IMP

Process View

Saccharomyces cerevisiae

26 genes annotated in yeast

gpi anchor biosynthetic process

The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gpi anchor biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "gpi anchor biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
LAS21	Las21p	0.984
GAB1	Gab1p	0.976
GWT1	Gwt1p	0.793
GPI17	Gpi17p	0.771
ALG6	Alg6p	0.672
GPI2	Gpi2p	0.635
GAA1	Gaa1p	0.590
PER1	Per1p	0.585
GPI16	Gpi16p	0.392
YJR015W	hypothetical protein	0.378
GPI8	Gpi8p	0.349
SFB3	Sfb3p	0.151
MCD4	Mcd4p	0.144
ERD2	Erd2p	0.133
GPI11	Gpi11p	0.105
SEC24	Sec24p	0.101
GPI13	Gpi13p	0.096
CNE1	Cne1p	0.093
GUP1	Gup1p	0.085
YLR036C	hypothetical protein	0.084
ARV1	Arv1p	0.078
SPF1	Spf1p	0.077
SEC59	Sec59p	0.072
CHS7	Chs7p	0.071
YJR012C	hypothetical protein	0.068
RFT1	Rft1p	0.064
ALG12	Alg12p	0.061
PMT3	Pmt3p	0.061
ELO1	Elo1p	0.060
SED4	Sed4p	0.057
GPI1	Gpi1p	0.056
GPI19	Gpi19p	0.056
YGL140C	hypothetical protein	0.051
VBA2	Vba2p	0.049
SRD1	Srd1p	0.048
BST1	Bst1p	0.047
YAR068W	hypothetical protein	0.044
DIE2	Die2p	0.044
YER186C	hypothetical protein	0.042
SFT1	Sft1p	0.041
ISC1	Isc1p	0.040
YOL038C-A	hypothetical protein	0.039
CUP1-1	Cup1-1p	0.039
OSH7	Osh7p	0.039
TAD2	Tad2p	0.037
YAR066W	hypothetical protein	0.037
SEC31	Sec31p	0.036
YLR264C-A	hypothetical protein	0.036
ARP10	Arp10p	0.036
YNR061C	hypothetical protein	0.036
YLR162W	hypothetical protein	0.036
LEU2	Leu2p	0.034
PFA4	Pfa4p	0.034
RRN5	Rrn5p	0.034
NHX1	Nhx1p	0.034
YLR042C	hypothetical protein	0.033
MER1	Mer1p	0.033
TSC3	Tsc3p	0.033
BET3	Bet3p	0.031
FMT1	Fmt1p	0.031
LHS1	Lhs1p	0.031
MST27	Mst27p	0.030
PRS2	Prs2p	0.029
YPR153W	hypothetical protein	0.029
ZPS1	Zps1p	0.029
OPT2	Opt2p	0.029
ATP6	Atp6p	0.029
AUA1	Aua1p	0.029
YPR157W	hypothetical protein	0.028
SPL2	Spl2p	0.028
ARO10	Aro10p	0.028
SCS7	Scs7p	0.028
ROT2	Rot2p	0.028
YCH1	Ych1p	0.027
YLR040C	hypothetical protein	0.027
YSC83	Ysc83p	0.027
CPD1	Cpd1p	0.027
SMF3	Smf3p	0.026
HPF1	Hpf1p	0.026
YCR023C	hypothetical protein	0.026
OSM1	Osm1p	0.026
MF(ALPHA)2	Mf(alpha)2p	0.026
ARG8	Arg8p	0.026
YBR013C	hypothetical protein	0.026
YLR126C	hypothetical protein	0.026
BNA4	Bna4p	0.026
NRG2	Nrg2p	0.026
YHR177W	hypothetical protein	0.026
YJL181W	hypothetical protein	0.026
ERV15	Erv15p	0.026
YHL017W	hypothetical protein	0.025
VBA1	Vba1p	0.025
AXL2	Axl2p	0.025
BSC1	Bsc1p	0.025
QNS1	Qns1p	0.025
YOL013W-A	hypothetical protein	0.025
BDS1	Bds1p	0.025
CWH43	Cwh43p	0.025
ALT2	Alt2p	0.025
PAD1	Pad1p	0.024
YLR132C	hypothetical protein	0.024
BIG1	Big1p	0.024
COS12	Cos12p	0.024
