IMP

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Mus musculus

21 genes annotated in mouse

macroautophagy

The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane-bounded autophagic bodies which are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "macroautophagy"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "macroautophagy" (in gray)

Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	1.000
Atg12	autophagy-related 12 (yeast)	1.000
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	1.000	Fly
Sqstm1	sequestosome 1	0.999	Human
Ulk1	Unc-51 like kinase 1 (C. elegans)	0.979
Rb1	retinoblastoma 1	0.960
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.926
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.919
Braf	Braf transforming gene	0.910	Fly
Mdm2	transformed mouse 3T3 cell double minute 2	0.882
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.829
Nf1	neurofibromatosis 1	0.682
Atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.571
Pef1	penta-EF hand domain containing 1	0.513
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.497
Ncstn	nicastrin	0.496
Raf1	v-raf-leukemia viral oncogene 1	0.480	Fly
Lepr	leptin receptor	0.466
Grb10	growth factor receptor bound protein 10	0.450
Foxa2	forkhead box A2	0.434	Worm
Apc	adenomatosis polyposis coli	0.429
Rnf167	ring finger protein 167	0.426
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.396
Pparg	peroxisome proliferator activated receptor gamma	0.362
Ctnnb1	catenin (cadherin associated protein), beta 1	0.352
Gabarap	gamma-aminobutyric acid receptor associated protein	0.344
Mapkap1	mitogen-activated protein kinase associated protein 1	0.337
Rptor	regulatory associated protein of MTOR, complex 1	0.336	Worm
Atg7	autophagy-related 7 (yeast)	0.322	Fly
Dctn2	dynactin 2	0.321
Notch2	Notch gene homolog 2 (Drosophila)	0.315
Atf2	activating transcription factor 2	0.313
Sesn2	sestrin 2	0.308
Abtb1	ankyrin repeat and BTB (POZ) domain containing 1	0.300
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.282
Aamp	angio-associated migratory protein	0.280
Rictor	RPTOR independent companion of MTOR, complex 2	0.280
Atg3	autophagy-related 3 (yeast)	0.275
Mlf2	myeloid leukemia factor 2	0.264
Irs2	insulin receptor substrate 2	0.255
Wbp2	WW domain binding protein 2	0.248
Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1	0.232
Hif1a	hypoxia inducible factor 1, alpha subunit	0.225
Tsc2	tuberous sclerosis 2	0.215
Esr1	estrogen receptor 1 (alpha)	0.212
Fam134a	family with sequence similarity 134, member A	0.208
Ar	androgen receptor	0.207
Fkbp8	FK506 binding protein 8	0.203
Ufd1l	ubiquitin fusion degradation 1 like	0.198
Rpgrip1l	Rpgrip1-like	0.189
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.187
Sav1	salvador homolog 1 (Drosophila)	0.186
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.177
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.174
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.165
Pik3c3	phosphoinositide-3-kinase, class 3	0.163
Bsg	basigin	0.157
Cyld	cylindromatosis (turban tumor syndrome)	0.152
Gabarapl1	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1	0.137
Mapk1	mitogen-activated protein kinase 1	0.137	Fly
Foxo3	forkhead box O3	0.136	Fly
Mdm4	transformed mouse 3T3 cell double minute 4	0.136
Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)	0.134
Rps3	ribosomal protein S3	0.131
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.131
Ift57	intraflagellar transport 57 homolog (Chlamydomonas)	0.127
Ypel3	yippee-like 3 (Drosophila)	0.126
Notch1	Notch gene homolog 1 (Drosophila)	0.119
Igf2r	insulin-like growth factor 2 receptor	0.118
Npc1	Niemann Pick type C1	0.117
Kif3a	kinesin family member 3A	0.112
Sh3glb2	SH3-domain GRB2-like endophilin B2	0.112
Atg5	autophagy-related 5 (yeast)	0.111
Chmp1a	chromatin modifying protein 1A	0.109
