IMP

Process View

Saccharomyces cerevisiae

35 genes annotated in yeast

anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CDC27	Cdc27p	0.999
CDC23	Cdc23p	0.999
CDC16	Cdc16p	0.999
DOC1	Doc1p	0.998
APC2	Apc2p	0.993
PPH22	Pph22p	0.968
PPH21	Pph21p	0.957
APC4	Apc4p	0.954
MND2	Mnd2p	0.952
SWM1	Swm1p	0.950
APC1	Apc1p	0.949
CDC20	Cdc20p	0.929
APC5	Apc5p	0.917
CDC26	Cdc26p	0.888
GLC7	Glc7p	0.886
APC9	Apc9p	0.856
MAD2	Mad2p	0.845
CDC55	Cdc55p	0.798	Fly
YPI1	Ypi1p	0.665
RTS1	Rts1p	0.508
PIG2	Pig2p	0.498	Yeast
SLK19	Slk19p	0.445
CDH1	Cdh1p	0.395
CHL4	Chl4p	0.339
GIP2	Gip2p	0.329	Yeast
RPT4	Rpt4p	0.299
PPZ1	Ppz1p	0.284
RPT1	Rpt1p	0.274
KIP1	Kip1p	0.231
TIP41	Tip41p	0.228
PSH1	Psh1p	0.223
MAD1	Mad1p	0.219
CTF3	Ctf3p	0.208
HTA1	Hta1p	0.197
KIC1	Kic1p	0.187
HHF2	Hhf2p	0.180
FMP48	Fmp48p	0.172
PRE10	Pre10p	0.170
ECO1	Eco1p	0.166
APC11	Apc11p	0.159
RPN3	Rpn3p	0.150
NSL1	Nsl1p	0.142
SPC24	Spc24p	0.141
NBL1	Nbl1p	0.134
PDS1	Pds1p	0.133
PUP2	Pup2p	0.104
PRE2	Pre2p	0.100
MAD3	Mad3p	0.099
RPN6	Rpn6p	0.097
YKL075C	hypothetical protein	0.095
MMS21	Mms21p	0.093
SDS22	Sds22p	0.090
RPT3	Rpt3p	0.090
GSY1	Gsy1p	0.089
RPN9	Rpn9p	0.089
MCM21	Mcm21p	0.083
RPN7	Rpn7p	0.078
CSE4	Cse4p	0.077
PRE6	Pre6p	0.072
CDC28	Cdc28p	0.072
PUP1	Pup1p	0.069
RPN11	Rpn11p	0.068
PUP3	Pup3p	0.068
RPN2	Rpn2p	0.065
PRE1	Pre1p	0.065
IRC15	Irc15p	0.061
BUB1	Bub1p	0.058
STU1	Stu1p	0.056
HHT1	Hht1p	0.055	Yeast
ECM29	Ecm29p	0.053
YBP2	Ybp2p	0.052
IPL1	Ipl1p	0.052
SMC4	Smc4p	0.050
PRE7	Pre7p	0.049
NTO1	Nto1p	0.047
CDC37	Cdc37p	0.046
VIK1	Vik1p	0.045
PTI1	Pti1p	0.045
SPC25	Spc25p	0.044
BUB3	Bub3p	0.041	Worm Fly
SLI15	Sli15p	0.041
RPT2	Rpt2p	0.041
IML3	Iml3p	0.040
MEC1	Mec1p	0.040
GAC1	Gac1p	0.039
ZDS1	Zds1p	0.036
HYM1	Hym1p	0.035
MTW1	Mtw1p	0.034
SPC110	Spc110p	0.033
SRD1	Srd1p	0.033
TID3	Tid3p	0.032
SPC105	Spc105p	0.032
PCL10	Pcl10p	0.031
BFA1	Bfa1p	0.031
ASE1	Ase1p	0.031
CTF13	Ctf13p	0.029
POP6	Pop6p	0.029
MEI5	Mei5p	0.029
HST3	Hst3p	0.029
YOL038C-A	hypothetical protein	0.028
CIN1	Cin1p	0.028
RAD30	Rad30p	0.028
PRE4	Pre4p	0.028
RPN12	Rpn12p	0.027
RPN14	Rpn14p	0.027
SOG2	Sog2p	0.027
YLR264C-A	hypothetical protein	0.027
CTF19	Ctf19p	0.027
IKI1	Iki1p	0.027
YNL155W	hypothetical protein	0.026
MER1	Mer1p	0.026
ARG8	Arg8p	0.026
AME1	Ame1p	0.026
LEU2	Leu2p	0.026
MRK1	Mrk1p	0.026
CRP1	Crp1p	0.026
YNL144C	hypothetical protein	0.025
MND1	Mnd1p	0.025
YLR162W	hypothetical protein	0.025
YAR068W	hypothetical protein	0.025
PRP28	Prp28p	0.025
SKM1	Skm1p	0.025
SMC6	Smc6p	0.025
VHS2	Vhs2p	0.024
CFD1	Cfd1p	0.024
NSE4	Nse4p	0.023
MPH1	Mph1p	0.023
YNR062C	hypothetical protein	0.023
PKC1	Pkc1p	0.023
