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Process View

Danio rerio

5 genes annotated in zebrafish

anterior posterior axon guidance

The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "anterior posterior axon guidance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "anterior posterior axon guidance" (in gray)

Name	Description	Probability	Func Analog Organism
lhx2b	LIM homeobox 2b	1.000
boc	brother of CDO	0.998
robo3	roundabout homolog 3	0.990	Zebrafish
shha	sonic hedgehog a	0.922
smo	smoothened homolog (Drosophila)	0.831
tbx1	T-box 1	0.817
robo2	roundabout homolog 2	0.811
evx1	even-skipped homeobox 1	0.808
tbx2b	T-box 2b	0.766
ptch2	patched 2	0.755
fgf3	fibroblast growth factor 3	0.639
msxc	muscle segment homeobox C	0.635
fgfr3	fibroblast growth factor receptor 3	0.575
slit2	slit (Drosophila) homolog 2	0.535
dla	deltaA	0.465
dzip1	DAZ interacting protein 1	0.427
slit3	slit (Drosophila) homolog 3	0.406	Zebrafish
lef1	lymphocyte enhancer binding factor 1	0.391
pax2a	paired box gene 2a	0.387
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.333
prdm1a	PR domain containing 1a, with ZNF domain	0.309
twist1a	twist1a	0.306
wnt3	wingless-type MMTV integration site family, member 3	0.269
foxd3	forkhead box D3	0.232
gli1	GLI-Kruppel family member 1	0.227
hoxa13b	homeo box A13b	0.214
znf503	zinc finger protein 503	0.211
ntn1a	netrin 1a	0.200
tnc	tenascin C	0.191
ndr2	nodal-related 2	0.188
foxp2	forkhead box P2	0.186
nrp1a	neuropilin 1a	0.178
irx1a	iroquois homeobox protein 1, a	0.177
sox9a	SRY-box containing gene 9a	0.174
epha4a	eph receptor A4a	0.174
cdh2	cadherin 2, neuronal	0.171
tfap2a	transcription factor AP-2 alpha	0.171
fzd9b	frizzled homolog 9b	0.166
zgc:158603	zgc:158603	0.164
disp1	dispatched homolog 1 (Drosophila)	0.163
twist3	twist3	0.160
sema3d	semaphorin 3d	0.158
robo1	roundabout homolog 1	0.153	Zebrafish
scube2	signal peptide, CUB domain, EGF-like 2	0.133
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.133
neurog1	neurogenin 1	0.127
msxd	muscle segment homeobox D	0.117
dbx1a	developing brain homeobox 1a	0.114
wnt5b	wingless-type MMTV integration site family, member 5b	0.112	Worm
sec24d	SEC24 family, member D (S. cerevisiae)	0.112
gli2a	GLI-Kruppel family member GLI2a	0.111
gli2b	GLI-Kruppel family member GLI2b	0.109
arx	aristaless related homeobox	0.103
bmp2b	bone morphogenetic protein 2b	0.102
ephb4b	eph receptor B4b	0.101
dlx2a	distal-less homeobox gene 2a	0.098
emx3	empty spiracles homeobox 3	0.090
bmp2a	bone morphogenetic protein 2a	0.089
foxa1	forkhead box A1	0.089
nkd1	naked cuticle homolog 1 (Drosophila)	0.088
emx1	empty spiracles homeobox 1	0.086
wnt8b	wingless-type MMTV integration site family, member 8b	0.082
efnb3b	ephrin B3b	0.082
notch3	notch homolog 3	0.082
slit1a	slit homolog 1a (Drosophila)	0.082	Zebrafish
nova2	neuro-oncological ventral antigen 2	0.081
efnb2a	ephrin B2a	0.079
hhip	hedgehog interacting protein	0.077
edn1	endothelin 1	0.074
hoxa11b	homeo box A11b	0.073
bmp4	bone morphogenetic protein 4	0.072
six3b	sine oculis homeobox homolog 3b	0.072
wnt4a	wingless-type MMTV integration site family, member 4a	0.071
neurod4	neurogenic differentiation 4	0.069
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.063
fgf10a	fibroblast growth factor 10a	0.060
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.058
axin1	axin 1	0.055
igfbp3	insulin-like growth factor binding protein 3	0.055
spry4	sprouty (Drosophila) homolog 4	0.055
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.053
sp8a	sp8 transcription factor a	0.053
ephb4a	eph receptor B4a	0.053
cyfip2	cytoplasmic FMR1 interacting protein 2	0.052
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.052
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.052
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.052
tbx5a	T-box 5a	0.051
fezf2	FEZ family zinc finger 2	0.050
neo1	neogenin 1	0.050
sfrp1a	secreted frizzled-related protein 1a	0.050
pbx4	pre-B-cell leukemia transcription factor 4	0.048
hoxa13a	homeo box A13a	0.048
tac1	tachykinin 1	0.048
extl3	exostoses (multiple)-like 3	0.047
skia	nuclear oncoprotein skia	0.046
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.045
sema3aa	semaphorin 3aa	0.044
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.041
scrt1a	scratch homolog 1, zinc finger protein a (Drosophila)	0.040
mycbp2	MYC binding protein 2	0.039
epb4.1l4	erythrocyte protein band 4.1-like 4	0.039
gle1	GLE1 RNA export mediator homolog (yeast)	0.038
axin2	axin 2 (conductin, axil)	0.038
chsy1	chondroitin sulfate synthase 1	0.037
hoxa11a	homeo box A11a	0.036
hoxb3a	homeo box B3a	0.035
tbx2a	T-box gene 2a	0.035
hoxa9a	homeo box A9a	0.034
ext2	exostoses (multiple) 2	0.033	Zebrafish
