IMP

Process View

Saccharomyces cerevisiae

30 genes annotated in yeast

regulation of proteasomal ubiquitin dependent protein catabolic process

Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of proteasomal ubiquitin dependent protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of proteasomal ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
RPT6	Rpt6p	0.944
CDC20	Cdc20p	0.928
MAD2	Mad2p	0.848
RPT1	Rpt1p	0.795
RAD23	Rad23p	0.764	Human
RPT3	Rpt3p	0.763
PPH21	Pph21p	0.701
RPT4	Rpt4p	0.672
BUB3	Bub3p	0.660	Worm Fly
ECM29	Ecm29p	0.629
RPN10	Rpn10p	0.619
RPT2	Rpt2p	0.539
CDC55	Cdc55p	0.503
MLC1	Mlc1p	0.485
YPI1	Ypi1p	0.478
PRE2	Pre2p	0.445
PRE1	Pre1p	0.436
RPN9	Rpn9p	0.435
RPN7	Rpn7p	0.425
CDC16	Cdc16p	0.408	Fly
RPN11	Rpn11p	0.338	Fly
CTF13	Ctf13p	0.337
RPN12	Rpn12p	0.325
PPH22	Pph22p	0.319
CDC26	Cdc26p	0.316
PRE10	Pre10p	0.283
PRE6	Pre6p	0.266
AFT1	Aft1p	0.262
DSK2	Dsk2p	0.260
RPN6	Rpn6p	0.255
GLC7	Glc7p	0.242
SLK19	Slk19p	0.241
UBC13	Ubc13p	0.239
RPN1	Rpn1p	0.232
RPT5	Rpt5p	0.219
PSH1	Psh1p	0.203
CDC23	Cdc23p	0.201	Human
RPN2	Rpn2p	0.201
PUP2	Pup2p	0.200
RTS1	Rts1p	0.197
PRE4	Pre4p	0.195
RPN8	Rpn8p	0.194
MAD1	Mad1p	0.193
TIP41	Tip41p	0.193
GIP2	Gip2p	0.189	Yeast
PIG2	Pig2p	0.173	Yeast
NBL1	Nbl1p	0.170
KIP1	Kip1p	0.165
CDH1	Cdh1p	0.165
ZDS2	Zds2p	0.147
UBP6	Ubp6p	0.138
PPZ1	Ppz1p	0.133
MND2	Mnd2p	0.119
SLI15	Sli15p	0.111
CDC28	Cdc28p	0.110
APC2	Apc2p	0.106
BUB1	Bub1p	0.106
KSP1	Ksp1p	0.106
PRE7	Pre7p	0.105
CDC27	Cdc27p	0.104
IML3	Iml3p	0.100
GSY1	Gsy1p	0.098
DOC1	Doc1p	0.097
FMP48	Fmp48p	0.094
SIT4	Sit4p	0.092
HHO1	Hho1p	0.091
CIN8	Cin8p	0.088
BMH1	Bmh1p	0.084
PUP3	Pup3p	0.084
STI1	Sti1p	0.081
RPN13	Rpn13p	0.081
ZDS1	Zds1p	0.078
SEM1	Sem1p	0.076
APC4	Apc4p	0.073
VPS60	Vps60p	0.073
RPN14	Rpn14p	0.073
HAL5	Hal5p	0.069
RPN4	Rpn4p	0.067
SCL1	Scl1p	0.067
RPN5	Rpn5p	0.067
ASE1	Ase1p	0.065
APC11	Apc11p	0.064
IRC15	Irc15p	0.062
PSP1	Psp1p	0.061
CDC4	Cdc4p	0.060
RHO1	Rho1p	0.060
PRE5	Pre5p	0.059
PDS1	Pds1p	0.058
YAP1	Yap1p	0.058
HHF2	Hhf2p	0.057
ECO1	Eco1p	0.055
MAD3	Mad3p	0.054
HTA1	Hta1p	0.053
PUP1	Pup1p	0.053
YBP2	Ybp2p	0.053
SKM1	Skm1p	0.052
GLG1	Glg1p	0.052
NSL1	Nsl1p	0.051
HSF1	Hsf1p	0.051
MKS1	Mks1p	0.051
VPS41	Vps41p	0.051
