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Danio rerio

13 genes annotated in zebrafish

signal transduction by p53 class mediator

An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "signal transduction by p53 class mediator"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "signal transduction by p53 class mediator" (in gray)

Name	Description	Probability	Func Analog Organism
spc24	SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.094
zgc:65861	zgc:65861	0.089
gins2	GINS complex subunit 2	0.082
tp53	tumor protein p53	0.078
nolc1	nucleolar and coiled-body phosphoprotein 1	0.069
krt4	keratin 4	0.067
nrp2b	neuropilin 2b	0.061
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.060
pola2	polymerase (DNA directed), alpha 2	0.056
surf6	surfeit 6	0.050
ccng1	cyclin G1	0.047
prmt1	protein arginine methyltransferase 1	0.044
dnmt5	DNA (cytosine-5-)-methyltransferase 5	0.044
LOC100536647	disintegrin and metalloproteinase domain-containing protein 10-like	0.043
ppp4ca	protein phosphatase 4 (formerly X), catalytic subunit a	0.043
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.042
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.042
irf6	interferon regulatory factor 6	0.040
wls	wntless homolog (Drosophila)	0.038
zgc:73328	zgc:73328	0.038
smc3	structural maintenance of chromosomes 3	0.038
thoc3	THO complex 3	0.037
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.036
chek1	CHK1 checkpoint homolog (S. pombe)	0.036
fsta	follistatin a	0.035
sema3aa	semaphorin 3aa	0.034
hug	HuG	0.033
rnf7	ring finger protein 7	0.033
bcl2l1	bcl2-like 1	0.033
rp2	retinitis pigmentosa 2 (X-linked recessive)	0.031
eaf2	ELL associated factor 2	0.030
brip1	BRCA1 interacting protein C-terminal helicase 1	0.030
dnajb12	DnaJ (Hsp40) homolog, subfamily B, member 12	0.030
zgc:101661	zgc:101661	0.029
ogt.2	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2	0.029
card9	caspase recruitment domain family, member 9	0.028
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.028
lin7c	lin-7 homolog C (C. elegans)	0.027
mif	macrophage migration inhibitory factor	0.026	Mouse
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.026
celf1	cugbp, Elav-like family member 1	0.025
znf703	zinc finger protein 703	0.025
rnf144ab	ring finger protein 144ab	0.025
cdc45	CDC45 cell division cycle 45 homolog (S. cerevisiae)	0.024
odc1	ornithine decarboxylase 1	0.024
sf3b1	splicing factor 3b, subunit 1	0.024
uspl1	ubiquitin specific peptidase like 1	0.024
vax2	ventral anterior homeobox 2	0.024
gsc	goosecoid	0.024
si:dkey-77a20.7	si:dkey-77a20.7	0.023
vsx2	visual system homeobox 2	0.023
ccnl1	cyclin L1	0.022
fanci	Fanconi anemia, complementation group I	0.022
hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.022
pld1a	phospholipase D1a	0.022
foxi2	forkhead box I2	0.021
rps6kal	ribosomal protein S6 kinase, like	0.021	Human
rbm39a	RNA binding motif protein 39a	0.021
prmt5	protein arginine methyltransferase 5	0.021
timm13	translocase of inner mitochondrial membrane 13 homolog (yeast)	0.021
zgc:111944	zgc:111944	0.021
zgc:92321	zgc:92321	0.021
kif14	kinesin family member 14	0.021
cdh1	cadherin 1, epithelial	0.020
ankrd13c	ankyrin repeat domain 13C	0.020
chic2	cysteine-rich hydrophobic domain 2	0.020
eif2s1l	eukaryotic translation initiation factor 2, subunit 1 alpha, like	0.020
sass6	spindle assembly 6 homolog (C. elegans)	0.019
lsm1	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.019
tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.019
xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.019
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.019
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.019