VBA5	Vba5p	0.023
YAL037C-A	hypothetical protein	0.023
ALG11	Alg11p	0.023
YML003W	hypothetical protein	0.023
RNR2	Rnr2p	0.023
RTS2	Rts2p	0.023
YKR075C	hypothetical protein	0.023
DFG10	Dfg10p	0.022
SSP1	Ssp1p	0.022
YDR222W	hypothetical protein	0.022
DSE4	Dse4p	0.022
YBL044W	hypothetical protein	0.022
YHK8	Yhk8p	0.022
SPT14	Spt14p	0.022
YOR385W	hypothetical protein	0.022
SMP3	Smp3p	0.022
DIA1	Dia1p	0.022
KRE2	Kre2p	0.022
YPR071W	hypothetical protein	0.022
CAB2	Cab2p	0.022
YNL040W	hypothetical protein	0.021
TIR3	Tir3p	0.021
YJL218W	hypothetical protein	0.021
YJR120W	hypothetical protein	0.021
UPS3	Ups3p	0.021
BET2	Bet2p	0.021
YEA6	Yea6p	0.021
APD1	Apd1p	0.021
GPI14	Gpi14p	0.021
SWC7	Swc7p	0.021
YIR042C	hypothetical protein	0.021
PGS1	Pgs1p	0.021
CHA1	Cha1p	0.021
YNR062C	hypothetical protein	0.021
TRS23	Trs23p	0.021
KTR2	Ktr2p	0.020
REE1	Ree1p	0.020
SPS4	Sps4p	0.020
YIR035C	hypothetical protein	0.020
ERI1	Eri1p	0.020
RTT105	Rtt105p	0.020
PMT5	Pmt5p	0.020
ICS3	Ics3p	0.020
FRE8	Fre8p	0.020
YNL033W	hypothetical protein	0.020
YAL064W	hypothetical protein	0.019
RNP1	Rnp1p	0.019
AGP1	Agp1p	0.019
DIC1	Dic1p	0.019
AQY2	Aqy2p	0.019
ICS2	Ics2p	0.019
YJL160C	hypothetical protein	0.019
AVT2	Avt2p	0.019
HMRA1	Hmra1p	0.019
RDS3	Rds3p	0.019
YOR302W	hypothetical protein	0.019
LCL1	Lcl1p	0.019
SCM4	Scm4p	0.019
YGL006W-A	hypothetical protein	0.018
NEO1	Neo1p	0.018
HEM3	Hem3p	0.018
YBL029W	hypothetical protein	0.018
YPR027C	hypothetical protein	0.018
RRT5	Rrt5p	0.018
MF(ALPHA)1	Mf(alpha)1p	0.018
SET4	Set4p	0.018
MDJ2	Mdj2p	0.018
LRE1	Lre1p	0.018
YMR317W	hypothetical protein	0.018
ARR2	Arr2p	0.018
YOR387C	hypothetical protein	0.018
CUP1-2	Cup1-2p	0.018
DCG1	Dcg1p	0.018
YPR096C	hypothetical protein	0.018
CAB1	Cab1p	0.018
YKL063C	hypothetical protein	0.018
CTR3	Ctr3p	0.018
KSH1	Ksh1p	0.017
AAD15	Aad15p	0.017
AAD6	Aad6p	0.017
YOR012W	hypothetical protein	0.017
KRE29	Kre29p	0.017
ERT1	Ert1p	0.017
SCT1	Sct1p	0.017
YAL018C	hypothetical protein	0.017
MFA2	Mfa2p	0.017
YNL018C	hypothetical protein	0.017
ECM9	Ecm9p	0.017
PDR3	Pdr3p	0.017
SEO1	Seo1p	0.017
YNL067W-B	hypothetical protein	0.017
YLR412C-A	hypothetical protein	0.017
YKR041W	hypothetical protein	0.017
YMR122W-A	hypothetical protein	0.017
YBP1	Ybp1p	0.017
YPL162C	hypothetical protein	0.017
OLE1	Ole1p	0.017
YER187W	hypothetical protein	0.017
AVT5	Avt5p	0.017
YNL058C	hypothetical protein	0.017
YOR060C	hypothetical protein	0.017
PFA3	Pfa3p	0.016
YPL067C	hypothetical protein	0.016
DUR1,2	Dur1,2p	0.016
YNL034W	hypothetical protein	0.016
STE3	Ste3p	0.016
HEM12	Hem12p	0.016
