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Process View

Danio rerio

12 genes annotated in zebrafish

chromosome segregation

The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chromosome segregation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chromosome segregation" (in gray)

Name	Description	Probability	Func Analog Organism
sass6	spindle assembly 6 homolog (C. elegans)	0.880
ccnb1	cyclin B1	0.869	Human Fly
ccnb2	cyclin B2	0.460	Fly
ccna2	cyclin A2	0.444
piwil1	piwi-like 1 (Drosophila)	0.403	Fly
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.367
ncapg	non-SMC condensin I complex, subunit G	0.334
pbx4	pre-B-cell leukemia transcription factor 4	0.318
ncapd2	non-SMC condensin I complex, subunit D2	0.296
plk1	polo-like kinase 1 (Drosophila)	0.275	Human Yeast Worm
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.253	Fly
zgc:110113	zgc:110113	0.210
lamc1	laminin, gamma 1	0.182
nanos3	nanos homolog 3	0.173	Fly
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.167
cdh1	cadherin 1, epithelial	0.164
ccne	cyclin E	0.154	Fly
hoxa9b	homeo box A9b	0.141	Fly
dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.138
psmc6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.138
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.136	Fly
smc4	structural maintenance of chromosomes 4	0.119	Human Yeast Mouse Worm
top2a	topoisomerase (DNA) II alpha	0.119
smc1al	structural maintenance of chromosomes 1A, like	0.117	Human Worm
zgc:56200	zgc:56200	0.115
tyms	thymidylate synthase	0.113
si:ch211-244o22.2	si:ch211-244o22.2	0.103
hug	HuG	0.100
hoxd9a	homeo box D9a	0.095	Fly
si:ch211-69g19.2	si:ch211-69g19.2	0.092
msh6	mutS homolog 6 (E. coli)	0.090
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.088
melk	maternal embryonic leucine zipper kinase	0.082
hoxa10b	homeo box A10b	0.080	Fly
suv39h1b	suppressor of variegation 3-9 homolog 1b	0.074
kif23	kinesin family member 23	0.070	Fly
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.069
mcm6	MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)	0.069
wdr45	WD repeat domain 45	0.067
ube2i2	ubiquitin-conjugating enzyme E2I2	0.066	Fly
ahctf1	AT hook containing transcription factor 1	0.064
csnk1da	casein kinase 1, delta a	0.064	Yeast
dnmt1	DNA (cytosine-5-)-methyltransferase 1	0.063
zgc:65861	zgc:65861	0.062
chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.061	Mouse
buc	bucky ball	0.059
dtl	denticleless homolog (Drosophila)	0.057
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.057	Fly
ctps	CTP synthase	0.057
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.056	Fly
smc2	structural maintenance of chromosomes 2	0.055	Human Yeast Mouse Worm Fly
rrm1	ribonucleotide reductase M1 polypeptide	0.054
asz1	ankyrin repeat, SAM and basic leucine zipper domain containing 1	0.054
wu:fi04f09	wu:fi04f09	0.052
rpa2	replication protein A2	0.052
fn1	fibronectin 1	0.052
dnmt5	DNA (cytosine-5-)-methyltransferase 5	0.051
hoxd11a	homeo box D11a	0.048
chaf1b	chromatin assembly factor 1, subunit B	0.048
mybl2	myeloblastosis oncogene-like 2	0.047
racgap1	Rac GTPase-activating protein 1	0.046	Human
cep55l	centrosomal protein 55 like	0.046
aurka	aurora kinase A	0.045	Yeast Zebrafish Worm
zgc:153910	zgc:153910	0.045
rbl1	retinoblastoma-like 1 (p107)	0.045	Fly
brca2	breast cancer 2, early onset	0.045
cdt1	chromatin licensing and DNA replication factor 1	0.045	Fly
hoxa13b	homeo box A13b	0.045
hoxc9a	homeo box C9a	0.044
