IMP

Process View

Saccharomyces cerevisiae

30 genes annotated in yeast

apoptotic process

A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
HSP82	Hsp82p	0.382	Rat Worm
SLT2	Slt2p	0.220
KAR2	Kar2p	0.191	Human
STI1	Sti1p	0.135
SSA1	Ssa1p	0.109	Human Worm
RPT6	Rpt6p	0.102
RAD23	Rad23p	0.100
RPS1A	Rps1ap	0.098	Human Worm
RPL10	Rpl10p	0.091
PET9	Pet9p	0.087
CDC55	Cdc55p	0.085	Rat
HYP2	Hyp2p	0.084	Worm
PEP4	Pep4p	0.067
MUS81	Mus81p	0.062
STE11	Ste11p	0.062
HTB1	Htb1p	0.060
RPS6B	Rps6bp	0.059	Human
PBS2	Pbs2p	0.058	Worm
BFR1	Bfr1p	0.057
NOG2	Nog2p	0.056
SLA1	Sla1p	0.053
RPL5	Rpl5p	0.052
MSH2	Msh2p	0.050	Mouse Worm
CCT2	Cct2p	0.050
MCK1	Mck1p	0.048
IDH2	Idh2p	0.047
TIF5	Tif5p	0.045
ARB1	Arb1p	0.045
NOP56	Nop56p	0.044
CCT6	Cct6p	0.043	Worm
OYE2	Oye2p	0.041
BMH1	Bmh1p	0.041
MKT1	Mkt1p	0.039
RAD54	Rad54p	0.038
RPN12	Rpn12p	0.038
TIF35	Tif35p	0.038
RPL25	Rpl25p	0.037	Worm
NDE1	Nde1p	0.037
GUT2	Gut2p	0.036
ESS1	Ess1p	0.036
TSA1	Tsa1p	0.036	Rat Fly
RPN13	Rpn13p	0.036
SUB2	Sub2p	0.036
HHF1	Hhf1p	0.035
CMD1	Cmd1p	0.035
SCH9	Sch9p	0.033	Mouse Rat
YHR033W	hypothetical protein	0.033
SUP45	Sup45p	0.033
RPS5	Rps5p	0.032	Worm
RPS3	Rps3p	0.032	Human Worm Fly
SWI5	Swi5p	0.031
TRA1	Tra1p	0.031
RPT3	Rpt3p	0.030
PIL1	Pil1p	0.030
RPS7A	Rps7ap	0.029	Worm
RPL32	Rpl32p	0.029
RAD16	Rad16p	0.029
MSH3	Msh3p	0.028
ULA1	Ula1p	0.028
HER2	Her2p	0.027
RSC9	Rsc9p	0.027
RPL18A	Rpl18ap	0.027	Worm
RPL13A	Rpl13ap	0.026	Worm
PPH3	Pph3p	0.026
URA7	Ura7p	0.026	Worm
TIF6	Tif6p	0.026
DSK2	Dsk2p	0.026
ATG3	Atg3p	0.026	Mouse
PPH22	Pph22p	0.026
STM1	Stm1p	0.026
CCP1	Ccp1p	0.025
RPS1B	Rps1bp	0.025	Human Worm
ENO1	Eno1p	0.025
RPL21A	Rpl21ap	0.025	Worm
TSC11	Tsc11p	0.024
KSP1	Ksp1p	0.024
SOD2	Sod2p	0.024
KSS1	Kss1p	0.024	Worm
LAP4	Lap4p	0.024
TEF4	Tef4p	0.024
RPL19B	Rpl19bp	0.024	Worm
MYO5	Myo5p	0.023
RPL20A	Rpl20ap	0.023
UMP1	Ump1p	0.023
SEC1	Sec1p	0.023
RPN3	Rpn3p	0.023	Worm
HHT1	Hht1p	0.023
PSP2	Psp2p	0.023
RPL11A	Rpl11ap	0.023
RPL1A	Rpl1ap	0.023
RLF2	Rlf2p	0.023
MDM20	Mdm20p	0.022
ESP1	Esp1p	0.022
ALD6	Ald6p	0.022	Rat
RPL3	Rpl3p	0.022	Worm
