IMP

Process View

Danio rerio

1 genes annotated in zebrafish

telomere maintenance

Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and the length of telomeric DNA. These processes includes those that shorten and lengthen the telomeric DNA sequences.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "telomere maintenance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "telomere maintenance" (in gray)

Name	Description	Probability	Func Analog Organism
sephs1	selenophosphate synthetase 1	0.164
rpa1	replication protein A1	0.127	Human Yeast
pola2	polymerase (DNA directed), alpha 2	0.100
si:ch211-1n9.7	si:ch211-1n9.7	0.084
poc1a	POC1 centriolar protein homolog A (Chlamydomonas)	0.073
asf1bb	ASF1 anti-silencing function 1 homolog Bb	0.067
rad51c	rad51 homolog C (S. cerevisiae)	0.067
bub3	BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)	0.061
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.060
ef1a	elongation factor 1-alpha	0.058
aaas	achalasia, adrenocortical insufficiency, alacrimia	0.055
cdc45	CDC45 cell division cycle 45 homolog (S. cerevisiae)	0.055
plk3	polo-like kinase 3 (Drosophila)	0.052
zgc:101661	zgc:101661	0.052
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.050
mus81	MUS81 endonuclease homolog (yeast)	0.050
anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.047
LOC567638	hypothetical LOC567638	0.046
lmnb1	lamin B1	0.041
tra2b	transformer 2 beta homolog (Drosophila)	0.041
mlh1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	0.039
rnaseh2a	ribonuclease H2, subunit A	0.039
orc5	origin recognition complex, subunit 5	0.038
mych	myelocytomatosis oncogene homolog	0.038
terfa	telomeric repeat binding factor a	0.036	Mouse
mcm7	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	0.035
tcea1	transcription elongation factor A (SII), 1	0.035
si:ch211-173p18.9	si:ch211-173p18.9	0.034
zgc:113143	zgc:113143	0.033
slc25a5	solute carrier family 25 alpha, member 5	0.033
rbb4	retinoblastoma binding protein 4	0.032
cdc7	cell division cycle 7 homolog (S. cerevisiae)	0.032
bmpr1bb	bone morphogenetic protein receptor, type 1bb	0.032
ofd1	oral-facial-digital syndrome 1	0.031
socs3a	suppressor of cytokine signaling 3a	0.030
hhip	hedgehog interacting protein	0.030
gins1	GINS complex subunit 1 (Psf1 homolog)	0.030
nme7	non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)	0.029
zgc:154089	zgc:154089	0.029
cisd2	CDGSH iron sulfur domain 2	0.029
anapc5	anaphase promoting complex subunit 5	0.029
si:dkey-9k8.1	si:dkey-9k8.1	0.027
myca	myelocytomatosis oncogene a	0.026
eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	0.025
hmga1a	high mobility group AT-hook 1a	0.024
zgc:123274	zgc:123274	0.024
cuedc2	CUE domain containing 2	0.024
mybl2	myeloblastosis oncogene-like 2	0.023
LOC100537814	kinetochore-associated protein 1-like	0.023
h3f3c	H3 histone, family 3C	0.023
arpp19b	cAMP-regulated phosphoprotein 19b	0.022
si:ch211-147d7.3	si:ch211-147d7.3	0.022
cand1	cullin-associated and neddylation-dissociated 1	0.022
tgfb2	transforming growth factor, beta 2	0.022
gins2	GINS complex subunit 2	0.021
uck2b	uridine-cytidine kinase 2b	0.021
zgc:110337	zgc:110337	0.021
usp1	ubiquitin specific protease 1	0.021
eif5a	eukaryotic translation initiation factor 5A	0.021
zgc:92172	zgc:92172	0.021
dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.020
zgc:56197	zgc:56197	0.020
vps37a	vacuolar protein sorting 37A	0.020
rcc2	regulator of chromosome condensation 2	0.020
lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.020
tpp1	tripeptidyl peptidase I	0.020
racgap1	Rac GTPase-activating protein 1	0.019
