IMP

Process View

Saccharomyces cerevisiae

34 genes annotated in yeast

mitotic spindle checkpoint

A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitotic spindle checkpoint"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitotic spindle checkpoint" (in gray)

Name	Description	Probability	Func Analog Organism
PPH21	Pph21p	0.932
KEL1	Kel1p	0.884
CDC28	Cdc28p	0.826
PPH22	Pph22p	0.816
GLC7	Glc7p	0.771
SLK19	Slk19p	0.753
CDC20	Cdc20p	0.735
BUB3	Bub3p	0.677	Worm Fly
BFA1	Bfa1p	0.631
BUB1	Bub1p	0.617
MAD2	Mad2p	0.580
CLB4	Clb4p	0.574	Human
GIC1	Gic1p	0.564
NUD1	Nud1p	0.548
RTS1	Rts1p	0.540
MAD3	Mad3p	0.500
MCM21	Mcm21p	0.498
CDC5	Cdc5p	0.388	Human
CDC55	Cdc55p	0.387
FMP48	Fmp48p	0.365
SLI15	Sli15p	0.358
HHT1	Hht1p	0.344	Yeast
PPZ1	Ppz1p	0.302
HHF2	Hhf2p	0.292
IML3	Iml3p	0.266
MPS1	Mps1p	0.264
CTF13	Ctf13p	0.254
ELM1	Elm1p	0.239
CAB3	Cab3p	0.217
KIP1	Kip1p	0.208
PIG2	Pig2p	0.208	Yeast
BUB2	Bub2p	0.206
YPI1	Ypi1p	0.203
BMH1	Bmh1p	0.196
REG1	Reg1p	0.195
PCL10	Pcl10p	0.182
CKA1	Cka1p	0.181	Human
CLB3	Clb3p	0.172	Human
CDC14	Cdc14p	0.160
CTF3	Ctf3p	0.148
GIP2	Gip2p	0.145	Yeast
CLB1	Clb1p	0.140
KIC1	Kic1p	0.138
SIC1	Sic1p	0.137
SFI1	Sfi1p	0.135
SGO1	Sgo1p	0.125
SPC24	Spc24p	0.121
ASE1	Ase1p	0.120
BMH2	Bmh2p	0.118	Yeast
SKP2	Skp2p	0.117
TOF2	Tof2p	0.110
DMA2	Dma2p	0.108
KCS1	Kcs1p	0.107
TPD3	Tpd3p	0.105
FAR1	Far1p	0.101
BIM1	Bim1p	0.100
ORC3	Orc3p	0.098
DMA1	Dma1p	0.094
CLB6	Clb6p	0.093
MAD1	Mad1p	0.091
SDS22	Sds22p	0.090
GAC1	Gac1p	0.084
BUD8	Bud8p	0.083
VIK1	Vik1p	0.083
NBL1	Nbl1p	0.080
AME1	Ame1p	0.074
TGL2	Tgl2p	0.070
CDH1	Cdh1p	0.069
KEL2	Kel2p	0.068
STE23	Ste23p	0.068
CBF1	Cbf1p	0.063
CIN1	Cin1p	0.063
CIN8	Cin8p	0.062
NDD1	Ndd1p	0.062
KIN1	Kin1p	0.060
SKM1	Skm1p	0.060
CDC123	Cdc123p	0.059
MSA2	Msa2p	0.057
ESP1	Esp1p	0.056
LTE1	Lte1p	0.054
HST3	Hst3p	0.053
ZDS1	Zds1p	0.052
SPC29	Spc29p	0.045
ECO1	Eco1p	0.043
YIL151C	hypothetical protein	0.043
NTO1	Nto1p	0.042
DAM1	Dam1p	0.042
FRK1	Frk1p	0.042
STE4	Ste4p	0.041
SOL1	Sol1p	0.041
RAD53	Rad53p	0.041
CHL4	Chl4p	0.040
GLG1	Glg1p	0.039
SPC110	Spc110p	0.039
SRD1	Srd1p	0.039
FIN1	Fin1p	0.038
CKB1	Ckb1p	0.038
CAR1	Car1p	0.037
DSN1	Dsn1p	0.036
PSY4	Psy4p	0.036
VHS2	Vhs2p	0.036
WHI5	Whi5p	0.035
TIP41	Tip41p	0.035
KAR9	Kar9p	0.035
HHT2	Hht2p	0.035
YLR264C-A	hypothetical protein	0.034
MIF2	Mif2p	0.033
YLR162W	hypothetical protein	0.033