ZPS1	Zps1p	0.023
CBF1	Cbf1p	0.022
IME4	Ime4p	0.022
RTS2	Rts2p	0.022
CUP1-1	Cup1-1p	0.022
SUR1	Sur1p	0.022
RAD61	Rad61p	0.021
GLG1	Glg1p	0.021
PRS2	Prs2p	0.021
YLR407W	hypothetical protein	0.021
RMD5	Rmd5p	0.021
THP3	Thp3p	0.021
CDC7	Cdc7p	0.021
HHO1	Hho1p	0.020
YBR013C	hypothetical protein	0.020
KRE29	Kre29p	0.020
SAP4	Sap4p	0.020
ADH2	Adh2p	0.020
SPL2	Spl2p	0.020
CLB1	Clb1p	0.020
AGE1	Age1p	0.020
ZIP1	Zip1p	0.020
ARP10	Arp10p	0.020
YNR014W	hypothetical protein	0.020
CPD1	Cpd1p	0.020
YLR042C	hypothetical protein	0.020
YKR075C	hypothetical protein	0.020
YML053C	hypothetical protein	0.019
MET12	Met12p	0.019
HPF1	Hpf1p	0.019
YAR066W	hypothetical protein	0.019
NUF2	Nuf2p	0.019
YGK3	Ygk3p	0.019
URA3	Ura3p	0.019
EAF1	Eaf1p	0.019
ATP6	Atp6p	0.018
OKP1	Okp1p	0.018
SWC7	Swc7p	0.018
UBR1	Ubr1p	0.018
AAD6	Aad6p	0.018
YBR296C-A	hypothetical protein	0.018
AQR1	Aqr1p	0.018
YPR157W	hypothetical protein	0.018
SPO12	Spo12p	0.018
YOL013W-A	hypothetical protein	0.018
UPS3	Ups3p	0.018
SCM3	Scm3p	0.018
AUA1	Aua1p	0.017
FMT1	Fmt1p	0.017
MCM22	Mcm22p	0.017
BRN1	Brn1p	0.017
SPS4	Sps4p	0.017
YGR035C	hypothetical protein	0.017
BIT61	Bit61p	0.017
PUF2	Puf2p	0.017
RPN1	Rpn1p	0.017
SCC2	Scc2p	0.017
CDC4	Cdc4p	0.017
VBA5	Vba5p	0.017
ESP1	Esp1p	0.017
OPT2	Opt2p	0.016
HXT3	Hxt3p	0.016
YIL151C	hypothetical protein	0.016
ICS2	Ics2p	0.016
SGE1	Sge1p	0.016
MF(ALPHA)2	Mf(alpha)2p	0.016
YML003W	hypothetical protein	0.016
YIR035C	hypothetical protein	0.016
ARE2	Are2p	0.016
YHR033W	hypothetical protein	0.016
MPS1	Mps1p	0.016
YHR131C	hypothetical protein	0.016
PDR15	Pdr15p	0.016
TOD6	Tod6p	0.016
NDD1	Ndd1p	0.015
BDF2	Bdf2p	0.015
UFD1	Ufd1p	0.015
IML1	Iml1p	0.015
PCT1	Pct1p	0.015
HHT2	Hht2p	0.015
MIF2	Mif2p	0.015
MSS4	Mss4p	0.015
SSP1	Ssp1p	0.015
KAR3	Kar3p	0.015
CAR1	Car1p	0.015
CDC15	Cdc15p	0.015
RRT5	Rrt5p	0.015
DAM1	Dam1p	0.014
YDL206W	hypothetical protein	0.014
LIF1	Lif1p	0.014
INO80	Ino80p	0.014
TPI1	Tpi1p	0.014
YAL037C-A	hypothetical protein	0.014
ALT2	Alt2p	0.014
HOR2	Hor2p	0.014
YNL234W	hypothetical protein	0.014
BSC1	Bsc1p	0.014
CHA1	Cha1p	0.014
GIP3	Gip3p	0.014
CEF1	Cef1p	0.014
BOI1	Boi1p	0.014
BNA4	Bna4p	0.014
RPN8	Rpn8p	0.014
OAF1	Oaf1p	0.014
AAD15	Aad15p	0.014
YLR281C	hypothetical protein	0.014
YGL006W-A	hypothetical protein	0.014
ART10	Art10p	0.014
TAF7	Taf7p	0.014
SET4	Set4p	0.014
YJL147C	hypothetical protein	0.013
SCL1	Scl1p	0.013
ARR2	Arr2p	0.013
YLR040C	hypothetical protein	0.013
IZH4	Izh4p	0.013
SWC4	Swc4p	0.013
OSH3	Osh3p	0.013
FYV10	Fyv10p	0.013
YPL068C	hypothetical protein	0.013
FPK1	Fpk1p	0.013
PSK1	Psk1p	0.013
PTR2	Ptr2p	0.013
