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Danio rerio

9 genes annotated in zebrafish

negative regulation of cell cycle process

Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cell cycle process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cell cycle process" (in gray)

Name	Description	Probability	Func Analog Organism
ccnb1	cyclin B1	0.568	Human
map2k4a	mitogen-activated protein kinase kinase 4a	0.371
smad9	MAD homolog 9 (Drosophila)	0.363	Fly
smc4	structural maintenance of chromosomes 4	0.348
wnt4a	wingless-type MMTV integration site family, member 4a	0.310	Zebrafish
nrg1	neuregulin 1	0.295
kif23	kinesin family member 23	0.267
ccnb2	cyclin B2	0.261
dtl	denticleless homolog (Drosophila)	0.231
ccna2	cyclin A2	0.214
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.212
skp2	S-phase kinase-associated protein 2 (p45)	0.203
ccnd1	cyclin D1	0.196	Human
wdhd1	WD repeat and HMG-box DNA binding protein 1	0.180
plk1	polo-like kinase 1 (Drosophila)	0.163	Human
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.163
oep	one-eyed pinhead	0.152
csnk1da	casein kinase 1, delta a	0.146
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.144
nusap1	nucleolar and spindle associated protein 1	0.142
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.140	Fly
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.134
wnt11r	wingless-type MMTV integration site family, member 11, related	0.133	Zebrafish
orc6	origin recognition complex, subunit 6	0.128
mos	v-mos Moloney murine sarcoma viral oncogene homolog	0.102	Mouse
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.097
zgc:174506	zgc:174506	0.084
e2f5	E2F transcription factor 5	0.081	Fly
bon	bonnie and clyde	0.081
krcp	kelch repeat-containing protein	0.074
tgif1	TGFB-induced factor homeobox 1	0.063
cand1	cullin-associated and neddylation-dissociated 1	0.063
mapk3	mitogen-activated protein kinase 3	0.063
baxa	bcl2-associated X protein, a	0.062	Zebrafish
si:ch211-244o22.2	si:ch211-244o22.2	0.061
fabp7a	fatty acid binding protein 7, brain, a	0.061
twist1b	twist1b	0.061
slbp	stem-loop binding protein	0.059
ncapg	non-SMC condensin I complex, subunit G	0.059
si:ch211-173o4.2	si:ch211-173o4.2	0.059
cep55l	centrosomal protein 55 like	0.057
fgf17	fibroblast growth factor 17	0.054
bmp2b	bone morphogenetic protein 2b	0.054
cdc20	cell division cycle 20 homolog	0.053	Yeast
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.052	Fly
depdc1a	DEP domain containing 1a	0.052
melk	maternal embryonic leucine zipper kinase	0.050
wnt1	wingless-type MMTV integration site family, member 1	0.049	Zebrafish Fly
emx2	empty spiracles homeobox 2	0.048
zgc:110113	zgc:110113	0.048
tp53	tumor protein p53	0.047	Human Mouse
wnt5b	wingless-type MMTV integration site family, member 5b	0.047	Zebrafish
stil	TAL1 (SCL) interrupting locus	0.046	Mouse
cdt1	chromatin licensing and DNA replication factor 1	0.045
fgf3	fibroblast growth factor 3	0.044
LOC100536090	targeting protein for Xklp2-B-like	0.044
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.043
lrp2	low density lipoprotein-related protein 2	0.042
tgfb3	transforming growth factor, beta 3	0.042
mettl2a	methyltransferase like 2A	0.041
pou5f1	POU domain, class 5, transcription factor 1	0.041
zgc:92321	zgc:92321	0.041
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.040
dusp1	dual specificity phosphatase 1	0.039
sox32	SRY-box containing gene 32	0.038
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.038
wnt10a	wingless-type MMTV integration site family, member 10a	0.038	Zebrafish
sid4	secreted immunoglobulin domain 4	0.037
vcana	versican a	0.036
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.036
smc1al	structural maintenance of chromosomes 1A, like	0.035	Human
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.035
caprin1a	cell cycle associated protein 1a	0.033
arl4ab	ADP-ribosylation factor-like 4ab	0.033
id1	inhibitor of DNA binding 1	0.032	Zebrafish
rbl1	retinoblastoma-like 1 (p107)	0.031	Fly
snrpc	small nuclear ribonucleoprotein polypeptide C	0.031
wnt8b	wingless-type MMTV integration site family, member 8b	0.030	Zebrafish
