IMP

Process View

Saccharomyces cerevisiae

24 genes annotated in yeast

negative regulation of proteasomal ubiquitin dependent protein catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of proteasomal ubiquitin dependent protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of proteasomal ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
MAD2	Mad2p	0.944
CDC20	Cdc20p	0.925
PPH21	Pph21p	0.923
PPH22	Pph22p	0.757
CDC55	Cdc55p	0.702
PIG2	Pig2p	0.496	Yeast
SLK19	Slk19p	0.436
RTS1	Rts1p	0.323
CHL4	Chl4p	0.321
CTF13	Ctf13p	0.314
MAD3	Mad3p	0.288
IML3	Iml3p	0.282
KIP1	Kip1p	0.244
YPI1	Ypi1p	0.213
MAD1	Mad1p	0.208
SDS22	Sds22p	0.172
SLI15	Sli15p	0.171
GIP2	Gip2p	0.162	Yeast
PPZ1	Ppz1p	0.145
BUB3	Bub3p	0.139	Worm Fly
NSL1	Nsl1p	0.131
BUB1	Bub1p	0.115
ASE1	Ase1p	0.106
DSK2	Dsk2p	0.104
CTF3	Ctf3p	0.102
MTW1	Mtw1p	0.102
FMP48	Fmp48p	0.101
HTA1	Hta1p	0.095
SPC24	Spc24p	0.092
TIP41	Tip41p	0.072
HHT2	Hht2p	0.070
STE4	Ste4p	0.069
HHT1	Hht1p	0.065	Yeast
NBL1	Nbl1p	0.061
CDC37	Cdc37p	0.060
HST3	Hst3p	0.060
YIL151C	hypothetical protein	0.056
GLC7	Glc7p	0.053
MLC1	Mlc1p	0.052
RPT6	Rpt6p	0.051
TAF10	Taf10p	0.051
RAD54	Rad54p	0.051
HIT1	Hit1p	0.051
PTI1	Pti1p	0.049
YBP2	Ybp2p	0.049
NDD1	Ndd1p	0.049
RPT1	Rpt1p	0.048
CSE4	Cse4p	0.047
NTO1	Nto1p	0.045
HHF2	Hhf2p	0.042
SMC4	Smc4p	0.042
BCK2	Bck2p	0.042
TGL2	Tgl2p	0.042
TID3	Tid3p	0.039
TRA1	Tra1p	0.038
TPI1	Tpi1p	0.038
YNL144C	hypothetical protein	0.036
PRS2	Prs2p	0.036
SAP4	Sap4p	0.035
SPC110	Spc110p	0.035
RRN3	Rrn3p	0.034
SRD1	Srd1p	0.034
GAC1	Gac1p	0.033
YLR264C-A	hypothetical protein	0.033
CTF19	Ctf19p	0.033
YKL075C	hypothetical protein	0.032
CRP1	Crp1p	0.032
BDF2	Bdf2p	0.031
PCL10	Pcl10p	0.031
GLG1	Glg1p	0.031
YOL038C-A	hypothetical protein	0.031
YLR162W	hypothetical protein	0.030
LEU2	Leu2p	0.030
YNR014W	hypothetical protein	0.029
DSN1	Dsn1p	0.028
YIR035C	hypothetical protein	0.028
UFD2	Ufd2p	0.027
MER1	Mer1p	0.027
STD1	Std1p	0.027
CBF2	Cbf2p	0.027
CIN1	Cin1p	0.027
YAR068W	hypothetical protein	0.027
YML053C	hypothetical protein	0.027
CDC28	Cdc28p	0.026
YNR062C	hypothetical protein	0.026
SUR1	Sur1p	0.026
IPL1	Ipl1p	0.025
OKP1	Okp1p	0.025
YGL010W	hypothetical protein	0.025
