IMP

Process View

Saccharomyces cerevisiae

27 genes annotated in yeast

negative regulation of gene silencing

Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.

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In addition to gene-name show these genes:

Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of gene silencing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of gene silencing" (in gray)

Name	Description	Probability	Func Analog Organism
CTI6	Cti6p	0.831
SIN3	Sin3p	0.735
PHO23	Pho23p	0.616
RXT2	Rxt2p	0.536
UME1	Ume1p	0.482
RPD3	Rpd3p	0.431
RNR2	Rnr2p	0.406
SAP30	Sap30p	0.318
SDS3	Sds3p	0.284
NTO1	Nto1p	0.280
FKH2	Fkh2p	0.254
CDC6	Cdc6p	0.230
SUM1	Sum1p	0.215
MIG2	Mig2p	0.214	Yeast
HHT1	Hht1p	0.197
HOS3	Hos3p	0.188
SIR2	Sir2p	0.175
SET3	Set3p	0.174
UME6	Ume6p	0.132
EAF3	Eaf3p	0.127
RCO1	Rco1p	0.122
AFT1	Aft1p	0.120
HHO1	Hho1p	0.120
ROX1	Rox1p	0.119
ASH1	Ash1p	0.113
SWI1	Swi1p	0.109
MIG1	Mig1p	0.100	Yeast
HOS4	Hos4p	0.094
SLX8	Slx8p	0.088
ZAP1	Zap1p	0.086
SNT1	Snt1p	0.082
RAP1	Rap1p	0.081
MCM3	Mcm3p	0.079
DEF1	Def1p	0.077
MMS21	Mms21p	0.074
HXT3	Hxt3p	0.073
KIC1	Kic1p	0.071
YKR075C	hypothetical protein	0.070
MIG3	Mig3p	0.068	Yeast
YML082W	hypothetical protein	0.068
AGP2	Agp2p	0.066
NRG1	Nrg1p	0.066	Yeast
SLX5	Slx5p	0.065
SIR4	Sir4p	0.061
IRA2	Ira2p	0.059
HHF2	Hhf2p	0.058
SAN1	San1p	0.057
YLR455W	hypothetical protein	0.053
RAD51	Rad51p	0.051
IXR1	Ixr1p	0.051
YGR126W	hypothetical protein	0.048
YKU70	Yku70p	0.048
HOS2	Hos2p	0.048	Yeast
YLR278C	hypothetical protein	0.047
LYS5	Lys5p	0.046
HAL5	Hal5p	0.046
RXT3	Rxt3p	0.044
YOR390W	hypothetical protein	0.044
OPI1	Opi1p	0.044
CAT8	Cat8p	0.041
STE7	Ste7p	0.040
SRP54	Srp54p	0.039
SIW14	Siw14p	0.039
RGT1	Rgt1p	0.038
HO	Hop	0.038
HDA3	Hda3p	0.037
TYW1	Tyw1p	0.037
DOT6	Dot6p	0.036
STH1	Sth1p	0.036
HIR2	Hir2p	0.036
YMR259C	hypothetical protein	0.036
SFL1	Sfl1p	0.035
MPT5	Mpt5p	0.034	Yeast
TRA1	Tra1p	0.034
YDL156W	hypothetical protein	0.034
YCL042W	hypothetical protein	0.034
NDD1	Ndd1p	0.033
ATG15	Atg15p	0.033
DED1	Ded1p	0.033
HDA2	Hda2p	0.033
UBP8	Ubp8p	0.033
TBS1	Tbs1p	0.032
IFH1	Ifh1p	0.031
YKL187C	hypothetical protein	0.031
HMO1	Hmo1p	0.030
MOT1	Mot1p	0.029
SNA4	Sna4p	0.029
RMA1	Rma1p	0.028
GAT2	Gat2p	0.028
GCR2	Gcr2p	0.028
ARP8	Arp8p	0.027
NFI1	Nfi1p	0.027
MET28	Met28p	0.027
GIC1	Gic1p	0.026
DEP1	Dep1p	0.026
IRC23	Irc23p	0.026
POG1	Pog1p	0.026
NUP1	Nup1p	0.026
HXT1	Hxt1p	0.025
RTF1	Rtf1p	0.025
CTK3	Ctk3p	0.025
SNF5	Snf5p	0.025
PHO12	Pho12p	0.025
HHT2	Hht2p	0.025
PRI1	Pri1p	0.025
CLB1	Clb1p	0.024
NAB3	Nab3p	0.024
