IMP

Process View

Saccharomyces cerevisiae

42 genes annotated in yeast

dna duplex unwinding

The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.

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In addition to gene-name show these genes:

Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna duplex unwinding"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dna duplex unwinding" (in gray)

Name	Description	Probability	Func Analog Organism
MCM4	Mcm4p	0.924
MCM2	Mcm2p	0.787
PSF2	Psf2p	0.730
MCM6	Mcm6p	0.628
MCM7	Mcm7p	0.535
MCM10	Mcm10p	0.454
SLD5	Sld5p	0.308	Fly
MCM3	Mcm3p	0.292
RAD52	Rad52p	0.279
SMC2	Smc2p	0.267
BRN1	Brn1p	0.254
MEC1	Mec1p	0.252
SLD2	Sld2p	0.221
DNA2	Dna2p	0.203
RFA2	Rfa2p	0.180
MCM5	Mcm5p	0.165
RFA1	Rfa1p	0.164
CTF4	Ctf4p	0.152
SMC3	Smc3p	0.151
PSP2	Psp2p	0.150
RAD53	Rad53p	0.150
SMC4	Smc4p	0.115
YOR060C	hypothetical protein	0.106
CDC45	Cdc45p	0.092	Fly
RAD50	Rad50p	0.088
UBP1	Ubp1p	0.076
TOF1	Tof1p	0.072
MRC1	Mrc1p	0.066
PSF1	Psf1p	0.064	Fly
IRR1	Irr1p	0.063
YCG1	Ycg1p	0.062
SCC2	Scc2p	0.060
TAH11	Tah11p	0.059
DBF4	Dbf4p	0.057
YCS4	Ycs4p	0.056
CSM3	Csm3p	0.049
ALG14	Alg14p	0.049
DPB11	Dpb11p	0.049
SMC1	Smc1p	0.039
MPT5	Mpt5p	0.038
SGS1	Sgs1p	0.038
PDC2	Pdc2p	0.036
KEM1	Kem1p	0.036
INO80	Ino80p	0.036
MSH3	Msh3p	0.036
CDC6	Cdc6p	0.034
ARP4	Arp4p	0.034
HST3	Hst3p	0.033
DSS1	Dss1p	0.032
RTT107	Rtt107p	0.032
RAD5	Rad5p	0.030
MSH6	Msh6p	0.030
SRD1	Srd1p	0.030
PRS2	Prs2p	0.029
TOR2	Tor2p	0.028
RMI1	Rmi1p	0.028
TOP3	Top3p	0.027
MOT1	Mot1p	0.027
YAR068W	hypothetical protein	0.026
LEU2	Leu2p	0.025
YLR264C-A	hypothetical protein	0.025
YLR162W	hypothetical protein	0.024
YIR035C	hypothetical protein	0.024
YOL038C-A	hypothetical protein	0.024
RFC4	Rfc4p	0.023
ACM1	Acm1p	0.023
MER1	Mer1p	0.023
SSL1	Ssl1p	0.023
FAA2	Faa2p	0.022
HXT3	Hxt3p	0.022
TEL1	Tel1p	0.022
YHB1	Yhb1p	0.022
SMC6	Smc6p	0.022
POL2	Pol2p	0.022
URA3	Ura3p	0.021
PSF3	Psf3p	0.021	Fly
SEN34	Sen34p	0.021
SEN54	Sen54p	0.021
HHT2	Hht2p	0.021
ATP6	Atp6p	0.021
YBL044W	hypothetical protein	0.020
ZPS1	Zps1p	0.020
SPO22	Spo22p	0.020
MSA2	Msa2p	0.020
ALT2	Alt2p	0.020
IES1	Ies1p	0.020
COS12	Cos12p	0.020
YAR066W	hypothetical protein	0.020
NUP157	Nup157p	0.019
YER039C-A	hypothetical protein	0.019
FMP25	Fmp25p	0.019
TAO3	Tao3p	0.019
YPR157W	hypothetical protein	0.019
CUP1-1	Cup1-1p	0.019
BSC1	Bsc1p	0.019
YLR042C	hypothetical protein	0.019
YBR013C	hypothetical protein	0.019
EST2	Est2p	0.019
SPL2	Spl2p	0.019
STU1	Stu1p	0.019
RKM1	Rkm1p	0.018
ICS2	Ics2p	0.018
SRS2	Srs2p	0.018
YIL151C	hypothetical protein	0.018
GCN2	Gcn2p	0.018
RFC5	Rfc5p	0.018
YJL181W	hypothetical protein	0.018
HPF1	Hpf1p	0.018
TAF2	Taf2p	0.017
YDL156W	hypothetical protein	0.017
MSS116	Mss116p	0.017
YOL013W-A	hypothetical protein	0.017
YLR419W	hypothetical protein	0.017
AUA1	Aua1p	0.017
