IMP

Process View

Saccharomyces cerevisiae

27 genes annotated in yeast

negative regulation of protein catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CDC55	Cdc55p	0.670
CDC20	Cdc20p	0.661
PPH22	Pph22p	0.616
PPH21	Pph21p	0.586
MAD2	Mad2p	0.526
HHF2	Hhf2p	0.511
CSE4	Cse4p	0.446
RTS1	Rts1p	0.312
CTF13	Ctf13p	0.257
PPZ1	Ppz1p	0.254
SLK19	Slk19p	0.237
MAD3	Mad3p	0.215
CHL4	Chl4p	0.214
MAD1	Mad1p	0.200
MTW1	Mtw1p	0.150
KIP1	Kip1p	0.149
ZDS1	Zds1p	0.125
MLC1	Mlc1p	0.120
NBL1	Nbl1p	0.119
YPI1	Ypi1p	0.116
IML3	Iml3p	0.110
BUB3	Bub3p	0.108	Worm Fly
SLI15	Sli15p	0.098
CTF3	Ctf3p	0.094
BUB1	Bub1p	0.093
SDS22	Sds22p	0.083
NSL1	Nsl1p	0.079
MCM21	Mcm21p	0.077
HTA1	Hta1p	0.050
EAF1	Eaf1p	0.050
TIP41	Tip41p	0.045
STE4	Ste4p	0.045
HTB1	Htb1p	0.042
DAM1	Dam1p	0.042
SPC24	Spc24p	0.041
VIK1	Vik1p	0.040
PIG2	Pig2p	0.039	Yeast
UFD2	Ufd2p	0.039
RFA1	Rfa1p	0.038
YIL151C	hypothetical protein	0.038
IPL1	Ipl1p	0.037
SPO12	Spo12p	0.035
ASE1	Ase1p	0.034
FMP48	Fmp48p	0.034
KIN1	Kin1p	0.034
NTO1	Nto1p	0.033
YBP2	Ybp2p	0.033
YKL075C	hypothetical protein	0.032
CTF8	Ctf8p	0.031
SLG1	Slg1p	0.030
CDC28	Cdc28p	0.030
GLG1	Glg1p	0.029
PCL10	Pcl10p	0.029
SPC110	Spc110p	0.029
CIN1	Cin1p	0.029
PKC1	Pkc1p	0.029	Human
PTI1	Pti1p	0.028
SET2	Set2p	0.027
YML053C	hypothetical protein	0.027
GIP2	Gip2p	0.027	Yeast
BET5	Bet5p	0.027
SPC105	Spc105p	0.026
SRD1	Srd1p	0.026
YGL010W	hypothetical protein	0.026
HHT1	Hht1p	0.025	Yeast
YNL144C	hypothetical protein	0.025
JLP2	Jlp2p	0.025
ATG27	Atg27p	0.024
PDR15	Pdr15p	0.024
STD1	Std1p	0.024
DSN1	Dsn1p	0.024
SMC5	Smc5p	0.024
TRA1	Tra1p	0.024
YOL038C-A	hypothetical protein	0.024
PLC1	Plc1p	0.024
YLR162W	hypothetical protein	0.024
RMD5	Rmd5p	0.023
LEU2	Leu2p	0.023
SWC4	Swc4p	0.023
SAP4	Sap4p	0.023
YLR264C-A	hypothetical protein	0.023
SMC4	Smc4p	0.023
VHS2	Vhs2p	0.023
CBF1	Cbf1p	0.022
CAB3	Cab3p	0.022
STU1	Stu1p	0.022
CAR1	Car1p	0.022
MER1	Mer1p	0.022
HST3	Hst3p	0.022
ARG8	Arg8p	0.021
HIT1	Hit1p	0.021
MEC1	Mec1p	0.021
YDL206W	hypothetical protein	0.021
SWC7	Swc7p	0.021
GLC7	Glc7p	0.021
TAF11	Taf11p	0.021
FRA2	Fra2p	0.021
SFI1	Sfi1p	0.021
YNR014W	hypothetical protein	0.021
CIN8	Cin8p	0.021
RAD54	Rad54p	0.021
LIF1	Lif1p	0.021
PRS2	Prs2p	0.020
GAC1	Gac1p	0.020
RCO1	Rco1p	0.020
YOR131C	hypothetical protein	0.020
CTI6	Cti6p	0.020
CCT2	Cct2p	0.019
SPL2	Spl2p	0.019
NGG1	Ngg1p	0.019
PPQ1	Ppq1p	0.019	Yeast
RAD61	Rad61p	0.019
PNS1	Pns1p	0.019
URA3	Ura3p	0.019
SYN8	Syn8p	0.019
CDC37	Cdc37p	0.018
TPI1	Tpi1p	0.018
