IMP
Process View
dendritic spine development
The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "dendritic spine development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Pfn1 | profilin 1 | 0.735 | ||
| Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.275 | ||
| Morf4l2 | mortality factor 4 like 2 | 0.236 | ||
| Gnb2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.215 | ||
| Pafah1b2 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 | 0.089 | ||
| Dlgap3 | discs, large (Drosophila) homolog-associated protein 3 | 0.083 | ||
| Wdr1 | WD repeat domain 1 | 0.076 | ||
| Magi2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.071 | ||
| Gria2 | glutamate receptor, ionotropic, AMPA 2 | 0.055 | ||
| Gria1 | glutamate receptor, ionotropic, AMPA 1 | 0.047 | ||
| Prkacb | protein kinase, cAMP dependent, catalytic, beta | 0.042 | ||
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.042 | ||
| Dlg2 | discs, large homolog 2 (Drosophila) | 0.041 | Rat | |
| Cnksr2 | connector enhancer of kinase suppressor of Ras 2 | 0.040 | ||
| Slc1a1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.040 | ||
| Rab4b | RAB4B, member RAS oncogene family | 0.037 | ||
| Dlg3 | discs, large homolog 3 (Drosophila) | 0.036 | Rat | |
| Prelid1 | PRELI domain containing 1 | 0.035 | ||
| Nsf | N-ethylmaleimide-sensitive factor | 0.030 | ||
| Grin2b | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.029 | ||
| Arhgef7 | Rho guanine nucleotide exchange factor (GEF7) | 0.028 | ||
| Rab15 | RAB15, member RAS oncogene family | 0.027 | ||
| Nrxn1 | neurexin 1 | 0.027 | ||
| Ctsb | cathepsin B | 0.027 | ||
| Sh3gl2 | SH3-domain GRB2-like 2 | 0.026 | ||
| Cltc | clathrin, heavy chain (Hc) | 0.026 | ||
| PVR | poliovirus receptor | 0.026 | ||
| Nr4a2 | nuclear receptor subfamily 4, group A, member 2 | 0.023 | ||
| Prkca | protein kinase C, alpha | 0.023 | ||
| Nlgn1 | neuroligin 1 | 0.022 | ||
| Sdk2 | sidekick homolog 2 (chicken) | 0.022 | ||
| Mos | Moloney sarcoma oncogene | 0.022 | ||
| Syt4 | synaptotagmin IV | 0.022 | ||
| Mybpc1 | myosin binding protein C, slow type | 0.021 | ||
| Map2 | microtubule-associated protein 2 | 0.020 | ||
| LOC683751 | similar to trophinin isoform 1 | 0.020 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.020 | ||
| Actb | actin, beta | 0.020 | ||
| Ppp1r9a | protein phosphatase 1, regulatory (inhibitor) subunit 9A | 0.020 | ||
| Prkcb | protein kinase C, beta | 0.019 | ||
| RGD1311122 | similar to RIKEN cDNA 1110003E01 | 0.018 | ||
| Epha5 | EphA5 | 0.018 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.018 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.018 | ||
| Vat1 | vesicle amine transport protein 1 homolog (T californica) | 0.017 | ||
| Dlgap2 | discs, large (Drosophila) homolog-associated protein 2 | 0.017 | ||
| Kcnab2 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 0.017 | ||
| Nrcam | neuronal cell adhesion molecule | 0.016 | ||
| Nlgn2 | neuroligin 2 | 0.016 | Rat | |
| Syt12 | synaptotagmin XII | 0.015 | ||
| Grm5 | glutamate receptor, metabotropic 5 | 0.015 | ||
| Gabrb3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 0.015 | ||
| Ryr2 | ryanodine receptor 2, cardiac | 0.015 | ||
| Baiap2 | BAI1-associated protein 2 | 0.015 | ||
| Homer1 | homer homolog 1 (Drosophila) | 0.015 | ||
| Cask | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.014 | ||
| Sipa1l1 | signal-induced proliferation-associated 1 like 1 | 0.014 | ||