UBP9	Ubp9p	0.022
RPL16B	Rpl16bp	0.022
MAD1	Mad1p	0.022
ATP1	Atp1p	0.022
MDV1	Mdv1p	0.022
SSA4	Ssa4p	0.021	Human Rat
PKH2	Pkh2p	0.021	Human Mouse Fly
YMR196W	hypothetical protein	0.021
RTS1	Rts1p	0.021
PUP1	Pup1p	0.021	Worm
TDH2	Tdh2p	0.021
MSN2	Msn2p	0.021
SNF5	Snf5p	0.021
NEO1	Neo1p	0.021
TEF1	Tef1p	0.021	Rat
SDP1	Sdp1p	0.021
COX15	Cox15p	0.021
LYS20	Lys20p	0.021
KEM1	Kem1p	0.021
ELP4	Elp4p	0.021
RPS11A	Rps11ap	0.021
RPL28	Rpl28p	0.020
FUN12	Fun12p	0.020
RPT1	Rpt1p	0.020
MSN1	Msn1p	0.020
MSG5	Msg5p	0.020
RPS7B	Rps7bp	0.020	Worm
CYC3	Cyc3p	0.020
RFC5	Rfc5p	0.020
SAH1	Sah1p	0.020
VMA13	Vma13p	0.020
RPL21B	Rpl21bp	0.020
GPM1	Gpm1p	0.020
ASC1	Asc1p	0.020	Human
VPS36	Vps36p	0.020
CYB2	Cyb2p	0.019
YDJ1	Ydj1p	0.019
TOR2	Tor2p	0.019
PEP3	Pep3p	0.019
YPK2	Ypk2p	0.019	Mouse Rat
RPL18B	Rpl18bp	0.019
MPT5	Mpt5p	0.019
ATG4	Atg4p	0.019
RAD53	Rad53p	0.019
PAM1	Pam1p	0.019
MLH1	Mlh1p	0.019	Mouse
PPH21	Pph21p	0.019
UBX4	Ubx4p	0.019
KAP123	Kap123p	0.019
YJR085C	hypothetical protein	0.019
BSD2	Bsd2p	0.019
ARC18	Arc18p	0.019
SIL1	Sil1p	0.019
RPL2A	Rpl2ap	0.019
YKT6	Ykt6p	0.019
RAM1	Ram1p	0.018
LHS1	Lhs1p	0.018	Human
CDC20	Cdc20p	0.018
GUS1	Gus1p	0.018
VPS29	Vps29p	0.018
CKS1	Cks1p	0.018
IQG1	Iqg1p	0.018
CDC34	Cdc34p	0.018
SPP1	Spp1p	0.018
DPL1	Dpl1p	0.018
GIS1	Gis1p	0.018
TAF11	Taf11p	0.018
GCR2	Gcr2p	0.018
PPE1	Ppe1p	0.018
RPL6A	Rpl6ap	0.018	Worm
DCS2	Dcs2p	0.018
RPS15	Rps15p	0.018	Worm
MCM4	Mcm4p	0.018
STE24	Ste24p	0.018
ACS2	Acs2p	0.018
HOG1	Hog1p	0.018	Human Mouse Rat Worm
PMT3	Pmt3p	0.018
FPK1	Fpk1p	0.018	Mouse Rat
OLA1	Ola1p	0.018
MLH2	Mlh2p	0.018
ECM29	Ecm29p	0.018
ARP2	Arp2p	0.018
PDE2	Pde2p	0.018
HOS4	Hos4p	0.018
NAT1	Nat1p	0.018	Human
SWI1	Swi1p	0.018
RPS22A	Rps22ap	0.018
DIA2	Dia2p	0.017
COQ3	Coq3p	0.017
RPG1	Rpg1p	0.017
TGL4	Tgl4p	0.017
SWP82	Swp82p	0.017
HSP78	Hsp78p	0.017
RIM11	Rim11p	0.017
ASK10	Ask10p	0.017
SGT2	Sgt2p	0.017
RNH203	Rnh203p	0.017
SCM3	Scm3p	0.017
SHE3	She3p	0.017
UNG1	Ung1p	0.017
ATG1	Atg1p	0.017
DED1	Ded1p	0.017	Human
LEM3	Lem3p	0.017
GAR1	Gar1p	0.017
LSP1	Lsp1p	0.017
RAD52	Rad52p	0.017
