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Danio rerio

20 genes annotated in zebrafish

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regulation of cell fate specification

GO:0042659

Any process that mediates the adoption of a specific fate by a cell.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cell fate specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cell fate specification" (in gray)

Name	Description	Probability	Func Analog Organism
chd	chordin	0.970
vent	ventral expressed homeobox	0.841
fgfr1a	fibroblast growth factor receptor 1a	0.795
gata3	GATA-binding protein 3	0.742
bmp4	bone morphogenetic protein 4	0.648
bmp2b	bone morphogenetic protein 2b	0.596
sox9b	SRY-box containing gene 9b	0.544	Zebrafish
hoxb2a	homeo box B2a	0.491
sox1a	SRY-box containing gene 1a	0.465	Zebrafish
vsx2	visual system homeobox 2	0.457	Zebrafish
msxc	muscle segment homeobox C	0.453	Fly
hmx4	H6 family homeobox 4	0.416	Worm
tbx1	T-box 1	0.384
dusp6	dual specificity phosphatase 6	0.373
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.360
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.342	Worm
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.327
eya1	eyes absent homolog 1	0.327	Fly
dharma	dharma	0.325
dkk1b	dickkopf 1b	0.305	Mouse
wnt1	wingless-type MMTV integration site family, member 1	0.299	Fly
atoh1a	atonal homolog 1a	0.293
foxg1a	forkhead box G1a	0.263
pcdh8	protocadherin 8	0.262
jag1a	jagged 1a	0.238
flh	floating head	0.235
nkx2.2a	NK2 transcription factor related 2a	0.232
notch2	notch homolog 2	0.219	Zebrafish Fly
jag2	jagged 2	0.213
six4b	sine oculis homeobox homolog 4b	0.212
pitx3	paired-like homeodomain transcription factor 3	0.208
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.208
meis3	myeloid ecotropic viral integration site 3	0.205
gbx2	gastrulation brain homeo box 2	0.183
dlb	deltaB	0.182
ndr2	nodal-related 2	0.181
evx1	even-skipped homeobox 1	0.166	Zebrafish
hoxa11a	homeo box A11a	0.162
hmx3	homeo box (H6 family) 3	0.149	Worm
alas2	aminolevulinate, delta-, synthetase 2	0.147
fgf3	fibroblast growth factor 3	0.143
hoxd11a	homeo box D11a	0.141
hoxb5a	homeo box B5a	0.140
vsx1	visual system homeobox 1 homolog, chx10-like	0.136
tcf7l1b	transcription factor 7-like 1b (T-cell specific, HMG-box)	0.116	Worm
neo1	neogenin 1	0.110
otpb	orthopedia homolog b	0.109
hhip	hedgehog interacting protein	0.106
fgf10a	fibroblast growth factor 10a	0.101
hoxa9a	homeo box A9a	0.101
dld	deltaD	0.100
tbx6	T-box gene 6	0.096
twist3	twist3	0.095
col14a1	collagen, type XIV, alpha 1	0.095
gata4	GATA-binding protein 4	0.094
notch1a	notch homolog 1a	0.092
spry4	sprouty (Drosophila) homolog 4	0.091
gli1	GLI-Kruppel family member 1	0.091
hoxb8a	homeo box B8a	0.090
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.089
lhx1a	LIM homeobox 1a	0.088
gro2	groucho 2	0.087
rarab	retinoic acid receptor, alpha b	0.086
ndr1	nodal-related 1	0.083
hoxa10b	homeo box A10b	0.082
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.081
wnt8b	wingless-type MMTV integration site family, member 8b	0.081
notch3	notch homolog 3	0.080	Zebrafish Fly
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.076
rest	RE1-silencing transcription factor	0.073
acvr1b	activin A receptor, type IB	0.071
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.069
tp73	tumor protein p73	0.068
wt1a	wilms tumor 1a	0.067
sox32	SRY-box containing gene 32	0.066
boc	brother of CDO	0.066
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.066