znf410	zinc finger protein 410	0.019
zgc:55943	zgc:55943	0.019
flot2a	flotillin 2a	0.019
zgc:73230	zgc:73230	0.019
zgc:77880	zgc:77880	0.019
prpsap2	phosphoribosyl pyrophosphate synthetase-associated protein 2	0.018
chuk	conserved helix-loop-helix ubiquitous kinase	0.018
zgc:123190	zgc:123190	0.018
zgc:92851	zgc:92851	0.017
zgc:77456	zgc:77456	0.017
ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.017
srsf1b	serine/arginine-rich splicing factor 1b	0.017
itfg2	integrin alpha FG-GAP repeat containing 2	0.017
ulk1b	unc-51-like kinase 1b (C. elegans)	0.017
pcid2	PCI domain containing 2	0.017
mcl1b	myeloid cell leukemia sequence 1b	0.017
lrrc42	leucine rich repeat containing 42	0.016
im:7136021	im:7136021	0.016
cbx3a	chromobox homolog 3a (HP1 gamma homolog, Drosophila)	0.016	Fly
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.016
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.016
si:dkey-189i22.1	si:dkey-189i22.1	0.016
plekha3	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3	0.016
trappc5	trafficking protein particle complex 5	0.016
tcerg1a	transcription elongation regulator 1a (CA150)	0.016
ncapg2	non-SMC condensin II complex, subunit G2	0.016
ighz	immunoglobulin heavy constant zeta	0.016
ints8	integrator complex subunit 8	0.015
st13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.015
ift57	intraflagellar transport protein 57	0.015
emp2	epithelial membrane protein 2	0.015
palb2	partner and localizer of BRCA2	0.015
hmgn2	high-mobility group nucleosomal binding domain 2	0.015
zgc:100817	zgc:100817	0.015
zgc:153290	zgc:153290	0.015
zgc:136346	zgc:136346	0.014
rab11ba	RAB11B, member RAS oncogene family, a	0.014
hat1	histone acetyltransferase 1	0.014
junb	jun B proto-oncogene	0.014
ncapd3	non-SMC condensin II complex, subunit D3	0.014
zgc:77165	zgc:77165	0.014	Human
faub	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b	0.014
sec61al1	Sec61 alpha like 1	0.014
rtn2a	reticulon 2a	0.014
cebpg	CCAAT/enhancer binding protein (C/EBP), gamma	0.014
eif3eb	eukaryotic translation initiation factor 3, subunit E, b	0.014
zgc:77849	zgc:77849	0.014
lhx2b	LIM homeobox 2b	0.014
paxip1	PAX interacting (with transcription-activation domain) protein 1	0.014
hp1bp3	heterochromatin protein 1, binding protein 3	0.014
maea	macrophage erythroblast attacher	0.014
srsf1a	serine/arginine-rich splicing factor 1a	0.014
wsb1	WD repeat and SOCS box-containing 1	0.014
spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.014
zgc:63611	zgc:63611	0.014
mycl1b	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b	0.013
bahcc1	BAH domain and coiled-coil containing 1	0.013
kcnk5	potassium channel, subfamily K, member 5	0.013
usp28	ubiquitin specific peptidase 28	0.013
riok1	RIO kinase 1 (yeast)	0.013
actr6	ARP6 actin-related protein 6 homolog (yeast)	0.013
rpl4	ribosomal protein L4	0.013
eef1g	eukaryotic translation elongation factor 1 gamma	0.013
trappc4	trafficking protein particle complex 4	0.013
rab30	RAB30, member RAS oncogene family	0.013
zgc:158604	zgc:158604	0.013
gab1	GRB2-associated binding protein 1	0.013
parvb	parvin, beta	0.013
mesp2	mesoderm posterior 2 homolog (mouse)	0.013
im:7153078	im:7153078	0.013
dntt	deoxynucleotidyltransferase, terminal	0.013
im:7150829	im:7150829	0.013
zw10	ZW10 homolog, centromere/kinetochore protein (Drosophila)	0.013
kcmf1	potassium channel modulatory factor 1	0.013
junbl	jun B proto-oncogene, like	0.013
sumo3b	SMT3 suppressor of mif two 3 homolog 3b	0.013
rnf175	ring finger protein 175	0.013
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.013
