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Danio rerio

4 genes annotated in zebrafish

gene silencing

Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gene silencing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "gene silencing" (in gray)

Name	Description	Probability	Func Analog Organism
dnmt1	DNA (cytosine-5-)-methyltransferase 1	0.138	Mouse
paf1	paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.128
ssrp1a	structure specific recognition protein 1a	0.117
ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.108
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.079
snrpa	small nuclear ribonucleoprotein polypeptide A	0.072	Worm
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.064
cbx5	chromobox homolog 5 (HP1 alpha homolog, Drosophila)	0.059	Fly
rpa1	replication protein A1	0.054
drg1	developmentally regulated GTP binding protein 1	0.054
tcea1	transcription elongation factor A (SII), 1	0.053
fen1	flap structure-specific endonuclease 1	0.051
ahctf1	AT hook containing transcription factor 1	0.049
zgc:55876	zgc:55876	0.049
ndr1	nodal-related 1	0.049
rrm1	ribonucleotide reductase M1 polypeptide	0.049
zgc:77052	zgc:77052	0.048
wnt5b	wingless-type MMTV integration site family, member 5b	0.046
snrpc	small nuclear ribonucleoprotein polypeptide C	0.046
whsc1	Wolf-Hirschhorn syndrome candidate 1	0.044
setd8b	SET domain containing (lysine methyltransferase) 8b	0.042
marcksb	myristoylated alanine rich protein kinase C substrate b	0.041
rbm17	RNA binding motif protein 17	0.040
hmgb1a	high-mobility group box 1a	0.040
ncl	nucleolin	0.037
wdr5	WD repeat domain 5	0.036
rbb4	retinoblastoma binding protein 4	0.036	Yeast Worm Fly
ss18	synovial sarcoma translocation, chromosome 18 (H. sapiens)	0.035
nin	ninein (GSK3B interacting protein)	0.033
mettl11a	methyltransferase like 11A	0.033
suv39h1a	suppressor of variegation 3-9 homolog 1a	0.032	Human
sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.031
ryr1b	ryanodine receptor 1b (skeletal)	0.031
ezh2	enhancer of zeste homolog 2 (Drosophila)	0.031
pola2	polymerase (DNA directed), alpha 2	0.031
hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.030
srsf4	serine/arginine-rich splicing factor 4	0.029
gro1	groucho 1	0.029
pes	pescadillo	0.029
wdr82	WD repeat domain containing 82	0.028
sox11b	SRY-box containing gene 11b	0.028
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.027
suv39h1b	suppressor of variegation 3-9 homolog 1b	0.027	Human
actl6a	actin-like 6A	0.027
rbmx	RNA binding motif protein, X-linked	0.027
smarce1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.026
akap12b	A kinase (PRKA) anchor protein (gravin) 12b	0.026
orc5	origin recognition complex, subunit 5	0.025
setb	SET translocation (myeloid leukemia-associated) B	0.025
srsf2	serine/arginine-rich splicing factor 2	0.025
zgc:113183	zgc:113183	0.025
sulf1	sulfatase 1	0.025
ewsr1b	Ewing sarcoma breakpoint region 1b	0.024
cdk8	cyclin-dependent kinase 8	0.024
mapre1	microtubule-associated protein, RP/EB family, member 1	0.024
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.024	Yeast
lancl1	LanC antibiotic synthetase component C-like 1 (bacterial)	0.024
ncaph	non-SMC condensin I complex, subunit H	0.024
slbp	stem-loop binding protein	0.023	Worm
orc1	origin recognition complex, subunit 1	0.023
ef1a	elongation factor 1-alpha	0.023
gtf2a1	general transcription factor IIA, 1	0.023
dcaf7	ddb1 and cul4 associated factor 7	0.023
smyd5	SMYD family member 5	0.023
pcbp2	poly(rC) binding protein 2	0.023
