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Process View

Danio rerio

6 genes annotated in zebrafish

mitotic sister chromatid segregation

The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitotic sister chromatid segregation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitotic sister chromatid segregation" (in gray)

Name	Description	Probability	Func Analog Organism
kif23	kinesin family member 23	0.686
hoxa10b	homeo box A10b	0.680	Fly
ncapd2	non-SMC condensin I complex, subunit D2	0.627
cep55l	centrosomal protein 55 like	0.526
ccnb1	cyclin B1	0.503	Human Fly
hoxd10a	homeo box D10a	0.451	Fly
hoxa9b	homeo box A9b	0.434	Fly
ccnb2	cyclin B2	0.419	Fly
smc4	structural maintenance of chromosomes 4	0.373	Human Yeast Worm
ncapg	non-SMC condensin I complex, subunit G	0.354
hoxc9a	homeo box C9a	0.336
tacc3	transforming, acidic coiled-coil containing protein 3	0.322
hoxd11a	homeo box D11a	0.270
aurkb	aurora kinase B	0.243
hoxd9a	homeo box D9a	0.220	Fly
zgc:110540	zgc:110540	0.196
smc3	structural maintenance of chromosomes 3	0.158
smc2	structural maintenance of chromosomes 2	0.153	Human Yeast Worm Fly
ncaph	non-SMC condensin I complex, subunit H	0.153
dnd	dead end	0.130
buc	bucky ball	0.120
ccna2	cyclin A2	0.111
si:ch211-244o22.2	si:ch211-244o22.2	0.106
kdm5c	lysine (K)-specific demethylase 5C	0.103
chaf1b	chromatin assembly factor 1, subunit B	0.101
nanos3	nanos homolog 3	0.100
psmc6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.099
mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.096	Human Mouse Worm
plk1	polo-like kinase 1 (Drosophila)	0.095	Human
dtl	denticleless homolog (Drosophila)	0.088
sass6	spindle assembly 6 homolog (C. elegans)	0.085
cdt1	chromatin licensing and DNA replication factor 1	0.083	Fly
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.077
hoxa11b	homeo box A11b	0.077
hoxb10a	homeo box B10a	0.077	Fly
melk	maternal embryonic leucine zipper kinase	0.074
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.073
polr2b	polymerase (RNA) II (DNA directed) polypeptide B	0.072
usp5	ubiquitin specific protease 5	0.071
stil	TAL1 (SCL) interrupting locus	0.066
ttk	ttk protein kinase	0.065	Yeast
hoxc10a	homeo box C10a and homeobox protein Hox-C10a-like	0.065
zgc:55448	zgc:55448	0.062
esco2	establishment of cohesion 1 homolog 2	0.061
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.055
aurka	aurora kinase A	0.055
suv39h1b	suppressor of variegation 3-9 homolog 1b	0.052
kif11	kinesin family member 11	0.051
pbrm1l	polybromo 1, like	0.050
ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.047	Worm
cdca8	cell division cycle associated 8	0.046	Human
gins3	GINS complex subunit 3	0.046
dnmt5	DNA (cytosine-5-)-methyltransferase 5	0.045
zgc:193933	zgc:193933	0.045
dazl	daz-like gene	0.044
krcp	kelch repeat-containing protein	0.044
psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.042
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.041	Worm
psmb4	proteasome (prosome, macropain) subunit, beta type, 4	0.040
zgc:153910	zgc:153910	0.040
si:ch211-215h6.2	si:ch211-215h6.2	0.039
eif1axb	eukaryotic translation initiation factor 1A, X-linked, b	0.039
cdc20	cell division cycle 20 homolog	0.039	Yeast Worm Fly
bag6	BCL2-associated athanogene 6	0.038
dnmt1	DNA (cytosine-5-)-methyltransferase 1	0.038
wu:fi04f09	wu:fi04f09	0.038
plk4	polo-like kinase 4 (Drosophila)	0.037
skp2	S-phase kinase-associated protein 2 (p45)	0.037
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.036
zgc:153369	zgc:153369	0.033
zorba	Orb/CPEB-related RNA-binding protein	0.032
hoxd4a	homeo box D4a	0.032
pak2b	p21 (CDKN1A)-activated kinase 2b	0.031
zgc:56200	zgc:56200	0.031
prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.030
si:dkey-9k8.1	si:dkey-9k8.1	0.030
pou5f1	POU domain, class 5, transcription factor 1	0.029
si:ch211-278b8.3	si:ch211-278b8.3	0.029