tp63	tumor protein p63	0.065
pax8	paired box gene 8	0.065	Fly
rorb	RAR-related orphan receptor B	0.062
lft1	lefty1	0.061
zgc:136773	zgc:136773	0.059
her5	hairy-related 5	0.058
mespa	mesoderm posterior a	0.058	Mouse
tbx2b	T-box 2b	0.058
cdh2	cadherin 2, neuronal	0.057
dlx5a	distal-less homeobox gene 5a	0.056
tll1	tolloid-like 1	0.056
lhx1b	LIM homeobox 1b	0.056
evx2	even-skipped homeobox 2	0.055	Zebrafish
notum3	notum 3	0.055
spaw	southpaw	0.055
neurod4	neurogenic differentiation 4	0.054
fzd5	frizzled homolog 5	0.054
sox11b	SRY-box containing gene 11b	0.053
wnt10a	wingless-type MMTV integration site family, member 10a	0.053
runx2b	runt-related transcription factor 2b	0.052
eng1a	engrailed 1a	0.052
wnt3	wingless-type MMTV integration site family, member 3	0.051
tshb	thyroid stimulating hormone, beta subunit	0.051
ephb4b	eph receptor B4b	0.051
rx2	retinal homeobox gene 2	0.051
her7	hairy and enhancer of split related-7	0.051
vax2	ventral anterior homeobox 2	0.051
igf1rb	insulin-like growth factor 1b receptor	0.051
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.050
il17rd	interleukin 17 receptor D	0.050
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.050
wnt4a	wingless-type MMTV integration site family, member 4a	0.049
epha4b	eph receptor A4b	0.048
egr2a	early growth response 2a	0.048
ryr2b	ryanodine receptor 2b (cardiac)	0.048
dcc	deleted in colorectal carcinoma	0.047
gdf6b	growth differentiation factor 6b	0.047	Zebrafish
osr2	odd-skipped related 2 (Drosophila)	0.047
pcdh18a	protocadherin 18a	0.046
cherp	calcium homeostasis endoplasmic reticulum protein	0.046
pou2f1a	POU class 2 homeobox 1a	0.046	Zebrafish
foxd5	forkhead box D5	0.046
epha7	eph receptor A7	0.045
hoxd10a	homeo box D10a	0.043
nog2	noggin 2	0.043	Zebrafish
dlx2a	distal-less homeobox gene 2a	0.042
og9x	OG9 homeobox gene	0.042
etv2	ets variant gene 2	0.041
tbx5a	T-box 5a	0.041
msxb	muscle segment homeobox B	0.041	Fly
hoxb5b	homeo box B5b	0.041
robo1	roundabout homolog 1	0.041
phc2	polyhomeotic-like 2 (Drosophila)	0.041
fgf24	fibroblast growth factor 24	0.040
hoxb1b	homeo box B1b	0.040
fgf17	fibroblast growth factor 17	0.040
waca	WW domain containing adaptor with coiled-coil a	0.040
tbx20	T-box 20	0.039
oep	one-eyed pinhead	0.038
thoc5	THO complex 5	0.037
cdh1	cadherin 1, epithelial	0.037
sall4	sal-like 4 (Drosophila)	0.037
fgf4	fibroblast growth factor 4	0.037
hapln3	hyaluronan and proteoglycan link protein 3	0.037
acvr2b	activin receptor IIb	0.036
her1	hairy-related 1	0.036
wif1	wnt inhibitory factor 1	0.035
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.035
ved	ventrally expressed dharma/bozozok antagonist	0.035
sfrp1a	secreted frizzled-related protein 1a	0.035
foxi1	forkhead box I1	0.035
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.035
lef1	lymphocyte enhancer binding factor 1	0.035	Worm
fgf8a	fibroblast growth factor 8 a	0.034
pax2b	paired box gene 2b	0.034	Fly
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.034
zgc:153997	zgc:153997	0.033
irf2bp2a	interferon regulatory factor 2 binding protein 2a	0.033
mafl	v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L	0.033
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.032
irx3b	iroquois homeobox protein 3b	0.032
odz4	odd Oz/ten-m homolog 4	0.032
hoxa2b	homeo box A2b	0.032
lhx2b	LIM homeobox 2b	0.032
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.031
flt4	fms-related tyrosine kinase 4	0.031
six4a	sine oculis homeobox homolog 4a	0.031
otx5	orthodenticle homolog 5	0.031