scaf11	SR-related CTD-associated factor 11	0.023
ehmt2	euchromatic histone-lysine N-methyltransferase 2	0.023
polr2gl	polymerase (RNA) II (DNA directed) polypeptide G-like	0.023
supt6h	suppressor of Ty 6 homolog	0.022
bactin2	bactin2	0.022
rbbp6	retinoblastoma binding protein 6	0.022
btg3	B-cell translocation gene 3	0.022
cyc1	cytochrome c-1	0.022
morc2	MORC family CW-type zinc finger 2	0.021
zgc:55701	zgc:55701	0.021
fgf20a	fibroblast growth factor 20a	0.021
hnrpr	heterogeneous nuclear ribonucleoprotein R	0.021
hnrnpa0l	heterogeneous nuclear ribonucleoprotein A0, like	0.021
stk11	serine/threonine kinase 11	0.021
zgc:101724	zgc:101724	0.021
LOC570775	protein argonaute-1-like	0.020
pola1	polymerase (DNA directed), alpha 1	0.020
tra2b	transformer 2 beta homolog (Drosophila)	0.020
ints6	integrator complex subunit 6	0.020
zgc:174506	zgc:174506	0.020
usp1	ubiquitin specific protease 1	0.020
eif2c4	eukaryotic translation initiation factor 2C, 4	0.019
sf1	splicing factor 1	0.019
mcm4	MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)	0.019
arpp19b	cAMP-regulated phosphoprotein 19b	0.019
ruvbl2	RuvB-like 2 (E. coli)	0.019	Worm
slit1a	slit homolog 1a (Drosophila)	0.019
ankrd13c	ankyrin repeat domain 13C	0.019
zgc:55461	zgc:55461	0.018
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.018	Worm
lmnb1	lamin B1	0.018	Fly
rnf2	ring finger protein 2	0.018	Fly
wdr43	WD repeat domain 43	0.018
ptges	prostaglandin E synthase	0.018
cct5	chaperonin containing TCP1, subunit 5 (epsilon)	0.018
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.017
g3bp1	GTPase activating protein (SH3 domain) binding protein 1	0.017
rab5ab	RAB5A, member RAS oncogene family, b	0.017
ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	0.017
setd2	SET domain containing 2	0.017
sap30bp	SAP30 binding protein and SAP30 binding protein	0.017
pcm1	pericentriolar material 1	0.017
snrpd3l	small nuclear ribonucleoprotein D3 polypeptide, like	0.017
zgc:65979	zgc:65979	0.017
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.017
sephs1	selenophosphate synthetase 1	0.017
smyd2a	SET and MYND domain containing 2a	0.017
ube2g1b	ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)	0.017
ccnt2b	cyclin T2b	0.017
nap1l1	nucleosome assembly protein 1, like 1	0.017	Worm
tbx1	T-box 1	0.017
dpf2l	D4, zinc and double PHD fingers family 2, like	0.016
gtf2b	general transcription factor IIB	0.016
smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.016
suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.016
fhla	four and a half LIM domains a	0.016
setdb1b	SET domain, bifurcated 1b	0.016	Fly
hnrnpl2	heterogeneous nuclear ribonucleoprotein L2	0.016
nono	non-POU domain containing, octamer-binding	0.016
nhp2	NHP2 ribonucleoprotein homolog (yeast)	0.016
si:ch211-105d11.3	si:ch211-105d11.3	0.016
ptmab	prothymosin, alpha b	0.015
tmem48	transmembrane protein 48	0.015
hspd1	heat shock 60kD protein 1 (chaperonin)	0.015
zgc:110113	zgc:110113	0.015
cse1l	chromosome segregation 1-like (S. cerevisiae)	0.015	Worm
nanos3	nanos homolog 3	0.015
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.015
setdb1a	SET domain, bifurcated 1a	0.015	Fly
eif4a3	eukaryotic translation initiation factor 4A, isoform 3	0.015
nolc1	nucleolar and coiled-body phosphoprotein 1	0.015
rpa2	replication protein A2	0.015
zgc:113210	zgc:113210	0.015
ehmt1a	euchromatic histone-lysine N-methyltransferase 1a	0.015
rnps1	RNA binding protein S1, serine-rich domain	0.015
mrpl15	mitochondrial ribosomal protein L15	0.015
