IMP
Process View
arp2 3 complex mediated actin nucleation
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
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Click on a gene's description to view its network relationships with genes known to be involved in "arp2 3 complex mediated actin nucleation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.598 | ||
| Arpc2 | actin related protein 2/3 complex, subunit 2 | 0.459 | ||
| Rap1b | RAP1B, member of RAS oncogene family | 0.330 | ||
| Mapre1 | microtubule-associated protein, RP/EB family, member 1 | 0.323 | ||
| Pfn1 | profilin 1 | 0.321 | ||
| Serp1 | stress-associated endoplasmic reticulum protein 1 | 0.306 | ||
| Gnb2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.195 | ||
| Cap1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.160 | ||
| Atp6v1b2 | ATPase, H transporting, lysosomal V1 subunit B2 | 0.152 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.148 | ||
| Morf4l2 | mortality factor 4 like 2 | 0.121 | ||
| Arpc5 | actin related protein 2/3 complex, subunit 5 | 0.121 | ||
| Pafah1b2 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 | 0.114 | ||
| Efhd2 | EF-hand domain family, member D2 | 0.111 | ||
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform | 0.100 | ||
| Clic1 | chloride intracellular channel 1 | 0.070 | ||
| Coro1a | coronin, actin binding protein 1A | 0.069 | Yeast | |
| Tpm3 | tropomyosin 3, gamma | 0.067 | ||
| Arpc1b | actin related protein 2/3 complex, subunit 1B | 0.065 | Human | |
| Ptma | prothymosin alpha | 0.065 | ||
| Wdr1 | WD repeat domain 1 | 0.064 | ||
| Lcp1 | lymphocyte cytosolic protein 1 | 0.056 | ||
| Prkar1a | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.056 | ||
| Bax | Bcl2-associated X protein | 0.051 | ||
| Atp2b1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.050 | ||
| Tmed2 | transmembrane emp24 domain trafficking protein 2 | 0.049 | ||
| Gria2 | glutamate receptor, ionotropic, AMPA 2 | 0.049 | ||
| Limd2 | LIM domain containing 2 | 0.048 | ||
| Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.043 | Human Yeast | |
| Dbnl | drebrin-like | 0.042 | ||
| RT1-DMa | RT1 class II, locus DMa | 0.041 | ||
| Copb1 | coatomer protein complex, subunit beta 1 | 0.041 | ||
| Psmb10 | proteasome (prosome, macropain) subunit, beta type 10 | 0.038 | ||
| Atp6v1a | ATPase, H+ transporting, lysosomal V1 subunit A | 0.036 | ||
| Map2k1 | mitogen activated protein kinase kinase 1 | 0.035 | ||
| Nsf | N-ethylmaleimide-sensitive factor | 0.035 | ||
| Ap1s1 | adaptor-related protein complex 1, sigma 1 subunit | 0.032 | ||
| Gdi2 | GDP dissociation inhibitor 2 | 0.030 | ||
| Rab6a | RAB6A, member RAS oncogene family | 0.029 | ||
| Arcn1 | archain 1 | 0.029 | ||
| RT1-DMb | RT1 class II, locus DMb | 0.029 | ||
| Lgals3 | lectin, galactoside-binding, soluble, 3 | 0.028 | ||
| Pcnxl3 | pecanex-like 3 (Drosophila) | 0.028 | ||
| Aldh16a1 | aldehyde dehydrogenase 16 family, member A1 | 0.027 | ||
| Laptm5 | lysosomal protein transmembrane 5 | 0.026 | ||
| Coro1b | coronin, actin-binding protein, 1B | 0.026 | Human Yeast | |
| Dgkz | diacylglycerol kinase zeta | 0.025 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.024 | ||
| Usf1 | upstream transcription factor 1 | 0.024 | ||
| Sri | sorcin | 0.024 | ||
| Hnrnpab | heterogeneous nuclear ribonucleoprotein A/B | 0.024 | ||
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.024 | ||
| Scamp2 | secretory carrier membrane protein 2 | 0.024 | ||
| Rhoa | ras homolog gene family, member A | 0.023 | ||
| Arhgdib | Rho, GDP dissociation inhibitor (GDI) beta | 0.023 | ||
| Rnf4 | ring finger protein 4 | 0.023 | ||
| Actg1 | actin, gamma 1 | 0.022 | ||
| S100a10 | S100 calcium binding protein A10 | 0.022 | ||
