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Saccharomyces cerevisiae

30 genes annotated in yeast

mapk cascade

An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.

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In addition to gene-name show these genes:

Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mapk cascade"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mapk cascade" (in gray)

Name	Description	Probability	Func Analog Organism
PBS2	Pbs2p	0.999
NBP2	Nbp2p	0.993
SSK2	Ssk2p	0.983
SLT2	Slt2p	0.982	Yeast
BCK1	Bck1p	0.979
STE7	Ste7p	0.947
CLA4	Cla4p	0.890	Human Yeast Worm
KSS1	Kss1p	0.826
STE20	Ste20p	0.822
MSG5	Msg5p	0.810
SSK1	Ssk1p	0.774
SNT1	Snt1p	0.674
SHO1	Sho1p	0.595
STE11	Ste11p	0.589
ZDS1	Zds1p	0.565
FUS3	Fus3p	0.540
BCK2	Bck2p	0.511
RLM1	Rlm1p	0.499	Human Mouse
KDX1	Kdx1p	0.448	Yeast
SSK22	Ssk22p	0.442
HOG1	Hog1p	0.418
STE5	Ste5p	0.405
SOK1	Sok1p	0.387
CPR1	Cpr1p	0.286
HOS4	Hos4p	0.271
PIL1	Pil1p	0.236
BMH1	Bmh1p	0.213	Fly
VPS64	Vps64p	0.197
RGD1	Rgd1p	0.178
PPH21	Pph21p	0.169
SIF2	Sif2p	0.138
VMA13	Vma13p	0.116
TED1	Ted1p	0.111
CRZ1	Crz1p	0.110
CAK1	Cak1p	0.101
UFO1	Ufo1p	0.099
GAL7	Gal7p	0.094
KOG1	Kog1p	0.093
TAT1	Tat1p	0.091
AHP1	Ahp1p	0.088
ALD6	Ald6p	0.088
YTA6	Yta6p	0.081
STE4	Ste4p	0.078
EBS1	Ebs1p	0.076
SSN8	Ssn8p	0.076
CRG1	Crg1p	0.074
MRM1	Mrm1p	0.073
PCI8	Pci8p	0.073
ARF2	Arf2p	0.073
LHS1	Lhs1p	0.072
BOI2	Boi2p	0.067	Yeast
CDC34	Cdc34p	0.065
KIC1	Kic1p	0.065
PAM1	Pam1p	0.065
HST1	Hst1p	0.064
PTP2	Ptp2p	0.064
YHB1	Yhb1p	0.063
HSP60	Hsp60p	0.062
YPL088W	hypothetical protein	0.059
IRA1	Ira1p	0.059
ESF1	Esf1p	0.053
HKR1	Hkr1p	0.052
YPL150W	hypothetical protein	0.052
CDC24	Cdc24p	0.052
MNN2	Mnn2p	0.050
TRX2	Trx2p	0.048
NAB6	Nab6p	0.048
VPS5	Vps5p	0.048
SMP1	Smp1p	0.047	Human Mouse
CDC37	Cdc37p	0.047
HOR7	Hor7p	0.046
PPH3	Pph3p	0.045
RHO1	Rho1p	0.045
FAB1	Fab1p	0.045
ALO1	Alo1p	0.044
HSM3	Hsm3p	0.043
TEC1	Tec1p	0.043
RAS2	Ras2p	0.041	Human Rat Fly
YJR084W	hypothetical protein	0.040
FUS2	Fus2p	0.040
HOS2	Hos2p	0.040
OYE2	Oye2p	0.040
MDS3	Mds3p	0.039
TPS1	Tps1p	0.039
NRP1	Nrp1p	0.039
PTC1	Ptc1p	0.039
ASK10	Ask10p	0.038
SET1	Set1p	0.037
KEL3	Kel3p	0.036
BCY1	Bcy1p	0.036
AKL1	Akl1p	0.036
NUP157	Nup157p	0.035
GPX2	Gpx2p	0.034
OPY2	Opy2p	0.034
SMY2	Smy2p	0.034
DBF2	Dbf2p	0.034
YJL193W	hypothetical protein	0.033
PUS9	Pus9p	0.031
SKO1	Sko1p	0.031
MOB2	Mob2p	0.030
THP3	Thp3p	0.030
RHO4	Rho4p	0.030
BNI1	Bni1p	0.029
EHT1	Eht1p	0.029
SSL2	Ssl2p	0.029
DBP3	Dbp3p	0.028
MYO5	Myo5p	0.028
IKI1	Iki1p	0.028
SGD1	Sgd1p	0.027
PCL9	Pcl9p	0.027
DCN1	Dcn1p	0.027
EMW1	Emw1p	0.027
ZDS2	Zds2p	0.025
STE2	Ste2p	0.025
PTP3	Ptp3p	0.025
STE18	Ste18p	0.025
HYR1	Hyr1p	0.025
YCP4	Ycp4p	0.025
YPK3	Ypk3p	0.025
AIM9	Aim9p	0.025
CAP1	Cap1p	0.024
RRD1	Rrd1p	0.024
SET3	Set3p	0.024
CAM1	Cam1p	0.024
YGR205W	hypothetical protein	0.024
TFA2	Tfa2p	0.023
SKG6	Skg6p	0.023
ASH1	Ash1p	0.023
RMT2	Rmt2p	0.023
MNL1	Mnl1p	0.023
YOR342C	hypothetical protein	0.022
HRT3	Hrt3p	0.022
TIP41	Tip41p	0.022
CRP1	Crp1p	0.022
FAR1	Far1p	0.022
YFR016C	hypothetical protein	0.022
