IMP

Process View

Saccharomyces cerevisiae

37 genes annotated in yeast

negative regulation of protein modification process

Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein modification process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of protein modification process" (in gray)

Name	Description	Probability	Func Analog Organism
PSR2	Psr2p	0.222	Mouse
BOI1	Boi1p	0.166	Yeast
SIC1	Sic1p	0.152
CKB1	Ckb1p	0.140
PIL1	Pil1p	0.108
SHO1	Sho1p	0.077
SSA3	Ssa3p	0.068	Human
ROM2	Rom2p	0.066
CAK1	Cak1p	0.056
PBS2	Pbs2p	0.056
MYO5	Myo5p	0.051
RSC6	Rsc6p	0.049
STI1	Sti1p	0.048
SLX8	Slx8p	0.048
INP53	Inp53p	0.047
SSE1	Sse1p	0.046	Rat
BRX1	Brx1p	0.043
SIS1	Sis1p	0.042
DPB2	Dpb2p	0.041
URN1	Urn1p	0.041
ERB1	Erb1p	0.040
YDJ1	Ydj1p	0.039
PPH21	Pph21p	0.039
SSA2	Ssa2p	0.039	Human
MLP2	Mlp2p	0.038
CKA1	Cka1p	0.037	Fly
SSA4	Ssa4p	0.035	Human
AHA1	Aha1p	0.034
BMH1	Bmh1p	0.034
CDH1	Cdh1p	0.033
LSP1	Lsp1p	0.033
CAM1	Cam1p	0.033
MKS1	Mks1p	0.032
SOG2	Sog2p	0.032
KIN3	Kin3p	0.031
BCK1	Bck1p	0.031
HKR1	Hkr1p	0.031
PKH1	Pkh1p	0.030	Human
HSP78	Hsp78p	0.030
YHB1	Yhb1p	0.029
TOM1	Tom1p	0.029
TAF11	Taf11p	0.029
KIC1	Kic1p	0.028
PTC2	Ptc2p	0.028
RIF1	Rif1p	0.028
PDR1	Pdr1p	0.028
MKK1	Mkk1p	0.028
BST1	Bst1p	0.028
HOT1	Hot1p	0.027
NOP2	Nop2p	0.027
ESF1	Esf1p	0.027
CDC6	Cdc6p	0.026
PSR1	Psr1p	0.026	Mouse
MDH1	Mdh1p	0.026
SPT16	Spt16p	0.026
SPT6	Spt6p	0.025
REG1	Reg1p	0.025
ADR1	Adr1p	0.025
YGR126W	hypothetical protein	0.024
CDC28	Cdc28p	0.024
CSE4	Cse4p	0.024
SAC7	Sac7p	0.024
NPL3	Npl3p	0.023
BMH2	Bmh2p	0.023
UBC4	Ubc4p	0.023
CAB3	Cab3p	0.023
PDS1	Pds1p	0.022
CLB3	Clb3p	0.022	Yeast Rat
CPR6	Cpr6p	0.022
FAB1	Fab1p	0.022
YTA6	Yta6p	0.022
NUP157	Nup157p	0.021
BCK2	Bck2p	0.021
SOK1	Sok1p	0.021
VPS5	Vps5p	0.021
SAT4	Sat4p	0.020
GSC2	Gsc2p	0.020
WWM1	Wwm1p	0.020
RPI1	Rpi1p	0.020
MOT1	Mot1p	0.019
KAR2	Kar2p	0.019
RDH54	Rdh54p	0.019
SSA1	Ssa1p	0.019	Human
YCR051W	hypothetical protein	0.019
FES1	Fes1p	0.019
BRO1	Bro1p	0.019
YMR086W	hypothetical protein	0.018
NBP2	Nbp2p	0.018
MMS21	Mms21p	0.018
RGC1	Rgc1p	0.018
NET1	Net1p	0.018
DOT6	Dot6p	0.018
PAN1	Pan1p	0.018
VPS75	Vps75p	0.018
PKH3	Pkh3p	0.018	Human
CDC37	Cdc37p	0.018
SKG6	Skg6p	0.018
MOB2	Mob2p	0.017
SGT2	Sgt2p	0.017
IMP2'	Imp2'p	0.017
FKH1	Fkh1p	0.017
YGP1	Ygp1p	0.017
CSF1	Csf1p	0.017
TAF8	Taf8p	0.017
CDC55	Cdc55p	0.017
YJL160C	hypothetical protein	0.017
SET1	Set1p	0.017
RFC1	Rfc1p	0.017
