IMP

Process View

Saccharomyces cerevisiae

33 genes annotated in yeast

negative regulation of proteolysis

Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in yeast Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of proteolysis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of proteolysis" (in gray)

Name	Description	Probability	Func Analog Organism
CDC55	Cdc55p	0.976
PPH21	Pph21p	0.910
GLC7	Glc7p	0.880
PPH22	Pph22p	0.744
MAD2	Mad2p	0.481
RTS1	Rts1p	0.424
CDC20	Cdc20p	0.385
YPI1	Ypi1p	0.320
CTF13	Ctf13p	0.288
MAD3	Mad3p	0.256
CSE4	Cse4p	0.247
CTF3	Ctf3p	0.217
GIP2	Gip2p	0.213	Yeast
PIG2	Pig2p	0.210	Yeast
PSP2	Psp2p	0.207
STI1	Sti1p	0.195
SLK19	Slk19p	0.188
KIP1	Kip1p	0.187
MLC1	Mlc1p	0.185
PHB1	Phb1p	0.177
IML3	Iml3p	0.147
CKB1	Ckb1p	0.146
ASE1	Ase1p	0.144
CHL4	Chl4p	0.120
KIC1	Kic1p	0.116
HTA1	Hta1p	0.113
BUB3	Bub3p	0.099	Worm Fly
MCM21	Mcm21p	0.093
RHO1	Rho1p	0.080
PAN1	Pan1p	0.079
CBF2	Cbf2p	0.078
TIP41	Tip41p	0.076
TPD3	Tpd3p	0.075
NOG1	Nog1p	0.075
RPT2	Rpt2p	0.070
TAF5	Taf5p	0.067
MIA40	Mia40p	0.067
BMH1	Bmh1p	0.067	Human
YBP2	Ybp2p	0.061
PSH1	Psh1p	0.061
GAC1	Gac1p	0.060
MIF2	Mif2p	0.059
YKL075C	hypothetical protein	0.058
PHB2	Phb2p	0.057
BCK1	Bck1p	0.057
BMH2	Bmh2p	0.057	Human
STU1	Stu1p	0.056
OKP1	Okp1p	0.056
ECO1	Eco1p	0.056
CMK1	Cmk1p	0.055
APM2	Apm2p	0.053
SAP155	Sap155p	0.053
WWM1	Wwm1p	0.052
CKB2	Ckb2p	0.051
SUS1	Sus1p	0.049
CIN8	Cin8p	0.049
SSA3	Ssa3p	0.048
PCL10	Pcl10p	0.047
CDC24	Cdc24p	0.047
MCM22	Mcm22p	0.047
RAD23	Rad23p	0.045
FMP48	Fmp48p	0.045
PSY4	Psy4p	0.045
SDS22	Sds22p	0.043
NSL1	Nsl1p	0.043
TOR2	Tor2p	0.043
TAF10	Taf10p	0.043
YTA12	Yta12p	0.042
SAP4	Sap4p	0.041
TAF6	Taf6p	0.038
MPH1	Mph1p	0.038
PIM1	Pim1p	0.038
BTN2	Btn2p	0.037
SPC105	Spc105p	0.036
TAF7	Taf7p	0.035
SWR1	Swr1p	0.035
YNL144C	hypothetical protein	0.034
PPZ1	Ppz1p	0.034
CTF8	Ctf8p	0.033
NDD1	Ndd1p	0.033
CHL1	Chl1p	0.032
GLG1	Glg1p	0.031
PAM1	Pam1p	0.031
PRR1	Prr1p	0.031
SPT7	Spt7p	0.031
MYO1	Myo1p	0.031
CRP1	Crp1p	0.031
YLR225C	hypothetical protein	0.030
IRC15	Irc15p	0.030
MTW1	Mtw1p	0.029
KSP1	Ksp1p	0.029
SWI5	Swi5p	0.029
GDI1	Gdi1p	0.028
PRE6	Pre6p	0.027
TAF2	Taf2p	0.027
RPT6	Rpt6p	0.027
CPR6	Cpr6p	0.027
MAD1	Mad1p	0.026
SRD1	Srd1p	0.026
SWC4	Swc4p	0.026
ADH2	Adh2p	0.026
RRD2	Rrd2p	0.026
ESP1	Esp1p	0.025
YLR162W	hypothetical protein	0.025
IES1	Ies1p	0.025
AFG3	Afg3p	0.025
REH1	Reh1p	0.025
MPT5	Mpt5p	0.025
SKM1	Skm1p	0.025	Human
LEU2	Leu2p	0.025
SPG3	Spg3p	0.024
YOL038C-A	hypothetical protein	0.024
CRZ1	Crz1p	0.024
CDC28	Cdc28p	0.024
GSY2	Gsy2p	0.024