Mapk14	mitogen-activated protein kinase 14	0.107
Foxo1	forkhead box O1	0.105	Fly
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.105
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.104
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.103
Aes	amino-terminal enhancer of split	0.100
Rfwd2	ring finger and WD repeat domain 2	0.099
Tbc1d17	TBC1 domain family, member 17	0.096
Usp5	ubiquitin specific peptidase 5 (isopeptidase T)	0.091
Trp53inp2	transformation related protein 53 inducible nuclear protein 2	0.091
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.089
Vps26b	vacuolar protein sorting 26 homolog B (yeast)	0.088
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.085
Wdr45	WD repeat domain 45	0.085
Rab14	RAB14, member RAS oncogene family	0.084
Psap	prosaposin	0.084
Trp53	transformation related protein 53	0.083
Spns1	spinster homolog 1 (Drosophila)	0.083
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.081
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.081
Smad2	MAD homolog 2 (Drosophila)	0.080
Mapk3	mitogen-activated protein kinase 3	0.079	Fly
Trp73	transformation related protein 73	0.079	Mouse Fly
Tecr	trans-2,3-enoyl-CoA reductase	0.079
Kiss1	KiSS-1 metastasis-suppressor	0.078
Kit	kit oncogene	0.078
Dhrs1	dehydrogenase/reductase (SDR family) member 1	0.077
Keap1	kelch-like ECH-associated protein 1	0.074
Atxn1	ataxin 1	0.074
Zbtb24	zinc finger and BTB domain containing 24	0.072
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.071
Rpl8	ribosomal protein L8	0.069
Nrbp1	nuclear receptor binding protein 1	0.068
Mitf	microphthalmia-associated transcription factor	0.066
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.065
Smad4	MAD homolog 4 (Drosophila)	0.064
Kl	klotho	0.063
Ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.063
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.062
Rab5a	RAB5A, member RAS oncogene family	0.061
Pex5	peroxisomal biogenesis factor 5	0.058
Naga	N-acetyl galactosaminidase, alpha	0.058
Plaa	phospholipase A2, activating protein	0.058
Narf	nuclear prelamin A recognition factor	0.058
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.057
Ubap1	ubiquitin-associated protein 1	0.056
Fis1	fission 1 (mitochondrial outer membrane) homolog (yeast)	0.055
Ptch1	patched homolog 1	0.053
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.052
Usp8	ubiquitin specific peptidase 8	0.051
Vdr	vitamin D receptor	0.051
Ctsb	cathepsin B	0.050
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.049
Edem2	ER degradation enhancer, mannosidase alpha-like 2	0.049
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.048
Wbp1	WW domain binding protein 1	0.046
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.046
Eif2ak1	eukaryotic translation initiation factor 2 alpha kinase 1	0.044
Pld3	phospholipase D family, member 3	0.044
Cdx2	caudal type homeobox 2	0.044
Mecp2	methyl CpG binding protein 2	0.044
Rb1cc1	RB1-inducible coiled-coil 1	0.043
Fbxw7	F-box and WD-40 domain protein 7	0.043
Klc4	kinesin light chain 4	0.043
Gipc1	GIPC PDZ domain containing family, member 1	0.042
Stk11	serine/threonine kinase 11	0.042
Mgrn1	mahogunin, ring finger 1	0.042
Ykt6	YKT6 homolog (S. Cerevisiae)	0.041
Bsdc1	BSD domain containing 1	0.041
Map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.041	Rat
Prlr	prolactin receptor	0.040
Cyth2	cytohesin 2	0.040
Ep300	E1A binding protein p300	0.040
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.039
Mapk9	mitogen-activated protein kinase 9	0.039
Abhd12	abhydrolase domain containing 12	0.039
Cadps2	Ca2+-dependent activator protein for secretion 2	0.039
Mapre3	microtubule-associated protein, RP/EB family, member 3	0.039
1110008P14Rik	RIKEN cDNA 1110008P14 gene	0.039
Wdr81	WD repeat domain 81	0.038
Ap3s1	adaptor-related protein complex 3, sigma 1 subunit	0.038