WHI3	Whi3p	0.024
RAX1	Rax1p	0.024
HSH155	Hsh155p	0.024
YPL014W	hypothetical protein	0.023
MTR10	Mtr10p	0.023
RAD28	Rad28p	0.023
MCM7	Mcm7p	0.022
RAD52	Rad52p	0.022
CTR9	Ctr9p	0.022
NUP157	Nup157p	0.022
VAC17	Vac17p	0.022
YLR264C-A	hypothetical protein	0.022
YPR157W	hypothetical protein	0.022
CUP1-1	Cup1-1p	0.022
SOR2	Sor2p	0.022
CAF40	Caf40p	0.022
FMP52	Fmp52p	0.021
SAP190	Sap190p	0.021
SRD1	Srd1p	0.021
HST1	Hst1p	0.021	Yeast
FAA2	Faa2p	0.021
RIM101	Rim101p	0.021	Yeast
ZDS1	Zds1p	0.021
YLR162W	hypothetical protein	0.021
SCT1	Sct1p	0.020
MEC1	Mec1p	0.020
RRN5	Rrn5p	0.020
TOF2	Tof2p	0.020
YLR057W	hypothetical protein	0.020
RIM13	Rim13p	0.020
HST3	Hst3p	0.020	Yeast
SAK1	Sak1p	0.020
PUT4	Put4p	0.020
GTO3	Gto3p	0.020
RPI1	Rpi1p	0.020
CHD1	Chd1p	0.020
VPS41	Vps41p	0.019
SUR1	Sur1p	0.019
YCL021W-A	hypothetical protein	0.019
YBL081W	hypothetical protein	0.019
YIR042C	hypothetical protein	0.019
MET2	Met2p	0.019
IKI1	Iki1p	0.019
NHP6A	Nhp6ap	0.019
VHS1	Vhs1p	0.019
IOC4	Ioc4p	0.019
IES2	Ies2p	0.019
MOB1	Mob1p	0.019
ART5	Art5p	0.019
POP2	Pop2p	0.019
WAR1	War1p	0.019
CPR1	Cpr1p	0.018
ICS2	Ics2p	0.018
PRS2	Prs2p	0.018
ATG13	Atg13p	0.018
RPR2	Rpr2p	0.018
SMP1	Smp1p	0.018
EDC1	Edc1p	0.018
RAD14	Rad14p	0.018
LEU2	Leu2p	0.018
BSC2	Bsc2p	0.018
GIS4	Gis4p	0.018
YOL038C-A	hypothetical protein	0.018
SPS4	Sps4p	0.018
MRS6	Mrs6p	0.017
ADH7	Adh7p	0.017
CDC13	Cdc13p	0.017
RAD16	Rad16p	0.017
ARG8	Arg8p	0.017
YBL029W	hypothetical protein	0.017
PCL2	Pcl2p	0.017
YPR013C	hypothetical protein	0.017	Yeast
MSI1	Msi1p	0.017
HPF1	Hpf1p	0.017
YAT1	Yat1p	0.017
SPL2	Spl2p	0.016
QDR3	Qdr3p	0.016
ARP10	Arp10p	0.016
MET4	Met4p	0.016
FCP1	Fcp1p	0.016
TOS3	Tos3p	0.016
FMT1	Fmt1p	0.016
AQR1	Aqr1p	0.016
RAX2	Rax2p	0.016
INO4	Ino4p	0.016
SPT10	Spt10p	0.016
SRS2	Srs2p	0.016
YGR168C	hypothetical protein	0.016
FPK1	Fpk1p	0.016
YBR013C	hypothetical protein	0.016
CAF120	Caf120p	0.016
STR3	Str3p	0.016
YLR297W	hypothetical protein	0.015
MGA2	Mga2p	0.015
RIF1	Rif1p	0.015
YGR035C	hypothetical protein	0.015
ATF1	Atf1p	0.015
NRG2	Nrg2p	0.015
YAR068W	hypothetical protein	0.015
YIR035C	hypothetical protein	0.015
RGS2	Rgs2p	0.015
PSK2	Psk2p	0.015
MER1	Mer1p	0.015
RIB2	Rib2p	0.015
SKS1	Sks1p	0.015
STL1	Stl1p	0.015
ROG3	Rog3p	0.015
SGF29	Sgf29p	0.015
AUA1	Aua1p	0.015
ARP4	Arp4p	0.015
SUT1	Sut1p	0.015
NBA1	Nba1p	0.015
CTK1	Ctk1p	0.015
GIS3	Gis3p	0.015
BUD4	Bud4p	0.015
MCM10	Mcm10p	0.015
NRM1	Nrm1p	0.015
SHE2	She2p	0.015
MDJ2	Mdj2p	0.015
PLB3	Plb3p	0.015
KIN3	Kin3p	0.015
ADY2	Ady2p	0.015
IZH4	Izh4p	0.014
PYK2	Pyk2p	0.014
STE4	Ste4p	0.014
BUR6	Bur6p	0.014