GEA2	Gea2p	0.017
YGL010W	hypothetical protein	0.017
AEP3	Aep3p	0.017
KEL3	Kel3p	0.017
SRO77	Sro77p	0.016
SKP1	Skp1p	0.016
NOP10	Nop10p	0.016
STE20	Ste20p	0.016
OCH1	Och1p	0.016
CLB6	Clb6p	0.016	Yeast Rat
TMN3	Tmn3p	0.016
MSG5	Msg5p	0.016
SWE1	Swe1p	0.016
LOC1	Loc1p	0.016
WSC4	Wsc4p	0.016
MNN2	Mnn2p	0.016
SAS3	Sas3p	0.016
SLG1	Slg1p	0.016
CLU1	Clu1p	0.016
MIG1	Mig1p	0.016
RRP5	Rrp5p	0.016
RRS1	Rrs1p	0.016
AZF1	Azf1p	0.016
CCR4	Ccr4p	0.016
YDR034W-B	hypothetical protein	0.016
YGR205W	hypothetical protein	0.016
SHP1	Shp1p	0.016
STE24	Ste24p	0.016
SKM1	Skm1p	0.016
PPQ1	Ppq1p	0.015
CDC20	Cdc20p	0.015
BUD7	Bud7p	0.015
SSP120	Ssp120p	0.015
TRS65	Trs65p	0.015
RTS1	Rts1p	0.015
ARE2	Are2p	0.015
SPO16	Spo16p	0.015
YLR264C-A	hypothetical protein	0.015
CNB1	Cnb1p	0.015
GCN20	Gcn20p	0.015
DOP1	Dop1p	0.015
HAS1	Has1p	0.015
NOP7	Nop7p	0.015
MAD3	Mad3p	0.015
SNG1	Sng1p	0.015
OYE2	Oye2p	0.015
YOR111W	hypothetical protein	0.015
CRP1	Crp1p	0.015
RNR4	Rnr4p	0.015
TAO3	Tao3p	0.015
EIS1	Eis1p	0.015
YME1	Yme1p	0.015
VHS2	Vhs2p	0.014
GIP2	Gip2p	0.014
PPH22	Pph22p	0.014
YPL014W	hypothetical protein	0.014
STE7	Ste7p	0.014
YPL199C	hypothetical protein	0.014
RPN2	Rpn2p	0.014
SUR1	Sur1p	0.014
SPR6	Spr6p	0.014
NVJ1	Nvj1p	0.014
HTA1	Hta1p	0.014
SPC110	Spc110p	0.014
NHX1	Nhx1p	0.014
YBR296C-A	hypothetical protein	0.014
GLG2	Glg2p	0.014
APJ1	Apj1p	0.014
ARR2	Arr2p	0.014
PCL9	Pcl9p	0.014
ERP5	Erp5p	0.014
SRD1	Srd1p	0.014
YLR132C	hypothetical protein	0.014
MTW1	Mtw1p	0.014
GEA1	Gea1p	0.014
CLN1	Cln1p	0.014
FAA4	Faa4p	0.014
TIP1	Tip1p	0.014
ICS2	Ics2p	0.014
SLX5	Slx5p	0.014
MKK2	Mkk2p	0.014
UGO1	Ugo1p	0.014
YCF1	Ycf1p	0.014
YOL038C-A	hypothetical protein	0.014
CLB5	Clb5p	0.014	Yeast Rat
NUD1	Nud1p	0.014
SNF1	Snf1p	0.014
ACC1	Acc1p	0.014
HOG1	Hog1p	0.013	Fly
PTP3	Ptp3p	0.013
BRE5	Bre5p	0.013
VPS21	Vps21p	0.013
KIN2	Kin2p	0.013
REV1	Rev1p	0.013
DPH5	Dph5p	0.013
MPT5	Mpt5p	0.013
RLM1	Rlm1p	0.013
VMA13	Vma13p	0.013
CYC7	Cyc7p	0.013
YOL036W	hypothetical protein	0.013
FIR1	Fir1p	0.013
AVL9	Avl9p	0.013
YIL151C	hypothetical protein	0.013
ADH2	Adh2p	0.013
NNF2	Nnf2p	0.013
VPS8	Vps8p	0.013
HXT3	Hxt3p	0.013
URA6	Ura6p	0.013
SCH9	Sch9p	0.013
UBP5	Ubp5p	0.013
POL2	Pol2p	0.013
ECM27	Ecm27p	0.013
YLR278C	hypothetical protein	0.013
LDB7	Ldb7p	0.013
MOB1	Mob1p	0.013
PNS1	Pns1p	0.013
CUP1-1	Cup1-1p	0.013
SIT4	Sit4p	0.013
SLA2	Sla2p	0.013
CCT2	Cct2p	0.013
SFB3	Sfb3p	0.013