FCY22	Fcy22p	0.016
UBC12	Ubc12p	0.016
LUC7	Luc7p	0.016
BIO4	Bio4p	0.016
YPR159C-A	hypothetical protein	0.016
LIF1	Lif1p	0.016
YVC1	Yvc1p	0.016
POR2	Por2p	0.016
YGR126W	hypothetical protein	0.016
CHA4	Cha4p	0.016
YDR524W-C	hypothetical protein	0.016
BIO5	Bio5p	0.016
ZRT1	Zrt1p	0.016
HXT3	Hxt3p	0.016
YOR365C	hypothetical protein	0.016
ORC5	Orc5p	0.016
PDR8	Pdr8p	0.016
COS10	Cos10p	0.016
ADH2	Adh2p	0.016
YBL086C	hypothetical protein	0.016
IPT1	Ipt1p	0.016
HRT3	Hrt3p	0.016
IZH4	Izh4p	0.016
YBR219C	hypothetical protein	0.016
CAR1	Car1p	0.016
TGL1	Tgl1p	0.015
BAT2	Bat2p	0.015
YER175W-A	hypothetical protein	0.015
DIF1	Dif1p	0.015
YML100W-A	hypothetical protein	0.015
YCL001W-B	hypothetical protein	0.015
YGL235W	hypothetical protein	0.015
SPO74	Spo74p	0.015
PTR2	Ptr2p	0.015
YJL107C	hypothetical protein	0.015
YLR342W-A	hypothetical protein	0.015
YAL037W	hypothetical protein	0.015
YAR029W	hypothetical protein	0.015
FRE4	Fre4p	0.015
RMD6	Rmd6p	0.015
URA3	Ura3p	0.015
MET8	Met8p	0.015
YUR1	Yur1p	0.015
YDR132C	hypothetical protein	0.015
YIL001W	hypothetical protein	0.015
BI4	Bi4p	0.015
ERV2	Erv2p	0.015
YER085C	hypothetical protein	0.015
SNU23	Snu23p	0.015
YHR045W	hypothetical protein	0.015
DOG1	Dog1p	0.015
YCR015C	hypothetical protein	0.015
SAG1	Sag1p	0.015
SAM3	Sam3p	0.015
CAB4	Cab4p	0.015
YMR001C-A	hypothetical protein	0.015
YKL106C-A	hypothetical protein	0.015
LAG1	Lag1p	0.015
HXT11	Hxt11p	0.015
WSC3	Wsc3p	0.014
UTR4	Utr4p	0.014
KNH1	Knh1p	0.014
SSY5	Ssy5p	0.014
YDR034C-A	hypothetical protein	0.014
YPL168W	hypothetical protein	0.014
YIL089W	hypothetical protein	0.014
GCV1	Gcv1p	0.014
YLR460C	hypothetical protein	0.014
GPI10	Gpi10p	0.014
YPR003C	hypothetical protein	0.014
YGL015C	hypothetical protein	0.014
TFC6	Tfc6p	0.014
GPD2	Gpd2p	0.014
YPS3	Yps3p	0.014
YGL082W	hypothetical protein	0.014
CUE2	Cue2p	0.014
YGR015C	hypothetical protein	0.014
CUE4	Cue4p	0.014
PRY3	Pry3p	0.014
YKL070W	hypothetical protein	0.014
MMP1	Mmp1p	0.014
YSR3	Ysr3p	0.014
YGL262W	hypothetical protein	0.014
BTT1	Btt1p	0.014
COS9	Cos9p	0.014
YDR182W-A	hypothetical protein	0.014
LCB3	Lcb3p	0.014
MUM3	Mum3p	0.014
YHR078W	hypothetical protein	0.014
ENA5	Ena5p	0.014
SWM2	Swm2p	0.014
ICP55	Icp55p	0.014
YIL151C	hypothetical protein	0.014
YLL053C	hypothetical protein	0.014
YLR406C-A	hypothetical protein	0.014
UGA4	Uga4p	0.014
YLR125W	hypothetical protein	0.014
TYE7	Tye7p	0.014
YOR316C-A	hypothetical protein	0.014
PUS6	Pus6p	0.014
YDR114C	hypothetical protein	0.014
AIF1	Aif1p	0.014
SRT1	Srt1p	0.014
RAM2	Ram2p	0.014