YIR016W	hypothetical protein	0.051
GAC1	Gac1p	0.049
TAF7	Taf7p	0.047
YKL075C	hypothetical protein	0.046
FPK1	Fpk1p	0.046
MNN9	Mnn9p	0.045
YNL155W	hypothetical protein	0.045
UFD1	Ufd1p	0.045
PRE9	Pre9p	0.044
MSS4	Mss4p	0.044
SGT2	Sgt2p	0.044
TAF10	Taf10p	0.042
HSM3	Hsm3p	0.042
UMP1	Ump1p	0.042
GLN3	Gln3p	0.042
CTK3	Ctk3p	0.042
CDC37	Cdc37p	0.041
SUR1	Sur1p	0.041
ROX1	Rox1p	0.041
SOL1	Sol1p	0.040
SMC4	Smc4p	0.040
PRE8	Pre8p	0.040
CUR1	Cur1p	0.039
UBA4	Uba4p	0.039
RAD61	Rad61p	0.039
CHL4	Chl4p	0.039
SDS22	Sds22p	0.039
ATG20	Atg20p	0.039
KIC1	Kic1p	0.038
AHC2	Ahc2p	0.037
NFU1	Nfu1p	0.037
KIN3	Kin3p	0.037
TGL2	Tgl2p	0.037
PRP28	Prp28p	0.036
RMD5	Rmd5p	0.035
SLX8	Slx8p	0.035
STP2	Stp2p	0.034	Yeast
YDJ1	Ydj1p	0.034
CSE4	Cse4p	0.034
CTF19	Ctf19p	0.034
SPC24	Spc24p	0.033
MET4	Met4p	0.033
SWC4	Swc4p	0.032
UBC4	Ubc4p	0.032
NRG1	Nrg1p	0.032	Yeast
TAF11	Taf11p	0.031
RTS3	Rts3p	0.031
MMS21	Mms21p	0.031
YGL010W	hypothetical protein	0.031
BCK2	Bck2p	0.030
SPC110	Spc110p	0.030
STD1	Std1p	0.030
CDC48	Cdc48p	0.029	Human Rat
DAM1	Dam1p	0.029
SHP1	Shp1p	0.029
CTF3	Ctf3p	0.029
HHT1	Hht1p	0.029	Yeast
TRX3	Trx3p	0.029
ARF2	Arf2p	0.029
FYV10	Fyv10p	0.028
MTW1	Mtw1p	0.028
NCE103	Nce103p	0.028
FMP52	Fmp52p	0.027
PCL10	Pcl10p	0.027
UBR1	Ubr1p	0.027
SAP4	Sap4p	0.027
VIK1	Vik1p	0.027
RPN3	Rpn3p	0.027
STE4	Ste4p	0.027
SCC2	Scc2p	0.026
LEU2	Leu2p	0.026
UBC6	Ubc6p	0.026
YLR264C-A	hypothetical protein	0.026
RAD54	Rad54p	0.026
RAD30	Rad30p	0.025
CBF1	Cbf1p	0.025
YMR226C	hypothetical protein	0.025
PAR32	Par32p	0.025
MGA2	Mga2p	0.025
ARC15	Arc15p	0.025
YIL151C	hypothetical protein	0.024
SWM1	Swm1p	0.024
BIT61	Bit61p	0.024
PLC1	Plc1p	0.024
MEI5	Mei5p	0.024
MPT5	Mpt5p	0.024
NDD1	Ndd1p	0.024
PTI1	Pti1p	0.024
BFA1	Bfa1p	0.024
CIN1	Cin1p	0.023
RIM13	Rim13p	0.023
OTU1	Otu1p	0.023
SRD1	Srd1p	0.023
MER1	Mer1p	0.023
RIM4	Rim4p	0.023
YPL014W	hypothetical protein	0.022
HCH1	Hch1p	0.022
IME4	Ime4p	0.022
IRC23	Irc23p	0.022
THP3	Thp3p	0.022
MF(ALPHA)2	Mf(alpha)2p	0.022
CYC7	Cyc7p	0.022
SNF3	Snf3p	0.021
MND1	Mnd1p	0.021
UBP8	Ubp8p	0.021
FMT1	Fmt1p	0.021
STU1	Stu1p	0.021
PNG1	Png1p	0.021
TBS1	Tbs1p	0.021
NGG1	Ngg1p	0.021
SOK1	Sok1p	0.021
RDH54	Rdh54p	0.021
PSY4	Psy4p	0.021
SPC25	Spc25p	0.021
