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Saccharomyces cerevisiae

6 genes annotated in yeast

tricarboxylic acid cycle

A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

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In addition to gene-name show these genes:

Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tricarboxylic acid cycle"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tricarboxylic acid cycle" (in gray)

Name	Description	Probability	Func Analog Organism
FUM1	Fum1p	0.252
CIT1	Cit1p	0.246
MDH1	Mdh1p	0.133
IDH1	Idh1p	0.111	Rat
IDH2	Idh2p	0.107	Rat
SDH1	Sdh1p	0.097
SDH4	Sdh4p	0.043	Human
LEU2	Leu2p	0.032
LPD1	Lpd1p	0.030
ACH1	Ach1p	0.026
SDH3	Sdh3p	0.025
YFH1	Yfh1p	0.024
MDH2	Mdh2p	0.020
SDH2	Sdh2p	0.018
RIP1	Rip1p	0.017
PDH1	Pdh1p	0.016
ECM13	Ecm13p	0.016
SRD1	Srd1p	0.014
ATP3	Atp3p	0.013
ARP10	Arp10p	0.012
BAT2	Bat2p	0.012
CUP1-1	Cup1-1p	0.012
YOL038C-A	hypothetical protein	0.012
YLR264C-A	hypothetical protein	0.012
ACO1	Aco1p	0.012
MIR1	Mir1p	0.012
MER1	Mer1p	0.011
ERG10	Erg10p	0.010
YLR162W	hypothetical protein	0.010
COX6	Cox6p	0.010
SPL2	Spl2p	0.010
ARG8	Arg8p	0.010
MF(ALPHA)2	Mf(alpha)2p	0.010