lef1	lymphocyte enhancer binding factor 1	0.030
ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.030
ccnt2b	cyclin T2b	0.030
zgc:113210	zgc:113210	0.030
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.029
cdk2	cyclin-dependent kinase 2	0.029	Yeast
ptmaa	prothymosin, alpha a	0.029
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.029
szl	sizzled	0.029
prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.028
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.028
fbxl14a	F-box and leucine-rich repeat protein 14a	0.028
ezh2	enhancer of zeste homolog 2 (Drosophila)	0.028	Mouse
sox11a	SRY-box containing gene 11a	0.028
sass6	spindle assembly 6 homolog (C. elegans)	0.028
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.027
tuba7l	tubulin, alpha 7 like	0.027	Fly
crestin	crestin	0.027
zar1	zygote arrest 1	0.027
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.026
pax7a	paired box gene 7a	0.026
zgc:110540	zgc:110540	0.026
zff9	zinc finger protein 9	0.026
suv39h1b	suppressor of variegation 3-9 homolog 1b	0.026
morf4l1	mortality factor 4 like 1	0.026
zgc:153910	zgc:153910	0.025
hug	HuG	0.025
flh	floating head	0.025
dzip1	DAZ interacting protein 1	0.025
pcna	proliferating cell nuclear antigen	0.024
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.024	Fly
hmx1	H6 homeo box 1	0.024
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.024
wdr82	WD repeat domain containing 82	0.024
fen1	flap structure-specific endonuclease 1	0.024
si:ch211-69g19.2	si:ch211-69g19.2	0.024
wnt9b	wingless-type MMTV integration site family, member 9B	0.024	Zebrafish
ncapd2	non-SMC condensin I complex, subunit D2	0.023
rtkn2	rhotekin 2	0.023
cul3a	cullin 3a	0.023
gins3	GINS complex subunit 3	0.023
ccne	cyclin E	0.022	Fly
cdca8	cell division cycle associated 8	0.022
LOC100000597	hypothetical protein LOC100000597	0.022
pak2b	p21 (CDKN1A)-activated kinase 2b	0.022
c20orf14	c20orf14 homolog (H. sapiens)	0.022
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.022
btg2	B-cell translocation gene 2	0.021
zgc:55347	zgc:55347	0.021
cry5	cryptochrome 5	0.021
mycl1a	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) a	0.021
hdac3	histone deacetylase 3	0.021
fbxw2	F-box and WD repeat domain containing 2	0.021
trip13	thyroid hormone receptor interactor 13	0.021
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.021	Zebrafish
orc1	origin recognition complex, subunit 1	0.021
tgfbr2	transforming growth factor, beta receptor II	0.020
ung	uracil-DNA glycosylase	0.020
rarga	retinoic acid receptor gamma a	0.020
eaf2	ELL associated factor 2	0.020
kpna3	karyopherin (importin) alpha 3	0.020	Fly
elk4	ELK4, ETS-domain protein	0.020
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.019
cct8	chaperonin containing TCP1, subunit 8 (theta)	0.019
rqcd1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.019
lzts2a	leucine zipper, putative tumor suppressor 2a	0.019
smarcb1a	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a	0.019
ubin	ataxin-1 ubiquitin-like interacting protein	0.019
ttk	ttk protein kinase	0.019
rbpms2	RNA binding protein with multiple splicing 2	0.019
prpf40a	PRP40 pre-mRNA processing factor 40 homolog A (yeast)	0.019
cops3	COP9 constitutive photomorphogenic homolog subunit 3	0.019
im:6907928	im:6907928	0.019
snrpd1	small nuclear ribonucleoprotein D1 polypeptide	0.018
ola1	Obg-like ATPase 1	0.018
zgc:56200	zgc:56200	0.018
tbx16	T-box gene 16	0.018
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.018
atf4b1	activating transcription factor 4b1 (tax-responsive enhancer element B67)	0.018
rad21	RAD21 homolog (S. pombe)	0.018
uba3	ubiquitin-like modifier activating enzyme 3	0.018
myst2	MYST histone acetyltransferase 2	0.018
mcl1b	myeloid cell leukemia sequence 1b	0.018
tbc1d23	TBC1 domain family, member 23	0.018
prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.017
hspb1	heat shock protein, alpha-crystallin-related, 1	0.017
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.017	Fly
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.017
rhoab	ras homolog gene family, member Ab	0.017
mcm6	MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)	0.017