WSS1	Wss1p	0.021
YOL038C-A	hypothetical protein	0.020
HST3	Hst3p	0.020
YLR162W	hypothetical protein	0.020
PRE3	Pre3p	0.020
UBR2	Ubr2p	0.020
ARG8	Arg8p	0.020
CAF4	Caf4p	0.020
YGK3	Ygk3p	0.020
MCM21	Mcm21p	0.019
SHE10	She10p	0.019
SPS22	Sps22p	0.019
YAR068W	hypothetical protein	0.019
CUP1-1	Cup1-1p	0.019
BSC2	Bsc2p	0.019
MF(ALPHA)1	Mf(alpha)1p	0.019
TPI1	Tpi1p	0.018
RLM1	Rlm1p	0.018
ARE2	Are2p	0.018
KRE29	Kre29p	0.018
PRS2	Prs2p	0.018
CLB6	Clb6p	0.018
ERV2	Erv2p	0.018
CTI6	Cti6p	0.018
OAZ1	Oaz1p	0.018
TOD6	Tod6p	0.018
YLR042C	hypothetical protein	0.018
ROM1	Rom1p	0.017
MBF1	Mbf1p	0.017
YNR062C	hypothetical protein	0.017
ALT2	Alt2p	0.017
URA3	Ura3p	0.017
YKR011C	hypothetical protein	0.017
MRK1	Mrk1p	0.017
STB2	Stb2p	0.017
PPQ1	Ppq1p	0.017	Yeast
ZPS1	Zps1p	0.017
PHO80	Pho80p	0.017
AMD2	Amd2p	0.017
SPL2	Spl2p	0.017
DCC1	Dcc1p	0.016
PDR15	Pdr15p	0.016
HXT3	Hxt3p	0.016
TAF8	Taf8p	0.016
YIR035C	hypothetical protein	0.016
YLR407W	hypothetical protein	0.016
HUR1	Hur1p	0.016
TOS8	Tos8p	0.016
DRE2	Dre2p	0.016
GSY2	Gsy2p	0.016
YAR066W	hypothetical protein	0.016
CHL1	Chl1p	0.016
CHA1	Cha1p	0.016
BUL1	Bul1p	0.016
PUT4	Put4p	0.016
HDA2	Hda2p	0.016
YKR075C	hypothetical protein	0.016
AUA1	Aua1p	0.016
CPD1	Cpd1p	0.016
RAD53	Rad53p	0.016
YNL144C	hypothetical protein	0.016
ADH2	Adh2p	0.016
NOP10	Nop10p	0.015
UPS3	Ups3p	0.015
YNL234W	hypothetical protein	0.015
ICS2	Ics2p	0.015
CAR1	Car1p	0.015
CSM1	Csm1p	0.015
UBA3	Uba3p	0.015
BNA4	Bna4p	0.015
QNS1	Qns1p	0.015
TAF3	Taf3p	0.015
PMA2	Pma2p	0.015
STS1	Sts1p	0.015
PCT1	Pct1p	0.015
NSE1	Nse1p	0.015
KTI11	Kti11p	0.015
ECT1	Ect1p	0.015
LSM12	Lsm12p	0.015
ATP6	Atp6p	0.015
YBL036C	hypothetical protein	0.015
HPF1	Hpf1p	0.015
UIP5	Uip5p	0.015
HRR25	Hrr25p	0.015	Mouse Fly
SGT1	Sgt1p	0.015
AAD6	Aad6p	0.015
ARP10	Arp10p	0.015
SET4	Set4p	0.015
YBR013C	hypothetical protein	0.015
GLG2	Glg2p	0.015
MSG5	Msg5p	0.014
TYE7	Tye7p	0.014
ADE8	Ade8p	0.014
YNL295W	hypothetical protein	0.014
ZEO1	Zeo1p	0.014
GYL1	Gyl1p	0.014
DTR1	Dtr1p	0.014
YER137C	hypothetical protein	0.014
HMS1	Hms1p	0.014
OPT2	Opt2p	0.014
NVJ1	Nvj1p	0.014
ESP1	Esp1p	0.014
SBH2	Sbh2p	0.014
RAD27	Rad27p	0.014
HUL5	Hul5p	0.014
YOL013W-A	hypothetical protein	0.014
