Saccharomyces cerevisiae

375 genes annotated in yeast

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negative regulation of macromolecule metabolic process

GO:0010605

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

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