YIR035C	hypothetical protein	0.018
ZPS1	Zps1p	0.018
NDD1	Ndd1p	0.018
MIF2	Mif2p	0.018
MYO1	Myo1p	0.018
ATG20	Atg20p	0.018
UPS3	Ups3p	0.018
TAF8	Taf8p	0.018
CUP1-1	Cup1-1p	0.018
CLB1	Clb1p	0.018
ARR2	Arr2p	0.018
TOR2	Tor2p	0.018
HYM1	Hym1p	0.018
SET4	Set4p	0.017
CPD1	Cpd1p	0.017
YLR042C	hypothetical protein	0.017
SPO14	Spo14p	0.017
KIN3	Kin3p	0.017
HXT3	Hxt3p	0.017
SRO77	Sro77p	0.017
BRN1	Brn1p	0.017
RPT1	Rpt1p	0.017
PFS2	Pfs2p	0.017
SLX8	Slx8p	0.017
HPF1	Hpf1p	0.017
YNR062C	hypothetical protein	0.017
PSP1	Psp1p	0.017
YAR068W	hypothetical protein	0.017
QNS1	Qns1p	0.017
YPL225W	hypothetical protein	0.017
SIS2	Sis2p	0.017
CRP1	Crp1p	0.017
OPT2	Opt2p	0.017
YGK3	Ygk3p	0.017
YBR296C-A	hypothetical protein	0.017
GSY1	Gsy1p	0.017
SWD3	Swd3p	0.017
TOP2	Top2p	0.017
RAD23	Rad23p	0.017
YPR157W	hypothetical protein	0.016
MRK1	Mrk1p	0.016
PKH3	Pkh3p	0.016
PCT1	Pct1p	0.016
HHO1	Hho1p	0.016
PMA2	Pma2p	0.016
AUA1	Aua1p	0.016
IRC15	Irc15p	0.016
ARP10	Arp10p	0.016
CHA1	Cha1p	0.016
ADH2	Adh2p	0.016
ATP6	Atp6p	0.016
YOL013W-A	hypothetical protein	0.016
YLR407W	hypothetical protein	0.016
SPS4	Sps4p	0.016
YDL012C	hypothetical protein	0.016
SEC15	Sec15p	0.016
WSS1	Wss1p	0.016
PTR2	Ptr2p	0.016
YBR013C	hypothetical protein	0.015
RHO1	Rho1p	0.015
OSH3	Osh3p	0.015
BCK2	Bck2p	0.015
SPC25	Spc25p	0.015
EST2	Est2p	0.015
PZF1	Pzf1p	0.015
ICS2	Ics2p	0.015
ESP1	Esp1p	0.015
LCB4	Lcb4p	0.015
BDF2	Bdf2p	0.015
TAF13	Taf13p	0.015
REE1	Ree1p	0.015
PRP16	Prp16p	0.015
SUR1	Sur1p	0.015
OPY1	Opy1p	0.015
KEL2	Kel2p	0.015
ESC1	Esc1p	0.015
PSK1	Psk1p	0.015
BNA4	Bna4p	0.015
APM2	Apm2p	0.015
VPS5	Vps5p	0.015
YOR283W	hypothetical protein	0.015
FAU1	Fau1p	0.015
BIT61	Bit61p	0.015
TPD3	Tpd3p	0.015
IKI1	Iki1p	0.015
THG1	Thg1p	0.015
MF(ALPHA)2	Mf(alpha)2p	0.015
BFA1	Bfa1p	0.015
CRZ1	Crz1p	0.015
YOR352W	hypothetical protein	0.015
NKP2	Nkp2p	0.015
YJR115W	hypothetical protein	0.015
IZH4	Izh4p	0.014
GIP3	Gip3p	0.014
FMT1	Fmt1p	0.014
YHR033W	hypothetical protein	0.014
CDC15	Cdc15p	0.014
TYE7	Tye7p	0.014
CHL1	Chl1p	0.014
YGL082W	hypothetical protein	0.014
MND1	Mnd1p	0.014
YBL029W	hypothetical protein	0.014
UBC9	Ubc9p	0.014
AMA1	Ama1p	0.014
TGL2	Tgl2p	0.014
YCR090C	hypothetical protein	0.014
ARO10	Aro10p	0.014
YNL058C	hypothetical protein	0.014
TAF10	Taf10p	0.014
DIC1	Dic1p	0.014
MPS1	Mps1p	0.014
AAD6	Aad6p	0.014
YAL037C-A	hypothetical protein	0.014
YJL147C	hypothetical protein	0.014
YKR075C	hypothetical protein	0.014
BAT2	Bat2p	0.014
HHT2	Hht2p	0.014
BSC1	Bsc1p	0.014
UFD1	Ufd1p	0.014