MMS22	Mms22p	0.017
DCG1	Dcg1p	0.017
SPC105	Spc105p	0.017
ORC4	Orc4p	0.017
NBL1	Nbl1p	0.017
YLF2	Ylf2p	0.016
FAA3	Faa3p	0.016
MF(ALPHA)2	Mf(alpha)2p	0.016
CPD1	Cpd1p	0.016
SPS4	Sps4p	0.016
AZF1	Azf1p	0.016
SWC7	Swc7p	0.016
FMT1	Fmt1p	0.016
PTR2	Ptr2p	0.016
PBY1	Pby1p	0.016
ARP10	Arp10p	0.016
ARG8	Arg8p	0.016
AAD15	Aad15p	0.016
BNA4	Bna4p	0.016
CHA1	Cha1p	0.016
RTT105	Rtt105p	0.016
ZDS2	Zds2p	0.016
DPB2	Dpb2p	0.016
YLL066C	hypothetical protein	0.015
OPT2	Opt2p	0.015
RAD54	Rad54p	0.015
BLM10	Blm10p	0.015
YML003W	hypothetical protein	0.015
YBR235W	hypothetical protein	0.015
MRH4	Mrh4p	0.015	Yeast
YPR096C	hypothetical protein	0.015
YAL037C-A	hypothetical protein	0.015
RRN5	Rrn5p	0.015
YKR075C	hypothetical protein	0.015
SRX1	Srx1p	0.015
MFA2	Mfa2p	0.015
YNL234W	hypothetical protein	0.015
SPT16	Spt16p	0.015
BIO2	Bio2p	0.015
TSC3	Tsc3p	0.015
YAL064W	hypothetical protein	0.015
SCM4	Scm4p	0.014
HOR2	Hor2p	0.014
UPS3	Ups3p	0.014
HTA2	Hta2p	0.014
REE1	Ree1p	0.014
FIR1	Fir1p	0.014
ECO1	Eco1p	0.014
YER186C	hypothetical protein	0.014
KTR5	Ktr5p	0.014
DUR1,2	Dur1,2p	0.014
YJR120W	hypothetical protein	0.014
RAD51	Rad51p	0.014	Human
BDS1	Bds1p	0.014
MIG2	Mig2p	0.014
DIC1	Dic1p	0.014
IZH4	Izh4p	0.014
YGL006W-A	hypothetical protein	0.014
SMC5	Smc5p	0.014
TIR3	Tir3p	0.014
YGR266W	hypothetical protein	0.014
NOP10	Nop10p	0.014
HO	Hop	0.014
CCH1	Cch1p	0.014
YBL029W	hypothetical protein	0.014
YDL218W	hypothetical protein	0.014
MSH5	Msh5p	0.014
YMR317W	hypothetical protein	0.014
AQY2	Aqy2p	0.014
RNP1	Rnp1p	0.013
ARP9	Arp9p	0.013
CTS1	Cts1p	0.013
HXT2	Hxt2p	0.013
YPL216W	hypothetical protein	0.013
CIN2	Cin2p	0.013
YLR040C	hypothetical protein	0.013
OPT1	Opt1p	0.013
RAD59	Rad59p	0.013
CSM1	Csm1p	0.013
FCY21	Fcy21p	0.013
YNL067W-B	hypothetical protein	0.013
YLR412C-A	hypothetical protein	0.013
YPL067C	hypothetical protein	0.013
YGR035C	hypothetical protein	0.013
YPL272C	hypothetical protein	0.013
MRH1	Mrh1p	0.013
YPR027C	hypothetical protein	0.013
MAM1	Mam1p	0.013
DIF1	Dif1p	0.013
YDR034C-A	hypothetical protein	0.013
NRG2	Nrg2p	0.013
RAD55	Rad55p	0.013
PMA2	Pma2p	0.013
YIR042C	hypothetical protein	0.013
ESP1	Esp1p	0.013
YGL235W	hypothetical protein	0.013
BEM3	Bem3p	0.013
MF(ALPHA)1	Mf(alpha)1p	0.013
LCL1	Lcl1p	0.012
YDR222W	hypothetical protein	0.012
RRT5	Rrt5p	0.012
SAM3	Sam3p	0.012
ENA5	Ena5p	0.012
KOG1	Kog1p	0.012
CAB2	Cab2p	0.012
PRP31	Prp31p	0.012
TOS4	Tos4p	0.012
FCY22	Fcy22p	0.012
YNL033W	hypothetical protein	0.012
HEM12	Hem12p	0.012
IMA5	Ima5p	0.012
AAD6	Aad6p	0.012
APT2	Apt2p	0.012
YML100W-A	hypothetical protein	0.012
VIK1	Vik1p	0.012
YNL018C	hypothetical protein	0.012
GNA1	Gna1p	0.012
SUA7	Sua7p	0.012
HSH155	Hsh155p	0.012
SNU23	Snu23p	0.012
PRM7	Prm7p	0.012
CTR3	Ctr3p	0.012
YKL187C	hypothetical protein	0.012
YCR102C	hypothetical protein	0.012
