The network for 'cellular ketone metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

Drosophila melanogaster
Name Description Probability Func Analog Organism
drk downstream of receptor kinase 0.802
krz kurtz 0.770
ci cubitus interruptus 0.722
Mer Merlin 0.708
usp ultraspiracle 0.705
dib disembodied 0.690
Hcf Host cell factor 0.683
Cyp12d1-p CG30489 gene product from transcript CG30489-RA 0.682
Cbl CG7037 gene product from transcript CG7037-RB 0.665
rl rolled 0.599
shn schnurri 0.571
ash2 absent, small, or homeotic discs 2 0.554
mbc myoblast city 0.527
wts warts 0.509
HLHmdelta E(spl) region transcript mdelta 0.507
Egfr Epidermal growth factor receptor 0.477
Dad Daughters against dpp 0.468
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.436
Pvr PDGF- and VEGF-receptor related 0.424
E(spl) Enhancer of split 0.422
csw corkscrew 0.413
emc extra macrochaetae 0.412
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.407
CG5362 CG5362 gene product from transcript CG5362-RA 0.404
par-6 CG5884 gene product from transcript CG5884-RA 0.403
Ugt35a UDP-glycosyltransferase 35a 0.399
Smox Smad on X 0.394
dm diminutive 0.390
shg shotgun 0.372
pnt pointed 0.355
rho rhomboid 0.347
ago archipelago 0.343
kuz kuzbanian 0.337
HLHmgamma E(spl) region transcript mgamma 0.333
Ced-12 CG5336 gene product from transcript CG5336-RA 0.330
Atg1 Autophagy-specific gene 1 0.325
cno canoe 0.317
sog short gastrulation 0.316
awd abnormal wing discs 0.313
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.304
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.303
Sos Son of sevenless 0.298
Cyp28d1 CG10833 gene product from transcript CG10833-RA 0.297
Src42A Src oncogene at 42A 0.292
Akt1 CG4006 gene product from transcript CG4006-RA 0.290
shot short stop 0.285
hppy happyhour 0.275
aux auxillin 0.275
oc ocelliless 0.274
HLHm7 E(spl) region transcript m7 0.272
Phm Peptidylglycine-alpha-hydroxylating monooxygenase 0.264
tkv thickveins 0.257
myoglianin CG1838 gene product from transcript CG1838-RD 0.256
Tom Twin of m4 0.255
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.248
CG12672 CG12672 gene product from transcript CG12672-RA 0.248
wal walrus 0.245
Sucb CG10622 gene product from transcript CG10622-RA 0.244
ush u-shaped 0.242
Rel Relish 0.242
ry rosy 0.240
Cyp4e2 Cytochrome P450-4e2 0.237
alpha-Est7 alpha-Esterase-7 0.235
Mad Mothers against dpp 0.231
Cyp12d1-d CG33503 gene product from transcript CG33503-RA 0.229
Idh Isocitrate dehydrogenase 0.225
Dcp-1 Death caspase-1 0.217
HLHmbeta E(spl) region transcript mbeta 0.211
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.206
pbl pebble 0.205
aop anterior open 0.204
Moe Moesin 0.196
yip2 yippee interacting protein 2 0.196
dik diskette 0.194
chico CG5686 gene product from transcript CG5686-RB 0.193
Hr4 CG16902 gene product from transcript CG16902-RC 0.189
Su(var)2-10 Suppressor of variegation 2-10 0.187
raps rapsynoid 0.186
ewg erect wing 0.184
spas spastin 0.183
l(2)gl lethal (2) giant larvae 0.181
rut rutabaga 0.178
fzy fizzy 0.176
gek genghis khan 0.176
disco disconnected 0.175
Jafrac1 thioredoxin peroxidase 1 0.172
CG11570 CG11570 gene product from transcript CG11570-RA 0.172
Osi6 Osiris 6 0.171
rols rolling pebbles 0.171
caz cabeza 0.168
fas faint sausage 0.167
y yellow 0.164
CG8709 CG8709 gene product from transcript CG8709-RK 0.163
pyr pyramus 0.163
ninaE neither inactivation nor afterpotential E 0.162
Pk61C Protein kinase 61C 0.160
argos CG4531 gene product from transcript CG4531-RA 0.159
Cyp6a9 Cytochrome P450-6a9 0.159
foxo forkhead box, sub-group O 0.155
rpr reaper 0.154
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
cyp-35C1 Protein CYP-35C1 0.158
mel-26 Protein MEL-26 0.154
sma-6 Protein SMA-6 0.110
F53F10.2 Protein F53F10.2 0.109
cyp-35A3 Protein CYP-35A3 0.103
mdt-8 Protein MDT-8 0.084
D2030.3 Protein D2030.3 0.079
cyp-35A2 Protein CYP-35A2 0.079
sek-1 Protein SEK-1 0.076
daf-2 Protein DAF-2 0.073
egl-18 Protein EGL-18 0.067
tps-1 Protein TPS-1 0.064
egl-27 Protein EGL-27 0.064
CELE_C29F7.2 Protein C29F7.2 0.063
del-5 Protein DEL-5 0.062
C34D10.2 Protein C34D10.2 0.062
abl-1 Protein ABL-1 0.062
elt-2 Protein ELT-2 0.061
daf-1 Protein DAF-1 0.061
zoo-1 Protein ZOO-1 0.058
iff-1 Protein IFF-1 0.057
