IMP

Process View

Rattus norvegicus

2 genes annotated in rat

regulation of arp2 3 complex mediated actin nucleation

Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of arp2 3 complex mediated actin nucleation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of arp2 3 complex mediated actin nucleation" (in gray)

Name	Description	Probability	Func Analog Organism
Pfn1	profilin 1	0.532
Serp1	stress-associated endoplasmic reticulum protein 1	0.484
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.356
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.184
Efhd2	EF-hand domain family, member D2	0.137
Limd2	LIM domain containing 2	0.132
Ap2s1	adaptor-related protein complex 2, sigma 1 subunit	0.129
Sdcbp	syndecan binding protein	0.119
Ppp2r4	protein phosphatase 2A activator, regulatory subunit 4	0.087
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.086
Usf1	upstream transcription factor 1	0.083
Laptm5	lysosomal protein transmembrane 5	0.082
Cops7a	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	0.080
Coro1a	coronin, actin binding protein 1A	0.080	Yeast
Dbnl	drebrin-like	0.069
RGD1311122	similar to RIKEN cDNA 1110003E01	0.069
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.063
Wdr1	WD repeat domain 1	0.060
Dgkz	diacylglycerol kinase zeta	0.059
RT1-DMa	RT1 class II, locus DMa	0.059
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.052
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.052
Pcnxl3	pecanex-like 3 (Drosophila)	0.050
Eif4e	eukaryotic translation initiation factor 4E	0.048
Rap1b	RAP1B, member of RAS oncogene family	0.047
Rab2a	RAB2A, member RAS oncogene family	0.041
Ap2b1	adaptor-related protein complex 2, beta 1 subunit	0.041
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.038
Ap1s1	adaptor-related protein complex 1, sigma 1 subunit	0.036
Pycard	PYD and CARD domain containing	0.036
Plek	pleckstrin	0.036
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.035
Akt1	v-akt murine thymoma viral oncogene homolog 1	0.034
Cdk4	cyclin-dependent kinase 4	0.034
Cmpk1	cytidine monophosphate (UMP-CMP) kinase 1	0.033
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.032
Tubb5	tubulin, beta 5	0.031
Nsf	N-ethylmaleimide-sensitive factor	0.030
Rhog	ras homolog gene family, member G (rho G)	0.029
Glipr1	GLI pathogenesis-related 1	0.029
Gnb5	guanine nucleotide binding protein (G protein), beta 5	0.028
Pik3r2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.028
RT1-DMb	RT1 class II, locus DMb	0.028
Arf5	ADP-ribosylation factor 5	0.027	Rat
Obscn	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.026
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform	0.025
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.024
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.024
Clic1	chloride intracellular channel 1	0.024
Ttc3	tetratricopeptide repeat domain 3	0.024
March5	membrane-associated ring finger (C3HC4) 5	0.024
Rab7a	RAB7A, member RAS oncogene family	0.024
Rac2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.024
Ptbp1	polypyrimidine tract binding protein 1	0.024
Copb1	coatomer protein complex, subunit beta 1	0.024
Morf4l2	mortality factor 4 like 2	0.023
Coro1b	coronin, actin-binding protein, 1B	0.023	Human Yeast
Arpc2	actin related protein 2/3 complex, subunit 2	0.023
Hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.023
Rab6a	RAB6A, member RAS oncogene family	0.022
Prelid1	PRELI domain containing 1	0.022
Ergic3	ERGIC and golgi 3	0.022
Snrpb	small nuclear ribonucleoprotein polypeptides B and B1	0.022
Ids	iduronate 2-sulfatase	0.022
Plac8	placenta-specific 8	0.022
Calr	calreticulin	0.021
Mospd3	motile sperm domain containing 3	0.021
Cd82	Cd82 molecule	0.021
Nudt21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.020
Azin1	antizyme inhibitor 1	0.020
Arf4	ADP-ribosylation factor 4	0.020	Rat
Rgs10	regulator of G-protein signaling 10	0.020
Atp6v1b2	ATPase, H transporting, lysosomal V1 subunit B2	0.020
Prr13	proline rich 13	0.020
Myh10	myosin, heavy chain 10, non-muscle	0.020
Cd53	Cd53 molecule	0.019
Rab11b	RAB11B, member RAS oncogene family	0.019
Ifrd1	interferon-related developmental regulator 1	0.019
Gria2	glutamate receptor, ionotropic, AMPA 2	0.019
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.019
Spn	sialophorin	0.018
Slc4a2	solute carrier family 4 (anion exchanger), member 2	0.018
Eif5a	eukaryotic translation initiation factor 5A	0.018
Lcp1	lymphocyte cytosolic protein 1	0.018
Cotl1	coactosin-like 1 (Dictyostelium)	0.018
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.017
Ubqln1	ubiquilin 1	0.017
Csnk1g2	casein kinase 1, gamma 2	0.017
Ppp2cb	protein phosphatase 2, catalytic subunit, beta isoform	0.017
Ppp4c	protein phosphatase 4, catalytic subunit	0.017
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.017
Irf1	interferon regulatory factor 1	0.017
Olfm1	olfactomedin 1	0.017
Arpc1b	actin related protein 2/3 complex, subunit 1B	0.017
Prkar1a	protein kinase, cAMP-dependent, regulatory, type I, alpha	0.017
Uso1	USO1 homolog, vesicle docking protein (yeast)	0.017
Aldh16a1	aldehyde dehydrogenase 16 family, member A1	0.016
Litaf	lipopolysaccharide-induced TNF factor	0.016
Gria3	glutamate receptor, ionotrophic, AMPA 3	0.016