AST1	Ast1p	0.014
BAP2	Bap2p	0.014
HSF1	Hsf1p	0.014
HOT1	Hot1p	0.014
STB5	Stb5p	0.014
ARE2	Are2p	0.014
CPD1	Cpd1p	0.014
YKR096W	hypothetical protein	0.014
ZPS1	Zps1p	0.014
ASF2	Asf2p	0.014
MSG5	Msg5p	0.014
SSK2	Ssk2p	0.014
TIP1	Tip1p	0.014
VHR1	Vhr1p	0.014
YER186C	hypothetical protein	0.014
FZF1	Fzf1p	0.014	Yeast
URA3	Ura3p	0.014
HOR2	Hor2p	0.014
PMA2	Pma2p	0.014
WSS1	Wss1p	0.014
YML003W	hypothetical protein	0.014
ENT5	Ent5p	0.014
QDR1	Qdr1p	0.014
ATP6	Atp6p	0.014
APE3	Ape3p	0.014
YOX1	Yox1p	0.014
ICT1	Ict1p	0.014
IZH3	Izh3p	0.014
YMR295C	hypothetical protein	0.014
YLR419W	hypothetical protein	0.014
SWM2	Swm2p	0.014
PTR2	Ptr2p	0.013
PUT1	Put1p	0.013
YLR173W	hypothetical protein	0.013
YOL013W-A	hypothetical protein	0.013
KTR5	Ktr5p	0.013
COS10	Cos10p	0.013
TRS23	Trs23p	0.013
ULP2	Ulp2p	0.013
RNP1	Rnp1p	0.013
YNL035C	hypothetical protein	0.013
FRM2	Frm2p	0.013
YGR017W	hypothetical protein	0.013
YJR115W	hypothetical protein	0.013
GAL4	Gal4p	0.013
UBP1	Ubp1p	0.013
YAR066W	hypothetical protein	0.013
BSC1	Bsc1p	0.013
BDF2	Bdf2p	0.013
CUP1-2	Cup1-2p	0.013
GDS1	Gds1p	0.013
ACA1	Aca1p	0.013
ICY1	Icy1p	0.013
AAD6	Aad6p	0.013
HTB1	Htb1p	0.013
BOP3	Bop3p	0.013
TAH11	Tah11p	0.013
HUG1	Hug1p	0.013
MF(ALPHA)2	Mf(alpha)2p	0.013
LCL1	Lcl1p	0.013
AVT6	Avt6p	0.013
CHA1	Cha1p	0.013
URB2	Urb2p	0.013
RIA1	Ria1p	0.013
UBP5	Ubp5p	0.013
YOR385W	hypothetical protein	0.013
GIP2	Gip2p	0.013
RAD34	Rad34p	0.013
YDR506C	hypothetical protein	0.013
DNF3	Dnf3p	0.013
GAL80	Gal80p	0.013
DBP1	Dbp1p	0.013
HMS1	Hms1p	0.012
ELP4	Elp4p	0.012
YOR012W	hypothetical protein	0.012
YLR042C	hypothetical protein	0.012
PSR1	Psr1p	0.012
MHT1	Mht1p	0.012
SRT1	Srt1p	0.012
YNL058C	hypothetical protein	0.012
AQY1	Aqy1p	0.012
RIM8	Rim8p	0.012
SGF73	Sgf73p	0.012
ASE1	Ase1p	0.012
GPB2	Gpb2p	0.012
RIF2	Rif2p	0.012
TYE7	Tye7p	0.012
MOT3	Mot3p	0.012	Yeast
CSR2	Csr2p	0.012
ALT2	Alt2p	0.012
HRP1	Hrp1p	0.012
KRE29	Kre29p	0.012
MUM3	Mum3p	0.012
YDR034W-B	hypothetical protein	0.012
MOD5	Mod5p	0.012
PTP3	Ptp3p	0.012
RUP1	Rup1p	0.012
YJL107C	hypothetical protein	0.012
YAL064W	hypothetical protein	0.012
PAC1	Pac1p	0.012
KNH1	Knh1p	0.012
SAD1	Sad1p	0.012
STP2	Stp2p	0.012	Yeast
ATO2	Ato2p	0.012
YPK3	Ypk3p	0.012
YCR087C-A	hypothetical protein	0.012
YJL160C	hypothetical protein	0.012
LEU3	Leu3p	0.012
RMD5	Rmd5p	0.012
TRK1	Trk1p	0.012
CCH1	Cch1p	0.012
PRM4	Prm4p	0.012
TFC3	Tfc3p	0.012
MDS3	Mds3p	0.012
YEL073C	hypothetical protein	0.012
HEF3	Hef3p	0.012
SIT1	Sit1p	0.012
SPT20	Spt20p	0.012
REE1	Ree1p	0.012
TPC1	Tpc1p	0.012
EXO1	Exo1p	0.012
YAL037C-A	hypothetical protein	0.012
