IMP

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Saccharomyces cerevisiae

29 genes annotated in yeast

dna damage checkpoint

A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna damage checkpoint"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dna damage checkpoint" (in gray)

Name	Description	Probability	Func Analog Organism
PSY2	Psy2p	0.846
RAD53	Rad53p	0.841
RAD9	Rad9p	0.661
POL30	Pol30p	0.634
MEC1	Mec1p	0.589	Human Fly
BMH1	Bmh1p	0.439
PPH21	Pph21p	0.435	Yeast
MCM5	Mcm5p	0.359
RPO26	Rpo26p	0.285
SPT5	Spt5p	0.276
RAD17	Rad17p	0.233
TOR1	Tor1p	0.230
RGC1	Rgc1p	0.191
MRC1	Mrc1p	0.183
TCO89	Tco89p	0.163
TIP41	Tip41p	0.157
FPK1	Fpk1p	0.155
CKA2	Cka2p	0.152
MCM10	Mcm10p	0.135
RFA1	Rfa1p	0.128
PSF1	Psf1p	0.121
VAC17	Vac17p	0.120
HTB1	Htb1p	0.116
SUM1	Sum1p	0.113
MCM2	Mcm2p	0.111
AHP1	Ahp1p	0.108
PDS1	Pds1p	0.107
HRK1	Hrk1p	0.106	Yeast
PPH3	Pph3p	0.103
SIT4	Sit4p	0.102
PTK2	Ptk2p	0.095	Yeast
TOF1	Tof1p	0.089
MCM4	Mcm4p	0.089
DBF4	Dbf4p	0.087
THO2	Tho2p	0.087
SNF1	Snf1p	0.086
DPB2	Dpb2p	0.085
DPB11	Dpb11p	0.085
MUS81	Mus81p	0.084
RRD1	Rrd1p	0.084
RAD52	Rad52p	0.082
SRS2	Srs2p	0.082
YPL260W	hypothetical protein	0.080
RPB2	Rpb2p	0.079
PLC1	Plc1p	0.076
CKA1	Cka1p	0.076
REG1	Reg1p	0.075
SCS2	Scs2p	0.075
UBP8	Ubp8p	0.073
HAL5	Hal5p	0.070	Yeast
EAF1	Eaf1p	0.068
MMS22	Mms22p	0.067
CRZ1	Crz1p	0.067
PAM1	Pam1p	0.066
PEX10	Pex10p	0.065
GBP2	Gbp2p	0.064
SUR1	Sur1p	0.063
MCM3	Mcm3p	0.063	Fly
CDC6	Cdc6p	0.063
SGS1	Sgs1p	0.061
RAD18	Rad18p	0.060
KIN82	Kin82p	0.059
YLR257W	hypothetical protein	0.059
ASF1	Asf1p	0.058
BSC2	Bsc2p	0.058
PDR15	Pdr15p	0.057
SCH9	Sch9p	0.057
CTK1	Ctk1p	0.057
ROD1	Rod1p	0.056
HPR1	Hpr1p	0.056
CWC2	Cwc2p	0.055
RTS1	Rts1p	0.055
DED1	Ded1p	0.054
DSK2	Dsk2p	0.052
ZEO1	Zeo1p	0.052
HOG1	Hog1p	0.051	Mouse
SAK1	Sak1p	0.050
RPB11	Rpb11p	0.049
RRM3	Rrm3p	0.049
SOK1	Sok1p	0.049
MMS1	Mms1p	0.049
RAD24	Rad24p	0.047
PEX22	Pex22p	0.046
CAK1	Cak1p	0.046
RPB10	Rpb10p	0.046
PRP45	Prp45p	0.046
SIR2	Sir2p	0.045
PDE2	Pde2p	0.045
RTG3	Rtg3p	0.045
HOP1	Hop1p	0.044
CHK1	Chk1p	0.044
DNA2	Dna2p	0.043
MCM6	Mcm6p	0.043
DDC1	Ddc1p	0.043
PPH22	Pph22p	0.043	Yeast
DIA2	Dia2p	0.042
RTS3	Rts3p	0.041
CLB6	Clb6p	0.041
CKS1	Cks1p	0.040
ZIP1	Zip1p	0.040
PPZ1	Ppz1p	0.039
