IMP

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Danio rerio

0 genes annotated in zebrafish

charcot marie tooth disease

DOID:10595

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "charcot marie tooth disease" (in gray)

Name	Description	Probability	Func Analog Organism
sema3d	semaphorin 3d	0.904
egr1	early growth response 1	0.344
hoxb1a	homeo box B1a	0.249
col6a3	collagen, type VI, alpha 3	0.224
irx4b	iroquois homeobox protein 4b	0.206
dcn	decorin	0.175
irx3b	iroquois homeobox protein 3b	0.155
tars	threonyl-tRNA synthetase	0.153
postn	periostin, osteoblast specific factor	0.137
col5a2l	collagen, type V, alpha 2-like	0.112
ca2	carbonic anhydrase II	0.110
hoxa2b	homeo box A2b	0.107
col1a1b	collagen, type I, alpha 1b	0.106
pdgfrl	platelet-derived growth factor receptor-like	0.105
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.102
egr2a	early growth response 2a	0.095	Human
pax3a	paired box gene 3a	0.078
sox10	SRY-box containing gene 10	0.077
hoxb2a	homeo box B2a	0.074
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.073
emilin1a	elastin microfibril interfacer 1a	0.072
aars	alanyl-tRNA synthetase	0.064	Human
col5a1	procollagen, type V, alpha 1	0.063
col12a1	collagen, type XII, alpha 1	0.063
eprs	glutamyl-prolyl-tRNA synthetase	0.063
cygb1	cytoglobin 1	0.062
cct5	chaperonin containing TCP1, subunit 5 (epsilon)	0.059
farsb	phenylalanyl-tRNA synthetase, beta subunit	0.057
lars	leucyl-tRNA synthetase	0.057
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.056
btg2	B-cell translocation gene 2	0.056
zwi	zwilling	0.053
irx7	iroquois homeobox protein 7	0.053
dusp2	dual specificity phosphatase 2	0.048
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.045
pa2g4b	proliferation-associated 2G4, b	0.044
egfl6	EGF-like-domain, multiple 6	0.044
ehd2	EH-domain containing 2	0.043
emp2	epithelial membrane protein 2	0.042
eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha	0.040
matn4	matrilin 4	0.039
col1a2	collagen, type I, alpha 2	0.039
esrrga	estrogen-related receptor gamma a	0.038
tgfbi	transforming growth factor, beta-induced	0.038
cct6a	chaperonin containing TCP1, subunit 6A (zeta 1)	0.037
eif3ja	eukaryotic translation initiation factor 3, subunit Ja	0.036
fgfr3	fibroblast growth factor receptor 3	0.033
hars	histidyl-tRNA synthetase	0.031
eif3b	eukaryotic translation initiation factor 3, subunit B	0.031
cd248a	CD248 molecule, endosialin a	0.030
kars	lysyl-tRNA synthetase	0.029
pax3b	paired box gene 3b	0.029
gabarapa	GABA(A) receptor-associated protein a	0.028
mmp2	matrix metalloproteinase 2	0.027
myod1	myogenic differentiation 1	0.026
sri	sorcin	0.026
lap3	leucine aminopeptidase 3	0.025
gmps	guanine monphosphate synthetase	0.025
timp2a	tissue inhibitor of metalloproteinase 2a	0.025
rxrbb	retinoid x receptor, beta b	0.024
sema3ab	semaphorin 3ab	0.024
hoxa3a	homeo box A3a	0.024
flncb	filamin C, gamma b (actin binding protein 280)	0.023
pax7b	paired box gene 7b	0.023
tbc1d15	TBC1 domain family, member 15	0.023
mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.023
egr2b	early growth response 2b	0.023	Human
si:ch1073-459j12.1	si:ch1073-459j12.1	0.023
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.022
hoxd3a	homeo box D3a	0.022
iars	isoleucyl-tRNA synthetase	0.022
sqstm1	sequestosome 1	0.022
s100v2	S100 calcium binding protein V2	0.022
si:ch211-212m21.5	si:ch211-212m21.5	0.021
nars	asparaginyl-tRNA synthetase	0.021
si:dkey-261h17.1	si:dkey-261h17.1	0.021
LOC100331484	hypothetical protein LOC100331484	0.021
zgc:100919	zgc:100919	0.021
dlst	dihydrolipoamide S-succinyltransferase	0.021
pax8	paired box gene 8	0.021
cdh17	cadherin 17, LI cadherin (liver-intestine)	0.020
zgc:73134	zgc:73134	0.020
myo15aa	myosin XVAa	0.020
eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	0.020
ctps	CTP synthase	0.020
vars	valyl-tRNA synthetase	0.019
sparc	secreted acidic cysteine rich glycoprotein	0.019
gspt1l	G1 to S phase transition 1, like	0.019
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.019
ehd1	EH-domain containing 1	0.019
prrx1a	paired related homeobox 1a	0.018
si:ch211-237l4.5	si:ch211-237l4.5	0.018
phb	prohibitin	0.018
drg2	developmentally regulated GTP binding protein 2	0.017
hoxb3a	homeo box B3a	0.017
nolc1	nucleolar and coiled-body phosphoprotein 1	0.017
atoh8	atonal homolog 8	0.017
rab5c	RAB5C, member RAS oncogene family	0.017
gtf2h4	general transcription factor IIH, polypeptide 4	0.017
pmp22b	peripheral myelin protein 22b	0.017	Human
unc45b	unc-45 homolog B (C. elegans)	0.017
loxl2b	lysyl oxidase-like 2b	0.017
cct3	chaperonin containing TCP1, subunit 3 (gamma)	0.017