URA3	Ura3p	0.025
IRC8	Irc8p	0.025
STU1	Stu1p	0.025
SKM1	Skm1p	0.024
CUP1-1	Cup1-1p	0.024
DAM1	Dam1p	0.024
ZDS1	Zds1p	0.024
SWR1	Swr1p	0.024
FYV10	Fyv10p	0.023
MEC1	Mec1p	0.023
YDL012C	hypothetical protein	0.023
ZPS1	Zps1p	0.023
AQR1	Aqr1p	0.023
ARG8	Arg8p	0.023
ECO1	Eco1p	0.023
MCM21	Mcm21p	0.023
VHS2	Vhs2p	0.023
HAL1	Hal1p	0.022
PPQ1	Ppq1p	0.022	Yeast
SPC105	Spc105p	0.022
RAD61	Rad61p	0.022
YLR042C	hypothetical protein	0.022
ADH2	Adh2p	0.022
KEL2	Kel2p	0.022
SPO12	Spo12p	0.022
BFA1	Bfa1p	0.022
RPT3	Rpt3p	0.022
SWC7	Swc7p	0.022
HXT3	Hxt3p	0.022
ARP10	Arp10p	0.021
PRE10	Pre10p	0.021
RFC2	Rfc2p	0.021
YKR075C	hypothetical protein	0.021
SET4	Set4p	0.021
TAF13	Taf13p	0.021
SPL2	Spl2p	0.020
FAU1	Fau1p	0.020
STI1	Sti1p	0.020
CSL4	Csl4p	0.020
YPR157W	hypothetical protein	0.020
ATP6	Atp6p	0.020
SWD3	Swd3p	0.020
HPF1	Hpf1p	0.020
COS111	Cos111p	0.020
NCE103	Nce103p	0.020
PRE1	Pre1p	0.020
MRK1	Mrk1p	0.019
SWI1	Swi1p	0.019
YBR013C	hypothetical protein	0.019
TSC3	Tsc3p	0.019
CPD1	Cpd1p	0.019
SGE1	Sge1p	0.019
YAR066W	hypothetical protein	0.019
AUA1	Aua1p	0.019
BIO2	Bio2p	0.019
CHA1	Cha1p	0.019
PCT1	Pct1p	0.019
CDC16	Cdc16p	0.019
PRP28	Prp28p	0.019
STB2	Stb2p	0.018
BNA4	Bna4p	0.018
OTU1	Otu1p	0.018
PTR2	Ptr2p	0.018
PDR15	Pdr15p	0.018
THG1	Thg1p	0.018
PAM1	Pam1p	0.018
RPT4	Rpt4p	0.018
IML1	Iml1p	0.018
SMC5	Smc5p	0.018
RMD5	Rmd5p	0.018
POP6	Pop6p	0.018
SFI1	Sfi1p	0.018
UPS3	Ups3p	0.017
MOB1	Mob1p	0.017
PUP2	Pup2p	0.017
ICS2	Ics2p	0.017
YOL013W-A	hypothetical protein	0.017
PSP1	Psp1p	0.017
CAK1	Cak1p	0.017
RFA1	Rfa1p	0.017
YLR281C	hypothetical protein	0.016
SNF11	Snf11p	0.016
YGR079W	hypothetical protein	0.016
MF(ALPHA)2	Mf(alpha)2p	0.016
AAD6	Aad6p	0.016
SPS4	Sps4p	0.016
BSC1	Bsc1p	0.016
TYE7	Tye7p	0.016
CLB1	Clb1p	0.016
NGG1	Ngg1p	0.016
PUF2	Puf2p	0.016
MIF2	Mif2p	0.016
REH1	Reh1p	0.016
YEA6	Yea6p	0.016
YNL155W	hypothetical protein	0.016
ZIP1	Zip1p	0.016
AAD15	Aad15p	0.016
DCC1	Dcc1p	0.016
PRE2	Pre2p	0.016
SPC25	Spc25p	0.015
YLR040C	hypothetical protein	0.015
ALT2	Alt2p	0.015
FMT1	Fmt1p	0.015
PKC1	Pkc1p	0.015
ARE2	Are2p	0.015
SAP185	Sap185p	0.015
YGK3	Ygk3p	0.015
ARR2	Arr2p	0.015
YBL029W	hypothetical protein	0.015