crip2	cysteine-rich protein 2	0.017
map2k6	mitogen-activated protein kinase kinase 6	0.017
rasl11b	RAS-like, family 11, member B	0.016
angpt1	angiopoietin 1	0.016
ube2i	ubiquitin-conjugating enzyme E2I	0.016	Fly
aurka	aurora kinase A	0.016	Yeast Mouse
matr3l	matrin 3-like	0.016
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.016
ctnnbl1	catenin, beta like 1	0.016
ergic2	ERGIC and golgi 2	0.016
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.016
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.015
mapk7	mitogen-activated protein kinase 7	0.015
rargb	retinoic acid receptor, gamma b	0.015
zc3h13	zinc finger CCCH-type containing 13	0.015
acvr1l	activin A receptor, type I like	0.015
gmnn	geminin, DNA replication inhibitor	0.015
rpa3	replication protein A3	0.015
fktn	fukutin	0.015
pknox1.2	pbx/knotted 1 homeobox 1.2	0.014
ybx1	Y box binding protein 1	0.014
lrrc40	leucine rich repeat containing 40	0.014
arhgap11a	Rho GTPase activating protein 11A	0.014
tardbpl	TAR DNA binding protein, like	0.014
usp1	ubiquitin specific protease 1	0.014
tacc3	transforming, acidic coiled-coil containing protein 3	0.014
wnt16	wingless-type MMTV integration site family, member 16	0.014
smc3	structural maintenance of chromosomes 3	0.014	Human
zgc:162965	zgc:162965	0.014
mbnl1	muscleblind-like (Drosophila)	0.014
myod1	myogenic differentiation 1	0.014
zgc:113183	zgc:113183	0.013
eif3ha	eukaryotic translation initiation factor 3, subunit H, a	0.013
ccnl1	cyclin L1	0.013
ccnk	cyclin K	0.013
entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.013
glmna	glomulin, FKBP associated protein a	0.013
LOC566708	FL cytokine receptor-like	0.013
cdc42l	cell division cycle 42, like	0.013
dlc	deltaC	0.013
zgc:55876	zgc:55876	0.013
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.013
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.013	Fly
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.013
eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha	0.012
eif3d	eukaryotic translation initiation factor 3, subunit D	0.012
sfrp1a	secreted frizzled-related protein 1a	0.012
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.012
sae1	SUMO1 activating enzyme subunit 1	0.012
gtf2h2	general transcription factor IIH, polypeptide 2	0.012
hnrpl	heterogeneous nuclear ribonucleoprotein L	0.012
tbpl2	TATA box binding protein like 2	0.012
haus6	HAUS augmin-like complex, subunit 6	0.012
map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.012
klhl11	kelch-like 11 (Drosophila)	0.012
gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.012
wdr5	WD repeat domain 5	0.012	Fly
wnt10b	wingless-type MMTV integration site family, member 10b	0.012	Zebrafish
org	oogenesis-related gene	0.012
znf207b	zinc finger protein 207, b	0.011	Human
paf1	paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.011
med28	mediator complex subunit 28	0.011
eif2d	eukaryotic translation initiation factor 2D	0.011
im:7153552	im:7153552	0.011
nup107	nucleoporin 107	0.011
cstf3	cleavage stimulation factor, 3' pre-RNA, subunit 3	0.011
zgc:103670	zgc:103670	0.011
ptp4a3	protein tyrosine phosphatase type IVA, member 3	0.011
zorba	Orb/CPEB-related RNA-binding protein	0.011
luc7l	LUC7-like (S. cerevisiae)	0.011
actn4	actinin, alpha 4	0.011
lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.011
rbb4l	retinoblastoma binding protein 4, like	0.011
twist1a	twist1a	0.011
zgc:56197	zgc:56197	0.011
smndc1	survival motor neuron domain containing 1	0.011
rcc2	regulator of chromosome condensation 2	0.011
rbb4	retinoblastoma binding protein 4	0.011
lpp	LIM domain containing preferred translocation partner in lipoma	0.011
cdc42	cell division cycle 42	0.010
tubgcp2	tubulin, gamma complex associated protein 2	0.010
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.010
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.010
lhx2b	LIM homeobox 2b	0.010
gpr126	G protein-coupled receptor 126	0.010
ptena	phosphatase and tensin homolog A	0.010	Human
mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.010	Human Mouse Worm
eif4e1b	eukaryotic translation initiation factor 4e 1b	0.010