BIO2	Bio2p	0.014
SOL3	Sol3p	0.014
YOR385W	hypothetical protein	0.014
IST1	Ist1p	0.014
DUG3	Dug3p	0.014
PPR1	Ppr1p	0.014
DST1	Dst1p	0.014
YDL085C-A	hypothetical protein	0.014
RRD2	Rrd2p	0.014
YNL024C	hypothetical protein	0.014
FOL2	Fol2p	0.014
AQY2	Aqy2p	0.014
APC5	Apc5p	0.014
SAR1	Sar1p	0.014
DIF1	Dif1p	0.013
BUR6	Bur6p	0.013
YPR157W	hypothetical protein	0.013
YBL044W	hypothetical protein	0.013
FAU1	Fau1p	0.013
YLR040C	hypothetical protein	0.013
YML003W	hypothetical protein	0.013
AGE1	Age1p	0.013
PTR2	Ptr2p	0.013
AVL9	Avl9p	0.013
HO	Hop	0.013
AAD15	Aad15p	0.013
NRG2	Nrg2p	0.013
MOB1	Mob1p	0.013
NST1	Nst1p	0.013
YLR281C	hypothetical protein	0.013
YMR244C-A	hypothetical protein	0.013
YBL029W	hypothetical protein	0.013
REG1	Reg1p	0.013
CBF2	Cbf2p	0.013
YDL012C	hypothetical protein	0.013
WWM1	Wwm1p	0.013
BSD2	Bsd2p	0.013
CRP1	Crp1p	0.013
YMR122W-A	hypothetical protein	0.013
ENO1	Eno1p	0.013
RAD52	Rad52p	0.013
GNA1	Gna1p	0.012
PPX1	Ppx1p	0.012
BRN1	Brn1p	0.012
TIM22	Tim22p	0.012
HIT1	Hit1p	0.012
AHP1	Ahp1p	0.012
YLR445W	hypothetical protein	0.012
YNL058C	hypothetical protein	0.012
TIP1	Tip1p	0.012
UTR4	Utr4p	0.012
ADD66	Add66p	0.012
YAL037C-A	hypothetical protein	0.012
YJL160C	hypothetical protein	0.012
CAB3	Cab3p	0.012
YMR317W	hypothetical protein	0.012
RRT5	Rrt5p	0.012
BET4	Bet4p	0.012
CCW12	Ccw12p	0.012
SGF73	Sgf73p	0.012
HOR2	Hor2p	0.012
NSE5	Nse5p	0.012
YML053C	hypothetical protein	0.012
YPR096C	hypothetical protein	0.012
YLL053C	hypothetical protein	0.012
CAB4	Cab4p	0.012
FCY1	Fcy1p	0.012
CMD1	Cmd1p	0.012
YIL001W	hypothetical protein	0.012
MCM22	Mcm22p	0.012
ACE2	Ace2p	0.012
YOR302W	hypothetical protein	0.012
SCS22	Scs22p	0.012
YLR225C	hypothetical protein	0.012
NTO1	Nto1p	0.012
ACA1	Aca1p	0.012
YCK3	Yck3p	0.012
ULP1	Ulp1p	0.012	Yeast
PFS1	Pfs1p	0.012
YCH1	Ych1p	0.012
SPS4	Sps4p	0.012
YJR120W	hypothetical protein	0.012
YIR042C	hypothetical protein	0.012
RNP1	Rnp1p	0.012
SIZ1	Siz1p	0.012
PHM6	Phm6p	0.012
CTF8	Ctf8p	0.012
TID3	Tid3p	0.011
YOR012W	hypothetical protein	0.011
TCP1	Tcp1p	0.011
TIR3	Tir3p	0.011
SPO19	Spo19p	0.011
CSL4	Csl4p	0.011
YNL067W-B	hypothetical protein	0.011
SRT1	Srt1p	0.011
ISU2	Isu2p	0.011
PKC1	Pkc1p	0.011	Mouse