pfn2l	profilin 2 like	0.013
im:7150937	im:7150937	0.013
ckap5	cytoskeleton associated protein 5	0.013
mms22l	MMS22-like, DNA repair protein	0.013
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.013
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.013
zfand2a	zinc finger, AN1-type domain 2A	0.013
pms1	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	0.013
slu7	SLU7 splicing factor homolog (S. cerevisiae)	0.013
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.013
gpatch1	G patch domain containing 1	0.012
mospd1	motile sperm domain containing 1	0.012
zgc:112329	zgc:112329	0.012
sf3b3	splicing factor 3b, subunit 3	0.012
hemk1	HemK methyltransferase family member 1	0.012
snrpa	small nuclear ribonucleoprotein polypeptide A	0.012
sfxn4	sideroflexin 4	0.012
zgc:110577	zgc:110577	0.012
gbp	glycogen synthase kinase binding protein	0.012
golga7	golgi autoantigen, golgin subfamily a, 7	0.012
aup1	ancient ubiquitous protein 1	0.012
zgc:100974	zgc:100974	0.012
LOC570775	protein argonaute-1-like	0.012
rfc5	replication factor C (activator 1) 5	0.012
gstcd	glutathione S-transferase, C-terminal domain containing	0.012
f2r	coagulation factor II (thrombin) receptor	0.012
wdr82	WD repeat domain containing 82	0.012
march6	membrane-associated ring finger (C3HC4) 6	0.012
plekha1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.012
chp2	calcineurin B homologous protein 2	0.012
tial1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.012
ube2e3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)	0.012
pcnt1	pericentrin 1	0.012
pqbp1l	polyglutamine binding protein 1-like	0.012
im:7137778	im:7137778	0.012
plxna3	plexin A3	0.012
stip1	stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)	0.012
naa40	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)	0.012
h2afvl	H2A histone family, member V, like	0.012
zgc:110224	zgc:110224	0.012
zgc:86609	zgc:86609	0.012
tcf3	transcription factor 3	0.012
zgc:55652	zgc:55652	0.012
rplp1	ribosomal protein, large, P1	0.012
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.012
dia1	diaphorase (NADH) (cytochrome b-5 reductase)	0.012
acp1	acid phosphatase 1, soluble	0.012
ssr2	signal sequence receptor, beta	0.012
zgc:153941	zgc:153941	0.012
uprt	uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)	0.012
xpo1a	exportin 1 (CRM1 homolog, yeast) a	0.012
il15l	interleukin 15, like	0.012
trmt2b	TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)	0.012
sec14l1	SEC14-like 1 (S. cerevisiae)	0.011
crfb7	cytokine receptor family member b7	0.011
si:ch211-158b22.2	si:ch211-158b22.2	0.011
hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	0.011
zgc:66306	zgc:66306	0.011
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.011
wu:fa96e12	wu:fa96e12	0.011
ubl7	ubiquitin-like 7	0.011
akap8l	A kinase (PRKA) anchor protein 8-like	0.011
gatad1	GATA zinc finger domain containing 1	0.011
bactin2	bactin2	0.011
zgc:92661	zgc:92661	0.011
wdr24	WD repeat domain 24	0.011
fosl2	fos-like antigen 2	0.011
zgc:55671	zgc:55671	0.011
usf1	upstream transcription factor 1	0.011
trappc1	trafficking protein particle complex 1	0.011
snrpa1	small nuclear ribonucleoprotein polypeptide A'	0.011
si:ch211-173p18.1	si:ch211-173p18.1	0.011
ltk	leukocyte tyrosine kinase	0.011
paqr8	progestin and adipoQ receptor family member VIII	0.011
mettl16	methyltransferase like 16	0.011
znf346	zinc finger protein 346	0.011
nucks1a	nuclear casein kinase and cyclin-dependent kinase substrate 1a	0.011
im:7145024	im:7145024	0.011
si:dkey-42o15.2	si:dkey-42o15.2	0.011
im:7140055	im:7140055	0.011
nit1	nitrilase 1	0.011
