IMP

Process View

Saccharomyces cerevisiae

28 genes annotated in yeast

metaphase anaphase transition of mitotic cell cycle

The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "metaphase anaphase transition of mitotic cell cycle"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "metaphase anaphase transition of mitotic cell cycle" (in gray)

Name	Description	Probability	Func Analog Organism
CDC16	Cdc16p	0.999	Fly
CDC27	Cdc27p	0.994	Human Worm
CDC23	Cdc23p	0.993	Human
MAD2	Mad2p	0.987
CDC20	Cdc20p	0.985
DOC1	Doc1p	0.973
MPS1	Mps1p	0.936
SLK19	Slk19p	0.923
MTW1	Mtw1p	0.914
CDC26	Cdc26p	0.867
PPH22	Pph22p	0.857
SPC105	Spc105p	0.857
GLC7	Glc7p	0.853
APC4	Apc4p	0.847
APC2	Apc2p	0.845
TID3	Tid3p	0.827
NSL1	Nsl1p	0.810
SWM1	Swm1p	0.806
CSE4	Cse4p	0.770
DSN1	Dsn1p	0.757
PPH21	Pph21p	0.754
SLI15	Sli15p	0.739
MND2	Mnd2p	0.733
BUB1	Bub1p	0.706
CDC55	Cdc55p	0.669	Fly
PPZ1	Ppz1p	0.615
APC1	Apc1p	0.571
PIG2	Pig2p	0.569	Yeast
APC5	Apc5p	0.563
MIF2	Mif2p	0.525
SMC4	Smc4p	0.522
MCM21	Mcm21p	0.504
BUB3	Bub3p	0.501	Worm Fly
CTF3	Ctf3p	0.440
GIP2	Gip2p	0.376	Yeast
RPT1	Rpt1p	0.362
SPC24	Spc24p	0.356
HHF2	Hhf2p	0.348
RTS1	Rts1p	0.334
YBP2	Ybp2p	0.332
PDS1	Pds1p	0.327
RPT4	Rpt4p	0.323
CHL4	Chl4p	0.308
KIP1	Kip1p	0.294
PRE10	Pre10p	0.273
RPT3	Rpt3p	0.256
MAD3	Mad3p	0.254
PRE6	Pre6p	0.249
AME1	Ame1p	0.230
OKP1	Okp1p	0.216
IML3	Iml3p	0.216
PRE2	Pre2p	0.203
APC11	Apc11p	0.187
NUF2	Nuf2p	0.185
IPL1	Ipl1p	0.178
TIP41	Tip41p	0.178
PUP2	Pup2p	0.170
APC9	Apc9p	0.164
CTF19	Ctf19p	0.145
FMP48	Fmp48p	0.141
PUP1	Pup1p	0.135
BIR1	Bir1p	0.133
RPN7	Rpn7p	0.132
PRE1	Pre1p	0.119
CDH1	Cdh1p	0.119
MCM22	Mcm22p	0.115
PUP3	Pup3p	0.114
PSH1	Psh1p	0.113
RPN2	Rpn2p	0.112
MAD1	Mad1p	0.112
CBF2	Cbf2p	0.110
STU1	Stu1p	0.106
NNF1	Nnf1p	0.105
RPN11	Rpn11p	0.101
RPN6	Rpn6p	0.096
SMC6	Smc6p	0.096
MMS21	Mms21p	0.094
RPN9	Rpn9p	0.094
CIN8	Cin8p	0.093
SPC25	Spc25p	0.089
SMC2	Smc2p	0.087
ECO1	Eco1p	0.087
YPI1	Ypi1p	0.086
ZDS2	Zds2p	0.077
PRE4	Pre4p	0.077
PRE7	Pre7p	0.073
RPN12	Rpn12p	0.063
SDS22	Sds22p	0.062
PSY4	Psy4p	0.060
NTO1	Nto1p	0.055
VIK1	Vik1p	0.053
YKL075C	hypothetical protein	0.053
RPN1	Rpn1p	0.052
KIC1	Kic1p	0.050
RPN10	Rpn10p	0.049
BRN1	Brn1p	0.047
BFA1	Bfa1p	0.047
PRP28	Prp28p	0.046
IRC15	Irc15p	0.046
ESP1	Esp1p	0.045
FIN1	Fin1p	0.042
GSY2	Gsy2p	0.039
CBF1	Cbf1p	0.038
DCC1	Dcc1p	0.038
NBL1	Nbl1p	0.038
PTI1	Pti1p	0.036
RPN8	Rpn8p	0.035
GSY1	Gsy1p	0.034
PDS5	Pds5p	0.033
SCL1	Scl1p	0.032
ECM29	Ecm29p	0.032
PRE5	Pre5p	0.031
SUR1	Sur1p	0.031
SPO12	Spo12p	0.031
RPN5	Rpn5p	0.030
RDH54	Rdh54p	0.029
GAC1	Gac1p	0.029
CIN1	Cin1p	0.029