CTF4	Ctf4p	0.039
YGL101W	hypothetical protein	0.038
PCL9	Pcl9p	0.038
HAA1	Haa1p	0.037
HAC1	Hac1p	0.037
MGS1	Mgs1p	0.037
ALD6	Ald6p	0.037
YLR177W	hypothetical protein	0.037
RAD59	Rad59p	0.037
SIA1	Sia1p	0.036
SDS22	Sds22p	0.036
MMT2	Mmt2p	0.036
CDC55	Cdc55p	0.035
HTA1	Hta1p	0.035	Human
TSA2	Tsa2p	0.035
GAL7	Gal7p	0.035
RED1	Red1p	0.033
CKB1	Ckb1p	0.033
YRR1	Yrr1p	0.033
RMI1	Rmi1p	0.032
POL3	Pol3p	0.032
PSY4	Psy4p	0.032
SLD2	Sld2p	0.032
PAT1	Pat1p	0.032
KSP1	Ksp1p	0.032	Yeast
YPK1	Ypk1p	0.031
SAE2	Sae2p	0.031
MMS21	Mms21p	0.031
YJU2	Yju2p	0.030
ELG1	Elg1p	0.030
SKY1	Sky1p	0.030
IZH3	Izh3p	0.030
SPT4	Spt4p	0.030
RIF1	Rif1p	0.029
YBR287W	hypothetical protein	0.029
PAH1	Pah1p	0.029
SAP155	Sap155p	0.029
SSN3	Ssn3p	0.029	Fly
AIM20	Aim20p	0.029
IME2	Ime2p	0.028
CCR4	Ccr4p	0.028
CDC15	Cdc15p	0.028
SNF3	Snf3p	0.027
KOG1	Kog1p	0.027
AZF1	Azf1p	0.027
YNL134C	hypothetical protein	0.027
CDC13	Cdc13p	0.026
TEL1	Tel1p	0.026
DIN7	Din7p	0.026
ADE17	Ade17p	0.026
CSM4	Csm4p	0.026
TOR2	Tor2p	0.026
MKS1	Mks1p	0.026
SWI4	Swi4p	0.025
NOP10	Nop10p	0.025
CLF1	Clf1p	0.025
RAD55	Rad55p	0.025
MBF1	Mbf1p	0.024
YJR061W	hypothetical protein	0.024
NUR1	Nur1p	0.024
POL1	Pol1p	0.024
HTA2	Hta2p	0.024	Human
AIR2	Air2p	0.024
MAM1	Mam1p	0.024
TCP1	Tcp1p	0.024
ACB1	Acb1p	0.023
DUN1	Dun1p	0.023
STE7	Ste7p	0.023
UBC13	Ubc13p	0.023
ESS1	Ess1p	0.022
FAA2	Faa2p	0.022
ADH2	Adh2p	0.022
YML131W	hypothetical protein	0.022
CAM1	Cam1p	0.022
SKM1	Skm1p	0.022
ACC1	Acc1p	0.022
SKI8	Ski8p	0.021
NRM1	Nrm1p	0.021
YIL151C	hypothetical protein	0.021
SKS1	Sks1p	0.021	Yeast
YCH1	Ych1p	0.021
HUL5	Hul5p	0.021
YKR075C	hypothetical protein	0.021
PDS5	Pds5p	0.021
CSM3	Csm3p	0.021
YLR264C-A	hypothetical protein	0.021
PTC2	Ptc2p	0.021
UBC4	Ubc4p	0.021
CTK3	Ctk3p	0.020
REC8	Rec8p	0.020
CLB3	Clb3p	0.020
FAR11	Far11p	0.020
TIF4632	Tif4632p	0.020
RLF2	Rlf2p	0.020
PRR2	Prr2p	0.020	Yeast
CMK2	Cmk2p	0.020	Yeast
CYC8	Cyc8p	0.020
ESP1	Esp1p	0.020
SRD1	Srd1p	0.020
MPT5	Mpt5p	0.020
YGR205W	hypothetical protein	0.019
VHS1	Vhs1p	0.019	Yeast
DTR1	Dtr1p	0.019
CDC16	Cdc16p	0.019
RPO31	Rpo31p	0.019
TYE7	Tye7p	0.019
AHC1	Ahc1p	0.019
NHP6A	Nhp6ap	0.019
SKO1	Sko1p	0.019
GIS4	Gis4p	0.019
RCK2	Rck2p	0.019	Yeast
PIN4	Pin4p	0.019