dnmt3	DNA (cytosine-5-)-methyltransferase 3	0.028
shcbp1	SHC SH2-domain binding protein 1	0.028
hoxd12a	homeo box D12a	0.027
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.027
nusap1	nucleolar and spindle associated protein 1	0.027	Human
eif4e1b	eukaryotic translation initiation factor 4e 1b	0.026	Fly
lsm14b	LSM14B, SCD6 homolog B (S. cerevisiae)	0.026
nolc1	nucleolar and coiled-body phosphoprotein 1	0.026
hoxd13a	homeo box D13a	0.025
cand1	cullin-associated and neddylation-dissociated 1	0.025
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.025
si:ch211-51m24.3	si:ch211-51m24.3	0.025
zgc:92775	zgc:92775	0.024
birc5a	baculoviral IAP repeat-containing 5a	0.024
rtkn2	rhotekin 2	0.024
psmc4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.023
sinup	siaz-interacting nuclear protein	0.023
psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.023
tardbpl	TAR DNA binding protein, like	0.023
hoxc6b	homeo box C6b	0.023
skiv2l2	superkiller viralicidic activity 2-like 2	0.023
org	oogenesis-related gene	0.023
psma6a	proteasome (prosome, macropain) subunit, alpha type, 6a	0.022
zgc:174506	zgc:174506	0.022
slbp	stem-loop binding protein	0.022	Worm Fly
zgc:110434	zgc:110434	0.022
cald1	caldesmon 1	0.022
ercc2	excision repair cross-complementing rodent repair deficiency, complementation group 2	0.022
zgc:136263	zgc:136263	0.022
ube2v2	ubiquitin-conjugating enzyme E2 variant 2	0.022
wdhd1	WD repeat and HMG-box DNA binding protein 1	0.021
prdm1a	PR domain containing 1a, with ZNF domain	0.021
zgc:152925	zgc:152925	0.020
LOC100151531	zinc finger protein Gfi-1b-like	0.020
psmd1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.019
rnf40	ring finger protein 40	0.019
plxnb2b	plexin b2b	0.019
zgc:92661	zgc:92661	0.019
hoxc11a	homeo box C11a	0.019
kidins220b	kinase D-interacting substrate of 220b	0.019
wipi2	WD repeat domain, phosphoinositide interacting 2	0.018
mos	v-mos Moloney murine sarcoma viral oncogene homolog	0.018
psmb2	proteasome (prosome, macropain) subunit, beta type, 2	0.018
naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.018
sf3a1	splicing factor 3a, subunit 1	0.018
capn2b	calpain 2, (m/II) large subunit b	0.018
smc1al	structural maintenance of chromosomes 1A, like	0.018
zc3h13	zinc finger CCCH-type containing 13	0.018
vasa	vasa homolog	0.018	Fly
snrpe	small nuclear ribonucleoprotein polypeptide E	0.018
sf3b5	splicing factor 3b, subunit 5	0.018
zgc:112980	zgc:112980	0.017
tubgcp5	tubulin, gamma complex associated protein 5	0.017
eif3ja	eukaryotic translation initiation factor 3, subunit Ja	0.017
insb	preproinsulin b	0.017
si:ch211-197n10.2	si:ch211-197n10.2	0.017
zff9	zinc finger protein 9	0.017
hsbp1	heat shock factor binding protein 1	0.017
psmb6	proteasome (prosome, macropain) subunit, beta type, 6	0.016
zgc:110113	zgc:110113	0.016
rad21	RAD21 homolog (S. pombe)	0.016
psma8	proteasome (prosome, macropain) subunit, alpha type, 8	0.016
cul1a	cullin 1a	0.016
gga1	golgi associated, gamma adaptin ear containing, ARF binding protein 1	0.016
e2f7	E2F transcription factor 7	0.016
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.016
tdp2b	tyrosyl-DNA phosphodiesterase 2b	0.016
nedd1	neural precursor cell expressed, developmentally down-regulated 1	0.015
prps1b	phosphoribosyl pyrophosphate synthetase 1B	0.015
cdc23	CDC23 (cell division cycle 23, yeast, homolog)	0.015	Human
shfm1	split hand/foot malformation (ectrodactyly) type 1	0.015
tubg1	tubulin, gamma 1	0.015	Worm
ck2b	casein kinase 2 beta	0.015
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.015
srsf1a	serine/arginine-rich splicing factor 1a	0.015
cul3a	cullin 3a	0.015	Human
dnaja2l	DnaJ (Hsp40) homolog, subfamily A, member 2, like	0.015
psmd4b	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b	0.014
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.014
skp1	S-phase kinase-associated protein 1	0.014
