IMP

Process View

Saccharomyces cerevisiae

20 genes annotated in yeast

protein import into mitochondrial matrix

The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.

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In addition to gene-name show these genes:

Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein import into mitochondrial matrix"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein import into mitochondrial matrix" (in gray)

Name	Description	Probability
TIM23	Tim23p	1.000
TIM17	Tim17p	1.000
TIM44	Tim44p	1.000
TOM22	Tom22p	1.000
PAM18	Pam18p	1.000
TIM50	Tim50p	0.996
TOM40	Tom40p	0.993
TOM20	Tom20p	0.990
SSC1	Ssc1p	0.953
TOM7	Tom7p	0.877
TOM5	Tom5p	0.859
TOM70	Tom70p	0.828
PAM16	Pam16p	0.705
TOM6	Tom6p	0.488
SAM35	Sam35p	0.327
MGE1	Mge1p	0.156
TIM10	Tim10p	0.153
CUR1	Cur1p	0.105
BTN2	Btn2p	0.072
MIC17	Mic17p	0.069
LHS1	Lhs1p	0.065
SIS1	Sis1p	0.053
TIM21	Tim21p	0.050
MGR2	Mgr2p	0.050
TIM8	Tim8p	0.045
ALT2	Alt2p	0.043
GRX5	Grx5p	0.039
SRD1	Srd1p	0.038
UGO1	Ugo1p	0.038
YLR264C-A	hypothetical protein	0.033
LEU2	Leu2p	0.032
KAR2	Kar2p	0.026
CLU1	Clu1p	0.026
JEM1	Jem1p	0.025
YOL038C-A	hypothetical protein	0.025
TIM22	Tim22p	0.025
ARP10	Arp10p	0.025
YLR162W	hypothetical protein	0.025
TIM18	Tim18p	0.025
STI1	Sti1p	0.024
HOR2	Hor2p	0.023
MER1	Mer1p	0.021
UPS3	Ups3p	0.021
TOA2	Toa2p	0.021
YLR042C	hypothetical protein	0.020
HXT3	Hxt3p	0.020
MTG1	Mtg1p	0.019
ACP1	Acp1p	0.019
NTA1	Nta1p	0.019
ATP6	Atp6p	0.019
YAR068W	hypothetical protein	0.018
YBR013C	hypothetical protein	0.018
CUP1-1	Cup1-1p	0.018
YPR157W	hypothetical protein	0.018
ARG8	Arg8p	0.018
CHA1	Cha1p	0.018
AIM1	Aim1p	0.018
FMT1	Fmt1p	0.018
RDL2	Rdl2p	0.018
YKR075C	hypothetical protein	0.018
GTO1	Gto1p	0.017
ZPS1	Zps1p	0.017
YOL013W-A	hypothetical protein	0.017
RTC6	Rtc6p	0.017
SPL2	Spl2p	0.017
TYE7	Tye7p	0.017
CPD1	Cpd1p	0.016
YML003W	hypothetical protein	0.016
SOV1	Sov1p	0.016
YJL181W	hypothetical protein	0.016
AUA1	Aua1p	0.016
HPF1	Hpf1p	0.016
SWC7	Swc7p	0.015
ADH2	Adh2p	0.015
RTT105	Rtt105p	0.015
AQY2	Aqy2p	0.015
REE1	Ree1p	0.014
OPT2	Opt2p	0.014
DIC1	Dic1p	0.014
YIR035C	hypothetical protein	0.014
DIF1	Dif1p	0.014
ARO10	Aro10p	0.014
LCB4	Lcb4p	0.014
BSC1	Bsc1p	0.014
YIL151C	hypothetical protein	0.014
LCL2	Lcl2p	0.014
HEM12	Hem12p	0.014
HO	Hop	0.014
MF(ALPHA)2	Mf(alpha)2p	0.014
BNA4	Bna4p	0.013
MRPL50	Mrpl50p	0.013
YAH1	Yah1p	0.013
IZH4	Izh4p	0.013
TFC7	Tfc7p	0.013
YAR066W	hypothetical protein	0.013
RNP1	Rnp1p	0.013
YNL018C	hypothetical protein	0.013
MRPL20	Mrpl20p	0.013
YLL053C	hypothetical protein	0.013
DUR1,2	Dur1,2p	0.013
SSP1	Ssp1p	0.013
NRG2	Nrg2p	0.013
PCL1	Pcl1p	0.012
YJL213W	hypothetical protein	0.012
YER064C	hypothetical protein	0.012
YJR120W	hypothetical protein	0.012
AAD6	Aad6p	0.012
YIR042C	hypothetical protein	0.012
URA3	Ura3p	0.012
MFA2	Mfa2p	0.012
YAL037C-A	hypothetical protein	0.012
YLR126C	hypothetical protein	0.012
GYL1	Gyl1p	0.012
YPR096C	hypothetical protein	0.012
YDR186C	hypothetical protein	0.012
COS12	Cos12p	0.011
ARR2	Arr2p	0.011
SRX1	Srx1p	0.011
CUE4	Cue4p	0.011
KNH1	Knh1p	0.011
YAL064W	hypothetical protein	0.011
SRT1	Srt1p	0.011
YMR317W	hypothetical protein	0.011
YNL067W-B	hypothetical protein	0.011
AAD15	Aad15p	0.011
SCM4	Scm4p	0.011
MET8	Met8p	0.011
YPL067C	hypothetical protein	0.011
PTR2	Ptr2p	0.011
RRN5	Rrn5p	0.010
YCH1	Ych1p	0.010
YLR040C	hypothetical protein	0.010
LCL1	Lcl1p	0.010
CAB4	Cab4p	0.010
SFT1	Sft1p	0.010
BDS1	Bds1p	0.010
YJL218W	hypothetical protein	0.010