MDS3	Mds3p	0.019
FKH1	Fkh1p	0.019
DPB4	Dpb4p	0.019
YLR162W	hypothetical protein	0.019
TRX2	Trx2p	0.019
PHO87	Pho87p	0.019
SPS22	Sps22p	0.019
ART10	Art10p	0.018
YDR338C	hypothetical protein	0.018
URN1	Urn1p	0.018
CTF8	Ctf8p	0.018
MSG5	Msg5p	0.018
TPI1	Tpi1p	0.018
NCE103	Nce103p	0.018
RFA2	Rfa2p	0.018	Human
RPB7	Rpb7p	0.018
CHA1	Cha1p	0.018
HDA1	Hda1p	0.018
SUS1	Sus1p	0.018
RAD10	Rad10p	0.017
CHL1	Chl1p	0.017
PCH2	Pch2p	0.017
RHO1	Rho1p	0.017
URA3	Ura3p	0.017
YIR014W	hypothetical protein	0.017
YOL038C-A	hypothetical protein	0.017
IPT1	Ipt1p	0.017
RAD27	Rad27p	0.017
HST3	Hst3p	0.017
HO	Hop	0.017
FAR3	Far3p	0.017
YCR102C	hypothetical protein	0.017
RNR2	Rnr2p	0.017
LCD1	Lcd1p	0.017
PEX2	Pex2p	0.017
SPT8	Spt8p	0.017
ARG8	Arg8p	0.017
YOR385W	hypothetical protein	0.017
LEU2	Leu2p	0.016
MYO3	Myo3p	0.016
HDA2	Hda2p	0.016
ZDS2	Zds2p	0.016
ALY1	Aly1p	0.016
SGV1	Sgv1p	0.016
IML1	Iml1p	0.016
IMA4	Ima4p	0.016
CTR9	Ctr9p	0.016
FMT1	Fmt1p	0.016
SAP4	Sap4p	0.016
ICY1	Icy1p	0.016
TEX1	Tex1p	0.016
YAR068W	hypothetical protein	0.016
HFM1	Hfm1p	0.016
EST2	Est2p	0.016
YDL157C	hypothetical protein	0.015
GIC1	Gic1p	0.015
CLB1	Clb1p	0.015
YLR012C	hypothetical protein	0.015
SCD6	Scd6p	0.015
YBL081W	hypothetical protein	0.015
ARE2	Are2p	0.015
CLG1	Clg1p	0.015
GDS1	Gds1p	0.015
SDC1	Sdc1p	0.015
UBP11	Ubp11p	0.015
CMK1	Cmk1p	0.015	Yeast
CLB5	Clb5p	0.015
WSS1	Wss1p	0.015
CUP1-1	Cup1-1p	0.015
URA6	Ura6p	0.015
GUT1	Gut1p	0.015
YMR102C	hypothetical protein	0.015
RPL41A	Rpl41ap	0.015
YDL183C	hypothetical protein	0.015
SVL3	Svl3p	0.015
GPD2	Gpd2p	0.015
AKL1	Akl1p	0.015
NOP6	Nop6p	0.015
ZPS1	Zps1p	0.015
TRR1	Trr1p	0.015
SPE3	Spe3p	0.015
GLC7	Glc7p	0.015
CLB2	Clb2p	0.015
MAL33	Mal33p	0.015
PTR2	Ptr2p	0.015
FAR10	Far10p	0.015
APC5	Apc5p	0.014
YPL014W	hypothetical protein	0.014
POG1	Pog1p	0.014
POL12	Pol12p	0.014
ECM11	Ecm11p	0.014
CNB1	Cnb1p	0.014
RCK1	Rck1p	0.014	Yeast
LCB4	Lcb4p	0.014
FMP52	Fmp52p	0.014
SRO77	Sro77p	0.014
MER1	Mer1p	0.014
AAD6	Aad6p	0.014
FCY22	Fcy22p	0.014
SPL2	Spl2p	0.014
CDC7	Cdc7p	0.014
VHR1	Vhr1p	0.014
ECO1	Eco1p	0.014
DOG1	Dog1p	0.014
ATP6	Atp6p	0.014
UBP3	Ubp3p	0.014
PUF2	Puf2p	0.014
PHO3	Pho3p	0.014
YGL235W	hypothetical protein	0.014
ARO10	Aro10p	0.014
SSP1	Ssp1p	0.014