CHA1	Cha1p	0.013
PAM1	Pam1p	0.013
HEM14	Hem14p	0.013
LSB5	Lsb5p	0.013
VAC17	Vac17p	0.013
MSI1	Msi1p	0.013
LEU2	Leu2p	0.013
KAP104	Kap104p	0.013
HO	Hop	0.013
ARP10	Arp10p	0.013
KIN4	Kin4p	0.013
YLR162W	hypothetical protein	0.013
MVB12	Mvb12p	0.013
AAP1	Aap1p	0.013
CKS1	Cks1p	0.012
SGO1	Sgo1p	0.012
OPT2	Opt2p	0.012
SMC2	Smc2p	0.012
TAF3	Taf3p	0.012
KGD1	Kgd1p	0.012
PER1	Per1p	0.012
NDD1	Ndd1p	0.012
EBS1	Ebs1p	0.012
ALD6	Ald6p	0.012
CHC1	Chc1p	0.012
SSK22	Ssk22p	0.012
MCM10	Mcm10p	0.012
VCX1	Vcx1p	0.012
FIN1	Fin1p	0.012
VMA7	Vma7p	0.012
HCR1	Hcr1p	0.012
VIK1	Vik1p	0.012
ARC18	Arc18p	0.012
YPD1	Ypd1p	0.012
SAS10	Sas10p	0.012
SPE3	Spe3p	0.012
BTN2	Btn2p	0.012
GIS3	Gis3p	0.012
YLR419W	hypothetical protein	0.012
SCP1	Scp1p	0.012
YML096W	hypothetical protein	0.012
TMA22	Tma22p	0.012
EFM1	Efm1p	0.012
SAK1	Sak1p	0.012
SPS4	Sps4p	0.012
YAR068W	hypothetical protein	0.012
YGL082W	hypothetical protein	0.012
MER1	Mer1p	0.012
WHI2	Whi2p	0.012
RAX2	Rax2p	0.012
VHS3	Vhs3p	0.012
UPS3	Ups3p	0.012
YPT11	Ypt11p	0.012
MDM32	Mdm32p	0.012
KIP2	Kip2p	0.012
SFA1	Sfa1p	0.012
ATP6	Atp6p	0.012
MEC1	Mec1p	0.012
NOP4	Nop4p	0.012
CWP1	Cwp1p	0.012
SLT2	Slt2p	0.012
YNR014W	hypothetical protein	0.012
HIF1	Hif1p	0.012
FCY21	Fcy21p	0.012
SPC29	Spc29p	0.012
CDC14	Cdc14p	0.012
OTU2	Otu2p	0.012
TRK1	Trk1p	0.012
CPD1	Cpd1p	0.012
CNE1	Cne1p	0.012
RSR1	Rsr1p	0.012
MAK5	Mak5p	0.012
YIR035C	hypothetical protein	0.012
SYN8	Syn8p	0.012
SPC98	Spc98p	0.012
YIL152W	hypothetical protein	0.012
KRE5	Kre5p	0.012
YBR013C	hypothetical protein	0.012
SOL2	Sol2p	0.012
ARG8	Arg8p	0.012
YBR184W	hypothetical protein	0.012
SPL2	Spl2p	0.011
SRO7	Sro7p	0.011
YDL057W	hypothetical protein	0.011
SSK1	Ssk1p	0.011
EXO84	Exo84p	0.011
AAD6	Aad6p	0.011
MOT3	Mot3p	0.011
YJR012C	hypothetical protein	0.011
YGR017W	hypothetical protein	0.011
SKG3	Skg3p	0.011
YMR295C	hypothetical protein	0.011
DUR1,2	Dur1,2p	0.011
UTP22	Utp22p	0.011
GYL1	Gyl1p	0.011
ART5	Art5p	0.011
BIK1	Bik1p	0.011
FET4	Fet4p	0.011
YBR016W	hypothetical protein	0.011
OXA1	Oxa1p	0.011
YLR346C	hypothetical protein	0.011
GIP3	Gip3p	0.011
RRD1	Rrd1p	0.011
RPA190	Rpa190p	0.011
YER140W	hypothetical protein	0.011
CCH1	Cch1p	0.011
YIR042C	hypothetical protein	0.011
ASG1	Asg1p	0.011
SPA2	Spa2p	0.011
HOR7	Hor7p	0.011
UGP1	Ugp1p	0.011
MSS4	Mss4p	0.011
REE1	Ree1p	0.011
TCB2	Tcb2p	0.011
SRT1	Srt1p	0.011
SPC42	Spc42p	0.011
AUA1	Aua1p	0.011
