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Danio rerio

14 genes annotated in zebrafish

protein modification by small protein conjugation or removal

A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein modification by small protein conjugation or removal"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein modification by small protein conjugation or removal" (in gray)

Name	Description	Probability	Func Analog Organism
cdh2	cadherin 2, neuronal	0.172
cops3	COP9 constitutive photomorphogenic homolog subunit 3	0.072
tp53	tumor protein p53	0.067
cry5	cryptochrome 5	0.064
fmr1	fragile X mental retardation 1	0.060
zgc:55347	zgc:55347	0.044
psmd4b	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b	0.043	Fly
mcmbp	minichromosome maintenance complex binding protein	0.041
ube2d2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.040	Yeast
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.039
lmo4a	LIM domain only 4a	0.039
nod1	nucleotide-binding oligomerization domain containing 1	0.038
bmi1	B lymphoma Mo-MLV insertion region 1	0.036	Human Mouse
sox11b	SRY-box containing gene 11b	0.036
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.033
tfr1a	transferrin receptor 1a	0.030
tshz1	teashirt family zinc finger 1	0.030
robo3	roundabout homolog 3	0.028
snai1a	snail homolog 1a (Drosophila)	0.028
zgc:55573	zgc:55573	0.027
ogt.2	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2	0.027
foxd3	forkhead box D3	0.027
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.026
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.025	Human
rqcd1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.025
notch1a	notch homolog 1a	0.024
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.024	Yeast
zgc:100927	zgc:100927	0.023
ccnb1	cyclin B1	0.022
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.022
zgc:55733	zgc:55733	0.022
phf6	PHD finger protein 6	0.022
sept6	septin 6	0.022
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.022	Human
cul1a	cullin 1a	0.021	Human Mouse
lzic	leucine zipper and CTNNBIP1 domain containing	0.021
cdh23	cadherin-like 23	0.021
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.021
h2afv	H2A histone family, member V	0.020
col2a1a	collagen type II, alpha-1a	0.020
LOC566708	FL cytokine receptor-like	0.020
nop14	NOP14 nucleolar protein homolog (yeast)	0.020
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.020
lama1	laminin, alpha 1	0.019
cnot6	CCR4-NOT transcription complex, subunit 6	0.019
cdt1	chromatin licensing and DNA replication factor 1	0.019
eif1b	eukaryotic translation initiation factor 1B	0.019
gmnn	geminin, DNA replication inhibitor	0.019
h3f3a	H3 histone, family 3A	0.019
srsf1b	serine/arginine-rich splicing factor 1b	0.018
eif4h	eukaryotic translation initiation factor 4h	0.018
zgc:174506	zgc:174506	0.018
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.018
pop7	processing of precursor 7, ribonuclease P family	0.018
psmd11b	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b	0.018
cand1	cullin-associated and neddylation-dissociated 1	0.018	Human Worm
arpp19a	cAMP-regulated phosphoprotein 19a	0.018
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.017
gro2	groucho 2	0.017
ube2a	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.017	Human Yeast Mouse Fly
zgc:86903	zgc:86903	0.017
ppp6r3	protein phosphatase 6, regulatory subunit 3	0.016
psmd11a	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11a	0.016
uxs1	UDP-glucuronic acid decarboxylase 1	0.016
smfn	small fragment nuclease	0.016
axin1	axin 1	0.016	Human Mouse
psmc6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.016
mt2	metallothionein 2	0.016
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.016
csnk1db	casein kinase 1, delta b	0.016
cdc20	cell division cycle 20 homolog	0.016	Human Yeast Fly
chuk	conserved helix-loop-helix ubiquitous kinase	0.016
tial1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.016
eed	embryonic ectoderm development	0.016
glmna	glomulin, FKBP associated protein a	0.016
foxo3b	forkhead box O3b	0.016
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.016
tbc1d23	TBC1 domain family, member 23	0.015
ggps1	geranylgeranyl diphosphate synthase 1	0.015
lef1	lymphocyte enhancer binding factor 1	0.015
klhdc10	kelch domain containing 10	0.015
pgrmc2	progesterone receptor membrane component 2	0.015
wrb	tryptophan rich basic protein	0.015
thap11	THAP domain containing 11	0.015
meis1	myeloid ecotropic viral integration 1	0.015
foxi1	forkhead box I1	0.015
ck2a2a	casein kinase 2 alpha 2a	0.015	Fly
gps1	G protein pathway suppressor 1	0.015	Human Fly
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.015
otx5	orthodenticle homolog 5	0.015
wu:fd23d07	wu:fd23d07	0.015
rrm1	ribonucleotide reductase M1 polypeptide	0.015
zgc:152954	zgc:152954	0.014
psmc5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.014
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.014
rybpa	RING1 and YY1 binding protein a	0.014
desma	desmin a	0.014
fkbp1aa	FK506 binding protein 1Aa	0.014
si:ch211-153j24.6	si:ch211-153j24.6	0.014