YKL075C	hypothetical protein	0.033
CKS1	Cks1p	0.033
PSK1	Psk1p	0.033
YOL038C-A	hypothetical protein	0.032
CDC16	Cdc16p	0.031
YNR014W	hypothetical protein	0.030
ARP10	Arp10p	0.030
MER1	Mer1p	0.030
PDS1	Pds1p	0.030
PKH3	Pkh3p	0.030
CKB2	Ckb2p	0.030
YBP1	Ybp1p	0.030
NSL1	Nsl1p	0.029
CUP1-1	Cup1-1p	0.029
LEU2	Leu2p	0.029
RAD54	Rad54p	0.029
VAC17	Vac17p	0.028
ZPS1	Zps1p	0.027
CPD1	Cpd1p	0.026
HSL1	Hsl1p	0.026
BCK2	Bck2p	0.026
SWE1	Swe1p	0.025
SPC97	Spc97p	0.025
ARG8	Arg8p	0.025
MBP1	Mbp1p	0.025
SPC42	Spc42p	0.025
SPS4	Sps4p	0.025
NUP53	Nup53p	0.025
OSH3	Osh3p	0.024
SET4	Set4p	0.024
KIP2	Kip2p	0.024
RIO1	Rio1p	0.024
CDC7	Cdc7p	0.024
BUD5	Bud5p	0.024
CDC15	Cdc15p	0.024
RTS2	Rts2p	0.024
GIP3	Gip3p	0.024
YLR419W	hypothetical protein	0.024
SGV1	Sgv1p	0.024
YNL234W	hypothetical protein	0.024
NUP157	Nup157p	0.024
SPL2	Spl2p	0.024
PRS2	Prs2p	0.023
YAR068W	hypothetical protein	0.023
VHS3	Vhs3p	0.023
ATP6	Atp6p	0.023
CRP1	Crp1p	0.023
SGM1	Sgm1p	0.023
ICS2	Ics2p	0.023
WSS1	Wss1p	0.023
YPL068C	hypothetical protein	0.023
CNM67	Cnm67p	0.023
NCE103	Nce103p	0.023
CDC6	Cdc6p	0.023
URA3	Ura3p	0.023
DBF20	Dbf20p	0.023
HPF1	Hpf1p	0.023
YLR407W	hypothetical protein	0.023
PUF2	Puf2p	0.022
YBR013C	hypothetical protein	0.022
RED1	Red1p	0.022
TAH11	Tah11p	0.022
MTW1	Mtw1p	0.022
BIT61	Bit61p	0.022
PMA2	Pma2p	0.022
MRK1	Mrk1p	0.022
YGL010W	hypothetical protein	0.022
YNL144C	hypothetical protein	0.022
PTI1	Pti1p	0.022
AAD15	Aad15p	0.022
YPL216W	hypothetical protein	0.022
AAD6	Aad6p	0.021
DIF1	Dif1p	0.021
AUA1	Aua1p	0.021
ADH2	Adh2p	0.021
RRN6	Rrn6p	0.021
YPR157W	hypothetical protein	0.021
LIF1	Lif1p	0.021
HRR25	Hrr25p	0.021
HXT3	Hxt3p	0.021
YLR042C	hypothetical protein	0.021
TAF7	Taf7p	0.021
TEM1	Tem1p	0.021
SLD3	Sld3p	0.021
CSM1	Csm1p	0.021
TYE7	Tye7p	0.020
CDC25	Cdc25p	0.020
SWI6	Swi6p	0.020
YOL013W-A	hypothetical protein	0.020
SPC98	Spc98p	0.020
NUF2	Nuf2p	0.019
PCT1	Pct1p	0.019
THP3	Thp3p	0.019
ALT2	Alt2p	0.019
YML053C	hypothetical protein	0.019
SUR1	Sur1p	0.019
UBR2	Ubr2p	0.019
RAD61	Rad61p	0.019
YOR059C	hypothetical protein	0.018
SYN8	Syn8p	0.018
UPS3	Ups3p	0.018
CHK1	Chk1p	0.018
PPR1	Ppr1p	0.018
MF(ALPHA)2	Mf(alpha)2p	0.018
YPR117W	hypothetical protein	0.018
YKR075C	hypothetical protein	0.018
FMT1	Fmt1p	0.018
YPR096C	hypothetical protein	0.018
CDC4	Cdc4p	0.018
SLG1	Slg1p	0.018
