Process View
The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "dna alkylation"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
dnmt1 | DNA (cytosine-5-)-methyltransferase 1 | 0.351 | ||
eomesa | eomesodermin homolog a | 0.284 | ||
dnmt7 | DNA (cytosine-5-)-methyltransferase 7 | 0.253 | ||
whsc1 | Wolf-Hirschhorn syndrome candidate 1 | 0.235 | ||
dazl | daz-like gene | 0.207 | ||
marcksb | myristoylated alanine rich protein kinase C substrate b | 0.134 | ||
dnmt5 | DNA (cytosine-5-)-methyltransferase 5 | 0.117 | Human Zebrafish Mouse | |
sass6 | spindle assembly 6 homolog (C. elegans) | 0.111 | ||
org | oogenesis-related gene | 0.085 | ||
pola1 | polymerase (DNA directed), alpha 1 | 0.080 | ||
chek2 | CHK2 checkpoint homolog (S. pombe) | 0.079 | ||
mcm5 | MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) | 0.065 | ||
chaf1b | chromatin assembly factor 1, subunit B | 0.063 | ||
suv39h1a | suppressor of variegation 3-9 homolog 1a | 0.062 | ||
prim1 | primase polypeptide 1 | 0.060 | ||
lhx1b | LIM homeobox 1b | 0.059 | ||
ikzf1 | IKAROS family zinc finger 1 (Ikaros) | 0.058 | ||
nkx2.2a | NK2 transcription factor related 2a | 0.057 | ||
cbx2 | chromobox homolog 2 (Drosophila Pc class) | 0.055 | ||
smc3 | structural maintenance of chromosomes 3 | 0.054 | ||
pax6b | paired box gene 6b | 0.053 | ||
mos | v-mos Moloney murine sarcoma viral oncogene homolog | 0.047 | ||
usp1 | ubiquitin specific protease 1 | 0.045 | ||
hells | helicase, lymphoid-specific | 0.043 | Mouse | |
rif1 | RAP1 interacting factor homolog (yeast) | 0.043 | ||
ssrp1a | structure specific recognition protein 1a | 0.040 | ||
suv39h1b | suppressor of variegation 3-9 homolog 1b | 0.039 | ||
sox19b | SRY-box containing gene 19b | 0.038 | ||
nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.035 | ||
pax6a | paired box gene 6a | 0.035 | ||
setd8a | SET domain containing (lysine methyltransferase) 8a | 0.035 | ||
ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.035 | Mouse | |
ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.034 | ||
ung | uracil-DNA glycosylase | 0.034 | ||
setd2 | SET domain containing 2 | 0.034 | ||
gata2a | GATA-binding protein 2a | 0.034 | ||
tdrd1 | tudor domain containing 1 | 0.033 | ||
epb4.1l4 | erythrocyte protein band 4.1-like 4 | 0.033 | ||
nanos3 | nanos homolog 3 | 0.032 | ||
ahctf1 | AT hook containing transcription factor 1 | 0.030 | ||
orc1 | origin recognition complex, subunit 1 | 0.029 | ||
gro2 | groucho 2 | 0.029 | ||
drd2l | dopamine receptor D2 like | 0.029 | ||
notch1a | notch homolog 1a | 0.028 | ||
msh2 | mutS homolog 2 (E. coli) | 0.028 | ||
setdb1a | SET domain, bifurcated 1a | 0.027 | Fly | |
cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.027 | ||
tra2b | transformer 2 beta homolog (Drosophila) | 0.027 | ||
ehmt2 | euchromatic histone-lysine N-methyltransferase 2 | 0.026 | ||
chek1 | CHK1 checkpoint homolog (S. pombe) | 0.026 | ||
hoxb1a | homeo box B1a | 0.025 | ||
lcp1 | lymphocyte cytosolic plastin 1 | 0.025 | ||
LOC100151157 | similar to bin3, bicoid-interacting 3 | 0.024 | ||
hirip3 | HIRA interacting protein 3 | 0.024 | ||
foxe3 | forkhead box E3 | 0.024 | ||
otx1b | orthodenticle homolog 1b | 0.024 | ||
pds5b | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.023 | ||
fancd2 | Fanconi anemia, complementation group D2 | 0.023 | ||