otud7b	OTU domain containing 7B	0.014
fbxl14a	F-box and leucine-rich repeat protein 14a	0.014
psmb5	proteasome (prosome, macropain) subunit, beta type, 5	0.014
rpa3	replication protein A3	0.014
rmnd5b	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.014
e2f5	E2F transcription factor 5	0.014
phf17	PHD finger protein 17	0.014
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.014
zgc:55448	zgc:55448	0.014
mkrn2	makorin, ring finger protein, 2	0.014
dnmt1	DNA (cytosine-5-)-methyltransferase 1	0.013
ext2	exostoses (multiple) 2	0.013
tbx2b	T-box 2b	0.013
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.013
uck2a	uridine-cytidine kinase 2a	0.013
dynlrb1	dynein, light chain, roadblock-type 1	0.013
cry2a	cryptochrome 2a	0.013
zgc:73100	zgc:73100	0.013
ppp3r1b	protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b	0.013
wnt10a	wingless-type MMTV integration site family, member 10a	0.013
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.013
irf6	interferon regulatory factor 6	0.013
gtf2a1	general transcription factor IIA, 1	0.013
ptch1	patched 1	0.013
stambpb	STAM binding protein b	0.013
prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.013
cnot10	CCR4-NOT transcription complex, subunit 10	0.013
senp3a	SUMO1/sentrin/SMT3 specific peptidase 3a	0.013
rbb4l	retinoblastoma binding protein 4, like	0.013
hirip5	HIRA interacting protein 5	0.013
whsc2	Wolf-Hirschhorn syndrome candidate 2	0.013
piga	phosphatidylinositol glycan anchor biosynthesis, class A	0.013
dirc2	disrupted in renal carcinoma 2	0.013
siah1	seven in absentia homolog 1 (Drosophila)	0.013	Human Mouse
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.013	Mouse
zgc:55943	zgc:55943	0.012
arpp19b	cAMP-regulated phosphoprotein 19b	0.012
zgc:92775	zgc:92775	0.012
cnpy1	canopy1	0.012
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.012
mib	mind bomb	0.012
smarcb1a	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a	0.012
cdca8	cell division cycle associated 8	0.012
ercc2	excision repair cross-complementing rodent repair deficiency, complementation group 2	0.012
dda1	DET1 and DDB1 associated 1	0.012
usp5	ubiquitin specific protease 5	0.012	Human Fly
ppil4	peptidylprolyl isomerase (cyclophilin)-like 4	0.012
ythdf3	YTH domain family 3	0.012
sall1a	sal-like 1a (Drosophila)	0.012
atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.012
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.012
ldb1a	LIM-domain binding factor 1a	0.012
zgc:111944	zgc:111944	0.012
drg2	developmentally regulated GTP binding protein 2	0.011
ofd1	oral-facial-digital syndrome 1	0.011
zgc:64114	zgc:64114	0.011
ube2v2	ubiquitin-conjugating enzyme E2 variant 2	0.011
tubgcp2	tubulin, gamma complex associated protein 2	0.011
strap	serine/threonine kinase receptor associated protein	0.011
mecp2	methyl CpG binding protein 2	0.011
pppde1	PPPDE peptidase domain containing 1	0.011
acvr1b	activin A receptor, type IB	0.011
pbrm1l	polybromo 1, like	0.011
runx1	runt-related transcription factor 1	0.011
six4.3	sine oculis homeobox homolog 4.3	0.011
stk11	serine/threonine kinase 11	0.011
efnb2a	ephrin B2a	0.011
gmcl1	germ cell-less homolog 1 (Drosophila)	0.011
bbc3	BCL2 binding component 3	0.011
wipi2	WD repeat domain, phosphoinositide interacting 2	0.011
tmed4	transmembrane emp24 protein transport domain containing 4	0.011
caprin1a	cell cycle associated protein 1a	0.011
epc2	enhancer of polycomb homolog 2 (Drosophila)	0.011
farsb	phenylalanyl-tRNA synthetase, beta subunit	0.011
med4	mediator complex subunit 4	0.011
wu:fi25h02	wu:fi25h02	0.011
ipo9	importin 9	0.011
limk2	LIM domain kinase 2	0.011
mitd1	MIT, microtubule interacting and transport, domain containing 1	0.011
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.011
manf	mesencephalic astrocyte-derived neurotrophic factor	0.011
fbxw11a	F-box and WD-40 domain protein 11a	0.011	Human Mouse Fly
psmd13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.011
prps1b	phosphoribosyl pyrophosphate synthetase 1B	0.011
ccdc94	coiled-coil domain containing 94	0.011
ash2l	ash2 (absent, small, or homeotic)-like (Drosophila)	0.011
pycrl	pyrroline-5-carboxylate reductase-like	0.010
hoxa2b	homeo box A2b	0.010
zgc:73265	zgc:73265	0.010
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.010
sox2	SRY-box containing gene 2	0.010
sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.010	Human Mouse
vps26a	vacuolar protein sorting 26 homolog A (yeast)	0.010
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.010
orc1	origin recognition complex, subunit 1	0.010
txnrd1	thioredoxin reductase 1	0.010
prpsap2	phosphoribosyl pyrophosphate synthetase-associated protein 2	0.010
cfl2l	cofilin 2, like	0.010
sf3b1	splicing factor 3b, subunit 1	0.010
slc39a6	solute carrier family 39 (zinc transporter), member 6	0.010
rsrc2	arginine/serine-rich coiled-coil 2	0.010
fras1	Fraser syndrome 1	0.010
robo1	roundabout homolog 1	0.010
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.010
hgfa	hepatocyte growth factor a	0.010
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.010