OPT2	Opt2p	0.018
YAL037C-A	hypothetical protein	0.018
YML003W	hypothetical protein	0.018
PIK1	Pik1p	0.018
YAR066W	hypothetical protein	0.018
TAM41	Tam41p	0.017
POG1	Pog1p	0.017
LCL1	Lcl1p	0.017
AZF1	Azf1p	0.017
INP2	Inp2p	0.017
AQR1	Aqr1p	0.017
PRM4	Prm4p	0.017
ARE2	Are2p	0.017
PRM3	Prm3p	0.017
BRE2	Bre2p	0.017
YIR035C	hypothetical protein	0.017
FPK1	Fpk1p	0.017
YLR040C	hypothetical protein	0.017
YJL181W	hypothetical protein	0.017
YGR035C	hypothetical protein	0.017
REH1	Reh1p	0.017
YAL064W	hypothetical protein	0.017
BSC1	Bsc1p	0.017
RNP1	Rnp1p	0.016
BNA4	Bna4p	0.016
CSE4	Cse4p	0.016
IZH4	Izh4p	0.016
DIC1	Dic1p	0.016
MMS1	Mms1p	0.016
PHM6	Phm6p	0.016
YBL029W	hypothetical protein	0.016
EEB1	Eeb1p	0.016
SNF11	Snf11p	0.016
JHD2	Jhd2p	0.016
PSP1	Psp1p	0.016
SKP1	Skp1p	0.016
YCH1	Ych1p	0.016
ARR2	Arr2p	0.016
TPM2	Tpm2p	0.016
SSY5	Ssy5p	0.016
BOP3	Bop3p	0.016
QNS1	Qns1p	0.016
TOR2	Tor2p	0.016
AAT1	Aat1p	0.016
YGL006W-A	hypothetical protein	0.016
SPO74	Spo74p	0.016
IRC8	Irc8p	0.016
YKR045C	hypothetical protein	0.016
SPC105	Spc105p	0.016
CRN1	Crn1p	0.015
YHR035W	hypothetical protein	0.015
MFA2	Mfa2p	0.015
YPL014W	hypothetical protein	0.015
PTR2	Ptr2p	0.015
HOR2	Hor2p	0.015
YJR056C	hypothetical protein	0.015
YNL033W	hypothetical protein	0.015
YJL107C	hypothetical protein	0.015
YNR063W	hypothetical protein	0.015
BIO2	Bio2p	0.015
JLP2	Jlp2p	0.015
BDF2	Bdf2p	0.015
FCY22	Fcy22p	0.015
YMR317W	hypothetical protein	0.015
SCM4	Scm4p	0.015
YNR062C	hypothetical protein	0.015
PAC2	Pac2p	0.015
NSE5	Nse5p	0.015
YNL067W-B	hypothetical protein	0.015
TIR3	Tir3p	0.015
YEA6	Yea6p	0.015
YCR050C	hypothetical protein	0.015
PKC1	Pkc1p	0.015
MDJ2	Mdj2p	0.015
ENA5	Ena5p	0.015
PDC5	Pdc5p	0.015
IKI1	Iki1p	0.015
YJL160C	hypothetical protein	0.014
IDS2	Ids2p	0.014
YPR153W	hypothetical protein	0.014
SNF3	Snf3p	0.014
YLR281C	hypothetical protein	0.014
KRE29	Kre29p	0.014
NGL2	Ngl2p	0.014
YJR098C	hypothetical protein	0.014
SPO14	Spo14p	0.014
YGK3	Ygk3p	0.014
YDR034C-A	hypothetical protein	0.014
EST2	Est2p	0.014
YNL058C	hypothetical protein	0.014
YJR120W	hypothetical protein	0.014
AIF1	Aif1p	0.014
YPL067C	hypothetical protein	0.014
NRG2	Nrg2p	0.014
MF(ALPHA)1	Mf(alpha)1p	0.014
SPO12	Spo12p	0.014
DUR1,2	Dur1,2p	0.014
MEC1	Mec1p	0.014
PCD1	Pcd1p	0.014
RRN5	Rrn5p	0.014
YOL014W	hypothetical protein	0.014
MDM20	Mdm20p	0.014
