IMP

Process View

Saccharomyces cerevisiae

15 genes annotated in yeast

nuclear transcribed mrna catabolic process nonsense mediated decay

The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nuclear transcribed mrna catabolic process nonsense mediated decay"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nuclear transcribed mrna catabolic process nonsense mediated decay" (in gray)

Name	Description	Probability	Func Analog Organism
TIF4632	Tif4632p	0.769
TIF4631	Tif4631p	0.761
SKI2	Ski2p	0.525
SKI3	Ski3p	0.313
DED1	Ded1p	0.222
DCP2	Dcp2p	0.210	Human
CSL4	Csl4p	0.166
GBP2	Gbp2p	0.150
SKI8	Ski8p	0.109
SKI7	Ski7p	0.098
URB2	Urb2p	0.048
MTR3	Mtr3p	0.046
TIF1	Tif1p	0.044
LRP1	Lrp1p	0.043
NAM7	Nam7p	0.041
RRP45	Rrp45p	0.038
NMD2	Nmd2p	0.034
NPL3	Npl3p	0.033
DEG1	Deg1p	0.031
RRP6	Rrp6p	0.030	Human
NOP12	Nop12p	0.029
HOS2	Hos2p	0.028
DHH1	Dhh1p	0.027
NOP10	Nop10p	0.026
PRP42	Prp42p	0.025
SNU56	Snu56p	0.024
SAD1	Sad1p	0.023
YLR264C-A	hypothetical protein	0.022
GLN1	Gln1p	0.022
ENT5	Ent5p	0.021
UBP1	Ubp1p	0.020
CBC2	Cbc2p	0.020	Human
ARG8	Arg8p	0.020
PUB1	Pub1p	0.020
SRD1	Srd1p	0.020
KEM1	Kem1p	0.020
LUC7	Luc7p	0.020
RRP46	Rrp46p	0.020
HRP1	Hrp1p	0.019
EDC3	Edc3p	0.019
URA3	Ura3p	0.019
MER1	Mer1p	0.018
ESF1	Esf1p	0.017
ISR1	Isr1p	0.017
YLR162W	hypothetical protein	0.017
LEU2	Leu2p	0.017
YOL038C-A	hypothetical protein	0.017
TGS1	Tgs1p	0.017
PRP11	Prp11p	0.017
HST1	Hst1p	0.017
PRS2	Prs2p	0.016
SPL2	Spl2p	0.016
YBR016W	hypothetical protein	0.016
ARP10	Arp10p	0.015
TAE2	Tae2p	0.015
NUP49	Nup49p	0.015
PRP28	Prp28p	0.014
YTA6	Yta6p	0.014
YAR068W	hypothetical protein	0.014
SWM2	Swm2p	0.014
CUP1-1	Cup1-1p	0.014
HXT3	Hxt3p	0.014
YPR157W	hypothetical protein	0.013
HPF1	Hpf1p	0.013
GDS1	Gds1p	0.013
AQR1	Aqr1p	0.013
ATP6	Atp6p	0.013
SUP35	Sup35p	0.013
CRP1	Crp1p	0.013
NUP157	Nup157p	0.013
YLR042C	hypothetical protein	0.013
ZPS1	Zps1p	0.013
YBT1	Ybt1p	0.013
ICS2	Ics2p	0.013
AUA1	Aua1p	0.012
CPD1	Cpd1p	0.012
YIR035C	hypothetical protein	0.012
NRD1	Nrd1p	0.012
EXO70	Exo70p	0.012
YBR013C	hypothetical protein	0.012
MF(ALPHA)2	Mf(alpha)2p	0.012
PAB1	Pab1p	0.012	Human
YOL013W-A	hypothetical protein	0.012
OPT2	Opt2p	0.012
ADY2	Ady2p	0.012
MEX67	Mex67p	0.012
SWC7	Swc7p	0.012
AIR1	Air1p	0.012
AIR2	Air2p	0.011
PUT4	Put4p	0.011
UPS3	Ups3p	0.011
FMT1	Fmt1p	0.011
YHB1	Yhb1p	0.011
YOL014W	hypothetical protein	0.011
BTT1	Btt1p	0.011
YIL151C	hypothetical protein	0.011
YLR363W-A	hypothetical protein	0.011
REE1	Ree1p	0.011
CHA1	Cha1p	0.011
PFK27	Pfk27p	0.011
PHM6	Phm6p	0.011
YRA2	Yra2p	0.011
LOS1	Los1p	0.011
GPD2	Gpd2p	0.011
NUP60	Nup60p	0.011
YPR096C	hypothetical protein	0.011
RNA14	Rna14p	0.011
TSC3	Tsc3p	0.011
TYE7	Tye7p	0.011
SUT2	Sut2p	0.011
HO	Hop	0.011
RPA135	Rpa135p	0.011
NAN1	Nan1p	0.011
FUN12	Fun12p	0.011
STO1	Sto1p	0.010
ARO10	Aro10p	0.010
YLR040C	hypothetical protein	0.010
YJL107C	hypothetical protein	0.010
SEN54	Sen54p	0.010
ARE2	Are2p	0.010
SEC65	Sec65p	0.010
YLL054C	hypothetical protein	0.010
YKR075C	hypothetical protein	0.010
AQY2	Aqy2p	0.010
YOR012W	hypothetical protein	0.010
SRP68	Srp68p	0.010
SCM4	Scm4p	0.010
MAK10	Mak10p	0.010
RSN1	Rsn1p	0.010