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Danio rerio

14 genes annotated in zebrafish

neural crest formation

The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neural crest formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neural crest formation" (in gray)

Name	Description	Probability
raraa	retinoic acid receptor, alpha a	0.770
foxd3	forkhead box D3	0.610
lfng	lunatic fringe homolog	0.444
dlx3b	distal-less homeobox gene 3b	0.401
foxi3a	forkhead box I3a	0.348
rarga	retinoic acid receptor gamma a	0.332
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.319
sox3	SRY-box containing gene 3	0.297
hoxb3a	homeo box B3a	0.271
sox2	SRY-box containing gene 2	0.267
hoxb2a	homeo box B2a	0.252
col10a1	collagen, type X, alpha 1	0.248
pcdh18a	protocadherin 18a	0.226
tp63	tumor protein p63	0.177
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.156
satb2	SATB homeobox 2	0.145
lect1	leukocyte cell derived chemotaxin 1	0.136
meis1	myeloid ecotropic viral integration 1	0.134
wnt8a	wingless-type MMTV integration site family, member 8a	0.131
otx2	orthodenticle homolog 2	0.129
znf703	zinc finger protein 703	0.122
zeb2a	zinc finger E-box binding homeobox 2a	0.119
msxb	muscle segment homeobox B	0.116
nrarpa	notch-regulated ankyrin repeat protein a	0.116
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.103
spry4	sprouty (Drosophila) homolog 4	0.095
col7a1l	collagen type VII alpha 1-like	0.093
sox19a	SRY-box containing gene 19a	0.086
si:ch211-57k11.10	si:ch211-57k11.10	0.072
eya1	eyes absent homolog 1	0.070
dlx2a	distal-less homeobox gene 2a	0.062
ptpra	protein tyrosine phosphatase, receptor type, A	0.061
actc1b	actin, alpha, cardiac muscle 1b	0.060
gata3	GATA-binding protein 3	0.056
zgc:85838	zgc:85838	0.055
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.053
gbx2	gastrulation brain homeo box 2	0.052
meis2.1	myeloid ecotropic viral integration site 2.1	0.052
zgc:111944	zgc:111944	0.052
foxi1	forkhead box I1	0.048
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.047
smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.045
alcama	activated leukocyte cell adhesion molecule a	0.043
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.042
dag1	dystroglycan 1	0.042
irx5a	iroquois homeobox protein 5a	0.042
LOC100334210	growth/differentiation factor 5-like	0.040
faf1	Fas associated factor 1	0.039
bmper	BMP binding endothelial regulator	0.039
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.038
znf503	zinc finger protein 503	0.038
dlx6a	distal-less homeobox gene 6a	0.038
jam3b	junctional adhesion molecule 3b	0.036
phf2	PHD finger protein 2	0.035
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.034
crestin	crestin	0.033
snai1a	snail homolog 1a (Drosophila)	0.033
hmgb1a	high-mobility group box 1a	0.033
foxo3a	forkhead box O3A	0.033
smc3	structural maintenance of chromosomes 3	0.032
roraa	RAR-related orphan receptor A, paralog a	0.032
rnd1l	Rho family GTPase 1 like	0.032
cdh2	cadherin 2, neuronal	0.032
zgc:136773	zgc:136773	0.031
id3	inhibitor of DNA binding 3	0.031
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.030
tfap2a	transcription factor AP-2 alpha	0.030
kdm4b	lysine (K)-specific demethylase 4B	0.029
pxn	paxillin	0.029
pcdh18b	protocadherin 18b	0.029
appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.028
zgc:101761	zgc:101761	0.028
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.028
lmo4a	LIM domain only 4a	0.028
cpsf6	cleavage and polyadenylation specific factor 6	0.028
ankrd12	ankyrin repeat domain 12	0.027
st8sia6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	0.027
fzd10	frizzled homolog 10	0.027
waca	WW domain containing adaptor with coiled-coil a	0.026
barx1	BarH-like homeobox 1	0.026
foxa3	forkhead box A3	0.026
jam2a	junctional adhesion molecule 2a	0.026
sec24d	SEC24 family, member D (S. cerevisiae)	0.025
nexn	nexilin (F actin binding protein)	0.025
igf1rb	insulin-like growth factor 1b receptor	0.025