Agtr1a	angiotensin II receptor, type 1a	0.038
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.038
Ap1s1	adaptor protein complex AP-1, sigma 1	0.037
Ubc	ubiquitin C	0.037
Ptp4a2	protein tyrosine phosphatase 4a2	0.037
Map2k2	mitogen-activated protein kinase kinase 2	0.037
Arl8b	ADP-ribosylation factor-like 8B	0.037
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.037
Vhl	von Hippel-Lindau tumor suppressor	0.036
Ptms	parathymosin	0.036
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.036
Rnf103	ring finger protein 103	0.036
Tsc1	tuberous sclerosis 1	0.035
Ep400	E1A binding protein p400	0.035
Lamp1	lysosomal-associated membrane protein 1	0.035
Igbp1	immunoglobulin (CD79A) binding protein 1	0.034
Napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.034
Rplp0	ribosomal protein, large, P0	0.034
Nbr1	neighbor of Brca1 gene 1	0.034	Human
Dctn1	dynactin 1	0.033
Inpp5k	inositol polyphosphate 5-phosphatase K	0.033
Clock	circadian locomotor output cycles kaput	0.033
Optn	optineurin	0.032
Flot2	flotillin 2	0.032
Brap	BRCA1 associated protein	0.032
Smpd2	sphingomyelin phosphodiesterase 2, neutral	0.032
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.032
Gopc	golgi associated PDZ and coiled-coil motif containing	0.032
Apeh	acylpeptide hydrolase	0.032
Csnk1g2	casein kinase 1, gamma 2	0.032
Sept7	septin 7	0.032
Pex19	peroxisomal biogenesis factor 19	0.031
Arcn1	archain 1	0.031
Slc27a4	solute carrier family 27 (fatty acid transporter), member 4	0.031
Stx6	syntaxin 6	0.031
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.031
Usf2	upstream transcription factor 2	0.031
Ftl2	ferritin light chain 2	0.031
Stx12	syntaxin 12	0.030
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.030
Zyg11b	zyg-ll homolog B (C. elegans)	0.030
Pip4k2c	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma	0.030
Stambp	STAM binding protein	0.029
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.029
Ap2s1	adaptor-related protein complex 2, sigma 1 subunit	0.029
Arf5	ADP-ribosylation factor 5	0.029	Yeast
Gm16517	predicted gene, Gm16517	0.029
Dcaf11	DDB1 and CUL4 associated factor 11	0.029
Ccndbp1	cyclin D-type binding-protein 1	0.028
Ap1b1	adaptor protein complex AP-1, beta 1 subunit	0.028
Zfyve26	zinc finger, FYVE domain containing 26	0.028
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.027
Flcn	folliculin	0.027
Slc25a10	solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10	0.027
Prkce	protein kinase C, epsilon	0.027
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.027
Atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	0.026
C78339	expressed sequence C78339	0.026
Atg10	autophagy-related 10 (yeast)	0.026
Rala	v-ral simian leukemia viral oncogene homolog A (ras related)	0.026
Pcmtd2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	0.026
Capns1	calpain, small subunit 1	0.025
Gpr108	G protein-coupled receptor 108	0.025
Map2k4	mitogen-activated protein kinase kinase 4	0.025
Kpna1	karyopherin (importin) alpha 1	0.025
Ccdc64b	coiled-coil domain containing 64B	0.024
Cav1	caveolin 1, caveolae protein	0.024
Asb8	ankyrin repeat and SOCS box-containing 8	0.024
Hdac5	histone deacetylase 5	0.024
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.024
Ctsa	cathepsin A	0.024
Pfkl	phosphofructokinase, liver, B-type	0.024
Bet1l	blocked early in transport 1 homolog (S. cerevisiae)-like	0.023
Ctnnbip1	catenin beta interacting protein 1	0.023
Rnf214	ring finger protein 214	0.023
Ube2o	ubiquitin-conjugating enzyme E2O	0.023
Mapk8	mitogen-activated protein kinase 8	0.023
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.023
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.023
Gsk3b	glycogen synthase kinase 3 beta	0.023
Cand1	cullin associated and neddylation disassociated 1	0.023
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.023
Tpp1	tripeptidyl peptidase I	0.023