elovl1b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b	0.016
gro1	groucho 1	0.016
fas	Fas (TNF receptor superfamily, member 6)	0.016
znf622	zinc finger protein 622	0.016
fn1b	fibronectin 1b	0.016
mettl11a	methyltransferase like 11A	0.016
zgc:63976	zgc:63976	0.016
im:6903943	im:6903943	0.016
myf6	myogenic factor 6	0.016
yars	tyrosyl-tRNA synthetase	0.015	Human
six2a	sine oculis-related homeobox 2a	0.015
smyd1b	SET and MYND domain containing 1b	0.015
bmp4	bone morphogenetic protein 4	0.015
atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.015
aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.015
plxnb2a	plexin b2a	0.015
efnb2a	ephrin B2a	0.015
ahnak	AHNAK nucleoprotein	0.015
h1fx	H1 histone family, member X	0.014
rest	RE1-silencing transcription factor	0.014
myl9	myosin, light polypeptide 9, regulatory	0.014
zgc:112052	zgc:112052	0.014
rpn2	ribophorin II	0.014
cars	cysteinyl-tRNA synthetase	0.014
actn2	actinin, alpha 2	0.014
zgc:100829	zgc:100829	0.013
gtpbp1	GTP binding protein 1	0.013
zfp36l1b	zinc finger protein 36, C3H type-like 1b	0.013
tpma	alpha-tropomyosin	0.013
zgc:100799	zgc:100799	0.013
si:dkey-151c10.1	si:dkey-151c10.1	0.013
lgals2a	lectin, galactoside-binding, soluble, 2a	0.013
zgc:66433	zgc:66433	0.013
etnk1	ethanolamine kinase 1	0.013
thbs4b	thrombospondin 4b	0.013
pdcd6	programmed cell death 6	0.012
impdh1b	inosine 5'-phosphate dehydrogenase 1b	0.012
podxl	podocalyxin-like	0.012
plk2b	polo-like kinase 2b (Drosophila)	0.012
tnnc1b	troponin C type 1b (slow)	0.012
ipo7	importin 7	0.012
ivns1abpa	influenza virus NS1A binding protein a	0.012
ppargc1al	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like	0.012
jam2a	junctional adhesion molecule 2a	0.012
cox4nb	cox4 neighbor	0.012
lrrc17	leucine rich repeat containing 17	0.012
chac1	ChaC, cation transport regulator-like 1	0.012
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.012
eif5a2	eukaryotic translation initiation factor 5A2	0.012
pdcd5	programmed cell death 5	0.012
seh1l	SEH1-like (S. cerevisiae)	0.012
ctgf	connective tissue growth factor	0.012
ppp1r14ab	protein phosphatase 1, regulatory (inhibitor) subunit 14Ab	0.012
rbbp9	retinoblastoma binding protein 9	0.012
arrdc2	arrestin domain containing 2	0.012
nudt5	nudix (nucleoside diphosphate linked moiety X)-type motif 5	0.012
clu	clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)	0.011
spry2	sprouty homolog 2	0.011
atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.011
id:ibd1152	id:ibd1152	0.011
cd63	Cd63 antigen	0.011
hsp90a.1	heat shock protein 90-alpha 1	0.011
ifrd2	interferon-related developmental regulator 2	0.011
sb:cb190	sb:cb190	0.011
atic	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	0.011
wu:fc14a10	wu:fc14a10	0.011
hnf1bb	HNF1 homeobox Bb	0.011
myoc	myocilin	0.011
snx4	sorting nexin 4	0.011
ak4	adenylate kinase 4	0.011
abce1	ATP-binding cassette, sub-family E (OABP), member 1	0.011
pde6c	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	0.011
dusp5	dual specificity phosphatase 5	0.011
prpf38a	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.011
pprc1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.011
eif2b4	eukaryotic translation initiation factor 2B, subunit 4 delta	0.011
ihha	Indian hedgehog homolog a	0.011
ndfip1	Nedd4 family interacting protein 1	0.011
inka1a	induced in neural crest by AP2, 1a	0.011
atp1a2a	ATPase, Na+/K+ transporting, alpha 2a polypeptide	0.011
wu:fc76b04	wu:fc76b04	0.011
ppdpfb	pancreatic progenitor cell differentiation and proliferation factor b	0.011
nab1a	NGFI-A binding protein 1a (EGR1 binding protein 1)	0.011
epha4a	eph receptor A4a	0.011
nog2	noggin 2	0.011
snx1	sorting nexin 1	0.011
usp5	ubiquitin specific protease 5	0.011
hspa9	heat shock protein 9	0.011
tpm1	tropomyosin 1 (alpha)	0.011
sb:cb592	sb:cb592	0.011
alx4b	aristaless-like homeobox 4b	0.011
junbl	jun B proto-oncogene, like	0.010
arpc1b	actin related protein 2/3 complex, subunit 1B	0.010
usp14	ubiquitin specific protease 14 (tRNA-guanine transglycosylase)	0.010
rab13	RAB13, member RAS oncogene family	0.010
alcamb	activated leukocyte cell adhesion molecule b	0.010
psat1	phosphoserine aminotransferase 1	0.010
pttg1ipb	pituitary tumor-transforming 1 interacting protein b	0.010
dpp3	dipeptidylpeptidase 3	0.010
efnb1	ephrin B1	0.010
col10a1	collagen, type X, alpha 1	0.010
immt	inner membrane protein, mitochondrial (mitofilin)	0.010
ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.010
slc39a3	solute carrier family 39 (zinc transporter), member 3	0.010
zgc:55683	zgc:55683	0.010
si:dkey-117i6.1	si:dkey-117i6.1	0.010
zgc:110460	zgc:110460	0.010