ATG20	Atg20p	0.013
YBL029W	hypothetical protein	0.013
RNP1	Rnp1p	0.013
PPR1	Ppr1p	0.013
JLP2	Jlp2p	0.013
YOR385W	hypothetical protein	0.013
MMP1	Mmp1p	0.013
YLR445W	hypothetical protein	0.013
DIC1	Dic1p	0.013
YJL160C	hypothetical protein	0.013
ERV2	Erv2p	0.013
MFA2	Mfa2p	0.013
NRG2	Nrg2p	0.013
YNL067W-B	hypothetical protein	0.013
YAL064W	hypothetical protein	0.013
YOR012W	hypothetical protein	0.013
TYE7	Tye7p	0.013
PMA2	Pma2p	0.013
SPO13	Spo13p	0.013
RRN5	Rrn5p	0.012
SPO19	Spo19p	0.012
RPN10	Rpn10p	0.012
YHR035W	hypothetical protein	0.012
RPI1	Rpi1p	0.012
RTT105	Rtt105p	0.012
YIL001W	hypothetical protein	0.012
SLD3	Sld3p	0.012
YDR186C	hypothetical protein	0.012
DUR1,2	Dur1,2p	0.012
CAB4	Cab4p	0.012
SRO77	Sro77p	0.012
PRE5	Pre5p	0.012
WSS1	Wss1p	0.012
YNL033W	hypothetical protein	0.012
YPR096C	hypothetical protein	0.012
YPL067C	hypothetical protein	0.012
YDR506C	hypothetical protein	0.012
SFT1	Sft1p	0.012
TRI1	Tri1p	0.012
DIF1	Dif1p	0.012
MF(ALPHA)1	Mf(alpha)1p	0.012
YDL186W	hypothetical protein	0.012
RFA1	Rfa1p	0.012
ENA5	Ena5p	0.012
LEU3	Leu3p	0.011
AMA1	Ama1p	0.011	Human Yeast
JHD2	Jhd2p	0.011
YCR050C	hypothetical protein	0.011
TFA1	Tfa1p	0.011
HIR1	Hir1p	0.011
YOR387C	hypothetical protein	0.011
YOR262W	hypothetical protein	0.011
YPR027C	hypothetical protein	0.011
HSM3	Hsm3p	0.011
EST2	Est2p	0.011
ARO10	Aro10p	0.011
YDR179W-A	hypothetical protein	0.011
YMR317W	hypothetical protein	0.011
PHM6	Phm6p	0.011
LCL1	Lcl1p	0.011
YCH1	Ych1p	0.011
TIR3	Tir3p	0.011
IME1	Ime1p	0.011
SCM4	Scm4p	0.011
YJR120W	hypothetical protein	0.011
VHS3	Vhs3p	0.011
ICS3	Ics3p	0.011
SMC5	Smc5p	0.011	Human
YJL218W	hypothetical protein	0.011
YAL018C	hypothetical protein	0.011
YML100W-A	hypothetical protein	0.011
SRX1	Srx1p	0.011
CTS1	Cts1p	0.011
YBR138C	hypothetical protein	0.011
RAD53	Rad53p	0.011
LUC7	Luc7p	0.011
YCR102C	hypothetical protein	0.011
YDL129W	hypothetical protein	0.011
YPR153W	hypothetical protein	0.011
YBL044W	hypothetical protein	0.011
YKR041W	hypothetical protein	0.011
YDR034C-A	hypothetical protein	0.011
DNA2	Dna2p	0.011
YNL018C	hypothetical protein	0.011
SPS22	Sps22p	0.011
YLR412C-A	hypothetical protein	0.011
YGL262W	hypothetical protein	0.010
CEP3	Cep3p	0.010
YKL070W	hypothetical protein	0.010
YFR057W	hypothetical protein	0.010
YIR042C	hypothetical protein	0.010
YHK8	Yhk8p	0.010
YPR159C-A	hypothetical protein	0.010
HMRA1	Hmra1p	0.010
PBP2	Pbp2p	0.010
RHO1	Rho1p	0.010
IOC4	Ioc4p	0.010
KNH1	Knh1p	0.010
MAM1	Mam1p	0.010
AIF1	Aif1p	0.010
IRC8	Irc8p	0.010
YCL001W-B	hypothetical protein	0.010
MIG2	Mig2p	0.010
KTR5	Ktr5p	0.010
DTR1	Dtr1p	0.010