irx4b | iroquois homeobox protein 4b | 0.022 | ||
otul | OTU like protein | 0.022 | ||
fanci | Fanconi anemia, complementation group I | 0.021 | ||
smc2 | structural maintenance of chromosomes 2 | 0.021 | ||
top2a | topoisomerase (DNA) II alpha | 0.020 | ||
pold1 | polymerase (DNA directed), delta 1, catalytic subunit | 0.020 | ||
nr2f1a | nuclear receptor subfamily 2, group F, member 1a | 0.020 | ||
prdm9 | PR domain containing 9 | 0.020 | ||
tbx5a | T-box 5a | 0.020 | ||
mcm4 | MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) | 0.019 | ||
atad5a | ATPase family, AAA domain containing 5a | 0.018 | ||
otpb | orthopedia homolog b | 0.018 | ||
whsc1l1 | Wolf-Hirschhorn syndrome candidate 1-like 1 | 0.018 | ||
zgc:110113 | zgc:110113 | 0.018 | ||
meis3 | myeloid ecotropic viral integration site 3 | 0.017 | ||
nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.017 | ||
anp32a | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.017 | ||
zgc:193933 | zgc:193933 | 0.017 | ||
elmo1 | engulfment and cell motility 1 (ced-12 homolog, C. elegans) | 0.016 | ||
wnt8a | wingless-type MMTV integration site family, member 8a | 0.016 | ||
bmi1b | B lymphoma Mo-MLV insertion region 1b | 0.016 | ||
znf711 | zinc finger protein 711 | 0.016 | ||
sinup | siaz-interacting nuclear protein | 0.015 | ||
ndr1 | nodal-related 1 | 0.015 | ||
gmnn | geminin, DNA replication inhibitor | 0.015 | ||
dnmt3 | DNA (cytosine-5-)-methyltransferase 3 | 0.015 | ||
pou3f3b | POU class 3 homeobox 3b | 0.015 | ||
her2 | hairy-related 2 | 0.015 | ||
hhex | hematopoietically expressed homeobox | 0.015 | ||
gro1 | groucho 1 | 0.014 | ||
drl | draculin | 0.014 | ||
esco2 | establishment of cohesion 1 homolog 2 | 0.014 | ||
hbbe1.1 | hemoglobin beta embryonic-1.1 | 0.014 | ||
wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.014 | ||
tbpl2 | TATA box binding protein like 2 | 0.014 | ||
lsm14b | LSM14B, SCD6 homolog B (S. cerevisiae) | 0.014 | ||
slc6a8 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 0.013 | ||
tcea1 | transcription elongation factor A (SII), 1 | 0.013 | ||
pwp2h | PWP2 periodic tryptophan protein homolog (yeast) | 0.013 | ||
rpa1 | replication protein A1 | 0.013 | ||
mll2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.013 | ||
epb41l5 | erythrocyte membrane protein band 4.1 like 5 | 0.012 | ||
pias4b | protein inhibitor of activated STAT, 4b | 0.012 | ||
buc | bucky ball | 0.012 | ||
scube2 | signal peptide, CUB domain, EGF-like 2 | 0.012 | ||
lrrc33 | leucine rich repeat containing 33 | 0.012 | ||
meis2.2 | myeloid ecotropic viral integration site 2.2 | 0.012 | ||
tgif1 | TGFB-induced factor homeobox 1 | 0.012 | ||
foxb1.2 | forkhead box B1.2 | 0.011 | ||
gmcl1 | germ cell-less homolog 1 (Drosophila) | 0.011 | ||
wnt1 | wingless-type MMTV integration site family, member 1 | 0.011 | ||
sulf2 | sulfatase 2 | 0.011 | ||
im:6907928 | im:6907928 | 0.011 | ||
krcp | kelch repeat-containing protein | 0.011 | ||
sephs1 | selenophosphate synthetase 1 | 0.011 | ||
slbp | stem-loop binding protein | 0.011 | ||
dtl | denticleless homolog (Drosophila) | 0.010 | ||
rspo3 | R-spondin 3 homolog (Xenopus laevis) | 0.010 | ||
mll4a | myeloid/lymphoid or mixed-lineage leukemia 4a | 0.010 | ||
zorba | Orb/CPEB-related RNA-binding protein | 0.010 |