KSH1	Ksh1p	0.012
YJL160C	hypothetical protein	0.012
SSP1	Ssp1p	0.012
SFT1	Sft1p	0.012
SCY1	Scy1p	0.012
SET4	Set4p	0.012
STE6	Ste6p	0.012
YNR063W	hypothetical protein	0.012
KNH1	Knh1p	0.012
SLD3	Sld3p	0.012
YNL162W-A	hypothetical protein	0.012
GYL1	Gyl1p	0.012
ORC6	Orc6p	0.012
SSA3	Ssa3p	0.012
YLR342W-A	hypothetical protein	0.011
PCL9	Pcl9p	0.011
SGE1	Sge1p	0.011
BIO5	Bio5p	0.011
TYE7	Tye7p	0.011
RED1	Red1p	0.011
ADH2	Adh2p	0.011
HUG1	Hug1p	0.011
YHR035W	hypothetical protein	0.011
YNR062C	hypothetical protein	0.011
YHR177W	hypothetical protein	0.011
YSR3	Ysr3p	0.011
YDR524W-C	hypothetical protein	0.011
GCV2	Gcv2p	0.011
SWM2	Swm2p	0.011
YCL001W-B	hypothetical protein	0.011
YOR387C	hypothetical protein	0.011
NEO1	Neo1p	0.011
YAT1	Yat1p	0.011
CBP1	Cbp1p	0.011
RKR1	Rkr1p	0.011
RNR3	Rnr3p	0.011
YBL107C	hypothetical protein	0.011
ICS3	Ics3p	0.011
RAD9	Rad9p	0.011
OCT1	Oct1p	0.011
PHO11	Pho11p	0.011
IMA2	Ima2p	0.011
SOV1	Sov1p	0.011
PHM6	Phm6p	0.011
HAP1	Hap1p	0.011
SAP1	Sap1p	0.011
DAD3	Dad3p	0.011
YCH1	Ych1p	0.011
DCP1	Dcp1p	0.011
YGR126W	hypothetical protein	0.011
FRE5	Fre5p	0.011
YMR244W	hypothetical protein	0.011
HEM3	Hem3p	0.011
AAP1	Aap1p	0.011
MET8	Met8p	0.011
SIT1	Sit1p	0.011
RSN1	Rsn1p	0.011
YOL014W	hypothetical protein	0.011
MMP1	Mmp1p	0.011
YJL107C	hypothetical protein	0.011
GIS3	Gis3p	0.011
YKL070W	hypothetical protein	0.011
HST2	Hst2p	0.011
PET127	Pet127p	0.011
YHK8	Yhk8p	0.011
YKR045C	hypothetical protein	0.011
SRT1	Srt1p	0.011
GLT1	Glt1p	0.011
YPL277C	hypothetical protein	0.011
KIP1	Kip1p	0.011
PDR16	Pdr16p	0.011
YGR067C	hypothetical protein	0.011
YMR086W	hypothetical protein	0.011
DSE3	Dse3p	0.011
DAK2	Dak2p	0.011
DOP1	Dop1p	0.011
YMR122W-A	hypothetical protein	0.011
RFA3	Rfa3p	0.011
YNL034W	hypothetical protein	0.011
YKL106C-A	hypothetical protein	0.011
SPP381	Spp381p	0.011
YPR159C-A	hypothetical protein	0.011
MAS1	Mas1p	0.011
SSL2	Ssl2p	0.011
YML081W	hypothetical protein	0.011
SBE22	Sbe22p	0.011
SCT1	Sct1p	0.011
STB1	Stb1p	0.011
PCH2	Pch2p	0.010
KRE29	Kre29p	0.010
TIP1	Tip1p	0.010
SPC97	Spc97p	0.010
YMR001C-A	hypothetical protein	0.010
YCF1	Ycf1p	0.010
MPH3	Mph3p	0.010
BAT2	Bat2p	0.010
YLR406C-A	hypothetical protein	0.010
SEO1	Seo1p	0.010
ARR2	Arr2p	0.010
PRM4	Prm4p	0.010
YFL051C	hypothetical protein	0.010
YER175W-A	hypothetical protein	0.010
BTT1	Btt1p	0.010
TFC8	Tfc8p	0.010
ARO10	Aro10p	0.010
GLN1	Gln1p	0.010
SRC1	Src1p	0.010
MRM1	Mrm1p	0.010
POL30	Pol30p	0.010
GFA1	Gfa1p	0.010
DOG1	Dog1p	0.010
MTO1	Mto1p	0.010
YKR041W	hypothetical protein	0.010
YOR316C-A	hypothetical protein	0.010
VBA5	Vba5p	0.010
SOR2	Sor2p	0.010
FRE7	Fre7p	0.010
YBR219C	hypothetical protein	0.010
YRF1-6	Yrf1-6p	0.010
YLR126C	hypothetical protein	0.010
YNL097C-B	hypothetical protein	0.010
YNL058C	hypothetical protein	0.010