MBR1	Mbr1p	0.017
CCS1	Ccs1p	0.017
SAP1	Sap1p	0.017	Mouse
SMP1	Smp1p	0.016	Mouse
UBC7	Ubc7p	0.016
SKO1	Sko1p	0.016
YCK1	Yck1p	0.016
KRS1	Krs1p	0.016
PEP12	Pep12p	0.016
BEM4	Bem4p	0.016
OTU1	Otu1p	0.016
NMA111	Nma111p	0.016
SEC18	Sec18p	0.016
CMP2	Cmp2p	0.016
CCT3	Cct3p	0.016
RPS27A	Rps27ap	0.016
CLB6	Clb6p	0.016
YDL180W	hypothetical protein	0.016
LSM3	Lsm3p	0.016
SSA3	Ssa3p	0.016	Human
NTO1	Nto1p	0.016
SDA1	Sda1p	0.016
RPS6A	Rps6ap	0.016	Human Worm
RPL11B	Rpl11bp	0.016	Zebrafish
SRO7	Sro7p	0.016
VID30	Vid30p	0.016
AIM18	Aim18p	0.016
VPS45	Vps45p	0.016
YGL242C	hypothetical protein	0.015
THO2	Tho2p	0.015
SCJ1	Scj1p	0.015	Human
PGA3	Pga3p	0.015
CYT1	Cyt1p	0.015
SMF1	Smf1p	0.015	Human
SEC7	Sec7p	0.015
ATG21	Atg21p	0.015
PRE10	Pre10p	0.015
NUP157	Nup157p	0.015
ERB1	Erb1p	0.015
MSN5	Msn5p	0.015
OYE3	Oye3p	0.015
TIM54	Tim54p	0.015
HST3	Hst3p	0.015
COX4	Cox4p	0.015
UFO1	Ufo1p	0.015
SIP18	Sip18p	0.015
MRT4	Mrt4p	0.015
YNL155W	hypothetical protein	0.015
REC8	Rec8p	0.015
CSL4	Csl4p	0.015
RPL34A	Rpl34ap	0.015
RPN10	Rpn10p	0.015
PRT1	Prt1p	0.015	Worm
PLC1	Plc1p	0.015
MCM10	Mcm10p	0.015
CDC53	Cdc53p	0.015	Worm
NBP2	Nbp2p	0.015
CTI6	Cti6p	0.015
SMM1	Smm1p	0.015
MDS3	Mds3p	0.015
SUI1	Sui1p	0.015
MKS1	Mks1p	0.015
NUP49	Nup49p	0.015
NGR1	Ngr1p	0.015
MDH2	Mdh2p	0.015
RPP2B	Rpp2bp	0.014
RPP0	Rpp0p	0.014	Worm
UTP20	Utp20p	0.014
PUT4	Put4p	0.014
RAD18	Rad18p	0.014
TMA16	Tma16p	0.014
SMC3	Smc3p	0.014
PEX2	Pex2p	0.014
STE5	Ste5p	0.014
HOR7	Hor7p	0.014
GCD2	Gcd2p	0.014
BGL2	Bgl2p	0.014
KTI12	Kti12p	0.014
VID24	Vid24p	0.014
ZDS2	Zds2p	0.014
SOK1	Sok1p	0.014
AKL1	Akl1p	0.014
YLR173W	hypothetical protein	0.014
PRE8	Pre8p	0.014
TOR1	Tor1p	0.014
RPL1B	Rpl1bp	0.014
AHP1	Ahp1p	0.014
HMO1	Hmo1p	0.014
TDH1	Tdh1p	0.014	Yeast
CTF13	Ctf13p	0.014
BRO1	Bro1p	0.014
NRP1	Nrp1p	0.014
STE18	Ste18p	0.014
CAD1	Cad1p	0.014
MIR1	Mir1p	0.013
HSM3	Hsm3p	0.013
PDI1	Pdi1p	0.013
SFB2	Sfb2p	0.013
APC11	Apc11p	0.013
SSL1	Ssl1p	0.013
SRO77	Sro77p	0.013
LSM8	Lsm8p	0.013
ERR3	Err3p	0.013
HDA2	Hda2p	0.013
HOP1	Hop1p	0.013
GET3	Get3p	0.013
YDC1	Ydc1p	0.013