| Rab2a | RAB2A, member RAS oncogene family | 0.022 | ||
| Ywhaq | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.021 | ||
| Pdia4 | protein disulfide isomerase family A, member 4 | 0.021 | ||
| Cdc27 | cell division cycle 27 homolog (S. cerevisiae) | 0.021 | ||
| Rhoc | ras homolog gene family, member C | 0.021 | ||
| Sec13 | SEC13 homolog (S. cerevisiae) | 0.020 | ||
| Commd4 | COMM domain containing 4 | 0.020 | ||
| Hk1 | hexokinase 1 | 0.020 | ||
| Necap2 | NECAP endocytosis associated 2 | 0.020 | ||
| Erp29 | endoplasmic reticulum protein 29 | 0.020 | ||
| Cotl1 | coactosin-like 1 (Dictyostelium) | 0.019 | ||
| Cttn | cortactin | 0.019 | ||
| Tmbim6 | transmembrane BAX inhibitor motif containing 6 | 0.019 | ||
| Mospd3 | motile sperm domain containing 3 | 0.019 | ||
| Gtf3c1 | general transcription factor IIIC, polypeptide 1, alpha | 0.018 | ||
| Tes | testis derived transcript | 0.018 | ||
| Far1 | fatty acyl CoA reductase 1 | 0.018 | ||
| Sec11a | SEC11 homolog A (S. cerevisiae) | 0.018 | ||
| Cd82 | Cd82 molecule | 0.018 | ||
| Ppp2cb | protein phosphatase 2, catalytic subunit, beta isoform | 0.018 | ||
| Eif4e | eukaryotic translation initiation factor 4E | 0.017 | ||
| Akt1 | v-akt murine thymoma viral oncogene homolog 1 | 0.017 | ||
| Pycard | PYD and CARD domain containing | 0.017 | ||
| Actb | actin, beta | 0.017 | ||
| Agps | alkylglycerone phosphate synthase | 0.017 | ||
| Hspa5 | heat shock protein 5 | 0.017 | ||
| Arfgap2 | ADP-ribosylation factor GTPase activating protein 2 | 0.017 | ||
| Ap2b1 | adaptor-related protein complex 2, beta 1 subunit | 0.017 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.017 | ||
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.017 | ||
| Pik3r2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.016 | ||
| Nptn | neuroplastin | 0.016 | ||
| Odc1 | ornithine decarboxylase 1 | 0.016 | ||
| Sharpin | SHANK-associated RH domain interactor | 0.016 | ||
| Pctk1 | PCTAIRE protein kinase 1 | 0.016 | ||
| Myh10 | myosin, heavy chain 10, non-muscle | 0.016 | ||
| Rapgef2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.016 | ||
| Azin1 | antizyme inhibitor 1 | 0.016 | ||
| Ppp4c | protein phosphatase 4, catalytic subunit | 0.016 | ||
| Uso1 | USO1 homolog, vesicle docking protein (yeast) | 0.015 | ||
| Rgs10 | regulator of G-protein signaling 10 | 0.015 | ||
| Ykt6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.015 | ||
| Sh3gl1 | SH3-domain GRB2-like 1 | 0.015 | ||
| Usp12 | ubiquitin specific peptidase 12 | 0.015 | ||
| Plac8 | placenta-specific 8 | 0.015 | ||
| Synj1 | synaptojanin 1 | 0.015 | ||
| Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform | 0.015 | ||
| Hnrnpk | heterogeneous nuclear ribonucleoprotein K | 0.014 | ||
| Cfl1 | cofilin 1, non-muscle | 0.014 | ||
| Scamp1 | secretory carrier membrane protein 1 | 0.014 | ||
| Tmsb10 | thymosin, beta 10 | 0.014 | ||
| Socs5 | suppressor of cytokine signaling 5 | 0.014 | ||
| Calr | calreticulin | 0.014 | ||
| Spint2 | serine peptidase inhibitor, Kunitz type, 2 | 0.014 | ||
| Pds5a | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) | 0.014 | ||
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.014 | ||
| Ppp2ca | protein phosphatase 2, catalytic subunit, alpha isoform | 0.014 | ||
| Eif4h | eukaryotic translation initiation factor 4H | 0.014 | ||
| Prkcb | protein kinase C, beta | 0.014 | ||
| Pcgf3 | polycomb group ring finger 3 | 0.013 | ||
| Nhp2l1 | NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) | 0.013 | ||
| Rab3gap2 | RAB3 GTPase activating protein subunit 2 | 0.013 | ||
| Ube2d3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.013 | ||
| Grb2 | growth factor receptor bound protein 2 | 0.013 | ||