Fbxo38	F-box protein 38	0.023
Clcn4-2	chloride channel 4-2	0.023
Ahr	aryl-hydrocarbon receptor	0.022
Hras1	Harvey rat sarcoma virus oncogene 1	0.022	Fly
Men1	multiple endocrine neoplasia 1	0.022
Clptm1	cleft lip and palate associated transmembrane protein 1	0.022
2310035K24Rik	RIKEN cDNA 2310035K24 gene	0.022
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.022
Ghr	growth hormone receptor	0.021
Smpd1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.021
Dmtf1	cyclin D binding myb-like transcription factor 1	0.021
Irf6	interferon regulatory factor 6	0.021
Dclre1a	DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)	0.021
Mtpn	myotrophin	0.021
Mapre1	microtubule-associated protein, RP/EB family, member 1	0.021
Ergic3	ERGIC and golgi 3	0.021
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.021
Arid1b	AT rich interactive domain 1B (SWI-like)	0.021
Emx1	empty spiracles homolog 1 (Drosophila)	0.021
Rnf14	ring finger protein 14	0.021
Tk2	thymidine kinase 2, mitochondrial	0.020
Wdfy2	WD repeat and FYVE domain containing 2	0.020
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.020
Siae	sialic acid acetylesterase	0.020
2510006D16Rik	RIKEN cDNA 2510006D16 gene	0.020
Rab7	RAB7, member RAS oncogene family	0.020
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform	0.020
Yap1	yes-associated protein 1	0.020
9430023L20Rik	RIKEN cDNA 9430023L20 gene	0.019
Cpeb4	cytoplasmic polyadenylation element binding protein 4	0.019
Mcm9	minichromosome maintenance complex component 9	0.019
Rint1	RAD50 interactor 1	0.019
Foxa1	forkhead box A1	0.019	Worm
Renbp	renin binding protein	0.019
Ip6k1	inositol hexaphosphate kinase 1	0.019
Akt1	thymoma viral proto-oncogene 1	0.019
Nf2	neurofibromatosis 2	0.019
Rps2	ribosomal protein S2	0.018
Morf4l2	mortality factor 4 like 2	0.018
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.018
Tab3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.018
Impad1	inositol monophosphatase domain containing 1	0.018
March6	membrane-associated ring finger (C3HC4) 6	0.018
Fst	follistatin	0.018
2700078K21Rik	RIKEN cDNA 2700078K21 gene	0.018
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.018
Rap1b	RAS related protein 1b	0.018
Psen1	presenilin 1	0.018
Dpp7	dipeptidylpeptidase 7	0.018
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.018
Hectd3	HECT domain containing 3	0.018
Igf1	insulin-like growth factor 1	0.018
Ngly1	N-glycanase 1	0.017
Fbxw5	F-box and WD-40 domain protein 5	0.017
Flot1	flotillin 1	0.017
Mark3	MAP/microtubule affinity-regulating kinase 3	0.017
Tcn2	transcobalamin 2	0.017
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.017
Slu7	SLU7 splicing factor homolog (S. cerevisiae)	0.017
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.017
Fxr2	fragile X mental retardation, autosomal homolog 2	0.017
Mcoln1	mucolipin 1	0.017	Fly
Xpa	xeroderma pigmentosum, complementation group A	0.017
Ptgs2	prostaglandin-endoperoxide synthase 2	0.017
Tmub2	transmembrane and ubiquitin-like domain containing 2	0.017
Cog4	component of oligomeric golgi complex 4	0.017
Cdh1	cadherin 1	0.017
Rab1b	RAB1B, member RAS oncogene family	0.017	Human Mouse
Med1	mediator complex subunit 1	0.016
Max	Max protein	0.016
Shank2	SH3/ankyrin domain gene 2	0.016
Sgpl1	sphingosine phosphate lyase 1	0.016
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.016
Rab8a	RAB8A, member RAS oncogene family	0.016	Mouse
Fbxl20	F-box and leucine-rich repeat protein 20	0.016
Dsg1a	desmoglein 1 alpha	0.016
Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha isoform	0.016
Oaz2-ps	ornithine decarboxylase antizyme 2, pseudogene	0.016
Stam2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.016
Zfyve1	zinc finger, FYVE domain containing 1	0.016
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.016
2410001C21Rik	RIKEN cDNA 2410001C21 gene	0.016