YJL181W	hypothetical protein	0.015
YOR262W	hypothetical protein	0.015
YOL014W	hypothetical protein	0.015
NRG2	Nrg2p	0.015
YML003W	hypothetical protein	0.015
VHS3	Vhs3p	0.015
TPM2	Tpm2p	0.014
PUP3	Pup3p	0.014
DIC1	Dic1p	0.014
YPR096C	hypothetical protein	0.014
TOR2	Tor2p	0.014
YAL037C-A	hypothetical protein	0.014
NUP49	Nup49p	0.014
DIF1	Dif1p	0.014
FRA2	Fra2p	0.014
LIF1	Lif1p	0.014
HHO1	Hho1p	0.014
CDC4	Cdc4p	0.014
RHO1	Rho1p	0.014
YAL064W	hypothetical protein	0.014
OPT2	Opt2p	0.014
VBA5	Vba5p	0.014
RTT105	Rtt105p	0.014
PMA2	Pma2p	0.014
NNF1	Nnf1p	0.014
CAR1	Car1p	0.014
YPL216W	hypothetical protein	0.014
YGL006W-A	hypothetical protein	0.014
YDR306C	hypothetical protein	0.014
RNP1	Rnp1p	0.014
MMP1	Mmp1p	0.014
IZH4	Izh4p	0.014
YNL234W	hypothetical protein	0.013
GIP3	Gip3p	0.013
HMRA1	Hmra1p	0.013
YMR317W	hypothetical protein	0.013
PHM6	Phm6p	0.013
YIR042C	hypothetical protein	0.013
BIT61	Bit61p	0.013
ISU2	Isu2p	0.013
RAD23	Rad23p	0.013
YMR122W-A	hypothetical protein	0.013
RTS2	Rts2p	0.013
YJL218W	hypothetical protein	0.013
LCL1	Lcl1p	0.013
NEO1	Neo1p	0.013
MCM22	Mcm22p	0.013
YCR102C	hypothetical protein	0.013
YNL033W	hypothetical protein	0.013
BDS1	Bds1p	0.013
SRO77	Sro77p	0.013
MET31	Met31p	0.013
SFT1	Sft1p	0.013
MPH1	Mph1p	0.013
YNL067W-B	hypothetical protein	0.013
YDR034C-A	hypothetical protein	0.013
MET8	Met8p	0.013
MHT1	Mht1p	0.013
WSS1	Wss1p	0.013
CCT2	Cct2p	0.013
SYN8	Syn8p	0.013
ICY1	Icy1p	0.012
TPD3	Tpd3p	0.012
TIR3	Tir3p	0.012
SCM4	Scm4p	0.012
REE1	Ree1p	0.012
KIN3	Kin3p	0.012
WSC4	Wsc4p	0.012
DUR1,2	Dur1,2p	0.012
YER186C	hypothetical protein	0.012
SRX1	Srx1p	0.012
PDS1	Pds1p	0.012
RRN5	Rrn5p	0.012
RMD6	Rmd6p	0.012
TIP1	Tip1p	0.012
YLR225C	hypothetical protein	0.012
YOR059C	hypothetical protein	0.012
MND1	Mnd1p	0.012
ERV2	Erv2p	0.012
YKR041W	hypothetical protein	0.012
GNA1	Gna1p	0.012
TIM22	Tim22p	0.012
YPL168W	hypothetical protein	0.012
YDR222W	hypothetical protein	0.012
NUF2	Nuf2p	0.012
HOR2	Hor2p	0.012
YCR050C	hypothetical protein	0.012
ARO10	Aro10p	0.012
MTH1	Mth1p	0.012
PRE6	Pre6p	0.012
RIB7	Rib7p	0.012
TAM41	Tam41p	0.012
YAR029W	hypothetical protein	0.012
YBR296C-A	hypothetical protein	0.012
ENA5	Ena5p	0.012