YML003W	hypothetical protein	0.014
MCM22	Mcm22p	0.014
YGR035C	hypothetical protein	0.013
DIF1	Dif1p	0.013
YJR120W	hypothetical protein	0.013
YHP1	Yhp1p	0.013
NCE103	Nce103p	0.013
YPR117W	hypothetical protein	0.013
YPR096C	hypothetical protein	0.013
NRG2	Nrg2p	0.013
MFA2	Mfa2p	0.013
GYL1	Gyl1p	0.013
YNL033W	hypothetical protein	0.013
SSU72	Ssu72p	0.013
FPK1	Fpk1p	0.013
APM1	Apm1p	0.013
OKP1	Okp1p	0.013
YDL085C-A	hypothetical protein	0.013
WSC3	Wsc3p	0.013
YCR102C	hypothetical protein	0.013
TAF4	Taf4p	0.013
TID3	Tid3p	0.013
YLR281C	hypothetical protein	0.013
YCH1	Ych1p	0.013
YLR445W	hypothetical protein	0.013
TIM12	Tim12p	0.013
THP3	Thp3p	0.013
PUF2	Puf2p	0.013
RPT6	Rpt6p	0.013
ENA5	Ena5p	0.013
ISU2	Isu2p	0.013
YBR096W	hypothetical protein	0.013
HOR2	Hor2p	0.013
YAR066W	hypothetical protein	0.013
UTR4	Utr4p	0.013
MPH1	Mph1p	0.012
HMRA2	Hmra2p	0.012
YLR040C	hypothetical protein	0.012
APL3	Apl3p	0.012
RAM2	Ram2p	0.012
GPX2	Gpx2p	0.012
HO	Hop	0.012
RRD2	Rrd2p	0.012
IML1	Iml1p	0.012
CMK1	Cmk1p	0.012
RNP1	Rnp1p	0.012
YNL067W-B	hypothetical protein	0.012
LCL1	Lcl1p	0.012
YDR034C-A	hypothetical protein	0.012
STE18	Ste18p	0.012
YAL064W	hypothetical protein	0.012
YGL006W-A	hypothetical protein	0.012
GCV1	Gcv1p	0.012
YPL067C	hypothetical protein	0.012
MET8	Met8p	0.012
VPS54	Vps54p	0.012
YMR317W	hypothetical protein	0.012
YNL260C	hypothetical protein	0.012
YNL234W	hypothetical protein	0.012
YDL186W	hypothetical protein	0.012
CWP2	Cwp2p	0.012
PRP28	Prp28p	0.012
MEI5	Mei5p	0.012
YDR222W	hypothetical protein	0.012
MGS1	Mgs1p	0.012
BIO2	Bio2p	0.012
SMC6	Smc6p	0.012
PHM6	Phm6p	0.012
ULA1	Ula1p	0.012
RTT105	Rtt105p	0.012
AQY2	Aqy2p	0.012
MF(ALPHA)1	Mf(alpha)1p	0.012
YKL069W	hypothetical protein	0.012
YLR460C	hypothetical protein	0.012
AQR1	Aqr1p	0.012
YEA6	Yea6p	0.012
CTR3	Ctr3p	0.012
ECT1	Ect1p	0.012
RRN5	Rrn5p	0.012
EEB1	Eeb1p	0.012
YIP4	Yip4p	0.012
CTS1	Cts1p	0.012
RAD53	Rad53p	0.012
PRM4	Prm4p	0.012
HDA2	Hda2p	0.012
CDC24	Cdc24p	0.012
TOF2	Tof2p	0.012
YIR042C	hypothetical protein	0.012
YJL160C	hypothetical protein	0.012
YCR050C	hypothetical protein	0.012
POP6	Pop6p	0.012
MMP1	Mmp1p	0.012
YPR027C	hypothetical protein	0.012
YNL190W	hypothetical protein	0.012
JJJ3	Jjj3p	0.012
TPM2	Tpm2p	0.011
RPT4	Rpt4p	0.011
YPT10	Ypt10p	0.011
SCM4	Scm4p	0.011
SGE1	Sge1p	0.011
HAL5	Hal5p	0.011
YLR108C	hypothetical protein	0.011
GSY2	Gsy2p	0.011
FRE5	Fre5p	0.011
ERV2	Erv2p	0.011
YPL068C	hypothetical protein	0.011
YKR045C	hypothetical protein	0.011
