IMP
Process View
double strand break repair via nonhomologous end joining
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "double strand break repair via nonhomologous end joining"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| rrm1 | ribonucleotide reductase M1 polypeptide | 0.630 | ||
| slbp | stem-loop binding protein | 0.581 | ||
| mybl2 | myeloblastosis oncogene-like 2 | 0.209 | ||
| msh2 | mutS homolog 2 (E. coli) | 0.132 | ||
| ipo9 | importin 9 | 0.116 | ||
| hells | helicase, lymphoid-specific | 0.105 | ||
| pola1 | polymerase (DNA directed), alpha 1 | 0.097 | Human | |
| hat1 | histone acetyltransferase 1 | 0.093 | ||
| mcm4 | MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) | 0.092 | ||
| wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.090 | ||
| mcm5 | MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) | 0.087 | ||
| LOC100537814 | kinetochore-associated protein 1-like | 0.085 | ||
| dnmt1 | DNA (cytosine-5-)-methyltransferase 1 | 0.077 | ||
| anp32b | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.075 | ||
| nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.061 | ||
| rfc1 | replication factor C (activator 1) 1 | 0.060 | ||
| ppm1g | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 0.058 | ||
| fen1 | flap structure-specific endonuclease 1 | 0.057 | Yeast | |
| mcmbp | minichromosome maintenance complex binding protein | 0.048 | ||
| prim1 | primase polypeptide 1 | 0.047 | ||
| zgc:110113 | zgc:110113 | 0.047 | ||
| rbb4 | retinoblastoma binding protein 4 | 0.047 | ||
| rpa1 | replication protein A1 | 0.045 | ||
| pds5b | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.038 | ||
| ubr7 | ubiquitin protein ligase E3 component n-recognin 7 | 0.036 | ||
| zgc:92648 | zgc:92648 | 0.036 | ||
| dut | dUTP pyrophosphatase | 0.034 | ||
| rfc5 | replication factor C (activator 1) 5 | 0.033 | ||
| rbb4l | retinoblastoma binding protein 4, like | 0.032 | ||
| pcna | proliferating cell nuclear antigen | 0.032 | ||
| LOC563669 | cohesin subunit SA-3-like | 0.032 | ||
| zgc:110540 | zgc:110540 | 0.031 | ||
| whsc1 | Wolf-Hirschhorn syndrome candidate 1 | 0.028 | Mouse | |
| hirip3 | HIRA interacting protein 3 | 0.027 | ||
| cdk2 | cyclin-dependent kinase 2 | 0.022 | Yeast | |
| zgc:113210 | zgc:113210 | 0.021 | ||
| asf1bb | ASF1 anti-silencing function 1 homolog Bb | 0.021 | ||
| acvr2a | activin receptor IIa | 0.020 | ||
| orc6 | origin recognition complex, subunit 6 | 0.020 | ||
| anp32a | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.018 | ||
| mbd3b | methyl-CpG binding domain protein 3b | 0.018 | ||
| usp1 | ubiquitin specific protease 1 | 0.018 | ||
| sae1 | SUMO1 activating enzyme subunit 1 | 0.018 | ||
| rpa3 | replication protein A3 | 0.017 | ||
| ptpn11a | protein tyrosine phosphatase, non-receptor type 11, a | 0.016 | ||
| si:ch1073-351m12.1 | si:ch1073-351m12.1 | 0.015 | ||
| mcm7 | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 0.015 | ||
| msh6 | mutS homolog 6 (E. coli) | 0.014 | ||
| ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.014 | ||
| rrm2 | ribonucleotide reductase M2 polypeptide | 0.013 | ||
| wnt8a | wingless-type MMTV integration site family, member 8a | 0.013 | ||
| myst2 | MYST histone acetyltransferase 2 | 0.013 | ||
| cpsf2 | cleavage and polyadenylation specific factor 2 | 0.013 | ||
| ncapd2 | non-SMC condensin I complex, subunit D2 | 0.012 | ||
| parp2 | poly (ADP-ribose) polymerase family, member 2 | 0.012 | ||
| snrpa | small nuclear ribonucleoprotein polypeptide A | 0.011 | ||
| ccne2 | cyclin E2 | 0.011 | ||
| wu:fc85c01 | wu:fc85c01 | 0.011 | ||
| pola2 | polymerase (DNA directed), alpha 2 | 0.011 | ||
| zgc:113183 | zgc:113183 | 0.010 | ||
| zgc:100817 | zgc:100817 | 0.010 | ||
| elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.010 |