pld1a	phospholipase D1a	0.031
irx4b	iroquois homeobox protein 4b	0.030
btg2	B-cell translocation gene 2	0.030
blf	bloody fingers	0.030
foxa3	forkhead box A3	0.030
hoxa4a	homeo box A4a	0.030
tbx16	T-box gene 16	0.030
efnb3b	ephrin B3b	0.030
lfng	lunatic fringe homolog	0.030
fibin	fin bud initiation factor	0.029
her12	hairy-related 12	0.029
aplnrb	apelin receptor b	0.029
wls	wntless homolog (Drosophila)	0.029
dacha	dachshund a	0.028
fgf8b	fibroblast growth factor 8 b	0.028	Zebrafish
shha	sonic hedgehog a	0.028
notch1b	notch homolog 1b	0.028	Zebrafish Fly
atoh1b	atonal homolog 1b	0.028
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.028
ogn	osteoglycin	0.028
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.027
znf703	zinc finger protein 703	0.027
hmx2	H6 family homeobox 2	0.027
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.027
hnf1ba	HNF1 homeobox Ba	0.027	Mouse
snai1b	snail homolog 1b (Drosophila)	0.027
zfand5a	zinc finger, AN1-type domain 5a	0.026
hoxd3a	homeo box D3a	0.026	Zebrafish
foxb1.2	forkhead box B1.2	0.026
mespb	mesoderm posterior b	0.025	Mouse
tbx4	T-box 4	0.025
mapk4	mitogen-activated protein kinase 4	0.025
cdx4	caudal type homeo box transcription factor 4	0.024
etv5b	ets variant 5b	0.024
kif7	kinesin family member 7	0.024
irx3a	iroquois homeobox protein 3a	0.024
gdf6a	growth differentiation factor 6a	0.024	Zebrafish
midn	midnolin	0.024
frem2a	Fras1 related extracellular matrix protein 2a	0.024
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.024
ptf1a	pancreas specific transcription factor, 1a	0.024
atf3	activating transcription factor 3	0.024
vax1	ventral anterior homeobox 1	0.023
cryaba	crystallin, alpha B, a	0.023
foxe3	forkhead box E3	0.023
wnt11r	wingless-type MMTV integration site family, member 11, related	0.023
hoxc8a	homeo box C8a	0.023
vcana	versican a	0.023
e2f4	E2F transcription factor 4	0.023
fzd7a	frizzled homolog 7a	0.022
jag1b	jagged 1b	0.022
junbl	jun B proto-oncogene, like	0.022
eng1b	engrailed 1b	0.022
otx1a	orthodenticle homolog 1a	0.021
hoxc13a	homeo box C13a	0.021
tfap2a	transcription factor AP-2 alpha	0.021
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.021
gata2a	GATA-binding protein 2a	0.021
hoxb7a	homeo box B7a	0.020
msxd	muscle segment homeobox D	0.020
sox19b	SRY-box containing gene 19b	0.020	Zebrafish
gatad2a	GATA zinc finger domain containing 2A	0.020
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.020
foxh1	forkhead box H1	0.020
pnx	posterior neuron-specific homeobox	0.020
sim1a	single-minded homolog 1a (Drosophila)	0.020
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.020
pou3f3b	POU class 3 homeobox 3b	0.020
rtn1a	reticulon 1a	0.019
etv5a	ets variant 5a	0.019
raraa	retinoic acid receptor, alpha a	0.019
hoxd12a	homeo box D12a	0.019	Fly
mab21l2	mab-21-like 2	0.019
metrnl	meteorin, glial cell differentiation regulator-like	0.019
krt4	keratin 4	0.019
rasl11b	RAS-like, family 11, member B	0.019
runx2a	runt-related transcription factor 2a	0.019
socs3a	suppressor of cytokine signaling 3a	0.019
ntf7	neurotrophin 7	0.018
fgf18a	fibroblast growth factor 18a	0.018
shroom4	shroom family member 4	0.018
tmem2	transmembrane protein 2	0.018
efnb2a	ephrin B2a	0.018
pcdh10b	protocadherin 10b	0.018
wnt5b	wingless-type MMTV integration site family, member 5b	0.018
bmp7a	bone morphogenetic protein 7a	0.018
coro1b	coronin, actin binding protein, 1B	0.017
sox21a	SRY-box containing gene 21a	0.017
gro1	groucho 1	0.017
mecom	MDS1 and EVI1 complex locus	0.017