ECM27	Ecm27p	0.011
YOR060C	hypothetical protein	0.011
RNH1	Rnh1p	0.011
DUR1,2	Dur1,2p	0.011
SWI5	Swi5p	0.011
YJL218W	hypothetical protein	0.011
YAR029W	hypothetical protein	0.011
BET4	Bet4p	0.011
VBA5	Vba5p	0.011
YPT7	Ypt7p	0.011
RPI1	Rpi1p	0.011
SKM1	Skm1p	0.011
YBP1	Ybp1p	0.011
SRX1	Srx1p	0.011
YNL162W-A	hypothetical protein	0.011
YFR057W	hypothetical protein	0.011
YOL014W	hypothetical protein	0.011
YJL181W	hypothetical protein	0.011
YNL018C	hypothetical protein	0.011
TFG1	Tfg1p	0.011
YML100W-A	hypothetical protein	0.011
YER186C	hypothetical protein	0.011
CTA1	Cta1p	0.011
TIR3	Tir3p	0.011
DAL82	Dal82p	0.011
RMD6	Rmd6p	0.011
YOR059C	hypothetical protein	0.011
MET12	Met12p	0.011
WSC4	Wsc4p	0.011
HUR1	Hur1p	0.011
OYE3	Oye3p	0.011
YPL216W	hypothetical protein	0.011
YKR041W	hypothetical protein	0.011
YPR159C-A	hypothetical protein	0.011
BDS1	Bds1p	0.011
MOB1	Mob1p	0.011
YAR028W	hypothetical protein	0.011
AAD15	Aad15p	0.011
HUL5	Hul5p	0.011
IZH3	Izh3p	0.011
SSP1	Ssp1p	0.011
YOR012W	hypothetical protein	0.011
TAF12	Taf12p	0.011
ALT2	Alt2p	0.011
YLR278C	hypothetical protein	0.011
PBP2	Pbp2p	0.011
HMRA1	Hmra1p	0.011
MTH1	Mth1p	0.011
PUT4	Put4p	0.011
COS12	Cos12p	0.011
RRT5	Rrt5p	0.011
FCY22	Fcy22p	0.011
APL1	Apl1p	0.011
YGR205W	hypothetical protein	0.011
RIB7	Rib7p	0.011
MAM1	Mam1p	0.011
FOL3	Fol3p	0.011
COQ2	Coq2p	0.011
MDJ2	Mdj2p	0.011
YEL023C	hypothetical protein	0.011
PRE10	Pre10p	0.011
SPO22	Spo22p	0.011
HNT1	Hnt1p	0.011
YMR295C	hypothetical protein	0.010
SPC42	Spc42p	0.010
SFT1	Sft1p	0.010
DCI1	Dci1p	0.010
YLR412C-A	hypothetical protein	0.010
YBL044W	hypothetical protein	0.010
COS6	Cos6p	0.010
YJL107C	hypothetical protein	0.010
YPR015C	hypothetical protein	0.010
YER039C-A	hypothetical protein	0.010
YSR3	Ysr3p	0.010
CWC24	Cwc24p	0.010
BSC2	Bsc2p	0.010
VHS3	Vhs3p	0.010
OAF1	Oaf1p	0.010
YOR387C	hypothetical protein	0.010
ECM30	Ecm30p	0.010
BRE2	Bre2p	0.010
GRX8	Grx8p	0.010
ARO9	Aro9p	0.010
AIF1	Aif1p	0.010
YPL272C	hypothetical protein	0.010
PHD1	Phd1p	0.010
YLR342W-A	hypothetical protein	0.010
DNL4	Dnl4p	0.010
YCL001W-B	hypothetical protein	0.010
SCC2	Scc2p	0.010
YOR338W	hypothetical protein	0.010
YMR122W-A	hypothetical protein	0.010
DOG1	Dog1p	0.010
YKL106C-A	hypothetical protein	0.010
GNA1	Gna1p	0.010
KSH1	Ksh1p	0.010
TAH1	Tah1p	0.010
MPH3	Mph3p	0.010
YIP1	Yip1p	0.010
CAB4	Cab4p	0.010
EDC1	Edc1p	0.010
SPT20	Spt20p	0.010
CDC1	Cdc1p	0.010
YHR177W	hypothetical protein	0.010
RMI1	Rmi1p	0.010
YAT1	Yat1p	0.010
ARE2	Are2p	0.010