IRC15	Irc15p	0.014
TGL4	Tgl4p	0.014
PCL1	Pcl1p	0.013
PRP28	Prp28p	0.013
YNL144C	hypothetical protein	0.013
SSK1	Ssk1p	0.013
YOL013W-A	hypothetical protein	0.013
SLD5	Sld5p	0.013
YNL234W	hypothetical protein	0.013
AUA1	Aua1p	0.013
STE4	Ste4p	0.013
PDI1	Pdi1p	0.013
UBP5	Ubp5p	0.013
SPO16	Spo16p	0.013
IME1	Ime1p	0.013
FOB1	Fob1p	0.013
PMA2	Pma2p	0.013
PIL1	Pil1p	0.013
GLN1	Gln1p	0.013
YLR001C	hypothetical protein	0.013
YPR013C	hypothetical protein	0.013
OPT2	Opt2p	0.013
MSN4	Msn4p	0.013
HSL1	Hsl1p	0.013
SEC16	Sec16p	0.013
CAB3	Cab3p	0.013
TSC3	Tsc3p	0.013
PIR1	Pir1p	0.013
PFK27	Pfk27p	0.013
SPO13	Spo13p	0.013
REV7	Rev7p	0.013
SPP381	Spp381p	0.013
GPB2	Gpb2p	0.013
PUF4	Puf4p	0.013
REV1	Rev1p	0.013
YAR066W	hypothetical protein	0.013
CPD1	Cpd1p	0.013
YPR157W	hypothetical protein	0.013
NRG2	Nrg2p	0.013
YOL014W	hypothetical protein	0.013
ARP10	Arp10p	0.013
BMH2	Bmh2p	0.012
HPF1	Hpf1p	0.012
SUT1	Sut1p	0.012
RFC5	Rfc5p	0.012
RGI2	Rgi2p	0.012
SGN1	Sgn1p	0.012
GAL83	Gal83p	0.012
MF(ALPHA)2	Mf(alpha)2p	0.012
OCH1	Och1p	0.012
SWC7	Swc7p	0.012
APT2	Apt2p	0.012
YOR060C	hypothetical protein	0.012
YHB1	Yhb1p	0.012
SUC2	Suc2p	0.012
RRN5	Rrn5p	0.012
BSC1	Bsc1p	0.012
URA2	Ura2p	0.012
YLR455W	hypothetical protein	0.012
DIF1	Dif1p	0.012
YLR042C	hypothetical protein	0.012
YIR042C	hypothetical protein	0.012
YBL104C	hypothetical protein	0.012
HUR1	Hur1p	0.012
KCS1	Kcs1p	0.012
HCM1	Hcm1p	0.012
YNL033W	hypothetical protein	0.012
HEM1	Hem1p	0.012
PRP22	Prp22p	0.012
PPE1	Ppe1p	0.012
HXT3	Hxt3p	0.012
YBR013C	hypothetical protein	0.012
BCK2	Bck2p	0.012
BIT61	Bit61p	0.012
INO1	Ino1p	0.012
NUT2	Nut2p	0.012
TAX4	Tax4p	0.012
BIO2	Bio2p	0.012
YAL064W	hypothetical protein	0.012
YMR122W-A	hypothetical protein	0.012
SAE3	Sae3p	0.012
TIR3	Tir3p	0.012
UTR1	Utr1p	0.012
LRO1	Lro1p	0.012
YKR041W	hypothetical protein	0.012
AQY2	Aqy2p	0.012
VHS2	Vhs2p	0.012
APN1	Apn1p	0.011
YJL160C	hypothetical protein	0.011
ADR1	Adr1p	0.011
PTI1	Pti1p	0.011
ICS2	Ics2p	0.011
YPS1	Yps1p	0.011
PCL8	Pcl8p	0.011
MBR1	Mbr1p	0.011
YLR040C	hypothetical protein	0.011
RPN4	Rpn4p	0.011
YEA6	Yea6p	0.011
FCY21	Fcy21p	0.011
LEU1	Leu1p	0.011
YNL190W	hypothetical protein	0.011
YPR096C	hypothetical protein	0.011
SNU66	Snu66p	0.011