foxb1.2	forkhead box B1.2	0.025
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.025
max	myc-associated factor X	0.025
pax6a	paired box gene 6a	0.024
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.024
ptk2.1	protein tyrosine kinase 2a	0.024
pbx4	pre-B-cell leukemia transcription factor 4	0.024
pcdh10b	protocadherin 10b	0.023
plxnb2b	plexin b2b	0.023
prdm1a	PR domain containing 1a, with ZNF domain	0.023
rarab	retinoic acid receptor, alpha b	0.022
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.022
ctnnb1	catenin (cadherin-associated protein), beta 1	0.022
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.022
zgc:66100	zgc:66100	0.022
acana	aggrecan a	0.021
csnk1g2a	casein kinase 1, gamma 2a	0.021
nrp2b	neuropilin 2b	0.021
six4b	sine oculis homeobox homolog 4b	0.021
gcm2	glial cells missing homolog 2 (Drosophila)	0.020
inka1a	induced in neural crest by AP2, 1a	0.020
sb:cb560	sb:cb560	0.020
chd7	chromodomain helicase DNA binding protein 7	0.020
tnpo3	transportin 3	0.020
si:ch211-173o4.2	si:ch211-173o4.2	0.020
scxa	scleraxis homolog A (mouse)	0.019
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.019
mapk3	mitogen-activated protein kinase 3	0.019
trim71	tripartite motif-containing 71	0.019
ntn2	netrin 2	0.019
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.019
zbtb4	zinc finger and BTB domain containing 4	0.019
dld	deltaD	0.018
rhoab	ras homolog gene family, member Ab	0.018
kop	askopos	0.018
auts2	autism susceptibility candidate 2	0.018
lrrtm1	leucine rich repeat transmembrane neuronal 1	0.018
syne2b	spectrin repeat containing, nuclear envelope 2b	0.018
acvr1b	activin A receptor, type IB	0.018
frem3	Fras1 related extracellular matrix 3	0.018
sumo2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.018
hoxa4a	homeo box A4a	0.018
ptprfb	protein tyrosine phosphatase, receptor type, f, b	0.018
rnd3a	Rho family GTPase 3a	0.017
pcdh19	protocadherin 19	0.017
gria1b	glutamate receptor, ionotropic, AMPA 1b	0.017
nkx2.3	NK2 transcription factor related 3	0.017
tcf12	transcription factor 12	0.017
ralgapa1	Ral GTPase activating protein, alpha subunit 1 (catalytic)	0.017
foxg1a	forkhead box G1a	0.017
metrn	meteorin, glial cell differentiation regulator	0.016
ap1g1	adaptor-related protein complex 1, gamma 1 subunit	0.016
cul1b	cullin 1b	0.016
sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.016
arid4a	AT rich interactive domain 4A (RBP1-like)	0.016
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.015
hspb1	heat shock protein, alpha-crystallin-related, 1	0.015
epha4b	eph receptor A4b	0.015
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.015
zgc:55573	zgc:55573	0.015
zgc:73311	zgc:73311	0.015
foxo3b	forkhead box O3b	0.015
ctsl1b	cathepsin L, 1 b	0.015
hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.015
osr1	odd-skipped related 1 (Drosophila)	0.015
naa15b	N(alpha)-acetyltransferase 15, NatA auxiliary subunit b	0.015
rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.015
nrp1b	neuropilin 1b	0.015
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.015
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.014
map2k7	mitogen-activated protein kinase kinase 7	0.014
fzd7b	frizzled homolog 7b	0.014
zgc:158603	zgc:158603	0.014
brap	BRCA1 associated protein	0.014
tfe3a	transcription factor binding to IGHM enhancer 3a	0.014
lzts2a	leucine zipper, putative tumor suppressor 2a	0.014
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.014
wu:fb80a07	wu:fb80a07	0.014
scn4ab	sodium channel, voltage-gated, type IV, alpha, b	0.014
cdx1b	caudal type homeobox 1 b	0.014
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.014
atg5	ATG5 autophagy related 5 homolog (S. cerevisiae)	0.014
mlphb	melanophilin b	0.014
pitx3	paired-like homeodomain transcription factor 3	0.014
foxi3b	forkhead box I3b	0.014
uxs1	UDP-glucuronic acid decarboxylase 1	0.014
ptena	phosphatase and tensin homolog A	0.014
gria3a	glutamate receptor, ionotropic, AMPA 3a	0.013