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.032
fstl1b	follistatin-like 1b	0.032
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.032
dusp6	dual specificity phosphatase 6	0.031
barhl2	BarH-like 2	0.031
efna3b	ephrin A3b	0.029
gsna	gelsolin a	0.028
alcamb	activated leukocyte cell adhesion molecule b	0.028
rarga	retinoic acid receptor gamma a	0.027
bmp1a	bone morphogenetic protein 1a	0.027
unc5b	unc-5 homolog B (C. elegans)	0.027	Mouse
igf1ra	insulin-like growth factor 1a receptor	0.027
mab21l2	mab-21-like 2	0.026
isl2a	islet2a	0.026
dlx5a	distal-less homeobox gene 5a	0.026
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.026
pkd2	polycystic kidney disease 2	0.026
sulf1	sulfatase 1	0.026
smad9	MAD homolog 9 (Drosophila)	0.025
antxr1	anthrax toxin receptor 1	0.025
lamb1a	laminin, beta 1a	0.025
gro2	groucho 2	0.025
lama5	laminin, alpha 5	0.024
plxna4	plexin A4	0.024
gpr126	G protein-coupled receptor 126	0.024
col14a1	collagen, type XIV, alpha 1	0.023
spry2	sprouty homolog 2	0.023
wnt3a	wingless-type MMTV integration site family, member 3A	0.023
isl1	islet1	0.022
otpa	orthopedia homolog a	0.022
ephb3a	eph receptor B3a	0.021
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.021
smad1	MAD homolog 1 (Drosophila)	0.021
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.021
emx2	empty spiracles homeobox 2	0.021
nrp2b	neuropilin 2b	0.021
sox1a	SRY-box containing gene 1a	0.021
LOC100000687	signal peptide, CUB and EGF-like domain-containing protein 3-like	0.021
igf1rb	insulin-like growth factor 1b receptor	0.020
dpysl2b	dihydropyrimidinase-like 2b	0.020
irx5a	iroquois homeobox protein 5a	0.020
gpc4	glypican 4	0.020
fgfr2	fibroblast growth factor receptor 2	0.020
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.020
mef2d	myocyte enhancer factor 2d	0.019
pitx3	paired-like homeodomain transcription factor 3	0.019
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.019
zbtb16a	zinc finger and BTB domain containing 16a	0.019
sfrp5	secreted frizzled-related protein 5	0.019
spaw	southpaw	0.019
flt4	fms-related tyrosine kinase 4	0.018
phox2a	paired-like homeobox 2a	0.018
dab1a	disabled homolog 1a (Drosophila)	0.018
gli3	GLI-Kruppel family member GLI3	0.018
nog2	noggin 2	0.017
hoxb1a	homeo box B1a	0.017
sall4	sal-like 4 (Drosophila)	0.017
hoxa3a	homeo box A3a	0.017
csnk1a1	casein kinase 1, alpha 1	0.017
nrarpb	notch-regulated ankyrin repeat protein b	0.017
tll1	tolloid-like 1	0.016
prdm5	PR domain containing 5	0.016
chd	chordin	0.016
nkx2.1a	NK2 homeobox 1a	0.016
pcdh19	protocadherin 19	0.016
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.015
plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.015
cd99l2	CD99 antigen-like 2	0.015
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.015
nog1	noggin 1	0.015
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.015
ttna	titin a	0.015
meis2.2	myeloid ecotropic viral integration site 2.2	0.015
egr2b	early growth response 2b	0.015
fbn2b	fibrillin 2b	0.014
pax6b	paired box gene 6b	0.014
hoxa2b	homeo box A2b	0.014
eya1	eyes absent homolog 1	0.014
fgf24	fibroblast growth factor 24	0.014
tcf12	transcription factor 12	0.014
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.014
ebf3	early B-cell factor 3	0.014
msxb	muscle segment homeobox B	0.014
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.014
zeb2a	zinc finger E-box binding homeobox 2a	0.014
eng1a	engrailed 1a	0.013
ptpra	protein tyrosine phosphatase, receptor type, A	0.013
frem1a	Fras1 related extracellular matrix 1a	0.013
cacna1da	calcium channel, voltage-dependent, L type, alpha 1D subunit, a	0.013
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.012
mapk6	mitogen-activated protein kinase 6	0.012
mxi1	max interacting protein	0.012
plxnb2a	plexin b2a	0.012
mecom	MDS1 and EVI1 complex locus	0.012
slit1b	slit homolog 1b (Drosophila)	0.012	Zebrafish
cdh5	cadherin 5	0.012
fgfr4	fibroblast growth factor receptor 4	0.012
col8a1a	collagen, type VIII, alpha 1a	0.012
spon2a	spondin 2a, extracellular matrix protein	0.011
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.011
nf1a	neurofibromin 1a	0.011
otpb	orthopedia homolog b	0.011
rx3	retinal homeobox gene 3	0.011
foxp1b	forkhead box P1b	0.011
pik3r2	phosphoinositide-3-kinase, regulatory subunit, polypeptide 2	0.011
prrx1a	paired related homeobox 1a	0.011
zic5	zic family member 5 (odd-paired homolog, Drosophila)	0.011
dab1b	disabled homolog 1b (Drosophila)	0.011
sh3gl1b	SH3-domain GRB2-like 1b	0.010
hoxa9b	homeo box A9b	0.010
hoxd3a	homeo box D3a	0.010
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.010
slc35b2	solute carrier family 35, member B2	0.010
lama2	laminin, alpha 2	0.010
foxg1a	forkhead box G1a	0.010