orc3	origin recognition complex, subunit 3	0.018
ube2q2	ubiquitin-conjugating enzyme E2Q family member 2	0.018
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.018
nucks1a	nuclear casein kinase and cyclin-dependent kinase substrate 1a	0.018
scrt1b	scratch homolog 1, zinc finger protein b (Drosophila)	0.018
bbc3	BCL2 binding component 3	0.018
srsf6b	serine/arginine-rich splicing factor 6b	0.018
igf2a	insulin-like growth factor 2a	0.018
pax8	paired box gene 8	0.017
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.017
rps12	ribosomal protein S12	0.017
zff9	zinc finger protein 9	0.017
esco2	establishment of cohesion 1 homolog 2	0.017
eya2	eyes absent homolog 2 (Drosophila)	0.017
tfe3b	transcription factor binding to IGHM enhancer 3b	0.017
maea	macrophage erythroblast attacher	0.016
hnrnpa0l	heterogeneous nuclear ribonucleoprotein A0, like	0.016
arhgap11a	Rho GTPase activating protein 11A	0.016
aida	axin interaction partner and dorsalization antagonist	0.016
zgc:114188	zgc:114188	0.016
notch2	notch homolog 2	0.016
ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.016
LOC555279	hypothetical LOC555279	0.016
eif1b	eukaryotic translation initiation factor 1B	0.016
acss2	acyl-CoA synthetase short-chain family member 2	0.016
p2rx3b	purinergic receptor P2X, ligand-gated ion channel, 3b	0.016
prdm8b	PR domain containing 8b	0.016
fam173b	family with sequence similarity 173, member B	0.016
zgc:103517	zgc:103517	0.016
rps21	ribosomal protein S21	0.016
prdm2b	PR domain containing 2, with ZNF domain b	0.015
rplp2	ribosomal protein, large P2	0.015
mbd3a	methyl-CpG binding domain protein 3a	0.015
dnajc5ga	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a	0.015
zgc:100817	zgc:100817	0.015
wdhd1	WD repeat and HMG-box DNA binding protein 1	0.015
sid4	secreted immunoglobulin domain 4	0.015
sf3b5	splicing factor 3b, subunit 5	0.015
zgc:114097	zgc:114097	0.015
ublcp1	ubiquitin-like domain containing CTD phosphatase 1	0.015
si:ch211-153j24.6	si:ch211-153j24.6	0.015
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.014
rplp1	ribosomal protein, large, P1	0.014
spry4	sprouty (Drosophila) homolog 4	0.014
mkln1	muskelin 1, intracellular mediator containing kelch motifs	0.014
ahcy	S-adenosylhomocysteine hydrolase	0.014
jak3	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	0.014
zgc:86598	zgc:86598	0.014
smn1	survival motor neuron 1	0.014
max	myc-associated factor X	0.014
ralgapa1	Ral GTPase activating protein, alpha subunit 1 (catalytic)	0.014
rarga	retinoic acid receptor gamma a	0.014
tfdp1a	transcription factor Dp-1, a	0.014
eny2	enhancer of yellow 2 homolog (Drosophila)	0.014
cry1b	cryptochrome 1b	0.014
rab11ba	RAB11B, member RAS oncogene family, a	0.014
otx1b	orthodenticle homolog 1b	0.014
sox9a	SRY-box containing gene 9a	0.014
glmna	glomulin, FKBP associated protein a	0.014
jag2	jagged 2	0.014
cnot6	CCR4-NOT transcription complex, subunit 6	0.014
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.013
rad54l	RAD54-like (S. cerevisiae)	0.013
c20orf20	c20orf20 homolog (H. sapiens)	0.013
tipin	timeless interacting protein	0.013
il7r	interleukin 7 receptor	0.013
ipo9	importin 9	0.013
mrps18b	mitochondrial ribosomal protein S18B	0.013
mapk14a	mitogen-activated protein kinase 14a	0.013
msh6	mutS homolog 6 (E. coli)	0.013
limk2	LIM domain kinase 2	0.013
efnb2a	ephrin B2a	0.013
zfand5b	zinc finger, AN1-type domain 5b	0.013
wdr18	WD repeat domain 18	0.013
bmp5	bone morphogenetic protein 5	0.013
nop58	NOP58 ribonucleoprotein homolog (yeast)	0.013
abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.013
uck2a	uridine-cytidine kinase 2a	0.013
tgif1	TGFB-induced factor homeobox 1	0.012
nme2b.1	non-metastatic cells 2b.1, protein (NM23B) expressed in	0.012