orc6	origin recognition complex, subunit 6	0.015
strap	serine/threonine kinase receptor associated protein	0.015
ccnb1	cyclin B1	0.014
snrnp27	small nuclear ribonucleoprotein 27 (U4/U6.U5)	0.014
rpn2	ribophorin II	0.014
prdm11	PR domain containing 11	0.014
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.014
smarca5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.014	Yeast Mouse Worm
puf60b	poly-U binding splicing factor b	0.014
slc9a3.2	solute carrier family 9 (sodium/hydrogen exchanger), member 3.2	0.014
wu:fa99c08	wu:fa99c08	0.014
si:ch211-1n9.7	si:ch211-1n9.7	0.014
rps2	ribosomal protein S2	0.014
anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.014
rbpms2	RNA binding protein with multiple splicing 2	0.014
sf3b5	splicing factor 3b, subunit 5	0.014
csnk1a1	casein kinase 1, alpha 1	0.013
fgfrl1a	fibroblast growth factor receptor-like 1a	0.013
si:ch211-215h6.2	si:ch211-215h6.2	0.013
wu:fb39a06	wu:fb39a06	0.013
hnrnpa0	heterogeneous nuclear ribonucleoprotein A0	0.013
si:ch211-198a12.6	si:ch211-198a12.6	0.013
eif4a1a	eukaryotic translation initiation factor 4A, isoform 1A	0.013
zbtb4	zinc finger and BTB domain containing 4	0.013
ash2l	ash2 (absent, small, or homeotic)-like (Drosophila)	0.013
spry4	sprouty (Drosophila) homolog 4	0.013
rbm8a	RNA binding motif protein 8A	0.013
zgc:55671	zgc:55671	0.013
pik3r3	phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)	0.013
acin1a	apoptotic chromatin condensation inducer 1a	0.013
mcmbp	minichromosome maintenance complex binding protein	0.013
zgc:193933	zgc:193933	0.013
hirip3	HIRA interacting protein 3	0.013
otx1b	orthodenticle homolog 1b	0.013
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.013
mcm3	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)	0.013
tsr2	TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)	0.013
pgam5	phosphoglycerate mutase family member 5	0.013
zgc:112089	zgc:112089	0.013
eftud2	elongation factor Tu GTP binding domain containing 2	0.013
psmb3	proteasome (prosome, macropain) subunit, beta type, 3	0.013
nfe2l2	nuclear factor (erythroid-derived 2)-like 2	0.013
gmnn	geminin, DNA replication inhibitor	0.012
ctbp1	C-terminal binding protein 1	0.012
hmgb2a	high-mobility group box 2a	0.012
ehmt1b	euchromatic histone-lysine N-methyltransferase 1b	0.012
mphosph8	M-phase phosphoprotein 8	0.012
abcf2	ATP-binding cassette, sub-family F (GCN20), member 2	0.012
cbx2	chromobox homolog 2 (Drosophila Pc class)	0.012	Fly
glulb	glutamate-ammonia ligase (glutamine synthase) b	0.012
eif1b	eukaryotic translation initiation factor 1B	0.012
casc3	cancer susceptibility candidate 3	0.012
bzw1a	basic leucine zipper and W2 domains 1a	0.012
ilf2	interleukin enhancer binding factor 2	0.012
akirin1	akirin 1	0.012
rif1	RAP1 interacting factor homolog (yeast)	0.012
ppp6c	protein phosphatase 6, catalytic subunit	0.012
sox8	SRY-box containing gene 8	0.012
api5	apoptosis inhibitor 5	0.012
ppm1d	protein phosphatase 1D magnesium-dependent, delta isoform	0.012
acvr1b	activin A receptor, type IB	0.012
cdc42l	cell division cycle 42, like	0.012
zgc:100817	zgc:100817	0.012
polb	polymerase (DNA directed), beta	0.012
ext1b	exostoses (multiple) 1b	0.012
cirh1a	cirrhosis, autosomal recessive 1A (cirhin)	0.012
oaz2a	ornithine decarboxylase antizyme 2a	0.012
cherp	calcium homeostasis endoplasmic reticulum protein	0.012
mapk3	mitogen-activated protein kinase 3	0.012
hells	helicase, lymphoid-specific	0.012	Mouse
msh2	mutS homolog 2 (E. coli)	0.012	Yeast
ran	ras-related nuclear protein	0.012