MDJ1	Mdj1p	0.024	Human
YBR296C-A	hypothetical protein	0.024
COS111	Cos111p	0.023
SWD3	Swd3p	0.023
MPS1	Mps1p	0.023
YLR264C-A	hypothetical protein	0.023
FPK1	Fpk1p	0.023
TRA1	Tra1p	0.023
AHP1	Ahp1p	0.023
YLH47	Ylh47p	0.023
YIR016W	hypothetical protein	0.023
BUB1	Bub1p	0.022
PRS2	Prs2p	0.022
OPY1	Opy1p	0.022
SUR1	Sur1p	0.022
SCC2	Scc2p	0.022
SOG2	Sog2p	0.022
PTI1	Pti1p	0.022
MDM32	Mdm32p	0.022
YIL151C	hypothetical protein	0.022
BOI2	Boi2p	0.022
ZDS1	Zds1p	0.022
KIN1	Kin1p	0.021
CHA1	Cha1p	0.021
SPL2	Spl2p	0.021
SGE1	Sge1p	0.021
YNL234W	hypothetical protein	0.021
TCO89	Tco89p	0.021
HAP3	Hap3p	0.021
VPS5	Vps5p	0.021
SFI1	Sfi1p	0.021
PPN1	Ppn1p	0.021
MER1	Mer1p	0.021
CBF1	Cbf1p	0.020
UPS3	Ups3p	0.020
PDR15	Pdr15p	0.020
VAC14	Vac14p	0.020
TPI1	Tpi1p	0.020
RPN14	Rpn14p	0.020
YDL012C	hypothetical protein	0.020
YIR035C	hypothetical protein	0.020
YML053C	hypothetical protein	0.020
VHS2	Vhs2p	0.020
TAF11	Taf11p	0.020
ZDS2	Zds2p	0.020
PXA1	Pxa1p	0.019
CUP1-1	Cup1-1p	0.019
CIN1	Cin1p	0.019
SPC29	Spc29p	0.019
STE4	Ste4p	0.019
ECM27	Ecm27p	0.019
CSR2	Csr2p	0.019
STD1	Std1p	0.019
TBS1	Tbs1p	0.019
ICS2	Ics2p	0.019
PSP1	Psp1p	0.019
HMG2	Hmg2p	0.019
SLI15	Sli15p	0.019
DNM1	Dnm1p	0.019
PRP28	Prp28p	0.019
SAP190	Sap190p	0.019
NNK1	Nnk1p	0.019
PBS2	Pbs2p	0.019
CET1	Cet1p	0.019
ARE2	Are2p	0.019
GIP4	Gip4p	0.019
SIS1	Sis1p	0.018
CSL4	Csl4p	0.018
YNR062C	hypothetical protein	0.018
ATP6	Atp6p	0.018
CYM1	Cym1p	0.018
SSC1	Ssc1p	0.018
BET5	Bet5p	0.018
ARR2	Arr2p	0.018
PCT1	Pct1p	0.018
HOR2	Hor2p	0.018
YKR075C	hypothetical protein	0.018
URA3	Ura3p	0.018
YLR042C	hypothetical protein	0.018
ECM29	Ecm29p	0.018
RPT1	Rpt1p	0.018
ARP10	Arp10p	0.018
ARG8	Arg8p	0.018
YLR407W	hypothetical protein	0.017
YAR068W	hypothetical protein	0.017
TOS8	Tos8p	0.017
AHA1	Aha1p	0.017
CPD1	Cpd1p	0.017
ABZ1	Abz1p	0.017
SUI3	Sui3p	0.017
YBR013C	hypothetical protein	0.017
PPX1	Ppx1p	0.017
UBC1	Ubc1p	0.017
YJR115W	hypothetical protein	0.017
PHM6	Phm6p	0.017
THP3	Thp3p	0.017
BRN1	Brn1p	0.017
OPT2	Opt2p	0.016
CDC15	Cdc15p	0.016
PBP1	Pbp1p	0.016
SRX1	Srx1p	0.016
SPC24	Spc24p	0.016
RIB7	Rib7p	0.016
YNL024C	hypothetical protein	0.016
YPL216W	hypothetical protein	0.016
AUA1	Aua1p	0.016
YGR079W	hypothetical protein	0.016
HPF1	Hpf1p	0.016
LIF1	Lif1p	0.016
SOL1	Sol1p	0.016
MDN1	Mdn1p	0.016
HXT3	Hxt3p	0.016
YPL277C	hypothetical protein	0.016
URN1	Urn1p	0.016
FIN1	Fin1p	0.016
RAD54	Rad54p	0.016
CCT2	Cct2p	0.016
POP6	Pop6p	0.016
YMR122W-A	hypothetical protein	0.015
ZPS1	Zps1p	0.015
SWC7	Swc7p	0.015
BSC1	Bsc1p	0.015
WSS1	Wss1p	0.015
SGO1	Sgo1p	0.015