PYC1	Pyc1p	0.011
SCM4	Scm4p	0.011
YML003W	hypothetical protein	0.011
YGR035C	hypothetical protein	0.011
DCC1	Dcc1p	0.011
PRP19	Prp19p	0.011
YBL044W	hypothetical protein	0.011
PHD1	Phd1p	0.011
EOS1	Eos1p	0.011
YPR027C	hypothetical protein	0.011
ALO1	Alo1p	0.011
YJR120W	hypothetical protein	0.011
HHT2	Hht2p	0.011
SPO77	Spo77p	0.011
SNT1	Snt1p	0.011
CRR1	Crr1p	0.011
MSH6	Msh6p	0.011
PYC2	Pyc2p	0.011
XRS2	Xrs2p	0.011
SIN4	Sin4p	0.011
YOL131W	hypothetical protein	0.011
HCH1	Hch1p	0.011
SMP1	Smp1p	0.011
ERR3	Err3p	0.011
ROX1	Rox1p	0.011
GIS3	Gis3p	0.011
ENA5	Ena5p	0.011
RPS6B	Rps6bp	0.011
HHO1	Hho1p	0.011
YER186C	hypothetical protein	0.011
FRA1	Fra1p	0.011
GPD1	Gpd1p	0.011
TRR2	Trr2p	0.011
THP3	Thp3p	0.011
YER039C-A	hypothetical protein	0.011
RPI1	Rpi1p	0.011
REE1	Ree1p	0.011
SPS4	Sps4p	0.011
YNL024C	hypothetical protein	0.011
PRM4	Prm4p	0.011
YAL037C-A	hypothetical protein	0.011
YHR097C	hypothetical protein	0.011
IRC8	Irc8p	0.011
ZRT1	Zrt1p	0.011
YOR365C	hypothetical protein	0.011
GSC2	Gsc2p	0.011
SIS2	Sis2p	0.011
KNH1	Knh1p	0.011
YNL067W-B	hypothetical protein	0.011
SIP1	Sip1p	0.011
OLE1	Ole1p	0.011
RSB1	Rsb1p	0.011
RTT105	Rtt105p	0.011
NTA1	Nta1p	0.010
YGL006W-A	hypothetical protein	0.010
VID24	Vid24p	0.010
NFI1	Nfi1p	0.010
YPR153W	hypothetical protein	0.010
YMR317W	hypothetical protein	0.010
RNP1	Rnp1p	0.010
MF(ALPHA)1	Mf(alpha)1p	0.010
SLX4	Slx4p	0.010
YBR235W	hypothetical protein	0.010
HSP150	Hsp150p	0.010
DBP1	Dbp1p	0.010
SMX3	Smx3p	0.010
YJL181W	hypothetical protein	0.010
GAL4	Gal4p	0.010
KKQ8	Kkq8p	0.010	Yeast
CMP2	Cmp2p	0.010
REG2	Reg2p	0.010
CTS1	Cts1p	0.010
AIF1	Aif1p	0.010
DAK2	Dak2p	0.010
YKL070W	hypothetical protein	0.010
CWP1	Cwp1p	0.010
UPS3	Ups3p	0.010
YHR035W	hypothetical protein	0.010
MNR2	Mnr2p	0.010
PHM6	Phm6p	0.010
NDD1	Ndd1p	0.010
YLR412C-A	hypothetical protein	0.010
DUR1,2	Dur1,2p	0.010
YOR387C	hypothetical protein	0.010
YPL067C	hypothetical protein	0.010
YNR071C	hypothetical protein	0.010
TRK1	Trk1p	0.010
COS111	Cos111p	0.010
YPL272C	hypothetical protein	0.010
MFA2	Mfa2p	0.010
BNA4	Bna4p	0.010
YLR152C	hypothetical protein	0.010
MNN4	Mnn4p	0.010
RPA135	Rpa135p	0.010
PPQ1	Ppq1p	0.010	Yeast
BDS1	Bds1p	0.010
DIC1	Dic1p	0.010
CDC20	Cdc20p	0.010