ICY1	Icy1p	0.011
YGL006W-A	hypothetical protein	0.011
TAH1	Tah1p	0.011
SMC5	Smc5p	0.011	Human
YPR015C	hypothetical protein	0.011
HOT13	Hot13p	0.011
UFD2	Ufd2p	0.011
RHO5	Rho5p	0.011
APT2	Apt2p	0.011
YNL033W	hypothetical protein	0.011
REE1	Ree1p	0.011
GDS1	Gds1p	0.011
ARR2	Arr2p	0.011
CIN2	Cin2p	0.011
YER010C	hypothetical protein	0.011
HLJ1	Hlj1p	0.011
RIB7	Rib7p	0.011
COS12	Cos12p	0.011
CAK1	Cak1p	0.011
CTR86	Ctr86p	0.011
SAC6	Sac6p	0.011
PPG1	Ppg1p	0.011	Yeast
PTR3	Ptr3p	0.011
MFA2	Mfa2p	0.011
ARO10	Aro10p	0.011
RXT2	Rxt2p	0.011
SIT1	Sit1p	0.011
RAD51	Rad51p	0.011
SGE1	Sge1p	0.011
DIC1	Dic1p	0.011
YPL216W	hypothetical protein	0.011
YOR262W	hypothetical protein	0.011
PGA2	Pga2p	0.011
IAH1	Iah1p	0.011
PKH2	Pkh2p	0.011
SRX1	Srx1p	0.011
APC1	Apc1p	0.011
PCL5	Pcl5p	0.011
YDL186W	hypothetical protein	0.011
MMF1	Mmf1p	0.011
LCL1	Lcl1p	0.011
GLN1	Gln1p	0.011
YAK1	Yak1p	0.011
MET12	Met12p	0.011
MDJ2	Mdj2p	0.011
SNA2	Sna2p	0.011
STE18	Ste18p	0.011
YPR027C	hypothetical protein	0.011
IML1	Iml1p	0.011
SSP1	Ssp1p	0.011
YJU2	Yju2p	0.011
SWC7	Swc7p	0.011
CLB1	Clb1p	0.011
YBR296C-A	hypothetical protein	0.011
YBR138C	hypothetical protein	0.011
YGR035C	hypothetical protein	0.011
YDR034C-A	hypothetical protein	0.011
APA2	Apa2p	0.011
PMP2	Pmp2p	0.010
YNL162W-A	hypothetical protein	0.010
TRI1	Tri1p	0.010
FRA1	Fra1p	0.010
VBA5	Vba5p	0.010
HSK3	Hsk3p	0.010
OST4	Ost4p	0.010
YJL055W	hypothetical protein	0.010
PYC2	Pyc2p	0.010
YJR115W	hypothetical protein	0.010
COS111	Cos111p	0.010
TSC3	Tsc3p	0.010
APC9	Apc9p	0.010
YAL018C	hypothetical protein	0.010
YDR179W-A	hypothetical protein	0.010
YHR131C	hypothetical protein	0.010
GPD2	Gpd2p	0.010
YNR014W	hypothetical protein	0.010
RCO1	Rco1p	0.010
BAP2	Bap2p	0.010
SIS2	Sis2p	0.010
HSV2	Hsv2p	0.010
RSC4	Rsc4p	0.010
YLR012C	hypothetical protein	0.010
YAL064W	hypothetical protein	0.010
YKL069W	hypothetical protein	0.010
FCY22	Fcy22p	0.010
YNL034W	hypothetical protein	0.010
SCM4	Scm4p	0.010
GID8	Gid8p	0.010
TEF1	Tef1p	0.010
HTA2	Hta2p	0.010
YAR029W	hypothetical protein	0.010
YKR041W	hypothetical protein	0.010
BDS1	Bds1p	0.010
BSC1	Bsc1p	0.010
PRM4	Prm4p	0.010
SPS100	Sps100p	0.010
DAL82	Dal82p	0.010
AMA1	Ama1p	0.010	Yeast