Aip	aryl-hydrocarbon receptor-interacting protein	0.016
Rxra	retinoid X receptor alpha	0.016
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.016
Ap2b1	adaptor-related protein complex 2, beta 1 subunit	0.016
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.016
Pycard	PYD and CARD domain containing	0.016
Atp9a	ATPase, class II, type 9A	0.015
Stx5a	syntaxin 5A	0.015
Coro1b	coronin, actin binding protein 1B	0.015
Unc50	unc-50 homolog (C. elegans)	0.015
Slc25a44	solute carrier family 25, member 44	0.015
Nprl3	nitrogen permease regulator-like 3 (S. cerevisiae)	0.015
Homer1	homer homolog 1 (Drosophila)	0.015
Osbpl2	oxysterol binding protein-like 2	0.015
Ap1g1	adaptor protein complex AP-1, gamma 1 subunit	0.015
Tcf25	transcription factor 25 (basic helix-loop-helix)	0.015
Rora	RAR-related orphan receptor alpha	0.015
Zfp954	zinc finger protein 954	0.015
Hadha	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	0.015
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.015
Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	0.015
Pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	0.015
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	0.015
Cltc	clathrin, heavy polypeptide (Hc)	0.014
Rap2a	RAS related protein 2a	0.014
0610007P14Rik	RIKEN cDNA 0610007P14 gene	0.014
Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	0.014
Ftl1	ferritin light chain 1	0.014
1500003O03Rik	RIKEN cDNA 1500003O03 gene	0.014
Irs1	insulin receptor substrate 1	0.014
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.014
Capn1	calpain 1	0.014
Yipf5	Yip1 domain family, member 5	0.014
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.014
Sdccag3	serologically defined colon cancer antigen 3	0.014
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.014
Btbd10	BTB (POZ) domain containing 10	0.014
Telo2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.014
Sec22b	SEC22 vesicle trafficking protein homolog B (S. cerevisiae)	0.014
Ppil2	peptidylprolyl isomerase (cyclophilin)-like 2	0.014
Tollip	toll interacting protein	0.014
Mlx	MAX-like protein X	0.014
Fbxo25	F-box protein 25	0.014
Grm1	glutamate receptor, metabotropic 1	0.013
Rtn3	reticulon 3	0.013
Senp2	SUMO/sentrin specific peptidase 2	0.013
Ubxn4	UBX domain protein 4	0.013
Rhot2	ras homolog gene family, member T2	0.013
Uso1	USO1 homolog, vesicle docking protein (yeast)	0.013
Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	0.013
Ezh1	enhancer of zeste homolog 1 (Drosophila)	0.013
Gdap2	ganglioside-induced differentiation-associated-protein 2	0.013
Arf1	ADP-ribosylation factor 1	0.013
Zfand2b	zinc finger, AN1 type domain 2B	0.013
Ipo13	importin 13	0.013
Sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.013
Fam13b	family with sequence similarity 13, member B	0.013
Pdia3	protein disulfide isomerase associated 3	0.013
Eef2	eukaryotic translation elongation factor 2	0.013
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.013
Mks1	Meckel syndrome, type 1	0.013
Caml	calcium modulating ligand	0.013
Hbp1	high mobility group box transcription factor 1	0.013
Adamdec1	ADAM-like, decysin 1	0.013
Kif5b	kinesin family member 5B	0.013
Abca3	ATP-binding cassette, sub-family A (ABC1), member 3	0.013
Plbd2	phospholipase B domain containing 2	0.013
Ube4a	ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)	0.013
Cenpb	centromere protein B	0.012
Edem3	ER degradation enhancer, mannosidase alpha-like 3	0.012
Epn1	epsin 1	0.012
Mtap2	microtubule-associated protein 2	0.012
Wwox	WW domain-containing oxidoreductase	0.012
Fastk	Fas-activated serine/threonine kinase	0.012
Ssr3	signal sequence receptor, gamma	0.012
Vta1	Vps20-associated 1 homolog (S. cerevisiae)	0.012
Zrsr1	zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1	0.012
2010011I20Rik	RIKEN cDNA 2010011I20 gene	0.012
Ap2m1	adaptor protein complex AP-2, mu1	0.012