SBE22	Sbe22p	0.012
LRO1	Lro1p	0.012
COX19	Cox19p	0.012
ARN2	Arn2p	0.012
RRN9	Rrn9p	0.012
TIR3	Tir3p	0.012
TIS11	Tis11p	0.012
KES1	Kes1p	0.012
GLG2	Glg2p	0.012
YER034W	hypothetical protein	0.012
ZRT1	Zrt1p	0.012
YGL015C	hypothetical protein	0.012
DHH1	Dhh1p	0.011
BIT61	Bit61p	0.011
SFC1	Sfc1p	0.011
YMR317W	hypothetical protein	0.011
BNA4	Bna4p	0.011
YKR041W	hypothetical protein	0.011
DIC1	Dic1p	0.011
YPR096C	hypothetical protein	0.011
YKR045C	hypothetical protein	0.011
REB1	Reb1p	0.011
SIZ1	Siz1p	0.011	Yeast
DAS2	Das2p	0.011
YTA6	Yta6p	0.011
YPL168W	hypothetical protein	0.011
PCL5	Pcl5p	0.011
YPR153W	hypothetical protein	0.011
AAD15	Aad15p	0.011
ZWF1	Zwf1p	0.011
YDL218W	hypothetical protein	0.011
TDP1	Tdp1p	0.011
SET2	Set2p	0.011
RDS2	Rds2p	0.011
DIA1	Dia1p	0.011
LGE1	Lge1p	0.011
IRC8	Irc8p	0.011
ATG29	Atg29p	0.011
DFG16	Dfg16p	0.011
MF(ALPHA)1	Mf(alpha)1p	0.011
VPS75	Vps75p	0.011
DIF1	Dif1p	0.011
YLR460C	hypothetical protein	0.011
MSN2	Msn2p	0.011	Yeast
MDN1	Mdn1p	0.011
YGL006W-A	hypothetical protein	0.011
KIN4	Kin4p	0.011
RLM1	Rlm1p	0.011
UTP18	Utp18p	0.011
CTS1	Cts1p	0.011
GDH3	Gdh3p	0.011
PTC2	Ptc2p	0.011
YPL216W	hypothetical protein	0.011
TOS8	Tos8p	0.011
SET4	Set4p	0.011
YDR524W-C	hypothetical protein	0.011
YLR040C	hypothetical protein	0.011
YNR063W	hypothetical protein	0.011
FRT1	Frt1p	0.011
YMR253C	hypothetical protein	0.011
ERT1	Ert1p	0.011
FRE4	Fre4p	0.011
TKL2	Tkl2p	0.011
HOR7	Hor7p	0.011
YJL181W	hypothetical protein	0.011
CAM1	Cam1p	0.011
COS12	Cos12p	0.011
YNL067W-B	hypothetical protein	0.011
PFK27	Pfk27p	0.011
GPD2	Gpd2p	0.011
RGD2	Rgd2p	0.011
ICS3	Ics3p	0.011
YML100W-A	hypothetical protein	0.010
ENA5	Ena5p	0.010
YLR363W-A	hypothetical protein	0.010
THP1	Thp1p	0.010
MDM1	Mdm1p	0.010
SCM4	Scm4p	0.010
FRE5	Fre5p	0.010
YER064C	hypothetical protein	0.010
YAP5	Yap5p	0.010
YNR062C	hypothetical protein	0.010
YGL235W	hypothetical protein	0.010
YDL109C	hypothetical protein	0.010
PDC6	Pdc6p	0.010
MFA2	Mfa2p	0.010
MBR1	Mbr1p	0.010
XBP1	Xbp1p	0.010
EPL1	Epl1p	0.010
VID24	Vid24p	0.010
CIN5	Cin5p	0.010
RSB1	Rsb1p	0.010
GLN3	Gln3p	0.010
YLR281C	hypothetical protein	0.010
RTT105	Rtt105p	0.010
YPL257W	hypothetical protein	0.010
ALD4	Ald4p	0.010
DAL81	Dal81p	0.010
YNL033W	hypothetical protein	0.010
EDS1	Eds1p	0.010
BDS1	Bds1p	0.010
YPL067C	hypothetical protein	0.010
KIN1	Kin1p	0.010
APJ1	Apj1p	0.010
AQY2	Aqy2p	0.010
YPR027C	hypothetical protein	0.010
PRP46	Prp46p	0.010
YJR120W	hypothetical protein	0.010
YHR035W	hypothetical protein	0.010
YER130C	hypothetical protein	0.010	Yeast