IMP

Process View

Saccharomyces cerevisiae

33 genes annotated in yeast

Multi-species View

negative regulation of protein processing

GO:0010955

Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein processing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of protein processing" (in gray)

Name	Description	Probability	Func Analog Organism
CDC55	Cdc55p	0.800
PPH22	Pph22p	0.665
CTF13	Ctf13p	0.569
RTS1	Rts1p	0.543
MAD2	Mad2p	0.401
PPH21	Pph21p	0.332
IML3	Iml3p	0.297
CBF1	Cbf1p	0.279
CDC20	Cdc20p	0.260
BUB3	Bub3p	0.205	Worm Fly
HHF2	Hhf2p	0.201
STI1	Sti1p	0.173
YPI1	Ypi1p	0.160
MAD3	Mad3p	0.154
MCM21	Mcm21p	0.139
GLC7	Glc7p	0.131
GIP2	Gip2p	0.122	Yeast
PSP2	Psp2p	0.111
TIP41	Tip41p	0.106
KIP1	Kip1p	0.104
MAD1	Mad1p	0.092
MLC1	Mlc1p	0.088
SLK19	Slk19p	0.084
NKP2	Nkp2p	0.071
SKP1	Skp1p	0.071
PPZ1	Ppz1p	0.070
SDS22	Sds22p	0.068
CKB1	Ckb1p	0.066
BCK1	Bck1p	0.065
HHT1	Hht1p	0.061	Yeast
HTA1	Hta1p	0.060
WWM1	Wwm1p	0.057
CHL4	Chl4p	0.056
NSL1	Nsl1p	0.054
CTF3	Ctf3p	0.051
PIG2	Pig2p	0.050	Yeast
SPC24	Spc24p	0.047
GAC1	Gac1p	0.045
FMP48	Fmp48p	0.045
NBL1	Nbl1p	0.045
TAF5	Taf5p	0.044
TPD3	Tpd3p	0.043
CTF8	Ctf8p	0.042
RAD23	Rad23p	0.041
CSE4	Cse4p	0.041
TAF10	Taf10p	0.041
VPS5	Vps5p	0.039
SAP190	Sap190p	0.038
CMK1	Cmk1p	0.038
RHO1	Rho1p	0.037
REG1	Reg1p	0.037
ZDS1	Zds1p	0.036
YBP2	Ybp2p	0.035
IRC15	Irc15p	0.035
DAM1	Dam1p	0.035
RFA1	Rfa1p	0.034
SCC2	Scc2p	0.034
MTW1	Mtw1p	0.034
CAJ1	Caj1p	0.033
PAM1	Pam1p	0.033
SOL1	Sol1p	0.032
KIC1	Kic1p	0.032
APD1	Apd1p	0.031
CHK1	Chk1p	0.031
YLH47	Ylh47p	0.030
SAP155	Sap155p	0.030
AME1	Ame1p	0.029
CPR6	Cpr6p	0.029
MPH1	Mph1p	0.029
VIK1	Vik1p	0.029
PLC1	Plc1p	0.029
CDC28	Cdc28p	0.029
SKM1	Skm1p	0.028	Human
YPL225W	hypothetical protein	0.028
STU1	Stu1p	0.027
SPC110	Spc110p	0.027
CHC1	Chc1p	0.027
VHS3	Vhs3p	0.027
GAL83	Gal83p	0.027
DDI1	Ddi1p	0.027
STE4	Ste4p	0.027
ATG27	Atg27p	0.026
TAF11	Taf11p	0.026
UBC1	Ubc1p	0.026
BUB1	Bub1p	0.026
PSP1	Psp1p	0.026
GLG1	Glg1p	0.026
MPS1	Mps1p	0.026
NTA1	Nta1p	0.026
SLI15	Sli15p	0.026
FIN1	Fin1p	0.026
EAF1	Eaf1p	0.025
PCL10	Pcl10p	0.025
NGL2	Ngl2p	0.025
YLR407W	hypothetical protein	0.024