srsf1a	serine/arginine-rich splicing factor 1a	0.042
snx5	sorting nexin 5	0.042
aurkb	aurora kinase B	0.040
im:7140452	im:7140452	0.040
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.039
prkci	protein kinase C, iota	0.039
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.037
zgc:92775	zgc:92775	0.036
psmb3	proteasome (prosome, macropain) subunit, beta type, 3	0.036
zgc:91910	zgc:91910	0.036
zgc:110380	zgc:110380	0.035	Worm
ipo9	importin 9	0.034
depdc1a	DEP domain containing 1a	0.034
mos	v-mos Moloney murine sarcoma viral oncogene homolog	0.034
tuba7l	tubulin, alpha 7 like	0.034	Fly
zgc:101661	zgc:101661	0.033
pbrm1l	polybromo 1, like	0.032
csnk1g2a	casein kinase 1, gamma 2a	0.031
dut	dUTP pyrophosphatase	0.031
rtkn2	rhotekin 2	0.031
psmb4	proteasome (prosome, macropain) subunit, beta type, 4	0.031
rae1	RAE1 RNA export 1 homolog (S. pombe)	0.031
arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.031
whsc1	Wolf-Hirschhorn syndrome candidate 1	0.030
pole2	polymerase (DNA directed), epsilon 2	0.030
LOC100151531	zinc finger protein Gfi-1b-like	0.029
dnaja2l	DnaJ (Hsp40) homolog, subfamily A, member 2, like	0.029
prc1b	protein regulator of cytokinesis 1b	0.028
capza1a	capping protein (actin filament) muscle Z-line, alpha 1a	0.028
fkbp1aa	FK506 binding protein 1Aa	0.028
znf711	zinc finger protein 711	0.028
esco2	establishment of cohesion 1 homolog 2	0.028
cdc25	cell division cycle 25 homolog	0.028
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.027
hells	helicase, lymphoid-specific	0.027
im:6898523	im:6898523	0.027
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.027
zgc:174506	zgc:174506	0.026	Human
org	oogenesis-related gene	0.026
dazl	daz-like gene	0.026
kifc1	kinesin family member C1	0.026
ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.026
wu:fl55e11	wu:fl55e11	0.026
birc5b	baculoviral IAP repeat-containing 5B	0.026
si:dkey-74f15.3	si:dkey-74f15.3	0.025
nop58	NOP58 ribonucleoprotein homolog (yeast)	0.024
cdc20	cell division cycle 20 homolog	0.024	Yeast Worm Fly
si:ch211-215h6.2	si:ch211-215h6.2	0.024
psmb1	proteasome (prosome, macropain) subunit, beta type, 1	0.024
psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.024
nap1l4b	nucleosome assembly protein 1-like 4b	0.024
zff9	zinc finger protein 9	0.024
mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.024	Human Mouse Worm
cand1	cullin-associated and neddylation-dissociated 1	0.024
pola1	polymerase (DNA directed), alpha 1	0.023
arpc5a	actin related protein 2/3 complex, subunit 5A	0.023
skp2	S-phase kinase-associated protein 2 (p45)	0.023
twist1a	twist1a	0.023
si:dkeyp-35b8.5	si:dkeyp-35b8.5	0.023
actr1	ARP1 actin-related protein 1, centractin (yeast)	0.022
nusap1	nucleolar and spindle associated protein 1	0.022	Human
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.022
snx12	sorting nexin 12	0.022
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.022
pou5f1	POU domain, class 5, transcription factor 1	0.022
lamb1a	laminin, beta 1a	0.022
h1fx	H1 histone family, member X	0.021	Worm
tacc3	transforming, acidic coiled-coil containing protein 3	0.021
actl6a	actin-like 6A	0.021
atp1b3b	ATPase, Na+/K+ transporting, beta 3b polypeptide	0.021
nrf1	nuclear respiratory factor 1	0.021
e2f5	E2F transcription factor 5	0.020
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.020
zgc:111944	zgc:111944	0.020
psma8	proteasome (prosome, macropain) subunit, alpha type, 8	0.020
hhip	hedgehog interacting protein	0.020
prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.020
zgc:110434	zgc:110434	0.020
si:ch211-278b8.3	si:ch211-278b8.3	0.020
fancl	Fanconi anemia, complementation group L	0.019
mapk15	mitogen-activated protein kinase 15	0.019
bsdc1	BSD domain containing 1	0.019
slbp	stem-loop binding protein	0.019	Worm Fly
msh2	mutS homolog 2 (E. coli)	0.019
hoxa11b	homeo box A11b	0.018
zgc:153369	zgc:153369	0.018
lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.018
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.018	Worm
si:ch211-197n10.2	si:ch211-197n10.2	0.018
si:dkey-14d8.6	si:dkey-14d8.6	0.018
tipin	timeless interacting protein	0.018
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.018
gnl2	guanine nucleotide binding protein-like 2 (nucleolar)	0.018
sybu	syntabulin (syntaxin-interacting)	0.017
hn1l	hematological and neurological expressed 1-like	0.017
pgam1b	phosphoglycerate mutase 1b	0.017
mettl3	methyltransferase like 3	0.017
LOC100536090	targeting protein for Xklp2-B-like	0.017
usp5	ubiquitin specific protease 5	0.017
snx27	sorting nexin family member 27	0.017
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.017
gdi2	GDP dissociation inhibitor 2	0.016
poc1a	POC1 centriolar protein homolog A (Chlamydomonas)	0.016
vasa	vasa homolog	0.016	Fly
mcmbp	minichromosome maintenance complex binding protein	0.016	Human
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.016	Fly
arih2	ariadne homolog 2 (Drosophila)	0.016
psmb2	proteasome (prosome, macropain) subunit, beta type, 2	0.016
smap1	stromal membrane-associated protein 1	0.016
ttc35	tetratricopeptide repeat domain 35	0.016
taf9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.016
rbmx	RNA binding motif protein, X-linked	0.016
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.016
rcc2	regulator of chromosome condensation 2	0.016	Human
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.016
arf2	ADP-ribosylation factor 2	0.016
lamb2	laminin, beta 2 (laminin S)	0.016
usp1	ubiquitin specific protease 1	0.016
xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.016
hoxd13a	homeo box D13a	0.016
ck2b	casein kinase 2 beta	0.015
sept7a	septin 7a	0.015
fbn2b	fibrillin 2b	0.015
zgc:123326	zgc:123326	0.015
dnmt3	DNA (cytosine-5-)-methyltransferase 3	0.015
cpa1	carboxypeptidase A1 (pancreatic)	0.015
gins2	GINS complex subunit 2	0.015
rrm2	ribonucleotide reductase M2 polypeptide	0.015
vps26bl	vacuolar protein sorting 26 homolog B, like	0.015
hist2h3ca1	histone 2, H3ca1	0.015
ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.015	Human Worm
si:ch211-260p9.1	si:ch211-260p9.1	0.015
smad9	MAD homolog 9 (Drosophila)	0.015
ep300b	E1A binding protein p300 b	0.015
naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.015
zorba	Orb/CPEB-related RNA-binding protein	0.014
zgc:153997	zgc:153997	0.014
zgc:92237	zgc:92237	0.014
mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.014	Worm
fam60al	family with sequence similarity 60, member A, like	0.014
robo3	roundabout homolog 3	0.014
krcp	kelch repeat-containing protein	0.014
fmr1	fragile X mental retardation 1	0.014
gins3	GINS complex subunit 3	0.014
acvr1l	activin A receptor, type I like	0.014
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.014
arpc1a	actin related protein 2/3 complex, subunit 1A	0.014
atad5a	ATPase family, AAA domain containing 5a	0.014
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.014
kidins220b	kinase D-interacting substrate of 220b	0.014
ttc25	tetratricopeptide repeat domain 25	0.013