| Dgki | diacylglycerol kinase, iota | 0.014 | ||
| Grip1 | glutamate receptor interacting protein 1 | 0.014 | ||
| Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.014 | ||
| LOC100360165 | rCG29588-like | 0.014 | ||
| Ctsh | cathepsin H | 0.014 | ||
| Unc5a | unc-5 homolog A (C. elegans) | 0.014 | ||
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.014 | ||
| Kcnab1 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 0.014 | ||
| Cttn | cortactin | 0.014 | ||
| Tpm3 | tropomyosin 3, gamma | 0.013 | ||
| Rabac1 | Rab acceptor 1 (prenylated) | 0.013 | ||
| Atf2 | activating transcription factor 2 | 0.013 | ||
| Apc | adenomatous polyposis coli | 0.013 | ||
| LOC100360986 | mCG1035404-like | 0.013 | ||
| Gabra5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 | 0.013 | ||
| Shank2 | SH3 and multiple ankyrin repeat domains 2 | 0.013 | Rat | |
| Trhde | thyrotropin-releasing hormone degrading enzyme | 0.013 | ||
| Akt3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 0.013 | ||
| Ttpa | tocopherol (alpha) transfer protein | 0.013 | ||
| Hapln1 | hyaluronan and proteoglycan link protein 1 | 0.013 | ||
| Actg1 | actin, gamma 1 | 0.013 | ||
| Atp6v1b2 | ATPase, H transporting, lysosomal V1 subunit B2 | 0.013 | ||
| Rasgrp1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.013 | ||
| Met | met proto-oncogene | 0.012 | ||
| Fkbp1a | FK506 binding protein 1a | 0.012 | ||
| Gabra1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 0.012 | ||
| Bsn | bassoon | 0.012 | ||
| Sstr2 | somatostatin receptor 2 | 0.012 | ||
| Calr | calreticulin | 0.012 | ||
| Mllt4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.012 | ||
| Azin1 | antizyme inhibitor 1 | 0.012 | ||
| Lphn1 | latrophilin 1 | 0.012 | ||
| Sp4 | Sp4 transcription factor | 0.011 | ||
| Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.011 | ||
| Olr1226 | olfactory receptor 1226 | 0.011 | ||
| Irf1 | interferon regulatory factor 1 | 0.011 | ||
| Cnr1 | cannabinoid receptor 1 (brain) | 0.011 | Rat | |
| Gabra2 | gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2 | 0.011 | ||
| Lin7b | lin-7 homolog b (C. elegans) | 0.011 | ||
| Ctnnd2 | catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) | 0.011 | ||
| Otub1 | OTU domain, ubiquitin aldehyde binding 1 | 0.011 | ||
| Kif3c | kinesin family member 3C | 0.011 | ||
| Crygb | crystallin, gamma B | 0.011 | ||
| Atp6v0c | ATPase, H+ transporting, lysosomal V0 subunit C | 0.011 | ||
| Tmbim6 | transmembrane BAX inhibitor motif containing 6 | 0.011 | ||
| Grm8 | glutamate receptor, metabotropic 8 | 0.011 | ||
| Tmod2 | tropomodulin 2 | 0.010 | ||
| Drd1a | dopamine receptor D1A | 0.010 | ||
| Nr4a3 | nuclear receptor subfamily 4, group A, member 3 | 0.010 | ||
| Cugbp2 | CUG triplet repeat, RNA binding protein 2 | 0.010 | ||
| Shank1 | SH3 and multiple ankyrin repeat domains 1 | 0.010 | ||
| Mmp16 | matrix metallopeptidase 16 | 0.010 | ||
| Itpka | inositol 1,4,5-trisphosphate 3-kinase A | 0.010 | ||
| Nudt16l1 | nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 | 0.010 | ||
| Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.010 | ||
| Robo2 | roundabout homolog 2 (Drosophila) | 0.010 | ||
| Epb41l3 | erythrocyte membrane protein band 4.1-like 3 | 0.010 | ||
| Abi1 | abl-interactor 1 | 0.010 | ||
| Ptov1 | prostate tumor overexpressed 1 | 0.010 | ||
| Senp2 | Sumo1/sentrin/SMT3 specific peptidase 2 | 0.010 |