nhr-34 Protein NHR-34 0.056
hum-6 Protein HUM-6 0.056
klo-1 Protein KLO-1 0.056
ZC443.4 Protein ZC443.4 0.053
gcs-1 Protein GCS-1 0.052
glo-4 Protein GLO-4 0.051
H24G06.1 Protein H24G06.1 0.051
ptr-2 Protein PTR-2 0.048
Y40B1B.8 Protein Y40B1B.8 0.048
uri-1 Protein URI-1 0.048
nrde-3 Protein NRDE-3 0.047
mtm-3 Protein MTM-3 0.047
prp-21 Protein PRP-21 0.047
egl-5 Protein EGL-5 0.047
emb-8 Protein EMB-8 0.047
lag-1 Protein LAG-1 0.046
ZK1128.1 Protein ZK1128.1 0.046
Y44A6C.1 Protein Y44A6C.1 0.045
hda-2 Protein HDA-2 0.044
magi-1 Protein MAGI-1 0.043
CELE_C17E4.2 Protein C17E4.2 0.043
F28B3.1 Protein F28B3.1 0.043
trim-9 Protein TRIM-9 0.042
pxf-1 Protein PXF-1 0.042
F13H6.3 Protein F13H6.3 0.042
pkg-1 Protein PKG-1 0.041
CELE_W05H7.1 Protein W05H7.1 0.041
efa-6 Protein EFA-6 0.041
K03E6.7 Protein K03E6.7 0.040
cyp-35A5 Protein CYP-35A5 0.040
sas-5 Protein SAS-5 0.039
lin-7 Protein LIN-7 0.039
pde-2 Protein PDE-2 0.039
ric-3 Protein RIC-3 0.039
daf-5 Protein DAF-5 0.039
T08G11.1 Protein T08G11.1 0.038
cyp-35A4 Protein CYP-35A4 0.038
CELE_F59B2.2 Protein F59B2.2 0.038
cpt-1 Protein CPT-1 0.038
aak-2 Protein AAK-2 0.038
tag-303 Protein TAG-303 0.038
nhr-49 Protein NHR-49 0.038
CELE_Y75B8A.4 Protein Y75B8A.4 0.038
sto-4 Protein STO-4 0.038
T28B4.1 Protein T28B4.1 0.038
pmp-3 Protein PMP-3 0.038
arrd-25 Protein ARRD-25 0.037
epn-1 Protein EPN-1 0.037
CELE_C46H3.2 Protein C46H3.2 0.037
dhs-20 Protein DHS-20 0.037
F21A3.2 Protein F21A3.2 0.037
dap-3 Protein DAP-3 0.037
par-1 Protein PAR-1 0.036
ergo-1 Protein ERGO-1 0.036
cec-1 Protein CEC-1 0.036
vab-3 Protein VAB-3 0.035
gob-1 Protein GOB-1 0.035
aha-1 Protein AHA-1 0.035
inx-3 Protein INX-3 0.035
sel-10 Protein SEL-10 0.035
unc-94 Protein UNC-94 0.035
mep-1 Protein MEP-1 0.035
CELE_C17E4.6 Protein C17E4.6 0.035
sem-5 Protein SEM-5 0.035
mat-3 Protein MAT-3 0.035
nhr-19 Protein NHR-19 0.035
zag-1 Protein ZAG-1 0.034
png-1 Protein PNG-1 0.034
F10B5.2 Protein F10B5.2 0.034
tbg-1 Protein TBG-1 0.034
ced-12 Protein CED-12 0.034
icd-1 Protein ICD-1 0.034
C35B1.5 Protein C35B1.5 0.034
itr-1 Protein ITR-1 0.034
pes-7 Protein PES-7 0.033
zfp-1 Protein ZFP-1 0.033
atad-3 Protein ATAD-3 0.033
lin-25 Protein LIN-25 0.033
hpl-1 Protein HPL-1 0.033
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Danio rerio
Name Description Probability Func Analog Organism
fzd7a frizzled homolog 7a 0.694
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.652
rag1 recombination activating gene 1 0.652
bmp2b bone morphogenetic protein 2b 0.637
robo3 roundabout homolog 3 0.563
tal1 T-cell acute lymphocytic leukemia 1 0.515
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.481
bmp2a bone morphogenetic protein 2a 0.475
tert telomerase reverse transcriptase 0.475
igf1ra insulin-like growth factor 1a receptor 0.464
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.464
nrp2b neuropilin 2b 0.460
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.420
ighz immunoglobulin heavy constant zeta 0.392
cnr1 cannabinoid receptor 1 0.383
gata1a GATA binding protein 1a 0.368
cdx4 caudal type homeo box transcription factor 4 0.357
smad1 MAD homolog 1 (Drosophila) 0.349
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.329
tp53 tumor protein p53 0.327
fzd7b frizzled homolog 7b 0.314
fn1b fibronectin 1b 0.309
prox1 prospero-related homeobox gene 1 0.307
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.307
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.294
rhoub ras homolog gene family, member Ub 0.290
il6r interleukin 6 receptor 0.289
grn2 granulin 2 0.286
sdc2 syndecan 2 0.277
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.276
nr2f1a nuclear receptor subfamily 2, group F, member 1a 0.271
adipoql adiponectin, C1Q and collagen domain containing, like 0.271
ighz2 immunoglobulin heavy constant zeta2 0.267
ighm immunoglobulin heavy constant mu and immunoglobulin heavy constant mu 0.266
hmx2 H6 family homeobox 2 0.247
neo1 neogenin 1 0.246
nod1 nucleotide-binding oligomerization domain containing 1 0.246
tcf12 transcription factor 12 0.245
hhip hedgehog interacting protein 0.245
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.240
jag2 jagged 2 0.239
ube2i2 ubiquitin-conjugating enzyme E2I2 0.227
met met proto-oncogene (hepatocyte growth factor receptor) 0.224