ECM10	Ecm10p	0.013
EFB1	Efb1p	0.013
GTT2	Gtt2p	0.013
TSR1	Tsr1p	0.013
CPR1	Cpr1p	0.013	Yeast
DNF1	Dnf1p	0.013
PAP2	Pap2p	0.013
FUS3	Fus3p	0.013	Worm
ETR1	Etr1p	0.013
YLR257W	hypothetical protein	0.013
BLM10	Blm10p	0.013
RPN5	Rpn5p	0.013
HSL1	Hsl1p	0.013
LCB2	Lcb2p	0.013
ATG13	Atg13p	0.013
STD1	Std1p	0.013
UPS3	Ups3p	0.013
POR1	Por1p	0.013
RAD4	Rad4p	0.013
NOG1	Nog1p	0.013
RPL6B	Rpl6bp	0.013	Worm
MOB1	Mob1p	0.013
ADK1	Adk1p	0.013
SAC6	Sac6p	0.013
RHO1	Rho1p	0.013	Human Mouse
CDC37	Cdc37p	0.012
JEM1	Jem1p	0.012
SCP160	Scp160p	0.012
CWC21	Cwc21p	0.012
ERO1	Ero1p	0.012
VTI1	Vti1p	0.012
CKA1	Cka1p	0.012	Human
ACH1	Ach1p	0.012
SAF1	Saf1p	0.012
DDI1	Ddi1p	0.012
HHT2	Hht2p	0.012
RPT5	Rpt5p	0.012
BYE1	Bye1p	0.012
PSA1	Psa1p	0.012
RAT1	Rat1p	0.012
NSA1	Nsa1p	0.012
ACB1	Acb1p	0.012
IRA1	Ira1p	0.012
BCK2	Bck2p	0.012
RPL36A	Rpl36ap	0.012
GAD1	Gad1p	0.012
MCH5	Mch5p	0.012
CCW12	Ccw12p	0.012
HRB1	Hrb1p	0.012
PRP9	Prp9p	0.012
YME1	Yme1p	0.012
YCL042W	hypothetical protein	0.012
TEC1	Tec1p	0.012
FZO1	Fzo1p	0.012
PEX5	Pex5p	0.012
CCT7	Cct7p	0.012	Worm
YCR061W	hypothetical protein	0.012
RPL26B	Rpl26bp	0.012
FAR11	Far11p	0.012
KDX1	Kdx1p	0.012
PRP21	Prp21p	0.012
COT1	Cot1p	0.012
HRT1	Hrt1p	0.012
KTR3	Ktr3p	0.012
PSD2	Psd2p	0.012
IKI1	Iki1p	0.012
SLK19	Slk19p	0.012
AIM14	Aim14p	0.012
CPR7	Cpr7p	0.012	Human Rat
RPA49	Rpa49p	0.012
RCK1	Rck1p	0.012	Mouse
RPS8A	Rps8ap	0.012	Worm
SAC7	Sac7p	0.012
OST2	Ost2p	0.012
MLH3	Mlh3p	0.012
SEC9	Sec9p	0.012
ORC6	Orc6p	0.012
VMA7	Vma7p	0.012
AUS1	Aus1p	0.012
CHS6	Chs6p	0.012
UBP15	Ubp15p	0.012	Rat
YFL054C	hypothetical protein	0.012
TIF34	Tif34p	0.012	Worm
AIF1	Aif1p	0.012
GET1	Get1p	0.012
NRG1	Nrg1p	0.012
LPP1	Lpp1p	0.012
CCR4	Ccr4p	0.011
MBF1	Mbf1p	0.011
RMI1	Rmi1p	0.011
SIF2	Sif2p	0.011
FPR4	Fpr4p	0.011
EMW1	Emw1p	0.011
CRR1	Crr1p	0.011
ESF2	Esf2p	0.011
ZRC1	Zrc1p	0.011
RIP1	Rip1p	0.011
SFT1	Sft1p	0.011
GPH1	Gph1p	0.011
RRP7	Rrp7p	0.011
MHT1	Mht1p	0.011
YLR162W	hypothetical protein	0.011
DCN1	Dcn1p	0.011
GGA1	Gga1p	0.011
RPC82	Rpc82p	0.011
PRR2	Prr2p	0.011
RAD3	Rad3p	0.011	Human
