IMP

Process View

Saccharomyces cerevisiae

14 genes annotated in yeast

srp dependent cotranslational protein targeting to membrane

The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "srp dependent cotranslational protein targeting to membrane"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "srp dependent cotranslational protein targeting to membrane" (in gray)

Name	Description	Probability
SEC63	Sec63p	0.998
KAR2	Kar2p	0.998
SBH1	Sbh1p	0.575
SRP54	Srp54p	0.554
SRP14	Srp14p	0.547
JEM1	Jem1p	0.540
SRP21	Srp21p	0.536
SEC62	Sec62p	0.499
SSS1	Sss1p	0.437
SSA2	Ssa2p	0.436
SSA4	Ssa4p	0.377
OST4	Ost4p	0.330
SSA3	Ssa3p	0.309
PMT1	Pmt1p	0.292
SIL1	Sil1p	0.261
ERO1	Ero1p	0.257
SRP72	Srp72p	0.216
WBP1	Wbp1p	0.198
STI1	Sti1p	0.198
SSA1	Ssa1p	0.071
SCJ1	Scj1p	0.067
SIS1	Sis1p	0.061
SRP68	Srp68p	0.059
RPS29B	Rps29bp	0.044
YLR264C-A	hypothetical protein	0.040
CUP1-1	Cup1-1p	0.036
MPD1	Mpd1p	0.034
SRD1	Srd1p	0.032
LEU2	Leu2p	0.031
SUB2	Sub2p	0.031
BTN2	Btn2p	0.030
SSE1	Sse1p	0.029
TDH1	Tdh1p	0.028
NMT1	Nmt1p	0.027
PRS2	Prs2p	0.026
YHB1	Yhb1p	0.025
SAR1	Sar1p	0.024
YOL038C-A	hypothetical protein	0.024
YLR162W	hypothetical protein	0.023
ARP10	Arp10p	0.022
MER1	Mer1p	0.022
ENO1	Eno1p	0.021
URA3	Ura3p	0.021
GYL1	Gyl1p	0.020
YLR042C	hypothetical protein	0.020
YSY6	Ysy6p	0.020
NOP10	Nop10p	0.019
CRP1	Crp1p	0.019
YIR035C	hypothetical protein	0.019
HO	Hop	0.018
YLR126C	hypothetical protein	0.018
SPL2	Spl2p	0.018
RPL15B	Rpl15bp	0.018
HXT3	Hxt3p	0.018
YDL085C-A	hypothetical protein	0.018
TYE7	Tye7p	0.017
YAR068W	hypothetical protein	0.017
SFB2	Sfb2p	0.017
RPL41A	Rpl41ap	0.017
GLN1	Gln1p	0.017
YPR157W	hypothetical protein	0.017
YOL013W-A	hypothetical protein	0.017
ZPS1	Zps1p	0.017
TSC3	Tsc3p	0.016
YMR130W	hypothetical protein	0.016
OYE2	Oye2p	0.016
ATP6	Atp6p	0.016
YBR013C	hypothetical protein	0.016
ARG8	Arg8p	0.016
SES1	Ses1p	0.015
SEC66	Sec66p	0.015
MF(ALPHA)2	Mf(alpha)2p	0.015
BSC1	Bsc1p	0.015
AUA1	Aua1p	0.015
ICS2	Ics2p	0.014
ALG12	Alg12p	0.014
TAD2	Tad2p	0.014
MCD4	Mcd4p	0.014
SWC7	Swc7p	0.014
CPD1	Cpd1p	0.014
HPF1	Hpf1p	0.014
SEC20	Sec20p	0.014
ALT2	Alt2p	0.014
TEF1	Tef1p	0.014
OPT2	Opt2p	0.013
YKR075C	hypothetical protein	0.013
PTR2	Ptr2p	0.013
YRB1	Yrb1p	0.012
FMT1	Fmt1p	0.012
REX2	Rex2p	0.012
DIC1	Dic1p	0.012
SRX1	Srx1p	0.012
ADH2	Adh2p	0.012
GTT2	Gtt2p	0.012
FAS2	Fas2p	0.011
CCT8	Cct8p	0.011
YLR040C	hypothetical protein	0.011
CUP1-2	Cup1-2p	0.011
CHA1	Cha1p	0.011
YMR122W-A	hypothetical protein	0.011
YGR126W	hypothetical protein	0.011
SEC26	Sec26p	0.011
UPS3	Ups3p	0.011
SFB3	Sfb3p	0.011
SCM4	Scm4p	0.011
ILS1	Ils1p	0.011
NRG2	Nrg2p	0.011
HLJ1	Hlj1p	0.011
YML003W	hypothetical protein	0.011
YJL107C	hypothetical protein	0.011
VMA4	Vma4p	0.011
ERD2	Erd2p	0.011
LCL2	Lcl2p	0.010
YAL037C-A	hypothetical protein	0.010
YPR096C	hypothetical protein	0.010
RNP1	Rnp1p	0.010
YPL067C	hypothetical protein	0.010
COS12	Cos12p	0.010
DIF1	Dif1p	0.010
SEC1	Sec1p	0.010
LRO1	Lro1p	0.010
YAL064W	hypothetical protein	0.010
GPX2	Gpx2p	0.010
IMD3	Imd3p	0.010
YCH1	Ych1p	0.010