CTF13	Ctf13p	0.022
PTC2	Ptc2p	0.022
YJR141W	hypothetical protein	0.022
YJL213W	hypothetical protein	0.021
TRS65	Trs65p	0.021
GYL1	Gyl1p	0.021
LAT1	Lat1p	0.021
MKK2	Mkk2p	0.020	Human Yeast Mouse Rat Worm Fly
RRI2	Rri2p	0.020
PRS2	Prs2p	0.020
TCO89	Tco89p	0.020
SHP1	Shp1p	0.020
MSB2	Msb2p	0.019
RPO31	Rpo31p	0.019
ARP10	Arp10p	0.019
PPQ1	Ppq1p	0.019
GLG2	Glg2p	0.019
YBL029W	hypothetical protein	0.018
ELP4	Elp4p	0.018
DIG1	Dig1p	0.018
VPS75	Vps75p	0.018
SRD1	Srd1p	0.018
PTC3	Ptc3p	0.018
URA3	Ura3p	0.018
ARE2	Are2p	0.018
SKI3	Ski3p	0.018
ATG14	Atg14p	0.018
CDC55	Cdc55p	0.018
YNL134C	hypothetical protein	0.017
BOI1	Boi1p	0.017	Yeast
HBT1	Hbt1p	0.017
RTT10	Rtt10p	0.017	Yeast
YLR162W	hypothetical protein	0.017
YEL1	Yel1p	0.017
YDR132C	hypothetical protein	0.017
CNS1	Cns1p	0.017
DAS2	Das2p	0.017
YLR225C	hypothetical protein	0.016
EFM1	Efm1p	0.016
PDI1	Pdi1p	0.016
YIL151C	hypothetical protein	0.016
CPR2	Cpr2p	0.016
YLR264C-A	hypothetical protein	0.016
ROM2	Rom2p	0.016
EAF3	Eaf3p	0.016
YOR111W	hypothetical protein	0.016
OSH3	Osh3p	0.016
JEM1	Jem1p	0.016
LEU2	Leu2p	0.015
ATG21	Atg21p	0.015
CCT2	Cct2p	0.015
YPD1	Ypd1p	0.015
YOL038C-A	hypothetical protein	0.015
SKM1	Skm1p	0.015	Human Yeast Worm
CUP1-1	Cup1-1p	0.015
VPS38	Vps38p	0.015
BIT2	Bit2p	0.014
SRP54	Srp54p	0.014
EDC1	Edc1p	0.014
VPS55	Vps55p	0.014
STB5	Stb5p	0.014
YDR348C	hypothetical protein	0.014
DAS1	Das1p	0.014
CNE1	Cne1p	0.014
SLA2	Sla2p	0.014
UBP1	Ubp1p	0.014
YNR014W	hypothetical protein	0.014
DIA2	Dia2p	0.014
AQY2	Aqy2p	0.013
ARO10	Aro10p	0.013
SCS2	Scs2p	0.013
RFU1	Rfu1p	0.013
YIR035C	hypothetical protein	0.013
UTR4	Utr4p	0.013
SML1	Sml1p	0.013
BUD9	Bud9p	0.013
YAR068W	hypothetical protein	0.013
RPN14	Rpn14p	0.013
YIR014W	hypothetical protein	0.013
ITT1	Itt1p	0.013
YKR017C	hypothetical protein	0.013
DBP8	Dbp8p	0.013
YLL053C	hypothetical protein	0.013
ABD1	Abd1p	0.013
LCB4	Lcb4p	0.013
MSL5	Msl5p	0.013
REE1	Ree1p	0.013
CHA1	Cha1p	0.012
PTR2	Ptr2p	0.012
SIS2	Sis2p	0.012
YCL021W-A	hypothetical protein	0.012
MAK10	Mak10p	0.012
CTI6	Cti6p	0.012
HPF1	Hpf1p	0.012
MSN4	Msn4p	0.012
ALG13	Alg13p	0.012
YLR132C	hypothetical protein	0.012
DUG1	Dug1p	0.012
TYE7	Tye7p	0.012
SRX1	Srx1p	0.012
YBR013C	hypothetical protein	0.012
MER1	Mer1p	0.012
SIL1	Sil1p	0.012
SRO77	Sro77p	0.012
STE12	Ste12p	0.011
TMA108	Tma108p	0.011
PIN4	Pin4p	0.011
ECM31	Ecm31p	0.011
GPH1	Gph1p	0.011
SUT1	Sut1p	0.011
NSE4	Nse4p	0.011
KNH1	Knh1p	0.011
STT4	Stt4p	0.011
AIM43	Aim43p	0.011
NNF2	Nnf2p	0.011
CSI1	Csi1p	0.011
HPT1	Hpt1p	0.011
YJL107C	hypothetical protein	0.011
YPR157W	hypothetical protein	0.011
TOR1	Tor1p	0.011
SNF4	Snf4p	0.011
CDS1	Cds1p	0.011
PIB2	Pib2p	0.011
DUR1,2	Dur1,2p	0.011
MKK1	Mkk1p	0.011	Human Yeast Mouse Rat Fly
GIC1	Gic1p	0.011
PRM5	Prm5p	0.011
MCH5	Mch5p	0.010
YLR042C	hypothetical protein	0.010
KAP123	Kap123p	0.010
SPL2	Spl2p	0.010
TAL1	Tal1p	0.010
CPD1	Cpd1p	0.010
TPO3	Tpo3p	0.010
AAD6	Aad6p	0.010
SWT21	Swt21p	0.010
YCR102C	hypothetical protein	0.010
CAD1	Cad1p	0.010
RPH1	Rph1p	0.010
ADY2	Ady2p	0.010
BOP2	Bop2p	0.010
CWP1	Cwp1p	0.010