AQR1	Aqr1p	0.023
CHL1	Chl1p	0.023
MAG1	Mag1p	0.022
MPT5	Mpt5p	0.022
ECO1	Eco1p	0.022
GNA1	Gna1p	0.022
YLR419W	hypothetical protein	0.022
YER039C-A	hypothetical protein	0.022
SRD1	Srd1p	0.021
MDM20	Mdm20p	0.021
OKP1	Okp1p	0.021
HTB1	Htb1p	0.021
ZPR1	Zpr1p	0.021
SMC4	Smc4p	0.021
YOL038C-A	hypothetical protein	0.021
ADH2	Adh2p	0.021
YIR016W	hypothetical protein	0.021
YLR162W	hypothetical protein	0.021
SWI5	Swi5p	0.021
MSS4	Mss4p	0.021
YDL119C	hypothetical protein	0.020
OSH3	Osh3p	0.020
CDC24	Cdc24p	0.020
YJL055W	hypothetical protein	0.020
BRN1	Brn1p	0.020
SFI1	Sfi1p	0.020
SSA3	Ssa3p	0.020
YLR264C-A	hypothetical protein	0.020
YGL036W	hypothetical protein	0.020
TID3	Tid3p	0.020
YBR085C-A	hypothetical protein	0.020
LEU2	Leu2p	0.019
AIM18	Aim18p	0.019
MDN1	Mdn1p	0.019
UFD2	Ufd2p	0.019
YGR235C	hypothetical protein	0.019
SPO12	Spo12p	0.019
TAF2	Taf2p	0.019
CTS1	Cts1p	0.019
RPT2	Rpt2p	0.019
REH1	Reh1p	0.018
PSH1	Psh1p	0.018
HIR1	Hir1p	0.018
IES1	Ies1p	0.018
MIA40	Mia40p	0.018
TAF7	Taf7p	0.018
CUP1-1	Cup1-1p	0.018
YPL068C	hypothetical protein	0.018
ESC1	Esc1p	0.018
CRP1	Crp1p	0.018
RGA2	Rga2p	0.018
ASE1	Ase1p	0.018
NCE103	Nce103p	0.018
YBR296C-A	hypothetical protein	0.018
CAB3	Cab3p	0.018
LSM12	Lsm12p	0.018
SAP4	Sap4p	0.018
MIF2	Mif2p	0.018
HST3	Hst3p	0.017
YLR225C	hypothetical protein	0.017
TKL2	Tkl2p	0.017
MER1	Mer1p	0.017
DNA2	Dna2p	0.017
ICS2	Ics2p	0.017
YDL012C	hypothetical protein	0.017
GPH1	Gph1p	0.017
GYL1	Gyl1p	0.017
MDM32	Mdm32p	0.017
RDH54	Rdh54p	0.017
YNL144C	hypothetical protein	0.017
NDD1	Ndd1p	0.017
YLR042C	hypothetical protein	0.017
PPQ1	Ppq1p	0.017	Yeast
UPS3	Ups3p	0.017
SPL2	Spl2p	0.017
IRC8	Irc8p	0.017
YNL234W	hypothetical protein	0.016
SEC15	Sec15p	0.016
AHP1	Ahp1p	0.016
RSC3	Rsc3p	0.016
FRA2	Fra2p	0.016
PBS2	Pbs2p	0.016
VIP1	Vip1p	0.016
ENT1	Ent1p	0.016
ARG8	Arg8p	0.016
OPY1	Opy1p	0.016
CDC7	Cdc7p	0.016
YNR062C	hypothetical protein	0.016
UBP11	Ubp11p	0.016
BAT2	Bat2p	0.016
YGL010W	hypothetical protein	0.016
ARR2	Arr2p	0.016
YIR035C	hypothetical protein	0.016
UBP8	Ubp8p	0.016
FOL3	Fol3p	0.016
ATP6	Atp6p	0.016