zgc:56706	zgc:56706	0.011
zgc:175162	zgc:175162	0.011
mdn1	midasin homolog (yeast)	0.011
atp2b1b	ATPase, Ca++ transporting, plasma membrane 1b	0.011
zgc:165500	zgc:165500	0.011
vrk1	vaccinia related kinase 1	0.011
zgc:110758	zgc:110758	0.011
slc25a43	solute carrier family 25, member 43	0.011
vps26a	vacuolar protein sorting 26 homolog A (yeast)	0.011
zgc:55886	zgc:55886	0.011
prodha	proline dehydrogenase (oxidase) 1a	0.011
wu:fd58b11	wu:fd58b11	0.011
slc26a5	solute carrier family 26, member 5	0.011
poc1b	POC1 centriolar protein homolog B (Chlamydomonas)	0.011
wu:fj39b01	wu:fj39b01	0.011
si:ch211-149p10.2	si:ch211-149p10.2	0.011
alkbh3	alkB, alkylation repair homolog 3 (E. coli)	0.011
cratb	carnitine O-acetyltransferase b	0.011
tnfsf10l4	tumor necrosis factor (ligand) superfamily, member 10 like 4	0.011
rest	RE1-silencing transcription factor	0.011
eif2s3	eukaryotic translation initiation factor 2, subunit 3 gamma	0.011
slc24a5	solute carrier family 24, member 5	0.011
snrpd2	small nuclear ribonucleoprotein D2 polypeptide	0.011
flncb	filamin C, gamma b (actin binding protein 280)	0.011
zgc:56556	zgc:56556	0.011
zgc:112384	zgc:112384	0.011
zgc:101006	zgc:101006	0.011
ube2h	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.011
mkrn2	makorin, ring finger protein, 2	0.011
slc9a8	solute carrier family 9 (sodium/hydrogen exchanger), member 8	0.011
zgc:113340	zgc:113340	0.011
ppt1	palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)	0.011
zgc:63910	zgc:63910	0.011
nup155	nucleoporin 155	0.010
polr3glb	polymerase (RNA) III (DNA directed) polypeptide G like b	0.010
LOC100002342	carboxypeptidase A6-like	0.010
zgc:153292	zgc:153292	0.010
tdrd1	tudor domain containing 1	0.010
supt7l	suppressor of Ty 7 (S. cerevisiae)-like	0.010
zgc:63992	zgc:63992	0.010
im:7142489	im:7142489	0.010
grb10a	growth factor receptor-bound protein 10a	0.010
snrpe	small nuclear ribonucleoprotein polypeptide E	0.010
zgc:153997	zgc:153997	0.010
brd2b	bromodomain containing 2b	0.010
ash2l	ash2 (absent, small, or homeotic)-like (Drosophila)	0.010
zgc:101744	zgc:101744	0.010
tnpo2	transportin 2 (importin 3, karyopherin beta 2b)	0.010
peli2	pellino homolog 2 (Drosophila)	0.010
cenph	centromere protein H	0.010
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.010
zgc:91910	zgc:91910	0.010
si:ch211-79h18.3	si:ch211-79h18.3	0.010
LOC558023	hypothetical protein LOC558023	0.010
rpp21	ribonuclease P 21 subunit	0.010
hmg20b	high-mobility group 20B	0.010
nprl2	nitrogen permease regulator-like 2 (S. cerevisiae)	0.010
myh10	myosin, heavy polypeptide 10, non-muscle and myosin, heavy chain 10, non-muscle	0.010
epc2	enhancer of polycomb homolog 2 (Drosophila)	0.010
oaz2a	ornithine decarboxylase antizyme 2a	0.010
zgc:112403	zgc:112403	0.010
setdb1a	SET domain, bifurcated 1a	0.010
si:ch211-253b1.6	si:ch211-253b1.6	0.010
zgc:162619	zgc:162619	0.010
ier5	immediate early response 5	0.010
pus1	pseudouridine synthase 1	0.010
mcl1a	myeloid cell leukemia sequence 1a	0.010
angptl1	angiopoietin-like 1	0.010
nfyc	nuclear transcription factor Y, gamma	0.010
myo5ab	myosin VAb	0.010
sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.010
zgc:101016	zgc:101016	0.010
fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.010
cx52.9	connexin 52.9	0.010
fkbp5	FK506 binding protein 5	0.010
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.010
tmed4	transmembrane emp24 protein transport domain containing 4	0.010
rftn2	raftlin family member 2	0.010
zgc:113026	zgc:113026	0.010
dynll1	dynein, light chain, LC8-type 1	0.010
hip1r	huntingtin interacting protein 1 related	0.010