YMR147W	hypothetical protein	0.013
YCR050C	hypothetical protein	0.013
SRX1	Srx1p	0.013
IMA5	Ima5p	0.013
BIO2	Bio2p	0.013
LDB16	Ldb16p	0.013
TNA1	Tna1p	0.013
PYC2	Pyc2p	0.013
YNL097C-B	hypothetical protein	0.013
ENT4	Ent4p	0.013
SLI1	Sli1p	0.013
ARO9	Aro9p	0.013
ECM22	Ecm22p	0.013
YML053C	hypothetical protein	0.013
CEP3	Cep3p	0.013
MIG2	Mig2p	0.013
YOR268C	hypothetical protein	0.013
RPR2	Rpr2p	0.013
YKL068W-A	hypothetical protein	0.013
YOL097W-A	hypothetical protein	0.013
PHO8	Pho8p	0.013
SGE1	Sge1p	0.013
CAN1	Can1p	0.013
YNL162W-A	hypothetical protein	0.013
YJL213W	hypothetical protein	0.013
YIL046W-A	hypothetical protein	0.013
YLR012C	hypothetical protein	0.013
YJL028W	hypothetical protein	0.013
YNL277W-A	hypothetical protein	0.013
FDC1	Fdc1p	0.013
YCL021W-A	hypothetical protein	0.013
PMA2	Pma2p	0.013
YNL234W	hypothetical protein	0.013
SRO77	Sro77p	0.013
CWP1	Cwp1p	0.013
CSH1	Csh1p	0.013
UBX7	Ubx7p	0.013
PRP18	Prp18p	0.013
YEA4	Yea4p	0.013
BUR6	Bur6p	0.013
WSC4	Wsc4p	0.013
NUT2	Nut2p	0.013
GAS2	Gas2p	0.013
BNA7	Bna7p	0.013
REV7	Rev7p	0.013
BUD8	Bud8p	0.013
FRE7	Fre7p	0.013
MCH5	Mch5p	0.013
SPO19	Spo19p	0.013
YOS1	Yos1p	0.013
YJL047C-A	hypothetical protein	0.013
GEM1	Gem1p	0.013
PRP38	Prp38p	0.013
YOL014W	hypothetical protein	0.013
YLR281C	hypothetical protein	0.012
PPQ1	Ppq1p	0.012
FRE3	Fre3p	0.012
RPI1	Rpi1p	0.012
OLI1	F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2	0.012
CRP1	Crp1p	0.012
YNR063W	hypothetical protein	0.012
SMF2	Smf2p	0.012
YPL152W-A	hypothetical protein	0.012
YOL086W-A	hypothetical protein	0.012
YPR108W-A	hypothetical protein	0.012
YHR035W	hypothetical protein	0.012
EEB1	Eeb1p	0.012
RRI1	Rri1p	0.012
NFT1	Nft1p	0.012
YDR336W	hypothetical protein	0.012
YPR036W-A	hypothetical protein	0.012
SPO77	Spo77p	0.012
BIT61	Bit61p	0.012
HMLALPHA2	Hmlalpha2p	0.012
YNL046W	hypothetical protein	0.012
YJR154W	hypothetical protein	0.012
PHO11	Pho11p	0.012
EDC1	Edc1p	0.012
YGR017W	hypothetical protein	0.012
YFL051C	hypothetical protein	0.012
MDL1	Mdl1p	0.012
YDL133W	hypothetical protein	0.012
ASP3-4	Asp3-4p	0.012
CHO1	Cho1p	0.012
HOL1	Hol1p	0.012
ZRT2	Zrt2p	0.012
ABM1	Abm1p	0.012
ARN2	Arn2p	0.012
MPH3	Mph3p	0.012
PRM4	Prm4p	0.012
YDR042C	hypothetical protein	0.012
YNL146C-A	hypothetical protein	0.012
IMA2	Ima2p	0.012
PTI1	Pti1p	0.012
ERG10	Erg10p	0.012
FIT2	Fit2p	0.012
YER152C	hypothetical protein	0.012
YLR278C	hypothetical protein	0.012
YBR296C-A	hypothetical protein	0.012
SSL1	Ssl1p	0.012
SSU1	Ssu1p	0.012
SCS3	Scs3p	0.012
CWP2	Cwp2p	0.012
ATF1	Atf1p	0.012
YSF3	Ysf3p	0.012
GAP1	Gap1p	0.012