YPR157W	hypothetical protein	0.015
RRP14	Rrp14p	0.015
PPH3	Pph3p	0.015	Yeast
UFO1	Ufo1p	0.015
NTA1	Nta1p	0.015
FAU1	Fau1p	0.015
NTH2	Nth2p	0.015
SUT1	Sut1p	0.015
SPO12	Spo12p	0.015
YOL013W-A	hypothetical protein	0.015
CHK1	Chk1p	0.014
AAD15	Aad15p	0.014
MF(ALPHA)2	Mf(alpha)2p	0.014
SPS4	Sps4p	0.014
RPT4	Rpt4p	0.014
DIF1	Dif1p	0.014
SMM1	Smm1p	0.014
VPS29	Vps29p	0.014
VHS3	Vhs3p	0.014
BIO2	Bio2p	0.014
IML1	Iml1p	0.014
RAD61	Rad61p	0.014
SWI4	Swi4p	0.014
FMT1	Fmt1p	0.014
CYC7	Cyc7p	0.014
FAB1	Fab1p	0.014
PTR2	Ptr2p	0.014
SFG1	Sfg1p	0.014
AQY2	Aqy2p	0.014
VBA5	Vba5p	0.013
TIP1	Tip1p	0.013
YLR281C	hypothetical protein	0.013
ERV2	Erv2p	0.013
INP53	Inp53p	0.013
SAR1	Sar1p	0.013
SCC4	Scc4p	0.013
CTS1	Cts1p	0.013
MRK1	Mrk1p	0.013
YBL029W	hypothetical protein	0.013
MFA2	Mfa2p	0.013
AIM9	Aim9p	0.013
YAR066W	hypothetical protein	0.013
ALT2	Alt2p	0.013
PHO11	Pho11p	0.013
TPM2	Tpm2p	0.013
HO	Hop	0.013
BNA4	Bna4p	0.013
ARO10	Aro10p	0.013
YPL068C	hypothetical protein	0.013
BCK2	Bck2p	0.013
YML082W	hypothetical protein	0.013
RER2	Rer2p	0.013
YER137C	hypothetical protein	0.013
ENT1	Ent1p	0.013
DIC1	Dic1p	0.013
JLP2	Jlp2p	0.013
ENA5	Ena5p	0.013
YAL037C-A	hypothetical protein	0.013
YPL168W	hypothetical protein	0.013
BDF2	Bdf2p	0.013
YGL006W-A	hypothetical protein	0.013
RPM2	Rpm2p	0.013
YML003W	hypothetical protein	0.013
YDL119C	hypothetical protein	0.013
PZF1	Pzf1p	0.013
MSS4	Mss4p	0.013
LCB4	Lcb4p	0.013
GSY1	Gsy1p	0.013
BFA1	Bfa1p	0.013
YPR096C	hypothetical protein	0.012
YNL067W-B	hypothetical protein	0.012
RNP1	Rnp1p	0.012
YBR085C-A	hypothetical protein	0.012
TIR3	Tir3p	0.012
MET31	Met31p	0.012
CCA1	Cca1p	0.012
YJR120W	hypothetical protein	0.012
PPQ1	Ppq1p	0.012	Yeast
ATP25	Atp25p	0.012
TKL2	Tkl2p	0.012
YMR295C	hypothetical protein	0.012
PTC7	Ptc7p	0.012
RDH54	Rdh54p	0.012
RTS2	Rts2p	0.012
YBL107C	hypothetical protein	0.012
SQS1	Sqs1p	0.012
POG1	Pog1p	0.012
RFC5	Rfc5p	0.012
FCY21	Fcy21p	0.012
TYE7	Tye7p	0.012
PBP2	Pbp2p	0.012
SSA4	Ssa4p	0.012	Rat
SPT8	Spt8p	0.012
ENO1	Eno1p	0.012
IZH4	Izh4p	0.012
FAS2	Fas2p	0.012
UBC6	Ubc6p	0.012
YOR387C	hypothetical protein	0.012
FMP10	Fmp10p	0.012
YCH1	Ych1p	0.012
YNR034W-A	hypothetical protein	0.012
AAD6	Aad6p	0.012
YAL064W	hypothetical protein	0.012
PSK2	Psk2p	0.012
YGR251W	hypothetical protein	0.012
YLL053C	hypothetical protein	0.012
YLR040C	hypothetical protein	0.012
YJL147C	hypothetical protein	0.012
HAA1	Haa1p	0.012
RRN5	Rrn5p	0.012
YOL014W	hypothetical protein	0.012
IRC8	Irc8p	0.012
MF(ALPHA)1	Mf(alpha)1p	0.012
YCR102C	hypothetical protein	0.012