PKC1	Pkc1p	0.029
ZDS1	Zds1p	0.028
RAD53	Rad53p	0.028
VHS2	Vhs2p	0.028
CAB3	Cab3p	0.027
SCM3	Scm3p	0.027
RPN14	Rpn14p	0.027
SRD1	Srd1p	0.026
BIM1	Bim1p	0.026
AGE1	Age1p	0.026
MAM1	Mam1p	0.025
PRE8	Pre8p	0.025
RPT2	Rpt2p	0.025
YNL155W	hypothetical protein	0.025
KAR3	Kar3p	0.025
HUL5	Hul5p	0.025
LEU2	Leu2p	0.025
YNL144C	hypothetical protein	0.025
CUP1-1	Cup1-1p	0.024
YLR162W	hypothetical protein	0.024
CRP1	Crp1p	0.024
YLR264C-A	hypothetical protein	0.024
YOL038C-A	hypothetical protein	0.024
ARG8	Arg8p	0.024
SOL1	Sol1p	0.024
RAD61	Rad61p	0.023
DAM1	Dam1p	0.023
RTS2	Rts2p	0.023
UFD1	Ufd1p	0.023
SMC5	Smc5p	0.023	Human
SMC3	Smc3p	0.022
MER1	Mer1p	0.022
YML053C	hypothetical protein	0.022
SAP185	Sap185p	0.021
CDC28	Cdc28p	0.021
ARP10	Arp10p	0.021
SKM1	Skm1p	0.021
IML1	Iml1p	0.020
SPC97	Spc97p	0.020
SPT2	Spt2p	0.020
SFI1	Sfi1p	0.020
SWI1	Swi1p	0.020
NDD1	Ndd1p	0.020
MRK1	Mrk1p	0.020
PCT1	Pct1p	0.020
FMT1	Fmt1p	0.020
GLG1	Glg1p	0.019
PDR15	Pdr15p	0.019
SLD3	Sld3p	0.019
NEO1	Neo1p	0.019
CFD1	Cfd1p	0.019
MYO1	Myo1p	0.019
SPC110	Spc110p	0.019
HPF1	Hpf1p	0.018
YAR068W	hypothetical protein	0.018
TRA1	Tra1p	0.018
SCC2	Scc2p	0.018
YLR042C	hypothetical protein	0.017
KRE29	Kre29p	0.017
UPS3	Ups3p	0.017
YBR013C	hypothetical protein	0.017
MND1	Mnd1p	0.017
YIL151C	hypothetical protein	0.017
SPL2	Spl2p	0.017
URA3	Ura3p	0.017
ZPS1	Zps1p	0.017
CPD1	Cpd1p	0.017
RAD30	Rad30p	0.017
TAF7	Taf7p	0.017
YKR075C	hypothetical protein	0.017
YIL001W	hypothetical protein	0.017
YPR157W	hypothetical protein	0.017
ATP6	Atp6p	0.017
YNR014W	hypothetical protein	0.017
SET4	Set4p	0.016
YNL234W	hypothetical protein	0.016
CLB1	Clb1p	0.016
ASE1	Ase1p	0.016
ADH2	Adh2p	0.016
OPT2	Opt2p	0.016
RFA1	Rfa1p	0.016
AUA1	Aua1p	0.016
PRE3	Pre3p	0.016
STB2	Stb2p	0.016
TPI1	Tpi1p	0.015
CNN1	Cnn1p	0.015
RPT5	Rpt5p	0.015
YLR407W	hypothetical protein	0.015
HXT3	Hxt3p	0.015
YBR296C-A	hypothetical protein	0.015
SSP1	Ssp1p	0.015
HO	Hop	0.015
SWC4	Swc4p	0.015
MCM16	Mcm16p	0.015
AQR1	Aqr1p	0.015
RMD5	Rmd5p	0.015
NUP49	Nup49p	0.014
NKP2	Nkp2p	0.014
CHA1	Cha1p	0.014
ICS2	Ics2p	0.014
BSC1	Bsc1p	0.014
ARO10	Aro10p	0.014
ISF1	Isf1p	0.014
ALT2	Alt2p	0.014
KEL1	Kel1p	0.014
CTF13	Ctf13p	0.014
SPO22	Spo22p	0.014
MPS2	Mps2p	0.014
MF(ALPHA)2	Mf(alpha)2p	0.014
WSS1	Wss1p	0.014
CTR86	Ctr86p	0.014
NRG2	Nrg2p	0.014
YPL014W	hypothetical protein	0.014
YML003W	hypothetical protein	0.014
YDR179W-A	hypothetical protein	0.014
MGS1	Mgs1p	0.013
HYM1	Hym1p	0.013
BCK2	Bck2p	0.013
YGL010W	hypothetical protein	0.013
SPS4	Sps4p	0.013
RRN5	Rrn5p	0.013
IZH4	Izh4p	0.013
ARE2	Are2p	0.013
PTR2	Ptr2p	0.013