MFA1	Mfa1p	0.012
ECM3	Ecm3p	0.012
YFR035C	hypothetical protein	0.012
GMH1	Gmh1p	0.012
HLJ1	Hlj1p	0.012
YMR272W-B	hypothetical protein	0.012
YHC3	Yhc3p	0.012
HOR2	Hor2p	0.011
YMR279C	hypothetical protein	0.011
RCE1	Rce1p	0.011
YLR307C-A	hypothetical protein	0.011
ENB1	Enb1p	0.011
YHR050W-A	hypothetical protein	0.011
TVP23	Tvp23p	0.011
VPS74	Vps74p	0.011
YLR108C	hypothetical protein	0.011
GCV2	Gcv2p	0.011
BOR1	Bor1p	0.011
NVJ1	Nvj1p	0.011
DAN1	Dan1p	0.011
ACK1	Ack1p	0.011
COX19	Cox19p	0.011
QDR2	Qdr2p	0.011
DAK2	Dak2p	0.011
TPC1	Tpc1p	0.011
DAL7	Dal7p	0.011
FRE5	Fre5p	0.011
YCR102C	hypothetical protein	0.011
PRM10	Prm10p	0.011
YML054C-A	hypothetical protein	0.011
HMRA2	Hmra2p	0.011
YNR066C	hypothetical protein	0.011
YIR021W-A	hypothetical protein	0.011
YHR007C-A	hypothetical protein	0.011
YOR293C-A	hypothetical protein	0.011
TOK1	Tok1p	0.011
YLR363W-A	hypothetical protein	0.011
YDR169C-A	hypothetical protein	0.011
CTR2	Ctr2p	0.011
YJL147C	hypothetical protein	0.011
CDD1	Cdd1p	0.011
RHB1	Rhb1p	0.011
PHA2	Pha2p	0.011
RRT13	Rrt13p	0.011
SEN54	Sen54p	0.011
YLR050C	hypothetical protein	0.011
YIR018C-A	hypothetical protein	0.011
YAL065C	hypothetical protein	0.011
YPL066W	hypothetical protein	0.011
YIL102C	hypothetical protein	0.011
PMT6	Pmt6p	0.011
GYP6	Gyp6p	0.011
VHR1	Vhr1p	0.011
BRN1	Brn1p	0.011
YPR063C	hypothetical protein	0.011
ATR1	Atr1p	0.011
YML007C-A	hypothetical protein	0.011
YJR116W	hypothetical protein	0.011
AZR1	Azr1p	0.011
FRM2	Frm2p	0.011
YGR169C-A	hypothetical protein	0.011
PHO12	Pho12p	0.011
SKS1	Sks1p	0.010
HES1	Hes1p	0.010
YOR338W	hypothetical protein	0.010
SAY1	Say1p	0.010
HXT8	Hxt8p	0.010
MATALPHA1	Matalpha1p	0.010
SMA2	Sma2p	0.010
GUP2	Gup2p	0.010	Yeast
DAD4	Dad4p	0.010
YPL038W-A	hypothetical protein	0.010
DTR1	Dtr1p	0.010
MDM32	Mdm32p	0.010
YFR018C	hypothetical protein	0.010
CTF13	Ctf13p	0.010
YDL186W	hypothetical protein	0.010
NKP2	Nkp2p	0.010
TIP1	Tip1p	0.010
RDN25-1	RDN25-1	0.010
YOR378W	hypothetical protein	0.010
FET4	Fet4p	0.010
BSD2	Bsd2p	0.010
APT2	Apt2p	0.010
SLO1	Slo1p	0.010
YHL012W	hypothetical protein	0.010
YBL039W-B	hypothetical protein	0.010
YGR117C	hypothetical protein	0.010
ALG2	Alg2p	0.010
YFR057W	hypothetical protein	0.010
PCM1	Pcm1p	0.010
NCE103	Nce103p	0.010
AAD4	Aad4p	0.010
YKL018C-A	hypothetical protein	0.010
PHM6	Phm6p	0.010
CAM1	Cam1p	0.010
HO	Hop	0.010
PRM3	Prm3p	0.010
YPL014W	hypothetical protein	0.010
VEL1	Vel1p	0.010
NRT1	Nrt1p	0.010
MNS1	Mns1p	0.010
YNL260C	hypothetical protein	0.010
YOR020W-A	hypothetical protein	0.010
STT4	Stt4p	0.010