AQY2	Aqy2p	0.012
YNL018C	hypothetical protein	0.012
YPL067C	hypothetical protein	0.012
GIC1	Gic1p	0.012
YGR035C	hypothetical protein	0.012
MFA2	Mfa2p	0.012
PRM4	Prm4p	0.012
COS12	Cos12p	0.012
YOR387C	hypothetical protein	0.012
OAF1	Oaf1p	0.012
RRT5	Rrt5p	0.012
SSP1	Ssp1p	0.012
RRN7	Rrn7p	0.012
MF(ALPHA)1	Mf(alpha)1p	0.011
IRC15	Irc15p	0.011
YIR014W	hypothetical protein	0.011
YPR027C	hypothetical protein	0.011
YDR524W-C	hypothetical protein	0.011
PZF1	Pzf1p	0.011
SCC2	Scc2p	0.011
TAD2	Tad2p	0.011
YJR120W	hypothetical protein	0.011
YLR412C-A	hypothetical protein	0.011
RPT2	Rpt2p	0.011
IME4	Ime4p	0.011
FIN1	Fin1p	0.011
ADD66	Add66p	0.011
YJL160C	hypothetical protein	0.011
TRI1	Tri1p	0.011
YJL147C	hypothetical protein	0.011
CDC27	Cdc27p	0.011
YCH1	Ych1p	0.011
MDE1	Mde1p	0.011
THP3	Thp3p	0.011
HAL5	Hal5p	0.011
PCD1	Pcd1p	0.011
YGR017W	hypothetical protein	0.011
CTS1	Cts1p	0.011
KNH1	Knh1p	0.011
PHO11	Pho11p	0.011
AIF1	Aif1p	0.011
DOG1	Dog1p	0.011
TIM12	Tim12p	0.011
YLR445W	hypothetical protein	0.011
UTR4	Utr4p	0.011
YLR460C	hypothetical protein	0.011
HO	Hop	0.011
GYL1	Gyl1p	0.011
DSS4	Dss4p	0.011
RPN9	Rpn9p	0.011
RAM2	Ram2p	0.011
PDC6	Pdc6p	0.011
YDL186W	hypothetical protein	0.011
POM34	Pom34p	0.011
YCL001W-B	hypothetical protein	0.011
YLR278C	hypothetical protein	0.011
YDR186C	hypothetical protein	0.011
QNS1	Qns1p	0.011
SAG1	Sag1p	0.011
ISF1	Isf1p	0.011
YNL162W-A	hypothetical protein	0.011
YML100W-A	hypothetical protein	0.011
CFD1	Cfd1p	0.011
PUP1	Pup1p	0.010
MMS21	Mms21p	0.010
RPI1	Rpi1p	0.010
FCY22	Fcy22p	0.010
UFD1	Ufd1p	0.010
YPR159C-A	hypothetical protein	0.010
IMA5	Ima5p	0.010
YHR162W	hypothetical protein	0.010
ENO1	Eno1p	0.010
YGR205W	hypothetical protein	0.010
TAF8	Taf8p	0.010
FRE5	Fre5p	0.010
DAK2	Dak2p	0.010
BIO5	Bio5p	0.010
REG2	Reg2p	0.010
EAF1	Eaf1p	0.010
BET5	Bet5p	0.010
YPR117W	hypothetical protein	0.010
SRT1	Srt1p	0.010
CDC48	Cdc48p	0.010
SEO1	Seo1p	0.010
YDR210W	hypothetical protein	0.010
YNL058C	hypothetical protein	0.010
TIS11	Tis11p	0.010
RCO1	Rco1p	0.010
YHR033W	hypothetical protein	0.010
YBP1	Ybp1p	0.010
YOR012W	hypothetical protein	0.010
MIG2	Mig2p	0.010
YKL070W	hypothetical protein	0.010