogene family)	0.011
Nf1	neurofibromatosis 1	0.011
Hmga1	high mobility group AT-hook 1	0.011
Col11a1	collagen, type XI, alpha 1	0.011
Pyy	peptide YY	0.011
Foxl2	forkhead box L2	0.010	Mouse
Neurog2	neurogenin 2	0.010
Sox21	SRY-box containing gene 21	0.010
Vax2	ventral anterior homeobox containing gene 2	0.010
Ptf1a	pancreas specific transcription factor, 1a	0.010
Gjb1	gap junction protein, beta 1	0.010
Mnx1	motor neuron and pancreas homeobox 1	0.010
Foxe1	forkhead box E1	0.010	Mouse
Mdfi	MyoD family inhibitor	0.010
Klf3	Kruppel-like factor 3 (basic)	0.010
Tcl1	T-cell lymphoma breakpoint 1	0.010
Fuz	fuzzy homolog (Drosophila)	0.010
Inhbc	inhibin beta-C	0.010
Sva	seminal vesicle antigen	0.010
Dhrsx	dehydrogenase/reductase (SDR family) X chromosome	0.010
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.010
Cldn4	claudin 4	0.010
Pigr	polymeric immunoglobulin receptor	0.010
Lhb	luteinizing hormone beta	0.010
Onecut3	one cut domain, family member 3	0.010
Skor1	SKI family transcriptional corepressor 1	0.010