kdm5c	lysine (K)-specific demethylase 5C	0.013
ptena	phosphatase and tensin homolog A	0.013	Human Mouse
si:ch211-1n9.7	si:ch211-1n9.7	0.013
rb1	retinoblastoma 1	0.013
map2k4b	mitogen-activated protein kinase kinase 4b	0.013
zgc:113143	zgc:113143	0.013
zgc:92661	zgc:92661	0.013
krit1	KRIT1, ankyrin repeat containing	0.013
smc3	structural maintenance of chromosomes 3	0.013
pola2	polymerase (DNA directed), alpha 2	0.013
tpd52l2b	tumor protein D52-like 2b	0.013
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.013
zgc:112368	zgc:112368	0.013
snrpa	small nuclear ribonucleoprotein polypeptide A	0.013
zgc:64116	zgc:64116	0.013	Human
mcm3	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)	0.013
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.013	Yeast
papolg	poly(A) polymerase gamma	0.012
zgc:110540	zgc:110540	0.012
hoxd10a	homeo box D10a	0.012	Fly
axin1	axin 1	0.012
terfa	telomeric repeat binding factor a	0.012
dynlrb1	dynein, light chain, roadblock-type 1	0.012
inhbaa	inhibin, beta Aa	0.012
zgc:55741	zgc:55741	0.012
nosip	nitric oxide synthase interacting protein	0.012
zgc:112980	zgc:112980	0.012
dctn2	dynactin 2 (p50)	0.012	Worm
uba2	ubiquitin-like modifier activating enzyme 2	0.012
matr3l	matrin 3-like	0.012
ttk	ttk protein kinase	0.012
wdhd1	WD repeat and HMG-box DNA binding protein 1	0.012
shcbp1	SHC SH2-domain binding protein 1	0.012
rfc4	replication factor C (activator 1) 4	0.012
pold2	polymerase (DNA directed), delta 2, regulatory subunit	0.012
copb2	coatomer protein complex, subunit beta 2	0.012
adka	adenosine kinase a	0.012
magt1	magnesium transporter 1	0.012
cdca8	cell division cycle associated 8	0.012	Human
arpp19a	cAMP-regulated phosphoprotein 19a	0.011
smx5	smx5	0.011
hmgb2a	high-mobility group box 2a	0.011
wu:fd23d07	wu:fd23d07	0.011
cdc42	cell division cycle 42	0.011	Human
h3f3a	H3 histone, family 3A	0.011
tnrc5	trinucleotide repeat containing 5	0.011
mapk14a	mitogen-activated protein kinase 14a	0.011	Human
zgc:154089	zgc:154089	0.011
rab2a	RAB2A, member RAS oncogene family	0.011
napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.011
caprin2	caprin family member 2	0.011
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.011
hpca	hippocalcin	0.011
arpc4	actin related protein 2/3 complex, subunit 4	0.011
tob1a	transducer of ERBB2, 1a	0.011
plk3	polo-like kinase 3 (Drosophila)	0.011	Yeast
smndc1	survival motor neuron domain containing 1	0.011
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.011
tbc1d23	TBC1 domain family, member 23	0.011
zgc:110687	zgc:110687	0.011
si:ch211-147d7.3	si:ch211-147d7.3	0.011
amd1	adenosylmethionine decarboxylase 1	0.011
pfn2	profilin 2	0.011
pprc1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.010
ybx1	Y box binding protein 1	0.010
eef2k	elongation factor-2 kinase	0.010
kif20bb	kinesin family member 20Bb	0.010
tmpoa	thymopoietin a	0.010
zgc:103627	zgc:103627	0.010
ca15b	carbonic anhydrase XV b	0.010
map2k4a	mitogen-activated protein kinase kinase 4a	0.010
amy2a	amylase, alpha 2A; pancreatic	0.010
im:7150454	im:7150454	0.010
ergic2	ERGIC and golgi 2	0.010
ufd1l	ubiquitin fusion degradation 1-like	0.010
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.010
lama1	laminin, alpha 1	0.010
LOC565256	similar to Metabotropic glutamate receptor 3 precursor (mGluR3)	0.010
nolc1	nucleolar and coiled-body phosphoprotein 1	0.010
med24	mediator complex subunit 24	0.010
map2k7	mitogen-activated protein kinase kinase 7	0.010