UTR4	Utr4p	0.011
QCR7	Qcr7p	0.011
GRE3	Gre3p	0.011
PML39	Pml39p	0.011
RPL8B	Rpl8bp	0.011
AEP3	Aep3p	0.011
SNP1	Snp1p	0.011
FMP48	Fmp48p	0.011
RPS2	Rps2p	0.011	Worm
RPL23A	Rpl23ap	0.011
SUM1	Sum1p	0.011
DEF1	Def1p	0.011
MEC1	Mec1p	0.011
AZF1	Azf1p	0.011
DOA1	Doa1p	0.011
SOD1	Sod1p	0.011	Mouse
DCW1	Dcw1p	0.011
SBA1	Sba1p	0.011
SED5	Sed5p	0.011
ATG16	Atg16p	0.011
GSP2	Gsp2p	0.011
MKK1	Mkk1p	0.011
RLI1	Rli1p	0.011	Fly
HEM12	Hem12p	0.011
WTM2	Wtm2p	0.011
XKS1	Xks1p	0.011
SGE1	Sge1p	0.011
CKA2	Cka2p	0.011	Human
HSC82	Hsc82p	0.011	Worm
MON2	Mon2p	0.011
YML053C	hypothetical protein	0.011
BDH2	Bdh2p	0.011
RED1	Red1p	0.011
RPS31	Rps31p	0.011
KIN3	Kin3p	0.011
RDL1	Rdl1p	0.011
PKC1	Pkc1p	0.011	Human Zebrafish Mouse Rat Fly
URA6	Ura6p	0.011
CTF8	Ctf8p	0.011
FMN1	Fmn1p	0.011
PHM7	Phm7p	0.011
OSH3	Osh3p	0.011
PFS1	Pfs1p	0.011
EXG2	Exg2p	0.011
RPL12B	Rpl12bp	0.011	Worm
SRP68	Srp68p	0.011
POL3	Pol3p	0.011
SKP1	Skp1p	0.011	Worm
CCT8	Cct8p	0.011
RNR2	Rnr2p	0.011
SMA1	Sma1p	0.011
IMD3	Imd3p	0.011
MDM34	Mdm34p	0.011
BUB3	Bub3p	0.011
SSN8	Ssn8p	0.010
RFX1	Rfx1p	0.010
RPT4	Rpt4p	0.010
AEP1	Aep1p	0.010
SRP54	Srp54p	0.010
ROD1	Rod1p	0.010
CLB3	Clb3p	0.010
NPT1	Npt1p	0.010
RPL2B	Rpl2bp	0.010
SQT1	Sqt1p	0.010
NDC1	Ndc1p	0.010
MTC4	Mtc4p	0.010
YBR235W	hypothetical protein	0.010
UBP1	Ubp1p	0.010
TAL1	Tal1p	0.010
SPE3	Spe3p	0.010
PFS2	Pfs2p	0.010
RPL27B	Rpl27bp	0.010
RAD59	Rad59p	0.010
YAP6	Yap6p	0.010
AQR1	Aqr1p	0.010
SMC6	Smc6p	0.010
PRM7	Prm7p	0.010
RPS19B	Rps19bp	0.010
YSA1	Ysa1p	0.010
PHO23	Pho23p	0.010	Mouse
MPC54	Mpc54p	0.010
KIN1	Kin1p	0.010
HAS1	Has1p	0.010
STV1	Stv1p	0.010
URA2	Ura2p	0.010
ANB1	Anb1p	0.010	Mouse
CAT8	Cat8p	0.010
YPL113C	hypothetical protein	0.010
VPS64	Vps64p	0.010
TCP1	Tcp1p	0.010	Mouse Worm
ADP1	Adp1p	0.010
RPP1B	Rpp1bp	0.010
YNL115C	hypothetical protein	0.010
MAD3	Mad3p	0.010
NPC2	Npc2p	0.010
TFC3	Tfc3p	0.010
FCF1	Fcf1p	0.010
YOR052C	hypothetical protein	0.010
GCN4	Gcn4p	0.010
GAL7	Gal7p	0.010
UBA1	Uba1p	0.010
YAK1	Yak1p	0.010
SMD2	Smd2p	0.010
PUP3	Pup3p	0.010
FUN30	Fun30p	0.010
RPL26A	Rpl26ap	0.010