| Exoc5 | exocyst complex component 5 | 0.013 | ||
| Dnajc5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.013 | ||
| Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.013 | ||
| Arf6 | ADP-ribosylation factor 6 | 0.013 | Rat | |
| Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.013 | ||
| Sat1 | spermidine/spermine N1-acetyl transferase 1 | 0.012 | ||
| Stk17b | serine/threonine kinase 17b | 0.012 | ||
| Npap60 | nuclear pore associated protein | 0.012 | ||
| Ifrd1 | interferon-related developmental regulator 1 | 0.012 | ||
| Pak2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.012 | ||
| Tssc4 | tumor suppressing subtransferable candidate 4 | 0.012 | ||
| RGD1307254 | similar to RIKEN cDNA 1200011I18 | 0.012 | ||
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.012 | ||
| Ywhah | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.012 | ||
| Txnrd1 | thioredoxin reductase 1 | 0.012 | ||
| Mare | alpha globin regulatory element containing gene | 0.012 | ||
| Sec61a1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.012 | ||
| Porf-2 | preoptic regulatory factor-2 | 0.012 | ||
| Ahcyl1 | adenosylhomocysteinase-like 1 | 0.012 | ||
| Lcp2 | lymphocyte cytosolic protein 2 | 0.012 | ||
| Dstn | destrin | 0.012 | ||
| Gdi1 | GDP dissociation inhibitor 1 | 0.012 | ||
| Cyfip2 | cytoplasmic FMR1 interacting protein 2 | 0.012 | ||
| Ube2z | ubiquitin-conjugating enzyme E2Z | 0.011 | ||
| Ppp2r4 | protein phosphatase 2A activator, regulatory subunit 4 | 0.011 | ||
| Bet1l | blocked early in transport 1 homolog (S. cerevisiae) like | 0.011 | ||
| Spryd3 | SPRY domain containing 3 | 0.011 | ||
| Tmx1 | thioredoxin-related transmembrane protein 1 | 0.011 | ||
| Rab8b | RAB8B, member RAS oncogene family | 0.011 | ||
| Litaf | lipopolysaccharide-induced TNF factor | 0.011 | ||
| Dnm1l | dynamin 1-like | 0.011 | ||
| RGD1311122 | similar to RIKEN cDNA 1110003E01 | 0.011 | ||
| Gls | glutaminase | 0.011 | ||
| Gng10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.011 | ||
| Prr13 | proline rich 13 | 0.011 | ||
| Arf5 | ADP-ribosylation factor 5 | 0.011 | Rat | |
| Crlf3 | cytokine receptor-like factor 3 | 0.011 | ||
| Olfm1 | olfactomedin 1 | 0.011 | ||
| Scd | stearoyl-CoA desaturase (delta-9-desaturase) | 0.011 | ||
| Ap3s1 | adaptor-related protein complex 3, sigma 1 subunit | 0.011 | ||
| Tle2 | transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) | 0.011 | ||
| Crmp1 | collapsin response mediator protein 1 | 0.011 | ||
| Neu3 | sialidase 3 (membrane sialidase) | 0.011 | ||
| Cltc | clathrin, heavy chain (Hc) | 0.011 | ||
| Aprt | adenine phosphoribosyl transferase | 0.011 | ||
| Arrb2 | arrestin, beta 2 | 0.011 | ||
| Klf6 | Kruppel-like factor 6 | 0.011 | ||
| Suv420h2 | suppressor of variegation 4-20 homolog 2 (Drosophila) | 0.011 | ||
| Elovl5 | ELOVL family member 5, elongation of long chain fatty acids (yeast) | 0.011 | ||
| Slc30a4 | solute carrier family 30 (zinc transporter), member 4 | 0.011 | ||
| Slc4a3 | solute carrier family 4 (anion exchanger), member 3 | 0.010 | ||
| Lin7c | lin-7 homolog C (C. elegans) | 0.010 | ||
| Freq | frequenin homolog (Drosophila) | 0.010 | ||
| Alg2 | asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) | 0.010 | ||
| Cdc42se2 | CDC42 small effector 2 | 0.010 | ||
| Dcaf7 | DDB1 and CUL4 associated factor 7 | 0.010 | ||
| B3gat3 | beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) | 0.010 | ||
| Capg | capping protein (actin filament), gelsolin-like | 0.010 | ||
| Sdcbp | syndecan binding protein | 0.010 | ||
| Lman1 | lectin, mannose-binding, 1 | 0.010 | ||
| Cnp | 2',3'-cyclic nucleotide 3' phosphodiesterase | 0.010 | ||
| Cdk5 | cyclin-dependent kinase 5 | 0.010 |