TGL2	Tgl2p	0.016
CHA1	Cha1p	0.016
YBR013C	hypothetical protein	0.016
CKB2	Ckb2p	0.016
CTR2	Ctr2p	0.016
STD1	Std1p	0.016
YAR068W	hypothetical protein	0.016
UFO1	Ufo1p	0.016
SRO77	Sro77p	0.015
RPT4	Rpt4p	0.015
IWR1	Iwr1p	0.015
LYP1	Lyp1p	0.015
LIF1	Lif1p	0.015
FAU1	Fau1p	0.015
RRP14	Rrp14p	0.015
CIN1	Cin1p	0.015
PAN1	Pan1p	0.015
YER163C	hypothetical protein	0.015
HHT2	Hht2p	0.015
HPF1	Hpf1p	0.015
PZF1	Pzf1p	0.015
PTR2	Ptr2p	0.015
PTC4	Ptc4p	0.015
SUT1	Sut1p	0.015
PPG1	Ppg1p	0.015	Yeast
NAT5	Nat5p	0.015
RRP40	Rrp40p	0.015
ZPS1	Zps1p	0.015
RKR1	Rkr1p	0.015
CPD1	Cpd1p	0.015
HHO1	Hho1p	0.015
KEL2	Kel2p	0.015
CYM1	Cym1p	0.015
TOS8	Tos8p	0.014
PRP28	Prp28p	0.014
HXT3	Hxt3p	0.014
URA3	Ura3p	0.014
NOB1	Nob1p	0.014
POG1	Pog1p	0.014
TPI1	Tpi1p	0.014
BCK2	Bck2p	0.014
RLP7	Rlp7p	0.014
YOR131C	hypothetical protein	0.014
CYC7	Cyc7p	0.014
DIF1	Dif1p	0.014
TOR2	Tor2p	0.014
AIM9	Aim9p	0.014
YML053C	hypothetical protein	0.014
AUA1	Aua1p	0.014
YTA12	Yta12p	0.014
PCT1	Pct1p	0.014
YGR205W	hypothetical protein	0.014
UBR1	Ubr1p	0.014
ALT2	Alt2p	0.014
CMD1	Cmd1p	0.014
SWI1	Swi1p	0.014
YKR075C	hypothetical protein	0.014
YOL013W-A	hypothetical protein	0.014
BUD8	Bud8p	0.014
YPR157W	hypothetical protein	0.014
BIO2	Bio2p	0.014
SPC105	Spc105p	0.013
SOK1	Sok1p	0.013
YIL151C	hypothetical protein	0.013
BSC1	Bsc1p	0.013
FYV8	Fyv8p	0.013
AAD15	Aad15p	0.013
SPS4	Sps4p	0.013
HMG2	Hmg2p	0.013
SET2	Set2p	0.013
BNA4	Bna4p	0.013
TSC3	Tsc3p	0.013
SRX1	Srx1p	0.013
PBP2	Pbp2p	0.013
NUD1	Nud1p	0.013
MRK1	Mrk1p	0.013
PRE6	Pre6p	0.013
YML003W	hypothetical protein	0.013
YLR281C	hypothetical protein	0.013
SHE1	She1p	0.013
AZF1	Azf1p	0.013
MF(ALPHA)2	Mf(alpha)2p	0.013
KIN1	Kin1p	0.013
GIC1	Gic1p	0.013
PCD1	Pcd1p	0.013
RFC5	Rfc5p	0.013
SGE1	Sge1p	0.013
COA4	Coa4p	0.013
HOR2	Hor2p	0.013
YLR108C	hypothetical protein	0.013
CDC37	Cdc37p	0.013
KTR5	Ktr5p	0.013
PBP1	Pbp1p	0.013
APM2	Apm2p	0.013
PKH3	Pkh3p	0.013
ECM22	Ecm22p	0.013
JLP2	Jlp2p	0.013
YIR014W	hypothetical protein	0.013
OPT2	Opt2p	0.013
FMT1	Fmt1p	0.013
YPL277C	hypothetical protein	0.013
DIC1	Dic1p	0.013
RRN7	Rrn7p	0.013
YPL168W	hypothetical protein	0.012