zgc:193933	zgc:193933	0.017
wu:fb76c12	wu:fb76c12	0.017
tdh	L-threonine dehydrogenase	0.017
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.017
mxtx2	mix-type homeobox gene 2	0.017
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.017
nhsl1a	NHS-like 1a	0.017
msgn1	mesogenin 1	0.017
tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.017
sall1a	sal-like 1a (Drosophila)	0.017
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.016
zic6	zic family member 6	0.016
ptch1	patched 1	0.016
irx2a	iroquois homeobox protein 2, a	0.016
gadd45ab	growth arrest and DNA-damage-inducible, alpha, b	0.016
gsc	goosecoid	0.016
fgfr2	fibroblast growth factor receptor 2	0.016	Zebrafish
snai3	snail homolog 3	0.016
cyt1	type I cytokeratin, enveloping layer	0.016
hoxd13a	homeo box D13a	0.015
irx1b	iroquois homeobox protein 1, b	0.015
si:ch211-173o4.2	si:ch211-173o4.2	0.015
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.015
dlx4b	distal-less homeobox gene 4b	0.015
hoxd4a	homeo box D4a	0.015
sox4b	SRY-box containing gene 4b	0.015
eng2b	engrailed 2b	0.015
vangl2	vang-like 2 (van gogh, Drosophila)	0.015
ef1	ETS-related factor1	0.015
chd7	chromodomain helicase DNA binding protein 7	0.015
fosl2	fos-like antigen 2	0.015
bon	bonnie and clyde	0.015
heyl	hairy/enhancer-of-split related with YRPW motif-like	0.014
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.014
sox3	SRY-box containing gene 3	0.014	Zebrafish
tax1bp1b	Tax1 (human T-cell leukemia virus type I) binding protein 1b	0.014
suv39h1a	suppressor of variegation 3-9 homolog 1a	0.014
fgf20a	fibroblast growth factor 20a	0.014
klf4a	Kruppel-like transcription factor 4a	0.014
junb	jun B proto-oncogene	0.014
kitb	kit receptor b	0.014
LOC100000500	sclerostin-like	0.014
csrnp1a	cysteine-serine-rich nuclear protein 1a	0.014
slc17a6a	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6a	0.014
pou5f1	POU domain, class 5, transcription factor 1	0.014
spry2	sprouty homolog 2	0.014
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.014
axin1	axin 1	0.014	Worm
insb	preproinsulin b	0.014
atp1a1a.5	ATPase, Na+/K+ transporting, alpha 1a.5 polypeptide	0.014
fgf22	fibroblast growth factor 22	0.014
twsg1b	twisted gastrulation homolog 1b (Drosophila)	0.014
epb4.1l4	erythrocyte protein band 4.1-like 4	0.014
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.013	Fly
egr2b	early growth response 2b	0.013
meis2.1	myeloid ecotropic viral integration site 2.1	0.013
rgs4	regulator of G-protein signalling 4	0.013
btbd6a	BTB (POZ) domain containing 6a	0.013
irx5b	iroquois homeobox protein 5b	0.013
zgc:66100	zgc:66100	0.013
ifnphi1	interferon phi 1	0.013
nrg2b	neuregulin 2b	0.013
klf2a	Kruppel-like factor 2a	0.013
bactin2	bactin2	0.013
lhx3	LIM homeobox 3	0.013
otomp	otolith matrix protein	0.013
rhoub	ras homolog gene family, member Ub	0.013
fras1	Fraser syndrome 1	0.013
fzd8b	frizzled homolog 8b	0.013
irx4a	iroquois homeobox protein 4a	0.013
stk11	serine/threonine kinase 11	0.013
tnfsf10l2	tumor necrosis factor (ligand) superfamily, member 10 like 2	0.013
cbx2	chromobox homolog 2 (Drosophila Pc class)	0.013
dusp2	dual specificity phosphatase 2	0.013	Zebrafish
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.013
srf	serum response factor	0.013
plk3	polo-like kinase 3 (Drosophila)	0.013
atoh7	atonal homolog 7	0.013
hoxb4a	homeo box B4a	0.013
tmpoa	thymopoietin a	0.013
tsc22d3	TSC22 domain family, member 3	0.013
si:dkeyp-66d7.2	si:dkeyp-66d7.2	0.013
irf6	interferon regulatory factor 6	0.013