ubin	ataxin-1 ubiquitin-like interacting protein	0.014
brca2	breast cancer 2, early onset	0.014
f2r	coagulation factor II (thrombin) receptor	0.014
arhgap11a	Rho GTPase activating protein 11A	0.014
fas	Fas (TNF receptor superfamily, member 6)	0.014
smap1	stromal membrane-associated protein 1	0.014
atoh7	atonal homolog 7	0.014
rqcd1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.014
zgc:92321	zgc:92321	0.014
hs6st1b	heparan sulfate 6-O-sulfotransferase 1b	0.014
zgc:110687	zgc:110687	0.014
kif14	kinesin family member 14	0.014	Fly
ankrd13c	ankyrin repeat domain 13C	0.013
hoxc8a	homeo box C8a	0.013
lrmp	lymphoid-restricted membrane protein	0.013
mcm3	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)	0.013
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.013	Yeast
b4galt6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	0.013
gdi2	GDP dissociation inhibitor 2	0.013
krit1	KRIT1, ankyrin repeat containing	0.013
si:ch211-147d7.3	si:ch211-147d7.3	0.013
chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.013
usp14	ubiquitin specific protease 14 (tRNA-guanine transglycosylase)	0.013
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.013
myhz1.1	myosin, heavy polypeptide 1.1, skeletal muscle	0.013
ints8	integrator complex subunit 8	0.013
polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.013
tbc1d23	TBC1 domain family, member 23	0.013
zgc:113210	zgc:113210	0.013
pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.012	Human Worm
ppp2r1b	protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform	0.012
tmpoa	thymopoietin a	0.012
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.012
ahctf1	AT hook containing transcription factor 1	0.012
zgc:92607	zgc:92607	0.012
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.012
zgc:77262	zgc:77262	0.012
zgc:152900	zgc:152900	0.012
sfswap	splicing factor, suppressor of white-apricot homolog (Drosophila)	0.012
tbca	tubulin cofactor a	0.012
elof1	elongation factor 1 homolog (S. cerevisiae)	0.012
atad5a	ATPase family, AAA domain containing 5a	0.012
piwil1	piwi-like 1 (Drosophila)	0.012	Fly
ptena	phosphatase and tensin homolog A	0.012	Human Mouse
prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.012
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.012
si:ch211-255l12.1	si:ch211-255l12.1	0.011
sec23a	Sec23 homolog A (S. cerevisiae)	0.011
rae1	RAE1 RNA export 1 homolog (S. pombe)	0.011
ccne	cyclin E	0.011	Fly
grwd1	glutamate-rich WD repeat containing 1	0.011
h2afx	H2A histone family, member X	0.011
faf1	Fas associated factor 1	0.011
si:ch211-69g19.2	si:ch211-69g19.2	0.011
glmna	glomulin, FKBP associated protein a	0.011
im:7163548	im:7163548	0.011
psma5	proteasome (prosome, macropain) subunit, alpha type,5	0.011
epn1	epsin 1	0.011
gsna	gelsolin a	0.011
zgc:56699	zgc:56699	0.011
prpf4b	PRP4 pre-mRNA processing factor 4 homolog B	0.011
fam60al	family with sequence similarity 60, member A, like	0.011
ep300b	E1A binding protein p300 b	0.011
elmo1	engulfment and cell motility 1 (ced-12 homolog, C. elegans)	0.011
psmb3	proteasome (prosome, macropain) subunit, beta type, 3	0.011
cct8	chaperonin containing TCP1, subunit 8 (theta)	0.011
tbpl2	TATA box binding protein like 2	0.011
poc1a	POC1 centriolar protein homolog A (Chlamydomonas)	0.011
zgc:136346	zgc:136346	0.011
tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.011
zgc:153700	zgc:153700	0.010
aaas	achalasia, adrenocortical insufficiency, alacrimia	0.010
tuba4l	tubulin, alpha 4 like	0.010
zgc:123180	zgc:123180	0.010
csnk1g2a	casein kinase 1, gamma 2a	0.010
supt6h	suppressor of Ty 6 homolog	0.010
wu:fa96e12	wu:fa96e12	0.010
zgc:158643	zgc:158643	0.010
znf207b	zinc finger protein 207, b	0.010	Human
nop16	NOP16 nucleolar protein homolog (yeast)	0.010
rnps1	RNA binding protein S1, serine-rich domain	0.010
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.010