DUR1,2	Dur1,2p	0.012
OSH3	Osh3p	0.012
IPL1	Ipl1p	0.012
NRG2	Nrg2p	0.012
YJL055W	hypothetical protein	0.012
COS12	Cos12p	0.012
CUR1	Cur1p	0.012
MTM1	Mtm1p	0.012
EXO70	Exo70p	0.012
OYE3	Oye3p	0.012
YDR222W	hypothetical protein	0.012
SWC3	Swc3p	0.012
NUD1	Nud1p	0.011
RPN2	Rpn2p	0.011
GAL83	Gal83p	0.011
RAD53	Rad53p	0.011
UFD2	Ufd2p	0.011
RPN7	Rpn7p	0.011
YKR041W	hypothetical protein	0.011
YFR016C	hypothetical protein	0.011
YMR317W	hypothetical protein	0.011
YDR034C-A	hypothetical protein	0.011
MAG1	Mag1p	0.011
ATO3	Ato3p	0.011
PMA2	Pma2p	0.011
YHR033W	hypothetical protein	0.011
SNF3	Snf3p	0.011
LCL1	Lcl1p	0.011
STB2	Stb2p	0.011
DAL82	Dal82p	0.011
YHR177W	hypothetical protein	0.011
TAD2	Tad2p	0.011
YIR014W	hypothetical protein	0.011
BIT61	Bit61p	0.011
AZF1	Azf1p	0.011
KEL2	Kel2p	0.011
YOR012W	hypothetical protein	0.011
REE1	Ree1p	0.011
FRE5	Fre5p	0.011
YGK3	Ygk3p	0.011
RPN11	Rpn11p	0.011
YNL033W	hypothetical protein	0.011
PRM4	Prm4p	0.011
AIM18	Aim18p	0.011
AAC3	Aac3p	0.011
TSC3	Tsc3p	0.011
TIF4632	Tif4632p	0.011
RED1	Red1p	0.011
UTP11	Utp11p	0.011
YPL067C	hypothetical protein	0.011
SMC4	Smc4p	0.011
DOG1	Dog1p	0.011
RPT3	Rpt3p	0.011
RKR1	Rkr1p	0.011
YMR210W	hypothetical protein	0.011
TOR1	Tor1p	0.011
NCE103	Nce103p	0.011
NCS6	Ncs6p	0.011
YNL058C	hypothetical protein	0.011
TAH11	Tah11p	0.011
YDL085C-A	hypothetical protein	0.011
MBF1	Mbf1p	0.011
YKR045C	hypothetical protein	0.011
YIR042C	hypothetical protein	0.011
HAL5	Hal5p	0.011
HAP1	Hap1p	0.011
PHD1	Phd1p	0.011
YCR015C	hypothetical protein	0.011
FOL3	Fol3p	0.011
GIP3	Gip3p	0.011
HMRA1	Hmra1p	0.011
ZRG8	Zrg8p	0.011
SMC5	Smc5p	0.011
YBR138C	hypothetical protein	0.011
YNL162W-A	hypothetical protein	0.011
YJL160C	hypothetical protein	0.011
YHP1	Yhp1p	0.010
TID3	Tid3p	0.010
POM34	Pom34p	0.010
YLR412C-A	hypothetical protein	0.010
YKL187C	hypothetical protein	0.010
MUB1	Mub1p	0.010
YNL018C	hypothetical protein	0.010
YER163C	hypothetical protein	0.010
SRO77	Sro77p	0.010
YOR338W	hypothetical protein	0.010
AVO1	Avo1p	0.010
FAA2	Faa2p	0.010
AIM11	Aim11p	0.010
YLR363W-A	hypothetical protein	0.010
SET4	Set4p	0.010
YJL218W	hypothetical protein	0.010
CTF19	Ctf19p	0.010
CAB1	Cab1p	0.010
BAT2	Bat2p	0.010
PNS1	Pns1p	0.010
DCD1	Dcd1p	0.010
BUD8	Bud8p	0.010
APM4	Apm4p	0.010
MET8	Met8p	0.010
YPR015C	hypothetical protein	0.010
VEL1	Vel1p	0.010
RTT105	Rtt105p	0.010
YPL113C	hypothetical protein	0.010
SRT1	Srt1p	0.010
INN1	Inn1p	0.010
IMA2	Ima2p	0.010
SPS100	Sps100p	0.010
BI4	Bi4p	0.010
GDB1	Gdb1p	0.010
SCM4	Scm4p	0.010
FRQ1	Frq1p	0.010