YLR445W	hypothetical protein	0.014
VBA5	Vba5p	0.014
YDL186W	hypothetical protein	0.014
YLR278C	hypothetical protein	0.014
BDS1	Bds1p	0.014
MET8	Met8p	0.014
YKL070W	hypothetical protein	0.013
UBC4	Ubc4p	0.013
REV1	Rev1p	0.013
PRP28	Prp28p	0.013
RDH54	Rdh54p	0.013
SWI1	Swi1p	0.013
MPH1	Mph1p	0.013
RMD6	Rmd6p	0.013
RRP36	Rrp36p	0.013
HIT1	Hit1p	0.013
YGR017W	hypothetical protein	0.013
YOR387C	hypothetical protein	0.013
SMC4	Smc4p	0.013
KIN3	Kin3p	0.013
YNL162W-A	hypothetical protein	0.013
YDR222W	hypothetical protein	0.013
LYS14	Lys14p	0.013
CAB2	Cab2p	0.013
YNL018C	hypothetical protein	0.013
CTS1	Cts1p	0.013
NDL1	Ndl1p	0.013
YGL036W	hypothetical protein	0.013
RTT105	Rtt105p	0.013
GSH1	Gsh1p	0.013
FYV10	Fyv10p	0.013
YMR1	Ymr1p	0.013
DAL7	Dal7p	0.013
PDC6	Pdc6p	0.013
COS12	Cos12p	0.013
SOR2	Sor2p	0.013
SAG1	Sag1p	0.013
CHA1	Cha1p	0.013
YPL168W	hypothetical protein	0.013
AQY2	Aqy2p	0.013
YJL218W	hypothetical protein	0.013
HMLALPHA2	Hmlalpha2p	0.013
RRT5	Rrt5p	0.013
YAR028W	hypothetical protein	0.013
KNH1	Knh1p	0.013
AHP1	Ahp1p	0.013
IST1	Ist1p	0.013
PSP2	Psp2p	0.013
YCL001W-B	hypothetical protein	0.013
YAR029W	hypothetical protein	0.012
LUC7	Luc7p	0.012
YPR027C	hypothetical protein	0.012
HMRA1	Hmra1p	0.012
YOR060C	hypothetical protein	0.012
YLR049C	hypothetical protein	0.012
SEO1	Seo1p	0.012
SIT1	Sit1p	0.012
SUT1	Sut1p	0.012
MMS22	Mms22p	0.012
YGL235W	hypothetical protein	0.012
YMR122W-A	hypothetical protein	0.012
IPL1	Ipl1p	0.012
EDC1	Edc1p	0.012
YOR012W	hypothetical protein	0.012
HUG1	Hug1p	0.012
ICS3	Ics3p	0.012
YCR102C	hypothetical protein	0.012
BIO5	Bio5p	0.012
YPR159C-A	hypothetical protein	0.012
GYP8	Gyp8p	0.012
YKR041W	hypothetical protein	0.012
SRX1	Srx1p	0.012
MIH1	Mih1p	0.012
IME4	Ime4p	0.012
ISR1	Isr1p	0.012
YFR057W	hypothetical protein	0.012
YLR412C-A	hypothetical protein	0.012
YER186C	hypothetical protein	0.012
REE1	Ree1p	0.012
TEL1	Tel1p	0.012
KAP120	Kap120p	0.012
YNL034W	hypothetical protein	0.012
RTC5	Rtc5p	0.012
SRT1	Srt1p	0.012
BET4	Bet4p	0.012
ARO10	Aro10p	0.012
YGL015C	hypothetical protein	0.012
MMP1	Mmp1p	0.012
YIR042C	hypothetical protein	0.012
CDC37	Cdc37p	0.012
YKL106C-A	hypothetical protein	0.012
YML100W-A	hypothetical protein	0.012
SAM3	Sam3p	0.012
ARF3	Arf3p	0.012
SGE1	Sge1p	0.012
MLC1	Mlc1p	0.012
CFD1	Cfd1p	0.012
TIP1	Tip1p	0.012