Rps5	ribosomal protein S5	0.012
Akap8l	A kinase (PRKA) anchor protein 8-like	0.012
Nub1	negative regulator of ubiquitin-like proteins 1	0.012
Clcn7	chloride channel 7	0.012
1810031K17Rik	RIKEN cDNA 1810031K17 gene	0.012
Tprgl	transformation related protein 63 regulated like	0.012
Foxp1	forkhead box P1	0.012
Cstf2t	cleavage stimulation factor, 3' pre-RNA subunit 2, tau	0.012
Trpc4ap	transient receptor potential cation channel, subfamily C, member 4 associated protein	0.012
Tmem30b	transmembrane protein 30B	0.012
Sepx1	selenoprotein X 1	0.012
Mkrn1	makorin, ring finger protein, 1	0.012
Ncor1	nuclear receptor co-repressor 1	0.012
Erlin2	ER lipid raft associated 2	0.012
Igf2	insulin-like growth factor 2	0.012
Myh10	myosin, heavy polypeptide 10, non-muscle	0.012
Cdk5	cyclin-dependent kinase 5	0.012
Cdcp1	CUB domain containing protein 1	0.012
Runx1	runt related transcription factor 1	0.012
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.012
Sec23a	SEC23A (S. cerevisiae)	0.012
Rab24	RAB24, member RAS oncogene family	0.011
Rab11a	RAB11a, member RAS oncogene family	0.011
Ccpg1	cell cycle progression 1	0.011
Cldn2	claudin 2	0.011
Bag6	BCL2-associated athanogene 6	0.011
Ift81	intraflagellar transport 81 homolog (Chlamydomonas)	0.011
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.011
Pmm1	phosphomannomutase 1	0.011
Phf1	PHD finger protein 1	0.011
Ubb	ubiquitin B	0.011
Mapk6	mitogen-activated protein kinase 6	0.011
Zfp40	zinc finger protein 40	0.011
Usp15	ubiquitin specific peptidase 15	0.011
Ccnd1	cyclin D1	0.011
Mier3	mesoderm induction early response 1, family member 3	0.011
Arid5b	AT rich interactive domain 5B (MRF1-like)	0.011
Rnf10	ring finger protein 10	0.011
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.011
Tmem19	transmembrane protein 19	0.011
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.011
Pnpla2	patatin-like phospholipase domain containing 2	0.011
Rraga	Ras-related GTP binding A	0.011
Vamp4	vesicle-associated membrane protein 4	0.011
Bcl2l1	BCL2-like 1	0.011
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.011
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.011
Klf5	Kruppel-like factor 5	0.011
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.011
Adck4	aarF domain containing kinase 4	0.011
Bre	brain and reproductive organ-expressed protein	0.011
Tmem134	transmembrane protein 134	0.011
Rnasek	ribonuclease, RNase K	0.011
Cables2	CDK5 and Abl enzyme substrate 2	0.011
Ctsl	cathepsin L	0.011
Plcg1	phospholipase C, gamma 1	0.011
Yipf1	Yip1 domain family, member 1	0.011
Slc25a38	solute carrier family 25, member 38	0.011
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.011
Map2k5	mitogen-activated protein kinase kinase 5	0.010
Ncoa6	nuclear receptor coactivator 6	0.010
A630007B06Rik	RIKEN cDNA A630007B06 gene	0.010
Lypla2	lysophospholipase 2	0.010
Gaa	glucosidase, alpha, acid	0.010
Spsb3	splA/ryanodine receptor domain and SOCS box containing 3	0.010
Vps24	vacuolar protein sorting 24 (yeast)	0.010
Wdr26	WD repeat domain 26	0.010
Ciao1	cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)	0.010
Man2b1	mannosidase 2, alpha B1	0.010
Actr8	ARP8 actin-related protein 8 homolog (S. cerevisiae)	0.010
Pitpnb	phosphatidylinositol transfer protein, beta	0.010
Rbl2	retinoblastoma-like 2	0.010
Rpl10	ribosomal protein 10	0.010
Gabarapl2	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2	0.010
Cmpk1	cytidine monophosphate (UMP-CMP) kinase 1	0.010
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.010
Otub1	OTU domain, ubiquitin aldehyde binding 1	0.010
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.010
Nprl2	nitrogen permease regulator-like 2 (S. cerevisiae)	0.010
Mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.010
Vps11	vacuolar protein sorting 11 (yeast)	0.010
Rspry1	ring finger and SPRY domain containing 1	0.010