ssrp1b	structure specific recognition protein 1b	0.013
wnt5a	wingless-type MMTV integration site family, member 5a	0.013
smc1al	structural maintenance of chromosomes 1A, like	0.013
cdc42	cell division cycle 42	0.013
spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.013
rmnd5b	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.013
snx27	sorting nexin family member 27	0.013
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.013
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
mmp15a	matrix metallopeptidase 15a	0.013
klhl11	kelch-like 11 (Drosophila)	0.013
sb:cb81	sb:cb81	0.013
mapk6	mitogen-activated protein kinase 6	0.013
wu:fi04c06	wu:fi04c06	0.013
hspa12b	heat shock protein 12B	0.013
wu:fb58e05	wu:fb58e05	0.012
zeb2b	zinc finger E-box binding homeobox 2b	0.012
lmo3	LIM domain only 3	0.012
celf2	cugbp, Elav-like family member 2	0.012
ppp2r5ea	protein phosphatase 2, regulatory subunit B', epsilon isoform a	0.012
ash1l	ash1 (absent, small, or homeotic)-like (Drosophila)	0.012
notch2	notch homolog 2	0.012
tgfbi	transforming growth factor, beta-induced	0.012
zgc:101598	zgc:101598	0.012
six3a	sine oculis homeobox homolog 3a	0.012
irx1a	iroquois homeobox protein 1, a	0.012
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.012
dixdc1a	DIX domain containing 1a	0.012
supt6h	suppressor of Ty 6 homolog	0.012
spg11	spastic paraplegia 11	0.012
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.012
gata2a	GATA-binding protein 2a	0.012
kdm1a	lysine (K)-specific demethylase 1a	0.012
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.012
fgf5	fibroblast growth factor 5	0.012
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.012
wif1	wnt inhibitory factor 1	0.012
bmp3	bone morphogenetic protein 3	0.012
nfia	nuclear factor I/A	0.012
trim8	tripartite motif-containing 8	0.011
si:dkey-202c5.1	si:dkey-202c5.1	0.011
wu:fq41a10	wu:fq41a10	0.011
mga	MAX gene associated	0.011
rnf41	ring finger protein 41	0.011
tfec	transcription factor EC	0.011
hmx3	homeo box (H6 family) 3	0.011
gria1a	glutamate receptor, ionotropic, AMPA 1a	0.011
usp10	ubiquitin specific peptidase 10	0.011
myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.011
b4galt6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	0.011
efnb2b	ephrin B2b	0.011
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.011
naa15a	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a	0.011
meis3	myeloid ecotropic viral integration site 3	0.011
arfip1	ADP-ribosylation factor interacting protein 1 (arfaptin 1)	0.011
snx12	sorting nexin 12	0.011
rargb	retinoic acid receptor, gamma b	0.011
hand2	heart and neural crest derivatives expressed transcript 2	0.011
phf8	PHD finger protein 8	0.011
kbp	kif1-binding protein	0.011
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.011
zgc:85942	zgc:85942	0.011
id:ibd2050	id:ibd2050	0.011
robo3	roundabout homolog 3	0.011
tyrp1	tyrosinase-related protein 1	0.011
ncl	nucleolin	0.011
macf1	microtubule-actin crosslinking factor 1	0.011
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.011
syncripl	synaptotagmin binding, cytoplasmic RNA interacting protein, like	0.010
brpf1	bromodomain and PHD finger containing, 1	0.010
rfng	radical fringe homolog (Drosophila)	0.010
LOC100536439	parathyroid hormone-related protein-like	0.010
rdh10a	retinol dehydrogenase 10a	0.010
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.010
ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.010
fgf1	fibroblast growth factor 1	0.010
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.010
vim	vimentin	0.010
hs6st1b	heparan sulfate 6-O-sulfotransferase 1b	0.010
sox1a	SRY-box containing gene 1a	0.010
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.010
ctbp2	C-terminal binding protein 2	0.010
skib	nuclear oncoprotein skib	0.010
camsap1l1	calmodulin regulated spectrin-associated protein 1-like 1	0.010
spna2	spectrin alpha 2	0.010
gria3b	glutamate receptor, ionotrophic, AMPA 3b	0.010