sf3a1	splicing factor 3a, subunit 1	0.012	Worm
zfr	zinc finger RNA binding protein	0.012
fam76b	family with sequence similarity 76, member B	0.012
ssb	Sjogren syndrome antigen B (autoantigen La)	0.012
hddc2	HD domain containing 2	0.011
sf3b1	splicing factor 3b, subunit 1	0.011
piwil1	piwi-like 1 (Drosophila)	0.011
prdm8b	PR domain containing 8b	0.011
flr	fleer	0.011
zgc:77304	zgc:77304	0.011
zgc:77155	zgc:77155	0.011
metap1	methionyl aminopeptidase 1	0.011
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.011
nrf1	nuclear respiratory factor 1	0.011
mll2	myeloid/lymphoid or mixed-lineage leukemia 2	0.011
si:ch211-255l12.1	si:ch211-255l12.1	0.011
nkd2	naked cuticle homolog 2 and naked 2a	0.011
bmi1	B lymphoma Mo-MLV insertion region 1	0.011	Fly
zff9	zinc finger protein 9	0.011
axin1	axin 1	0.011
wu:fb63c04	wu:fb63c04	0.011
abce1	ATP-binding cassette, sub-family E (OABP), member 1	0.011
meis3	myeloid ecotropic viral integration site 3	0.011
gpr161	G protein-coupled receptor 161	0.011
hat1	histone acetyltransferase 1	0.011
spred1	sprouty-related, EVH1 domain containing 1	0.011
pom121	POM121 membrane glycoprotein (rat)	0.011
zgc:91910	zgc:91910	0.011
diexf	digestive organ expansion factor homolog	0.011
zgc:152873	zgc:152873	0.011
mcm6	MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)	0.011
slit1b	slit homolog 1b (Drosophila)	0.011
acvr1l	activin A receptor, type I like	0.011
eif6	eukaryotic translation initiation factor 6	0.011
ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.011
wu:fa97a01	wu:fa97a01	0.011
atf1	activating transcription factor 1	0.011
hnrnpu	heterogeneous nuclear ribonucleoprotein U	0.011
anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.011
gro2	groucho 2	0.011
sap18	sin3-associated polypeptide	0.011
ppp1cbl	protein phosphatase 1, catalytic subunit, beta isoform, like	0.011
usp5	ubiquitin specific protease 5	0.011
stam	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.011
whsc1l1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.011
ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b	0.011	Yeast
pou2f1a	POU class 2 homeobox 1a	0.011
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.011
wdhd1	WD repeat and HMG-box DNA binding protein 1	0.011
clta	clathrin, light chain (Lca)	0.010
faf1	Fas associated factor 1	0.010
prkcz	protein kinase C, zeta	0.010
zgc:158399	zgc:158399	0.010
rnf175	ring finger protein 175	0.010
psmc4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.010
suz12a	suppressor of zeste 12 homolog (Drosophila) a	0.010
slu7	SLU7 splicing factor homolog (S. cerevisiae)	0.010
wu:fb71f10	wu:fb71f10	0.010
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.010
atoh7	atonal homolog 7	0.010
myca	myelocytomatosis oncogene a	0.010
got2b	glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)	0.010
igf3	insulin-like growth factor 3	0.010
zgc:101598	zgc:101598	0.010
tyrp1b	tyrosinase-related protein 1b	0.010
ogdh	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	0.010
ube2d2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.010
uck2b	uridine-cytidine kinase 2b	0.010
wdr18	WD repeat domain 18	0.010
zgc:92139	zgc:92139	0.010
prp19	PRP19/PSO4 homolog (S. cerevisiae)	0.010
lsm4	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.010
prkci	protein kinase C, iota	0.010
rbm22	RNA binding motif protein 22	0.010
cnot6	CCR4-NOT transcription complex, subunit 6	0.010
mta3	metastasis associated family, member 3	0.010
mll4a	myeloid/lymphoid or mixed-lineage leukemia 4a	0.010	Mouse