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.016
Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase	0.016
Hiat1	hippocampus abundant gene transcript 1	0.016
Csk	c-src tyrosine kinase	0.016
Akt1s1	AKT1 substrate 1 (proline-rich)	0.016
Nptn	neuroplastin	0.015
Rhoc	ras homolog gene family, member C	0.015
Spryd3	SPRY domain containing 3	0.015
Fmnl1	formin-like 1	0.015
Rab1b	RAB1B, member RAS oncogene family	0.015
Arrb2	arrestin, beta 2	0.015
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform	0.015
Lin7c	lin-7 homolog C (C. elegans)	0.015
Rab4b	RAB4B, member RAS oncogene family	0.015
Lypla2	lysophospholipase 2	0.015
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.015
Neu3	sialidase 3 (membrane sialidase)	0.015
Ezr	ezrin	0.015
Vasp	vasodilator-stimulated phosphoprotein	0.015
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.014
Commd4	COMM domain containing 4	0.014
Cd37	CD37 molecule	0.014
Actb	actin, beta	0.014
Gng10	guanine nucleotide binding protein (G protein), gamma 10	0.014
Arpc5	actin related protein 2/3 complex, subunit 5	0.014
Gclc	glutamate-cysteine ligase, catalytic subunit	0.014
Porf-2	preoptic regulatory factor-2	0.014
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.014
Bax	Bcl2-associated X protein	0.014
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.014
Bcl10	B-cell CLL/lymphoma 10	0.014
Il17ra	interleukin 17 receptor A	0.014
Tmed2	transmembrane emp24 domain trafficking protein 2	0.013
Sash3	SAM and SH3 domain containing 3	0.013
Nudt16l1	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1	0.013
Eif4e2	eukaryotic translation initiation factor 4E family member 2	0.013
Glg1	golgi apparatus protein 1	0.013
Sec23b	Sec23 homolog B (S. cerevisiae)	0.013
Ly86	lymphocyte antigen 86	0.013
Fam134a	family with sequence similarity 134, member A	0.013
Coq10b	coenzyme Q10 homolog B (S. cerevisiae)	0.013
Plekha6	pleckstrin homology domain containing, family A member 6	0.013
Fam49b	family with sequence similarity 49, member B	0.013
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.013
Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	0.013
Neu2	sialidase 2 (cytosolic sialidase)	0.013
Rab1	RAB1, member RAS oncogene family	0.013
Acsl4	acyl-CoA synthetase long-chain family member 4	0.013
Slfn2	schlafen 2	0.013
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.013
Grb2	growth factor receptor bound protein 2	0.013
Cltc	clathrin, heavy chain (Hc)	0.013
Map2k1	mitogen activated protein kinase kinase 1	0.013
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.012
Kat5	K(lysine) acetyltransferase 5	0.012
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.012
Rogdi	rogdi homolog (Drosophila)	0.012
Suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.012
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.012
Scamp2	secretory carrier membrane protein 2	0.012
Sharpin	SHANK-associated RH domain interactor	0.012
Cdc27	cell division cycle 27 homolog (S. cerevisiae)	0.012
Gak	cyclin G associated kinase	0.012
Dtx3	deltex homolog 3 (Drosophila)	0.012
Stx6	syntaxin 6	0.012
Usp12	ubiquitin specific peptidase 12	0.012
Gdi2	GDP dissociation inhibitor 2	0.012
Cfl1	cofilin 1, non-muscle	0.012
Stx16	syntaxin 16	0.012
Dync1li2	dynein, cytoplasmic 1 light intermediate chain 2	0.012
R3hdm1	R3H domain containing 1	0.012
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.012
Cdk5	cyclin-dependent kinase 5	0.012
Agps	alkylglycerone phosphate synthase	0.012
Exoc5	exocyst complex component 5	0.012
Selt	selenoprotein T	0.011
Sec11a	SEC11 homolog A (S. cerevisiae)	0.011
Ube2i	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.011
Evi2a	ecotropic viral integration site 2A	0.011
Chkb	choline kinase beta	0.011
Ube2z	ubiquitin-conjugating enzyme E2Z	0.011
Scamp1	secretory carrier membrane protein 1	0.011
Cbx6	chromobox homolog 6	0.011
Actg1	actin, gamma 1	0.011
Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)	0.011
Cacnb3	calcium channel, voltage-dependent, beta 3 subunit	0.011
Minpp1	multiple inositol polyphosphate histidine phosphatase 1	0.011
Aurkc	aurora kinase C	0.011
Synj1	synaptojanin 1	0.011
Slc35b2	solute carrier family 35, member B2	0.011
Pitpna	phosphatidylinositol transfer protein, alpha	0.011
Saps2	SAPS domain family, member 2	0.011
Slc35e1	solute carrier family 35, member E1	0.011
Pfkl	phosphofructokinase, liver	0.011
Snapc2	small nuclear RNA activating complex, polypeptide 2	0.011
Mprip	myosin phosphatase Rho interacting protein	0.011
Cd74	Cd74 molecule, major histocompatibility complex, class II invariant chain	0.011
Rlim	ring finger protein, LIM domain interacting	0.010
Arcn1	archain 1	0.010
Btg3	BTG family, member 3	0.010
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.010
Ube2q1	ubiquitin-conjugating enzyme E2Q family member 1	0.010
Arfgap2	ADP-ribosylation factor GTPase activating protein 2	0.010
Pias3	protein inhibitor of activated STAT, 3	0.010
Stk17b	serine/threonine kinase 17b	0.010
Psme2	proteasome (prosome, macropain) activator subunit 2	0.010
Inpp5d	inositol polyphosphate-5-phosphatase D	0.010
Gdi1	GDP dissociation inhibitor 1	0.010
Tusc3	tumor suppressor candidate 3	0.010
Tmx1	thioredoxin-related transmembrane protein 1	0.010