YGR079W	hypothetical protein	0.012
FAB1	Fab1p	0.012
YLR040C	hypothetical protein	0.012
CAB4	Cab4p	0.012
MEC1	Mec1p	0.012
AAD6	Aad6p	0.012
ECT1	Ect1p	0.012
ARO10	Aro10p	0.012
YAR066W	hypothetical protein	0.012
IML1	Iml1p	0.012
YBL029W	hypothetical protein	0.012
YAL037C-A	hypothetical protein	0.012
GSH2	Gsh2p	0.012
SWC3	Swc3p	0.012
TPM2	Tpm2p	0.012
YGR017W	hypothetical protein	0.012
YPR096C	hypothetical protein	0.012
YCR102C	hypothetical protein	0.012
COS111	Cos111p	0.012
NCS6	Ncs6p	0.012
MTM1	Mtm1p	0.012
PRP45	Prp45p	0.012
RRN5	Rrn5p	0.012
YFR045W	hypothetical protein	0.012
KIN3	Kin3p	0.012
ULA1	Ula1p	0.012
PTI1	Pti1p	0.012
YNR014W	hypothetical protein	0.012
POP6	Pop6p	0.012
NRG2	Nrg2p	0.012
KNS1	Kns1p	0.012
FAS2	Fas2p	0.012
RTS2	Rts2p	0.012
HIF1	Hif1p	0.012
ECM27	Ecm27p	0.012
VBA5	Vba5p	0.012
DCC1	Dcc1p	0.012
UFD1	Ufd1p	0.012
YMR317W	hypothetical protein	0.012
YJL181W	hypothetical protein	0.012
TYE7	Tye7p	0.012
RNP1	Rnp1p	0.012
YLR132C	hypothetical protein	0.012
YOR387C	hypothetical protein	0.012
PTC7	Ptc7p	0.012
YKL187C	hypothetical protein	0.012
PRE1	Pre1p	0.012
IPI1	Ipi1p	0.012
YNL067W-B	hypothetical protein	0.012
REE1	Ree1p	0.012
PIM1	Pim1p	0.012
EEB1	Eeb1p	0.012
YGK3	Ygk3p	0.012
YKL069W	hypothetical protein	0.012
PHM6	Phm6p	0.012
YMR074C	hypothetical protein	0.012
TIR3	Tir3p	0.012
YDR034C-A	hypothetical protein	0.012
OYE3	Oye3p	0.011
KCS1	Kcs1p	0.011
YGL006W-A	hypothetical protein	0.011
ERV2	Erv2p	0.011
MET8	Met8p	0.011
ARP10	Arp10p	0.011
SWC7	Swc7p	0.011
YAL064W	hypothetical protein	0.011
PMA2	Pma2p	0.011
PPN1	Ppn1p	0.011
MFA2	Mfa2p	0.011
NTO1	Nto1p	0.011
RPN7	Rpn7p	0.011
MF(ALPHA)1	Mf(alpha)1p	0.011
CUE2	Cue2p	0.011
ENA5	Ena5p	0.011
CDC15	Cdc15p	0.011
RTG2	Rtg2p	0.011
DUR1,2	Dur1,2p	0.011
RRT2	Rrt2p	0.011
YBL107C	hypothetical protein	0.011
GTS1	Gts1p	0.011
DCS2	Dcs2p	0.011
VPS75	Vps75p	0.011
ARE2	Are2p	0.011
YNL033W	hypothetical protein	0.011
YPL260W	hypothetical protein	0.011
NIT3	Nit3p	0.011
YNL018C	hypothetical protein	0.011
YLR445W	hypothetical protein	0.011
SWC4	Swc4p	0.011
IMA5	Ima5p	0.011
YCH1	Ych1p	0.011