TYE7	Tye7p	0.013
YOL013W-A	hypothetical protein	0.013
GIP3	Gip3p	0.013
YIR035C	hypothetical protein	0.013
YAL037C-A	hypothetical protein	0.013
CAB4	Cab4p	0.013
PUF2	Puf2p	0.013
YAR066W	hypothetical protein	0.013
IKI1	Iki1p	0.013
YPL067C	hypothetical protein	0.013
CDC4	Cdc4p	0.013
AAD6	Aad6p	0.013
SIS2	Sis2p	0.013
DIF1	Dif1p	0.013
IPT1	Ipt1p	0.013
MDJ2	Mdj2p	0.013
YLR040C	hypothetical protein	0.013
SWC7	Swc7p	0.012
PRS2	Prs2p	0.012
BDF2	Bdf2p	0.012
BIT61	Bit61p	0.012
CAF130	Caf130p	0.012
RAD59	Rad59p	0.012
YGK3	Ygk3p	0.012
YNL190W	hypothetical protein	0.012
VBA5	Vba5p	0.012
YJL218W	hypothetical protein	0.012
RRT5	Rrt5p	0.012
SRT1	Srt1p	0.012
DIC1	Dic1p	0.012
CAR1	Car1p	0.012
SGE1	Sge1p	0.012
MPT5	Mpt5p	0.012
HOR2	Hor2p	0.012
BIO2	Bio2p	0.012
OAF1	Oaf1p	0.012
PLC1	Plc1p	0.012
YBL029W	hypothetical protein	0.012
ARR2	Arr2p	0.012
YAL064W	hypothetical protein	0.012
RHO1	Rho1p	0.012
HAL1	Hal1p	0.012
YJL160C	hypothetical protein	0.012
FAP1	Fap1p	0.012
YGL006W-A	hypothetical protein	0.012
YNR062C	hypothetical protein	0.011
YMR317W	hypothetical protein	0.011
YEA6	Yea6p	0.011
ENA5	Ena5p	0.011
PBP2	Pbp2p	0.011
TFA1	Tfa1p	0.011
YDR506C	hypothetical protein	0.011
CDC7	Cdc7p	0.011
AAD15	Aad15p	0.011
TIM22	Tim22p	0.011
BNA4	Bna4p	0.011
LCL1	Lcl1p	0.011
YNL033W	hypothetical protein	0.011
VHS3	Vhs3p	0.011
MFA2	Mfa2p	0.011
RIM4	Rim4p	0.011
PAC2	Pac2p	0.011
CUP1-2	Cup1-2p	0.011
YBR138C	hypothetical protein	0.011
AMA1	Ama1p	0.011	Yeast
YIR042C	hypothetical protein	0.011
YDL186W	hypothetical protein	0.011
HAC1	Hac1p	0.011
TIP1	Tip1p	0.011
CHL1	Chl1p	0.011
TGL2	Tgl2p	0.011
DUG3	Dug3p	0.011
PCL10	Pcl10p	0.011
RNP1	Rnp1p	0.011
HLJ1	Hlj1p	0.011
PRM4	Prm4p	0.011
YPR117W	hypothetical protein	0.011
YLR108C	hypothetical protein	0.011
FYV10	Fyv10p	0.011
RTT105	Rtt105p	0.011
YPL277C	hypothetical protein	0.011
SCM4	Scm4p	0.011
YHR035W	hypothetical protein	0.011
RPI1	Rpi1p	0.011
PUT4	Put4p	0.011
YLR445W	hypothetical protein	0.011
YLR281C	hypothetical protein	0.011
ECM27	Ecm27p	0.011
PZF1	Pzf1p	0.011
COS12	Cos12p	0.011
YPR096C	hypothetical protein	0.011
YCR050C	hypothetical protein	0.011
YLR225C	hypothetical protein	0.010
YNL067W-B	hypothetical protein	0.010
YOR387C	hypothetical protein	0.010
YCR102C	hypothetical protein	0.010
PHM6	Phm6p	0.010
HMRA1	Hmra1p	0.010
SPR6	Spr6p	0.010
APL1	Apl1p	0.010
YML100W-A	hypothetical protein	0.010
DUR1,2	Dur1,2p	0.010
DTR1	Dtr1p	0.010
POP6	Pop6p	0.010
YNL162W-A	hypothetical protein	0.010
SPO19	Spo19p	0.010
YJR120W	hypothetical protein	0.010
SAP4	Sap4p	0.010
YPR153W	hypothetical protein	0.010