nanos3	nanos homolog 3	0.012
tyr	tyrosinase	0.012
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.012
sox9a	SRY-box containing gene 9a	0.012	Zebrafish
rfng	radical fringe homolog (Drosophila)	0.012
mpped2	metallophosphoesterase domain containing 2	0.012
zfp36l1b	zinc finger protein 36, C3H type-like 1b	0.012
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.012
gbx1	gastrulation brain homeobox 1	0.012
dlc	deltaC	0.012
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.012
hbbe3	hemoglobin beta embryonic-3	0.012
ryk	receptor-like tyrosine kinase	0.012
fgf16	fibroblast growth factor 16	0.012
plagl2	pleiomorphic adenoma gene-like 2	0.012
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.012
ing4	inhibitor of growth family, member 4	0.012
hoxc4a	homeo box C4a	0.012
lhx5	LIM homeobox 5	0.012
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.012
ift122	intraflagellar transport 122 homolog (Chlamydomonas)	0.012
ihha	Indian hedgehog homolog a	0.012
myo6b	myosin VIb	0.012
arhgap11a	Rho GTPase activating protein 11A	0.012
zgc:56064	zgc:56064	0.011
emp2	epithelial membrane protein 2	0.011
gli2b	GLI-Kruppel family member GLI2b	0.011
bambib	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b	0.011
zgc:136874	zgc:136874	0.011
rx3	retinal homeobox gene 3	0.011
coe2	coe2	0.011
ripply1	ripply1	0.011
alcamb	activated leukocyte cell adhesion molecule b	0.011
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.011
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.011
twist1b	twist1b	0.011
emx3	empty spiracles homeobox 3	0.011
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.011
slit3	slit (Drosophila) homolog 3	0.011
epha2	eph receptor A2	0.011
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.011
wt1b	wilms tumor 1b	0.011
irx1a	iroquois homeobox protein 1, a	0.011
spata4	spermatogenesis associated 4	0.011
grhl2a	grainyhead-like 2a (Drosophila)	0.011
uts2a	urotensin 2, alpha	0.011
wnt8a	wingless-type MMTV integration site family, member 8a	0.011
csnk1g2a	casein kinase 1, gamma 2a	0.011
irx7	iroquois homeobox protein 7	0.011
dsc2l	desmocollin 2 like	0.011
hs6st1a	heparan sulfate 6-O-sulfotransferase 1a	0.011
myo7aa	myosin VIIAa	0.011
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.011
drd2b	dopamine receptor D2b	0.011
drd2l	dopamine receptor D2 like	0.011
si:dkeyp-113d7.1	si:dkeyp-113d7.1	0.011
admp	anti-dorsalizing morphogenic protein	0.011	Zebrafish
gli3	GLI-Kruppel family member GLI3	0.011
nt5c2l1	5'-nucleotidase, cytosolic II, like 1	0.011
myhc4	myosin heavy chain 4	0.011
sp9	sp9 transcription factor	0.011
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.011
nr4a1	nuclear receptor subfamily 4, group A, member 1	0.011
socs3b	suppressor of cytokine signaling 3b	0.011
ctnnd2a	catenin (cadherin-associated protein), delta 2a	0.010
zgc:92851	zgc:92851	0.010
mecp2	methyl CpG binding protein 2	0.010
sh2d3cb	SH2 domain containing 3Cb	0.010
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.010
bmp2a	bone morphogenetic protein 2a	0.010	Zebrafish
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.010
im:7138239	im:7138239	0.010
prtga	protogenin homolog a (Gallus gallus)	0.010
zgc:66433	zgc:66433	0.010
zgc:123170	zgc:123170	0.010
foxd3	forkhead box D3	0.010
zgc:112397	zgc:112397	0.010
ripply2	ripply2	0.010
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.010
slc38a2	solute carrier family 38, member 2	0.010
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.010
brd4	bromodomain containing 4	0.010