WSC3	Wsc3p	0.011
YJR120W	hypothetical protein	0.011
PHD1	Phd1p	0.011
GLC8	Glc8p	0.011
PPX1	Ppx1p	0.011
YKR041W	hypothetical protein	0.011
YJL160C	hypothetical protein	0.011
HSH49	Hsh49p	0.011
YPR097W	hypothetical protein	0.011
TBS1	Tbs1p	0.011
YMR1	Ymr1p	0.011
YML100W-A	hypothetical protein	0.011
YLR412C-A	hypothetical protein	0.011
CDC53	Cdc53p	0.011
BOI2	Boi2p	0.011
AQY2	Aqy2p	0.011
SNF3	Snf3p	0.011
BDF2	Bdf2p	0.011
HO	Hop	0.011
LCL1	Lcl1p	0.011
TIP1	Tip1p	0.011
HAL5	Hal5p	0.011
RTT105	Rtt105p	0.011
FRE5	Fre5p	0.011
IZH4	Izh4p	0.011
YDL085C-A	hypothetical protein	0.011
YPL067C	hypothetical protein	0.011
TIM44	Tim44p	0.011
YIR042C	hypothetical protein	0.011
TAH11	Tah11p	0.011
YOL014W	hypothetical protein	0.011
YAR029W	hypothetical protein	0.011
GCV1	Gcv1p	0.011
EXO70	Exo70p	0.011
BIT61	Bit61p	0.011
STE18	Ste18p	0.011
YMR295C	hypothetical protein	0.011
THP3	Thp3p	0.011
MDJ2	Mdj2p	0.010
HSP78	Hsp78p	0.010
YJL107C	hypothetical protein	0.010
HMRA1	Hmra1p	0.010
YNL162W-A	hypothetical protein	0.010
ATO3	Ato3p	0.010
TFG2	Tfg2p	0.010
YMR122W-A	hypothetical protein	0.010
PNG1	Png1p	0.010
YPR153W	hypothetical protein	0.010
SAP185	Sap185p	0.010
GIP3	Gip3p	0.010
YBR096W	hypothetical protein	0.010
RMD6	Rmd6p	0.010
YDR222W	hypothetical protein	0.010
YPR027C	hypothetical protein	0.010
IRA1	Ira1p	0.010
OSM1	Osm1p	0.010
YEL1	Yel1p	0.010
YPL066W	hypothetical protein	0.010
CAR1	Car1p	0.010
BMH1	Bmh1p	0.010	Human
YPL113C	hypothetical protein	0.010
AIM11	Aim11p	0.010
MBF1	Mbf1p	0.010
MEI5	Mei5p	0.010
SRT1	Srt1p	0.010
HDA2	Hda2p	0.010
SIS2	Sis2p	0.010
RSN1	Rsn1p	0.010
YKR045C	hypothetical protein	0.010
YOR060C	hypothetical protein	0.010
SET4	Set4p	0.010
YML119W	hypothetical protein	0.010
AAD4	Aad4p	0.010
MTR2	Mtr2p	0.010
PRM7	Prm7p	0.010
YPR117W	hypothetical protein	0.010
IPL1	Ipl1p	0.010
YCL021W-A	hypothetical protein	0.010
SEO1	Seo1p	0.010
AIM14	Aim14p	0.010
UBR2	Ubr2p	0.010
TIM22	Tim22p	0.010
BDS1	Bds1p	0.010
MNN4	Mnn4p	0.010
QNS1	Qns1p	0.010
KNH1	Knh1p	0.010
PXA1	Pxa1p	0.010
ATR1	Atr1p	0.010
PRM4	Prm4p	0.010
IPT1	Ipt1p	0.010
YGL015C	hypothetical protein	0.010