CMK1	Cmk1p	0.012
YAL018C	hypothetical protein	0.012
STB2	Stb2p	0.012
TRI1	Tri1p	0.012
FRE5	Fre5p	0.012
VEL1	Vel1p	0.012
TIS11	Tis11p	0.012
HMS1	Hms1p	0.011
BI4	Bi4p	0.011
DOG1	Dog1p	0.011
TSC3	Tsc3p	0.011
OYE3	Oye3p	0.011
YIL002W-A	hypothetical protein	0.011
SRO77	Sro77p	0.011
SLI1	Sli1p	0.011
SHE1	She1p	0.011
RHO1	Rho1p	0.011
RPI1	Rpi1p	0.011
SEN54	Sen54p	0.011
SIS2	Sis2p	0.011
HO	Hop	0.011
UBR1	Ubr1p	0.011
YPL113C	hypothetical protein	0.011
YER085C	hypothetical protein	0.011
PCL5	Pcl5p	0.011
YLR342W-A	hypothetical protein	0.011
GIP1	Gip1p	0.011
HTA1	Hta1p	0.011
YDR444W	hypothetical protein	0.011
YER175W-A	hypothetical protein	0.011
MNE1	Mne1p	0.011
IMA5	Ima5p	0.011
NEO1	Neo1p	0.011
YLR012C	hypothetical protein	0.011
TFG1	Tfg1p	0.011
YKL068W-A	hypothetical protein	0.011
YSC83	Ysc83p	0.011
ATO3	Ato3p	0.011
YDL129W	hypothetical protein	0.011
SPO22	Spo22p	0.011
PAM1	Pam1p	0.011
HXT2	Hxt2p	0.011
KTR4	Ktr4p	0.011
BOR1	Bor1p	0.011
YIL089W	hypothetical protein	0.011
SPH1	Sph1p	0.011
MKS1	Mks1p	0.011
YLR046C	hypothetical protein	0.011
YGL262W	hypothetical protein	0.011
FIT2	Fit2p	0.011
SET5	Set5p	0.011
PHO11	Pho11p	0.011
YKR011C	hypothetical protein	0.011
CBP1	Cbp1p	0.011
DCR2	Dcr2p	0.011
LCB4	Lcb4p	0.011
YNL190W	hypothetical protein	0.011
PIR1	Pir1p	0.011
YCF1	Ycf1p	0.011
SNA2	Sna2p	0.011
YDR524W-C	hypothetical protein	0.011
HUR1	Hur1p	0.011
YHR177W	hypothetical protein	0.011
YDR182W-A	hypothetical protein	0.011
KTR5	Ktr5p	0.011
UGA4	Uga4p	0.011
ECM3	Ecm3p	0.011
YDR042C	hypothetical protein	0.010
YGR126W	hypothetical protein	0.010
YBL044W	hypothetical protein	0.010
IOC2	Ioc2p	0.010
ZRT1	Zrt1p	0.010
NUP42	Nup42p	0.010
YLL053C	hypothetical protein	0.010
YPL277C	hypothetical protein	0.010
CCT2	Cct2p	0.010
YAT1	Yat1p	0.010
CTR3	Ctr3p	0.010
AMA1	Ama1p	0.010
ATR1	Atr1p	0.010
CAB4	Cab4p	0.010
MDM36	Mdm36p	0.010
RNR3	Rnr3p	0.010
DAK2	Dak2p	0.010
YOL086W-A	hypothetical protein	0.010
YOR022C	hypothetical protein	0.010
FAR11	Far11p	0.010
DBF4	Dbf4p	0.010
ENB1	Enb1p	0.010
RAD24	Rad24p	0.010
SWI4	Swi4p	0.010
YLR460C	hypothetical protein	0.010
CHL1	Chl1p	0.010
FRE4	Fre4p	0.010
YPL066W	hypothetical protein	0.010
WSC4	Wsc4p	0.010
YML119W	hypothetical protein	0.010
YOR316C-A	hypothetical protein	0.010
YNL097C-B	hypothetical protein	0.010
MUM3	Mum3p	0.010
YMR001C-A	hypothetical protein	0.010