SCC4	Scc4p	0.011
TSC3	Tsc3p	0.011
RRP15	Rrp15p	0.011
ULP2	Ulp2p	0.011
PHM6	Phm6p	0.011
YHL008C	hypothetical protein	0.011
RAS2	Ras2p	0.011
YCH1	Ych1p	0.011
LCB4	Lcb4p	0.011
DAL7	Dal7p	0.011
YEH2	Yeh2p	0.011
YGR169C-A	hypothetical protein	0.011
YRO2	Yro2p	0.011
HPF1	Hpf1p	0.011
YSC83	Ysc83p	0.011
FSF1	Fsf1p	0.011
SEN1	Sen1p	0.011
GAL83	Gal83p	0.011
YER152C	hypothetical protein	0.011
YLL007C	hypothetical protein	0.011
PDA1	Pda1p	0.011
HXT4	Hxt4p	0.011
CCP1	Ccp1p	0.011
ZPS1	Zps1p	0.011
DIC1	Dic1p	0.011
YMR259C	hypothetical protein	0.011
BCH2	Bch2p	0.011
TIM44	Tim44p	0.011
BRN1	Brn1p	0.011
ASN2	Asn2p	0.011
PEX22	Pex22p	0.011
BET4	Bet4p	0.011
FPR4	Fpr4p	0.011
RAD16	Rad16p	0.011
HBT1	Hbt1p	0.011
KIN1	Kin1p	0.011
YKR045C	hypothetical protein	0.011
SCT1	Sct1p	0.011
YPR157W	hypothetical protein	0.011
NSA1	Nsa1p	0.011
NPP1	Npp1p	0.011	Human
BLM10	Blm10p	0.011
ASK10	Ask10p	0.011
HOS4	Hos4p	0.011	Yeast
YOL013W-A	hypothetical protein	0.011
SMC6	Smc6p	0.011
COX1	Cox1p	0.011
YMR124W	hypothetical protein	0.011
CPR8	Cpr8p	0.011
SEC17	Sec17p	0.011
YMR144W	hypothetical protein	0.011
ESS1	Ess1p	0.011
NOG1	Nog1p	0.011	Human
ZRT2	Zrt2p	0.011
YDR348C	hypothetical protein	0.011
FMT1	Fmt1p	0.011
PHM8	Phm8p	0.011
MF(ALPHA)2	Mf(alpha)2p	0.010
TOF1	Tof1p	0.010
STB1	Stb1p	0.010
LIN1	Lin1p	0.010
URA3	Ura3p	0.010
SGV1	Sgv1p	0.010
MTM1	Mtm1p	0.010
INP52	Inp52p	0.010
AQR1	Aqr1p	0.010
CAR2	Car2p	0.010
ESC8	Esc8p	0.010
DAS2	Das2p	0.010
COX4	Cox4p	0.010
BAT2	Bat2p	0.010
DYN3	Dyn3p	0.010
PER33	Per33p	0.010
VPS3	Vps3p	0.010
HLR1	Hlr1p	0.010
YBR138C	hypothetical protein	0.010
BUD23	Bud23p	0.010
YDR186C	hypothetical protein	0.010
CDC4	Cdc4p	0.010
PXA1	Pxa1p	0.010
SCY1	Scy1p	0.010
GIP4	Gip4p	0.010
YPR096C	hypothetical protein	0.010
YIR014W	hypothetical protein	0.010
YER039C-A	hypothetical protein	0.010
MTC5	Mtc5p	0.010
YJL185C	hypothetical protein	0.010
UTP20	Utp20p	0.010
MRM1	Mrm1p	0.010
CRR1	Crr1p	0.010
SET2	Set2p	0.010
APE3	Ape3p	0.010
SHY1	Shy1p	0.010
HHO1	Hho1p	0.010
YJR120W	hypothetical protein	0.010
YNL058C	hypothetical protein	0.010
MAP2	Map2p	0.010
SPB4	Spb4p	0.010
MYO4	Myo4p	0.010
RHO1	Rho1p	0.010
CIN1	Cin1p	0.010
TKL2	Tkl2p	0.010
YDL233W	hypothetical protein	0.010
VTC2	Vtc2p	0.010
BNA4	Bna4p	0.010
CRS5	Crs5p	0.010
SCM4	Scm4p	0.010
YOL014W	hypothetical protein	0.010
AAD15	Aad15p	0.010
INP1	Inp1p	0.010
YJR098C	hypothetical protein	0.010
CDC25	Cdc25p	0.010