zgc:55307	zgc:55307	0.012
dhfr	dihydrofolate reductase	0.012
nop10	NOP10 ribonucleoprotein homolog (yeast)	0.012
LOC560369	TIM21-like protein, mitochondrial-like	0.012
zgc:101724	zgc:101724	0.012
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.012
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.012
cdk10	cyclin-dependent kinase 10	0.012
pum1	pumilio homolog 1 (Drosophila)	0.012
kdm5c	lysine (K)-specific demethylase 5C	0.012
ptk2.1	protein tyrosine kinase 2a	0.012
efna2	ephrin A2	0.012
npm1	nucleophosmin 1	0.012	Mouse
snrnp27	small nuclear ribonucleoprotein 27 (U4/U6.U5)	0.012
taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto	0.012
chuk	conserved helix-loop-helix ubiquitous kinase	0.012
papolb	poly(A) polymerase beta (testis specific)	0.012
mknk2b	MAP kinase-interacting serine/threonine kinase 2b	0.012
traip	TRAF-interacting protein	0.012
zgc:73107	zgc:73107	0.012
bactin1	bactin1	0.011
dlx3b	distal-less homeobox gene 3b	0.011
zgc:56272	zgc:56272	0.011
siah1	seven in absentia homolog 1 (Drosophila)	0.011
zgc:77056	zgc:77056	0.011
ppme1	protein phosphatase methylesterase 1	0.011
h3f3a	H3 histone, family 3A	0.011
puf60a	poly-U binding splicing factor a	0.011
suz12b	suppressor of zeste 12 homolog (Drosophila) b	0.011
saal1	serum amyloid A-like 1	0.011
bhlhe22	basic helix-loop-helix family, member e22	0.011
eif4g3	eukaryotic translation initiation factor 4 gamma, 3	0.011
alk	anaplastic lymphoma kinase (Ki-1)	0.011
ndel1b	nudE nuclear distribution gene E homolog like 1 (A. nidulans) B	0.011
vax1	ventral anterior homeobox 1	0.011
zgc:103670	zgc:103670	0.011
stat5.2	signal transducer and activator of transcription 5.2	0.011
eif4a1a	eukaryotic translation initiation factor 4A, isoform 1A	0.011
sp4	sp4 transcription factor	0.011
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
ryk	receptor-like tyrosine kinase	0.011
exosc9	exosome component 9	0.011
zgc:92648	zgc:92648	0.011
mrps34	mitochondrial ribosomal protein S34	0.011
ddr2b	discoidin domain receptor family, member 2b	0.011
spint1a	serine peptidase inhibitor, Kunitz type 1 a	0.011
csnk1db	casein kinase 1, delta b	0.011
msi2b	musashi homolog 2b (Drosophila)	0.011
LOC555739	serine/threonine-protein kinase LMTK1-like	0.011
cul1b	cullin 1b	0.011
gdf11	growth differentiation factor 11	0.011
eif4e	eukaryotic translation initiation factor 4e	0.011
uba2	ubiquitin-like modifier activating enzyme 2	0.011
zgc:73230	zgc:73230	0.011
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.011
mrpl17	mitochondrial ribosomal protein L17	0.011
LOC567405	novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK)	0.011
fgf24	fibroblast growth factor 24	0.011
foxk2	forkhead box K2	0.011
tprb	translocated promoter region b (to activated MET oncogene)	0.011
rplp2l	ribosomal protein, large P2, like	0.011
sfswap	splicing factor, suppressor of white-apricot homolog (Drosophila)	0.011
smyd3	SET and MYND domain containing 3	0.011
ppm1bb	protein phosphatase, Mg2+/Mn2+ dependent, 1Bb	0.011
dcun1d5	DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)	0.010
psen1	presenilin 1	0.010
foxa3	forkhead box A3	0.010
srsf5a	serine/arginine-rich splicing factor 5a	0.010
epc2	enhancer of polycomb homolog 2 (Drosophila)	0.010
rb1	retinoblastoma 1	0.010
negr1	neuronal growth regulator 1	0.010
rbm17	RNA binding motif protein 17	0.010
foxn4	forkhead box N4	0.010
zgc:64116	zgc:64116	0.010
cmt4b2	Charcot-Marie-Tooth neuropathy 4B2 homolog (human)	0.010
atg12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.010
zgc:194876	zgc:194876	0.010
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.010
atxn7l2a	ataxin 7-like 2a	0.010
spry2	sprouty homolog 2	0.010