sept9a septin 9a 0.219
dlx5a distal-less homeobox gene 5a 0.219
inha inhibin, alpha 0.218
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.218
mc1r melanocortin 1 receptor 0.215
LOC556849 ectonucleoside triphosphate diphosphohydrolase 5-like 0.215
lhcgr luteinizing hormone/choriogonadotropin receptor 0.215
cmyb transcription factor cmyb 0.211
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.210
tcf7l1b transcription factor 7-like 1b (T-cell specific, HMG-box) 0.210
foxp2 forkhead box P2 0.208
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.206
cds2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.206
mpx myeloid-specific peroxidase 0.199
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.198
epor erythropoietin receptor 0.197
mapk3 mitogen-activated protein kinase 3 0.192
brd2a bromodomain-containing 2a 0.190
si:ch211-173o4.2 si:ch211-173o4.2 0.187
slc12a10.2 solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2 0.187
wnt7bb wingless-type MMTV integration site family, member 7Bb 0.183
notch1a notch homolog 1a 0.179
ptgs1 prostaglandin-endoperoxide synthase 1 0.175
rxraa retinoid X receptor, alpha a 0.174
gadd45bb growth arrest and DNA-damage-inducible, beta b 0.171
plagl2 pleiomorphic adenoma gene-like 2 0.171
efnb2a ephrin B2a 0.168
tead3a TEA domain family member 3 a 0.166
lepr leptin receptor 0.165
dlg2 discs, large (Drosophila) homolog 2 0.163
wif1 wnt inhibitory factor 1 0.163
zgc:65979 zgc:65979 0.163
rxrab retinoid x receptor, alpha b 0.162
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.160
hgfb hepatocyte growth factor b 0.158
kal1a Kallmann syndrome 1a sequence 0.158
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.157
pomt2 protein-O-mannosyltransferase 2 0.157
igfbp1b insulin-like growth factor binding protein 1b 0.157
fn1 fibronectin 1 0.156
alcama activated leukocyte cell adhesion molecule a 0.156
raraa retinoic acid receptor, alpha a 0.155
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.154
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.153
gli1 GLI-Kruppel family member 1 0.152
zgc:66326 zgc:66326 0.152
sox4a SRY-box containing gene 4a 0.152
nr2f2 nuclear receptor subfamily 2, group F, member 2 0.151
bnc2 basonuclin 2 0.151
fgfr4 fibroblast growth factor receptor 4 0.150
boc brother of CDO 0.149
appa amyloid beta (A4) precursor protein a 0.149
socs3a suppressor of cytokine signaling 3a 0.149
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.148
grn1 granulin 1 0.146
vsx2 visual system homeobox 2 0.144
tp53bp2 tumor protein p53 binding protein, 2 0.143
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Homo sapiens
Name Description Probability Func Analog Organism
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
EGFR epidermal growth factor receptor 1.000
TP53 tumor protein p53 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.000
SMAD3 SMAD family member 3 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 1.000
ESR1 estrogen receptor 1 0.999
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.999
BCAR1 breast cancer anti-estrogen resistance 1 0.999
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.998
HNF4A hepatocyte nuclear factor 4, alpha 0.998
WDR5 WD repeat domain 5 0.997
GHR growth hormone receptor 0.997
MET met proto-oncogene (hepatocyte growth factor receptor) 0.997
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.997
SH3KBP1 SH3-domain kinase binding protein 1 0.996
TRAF1 TNF receptor-associated factor 1 0.995
SMAD2 SMAD family member 2 0.994
BTK Bruton agammaglobulinemia tyrosine kinase 0.992
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.991
FHL2 four and a half LIM domains 2 0.987
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.986
NRP1 neuropilin 1 0.986
VEGFA vascular endothelial growth factor A 0.985
RARA retinoic acid receptor, alpha 0.983
SYK spleen tyrosine kinase 0.982
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.982
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.981
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.980
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.980
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.979
PRKCA protein kinase C, alpha 0.979
FGFR2 fibroblast growth factor receptor 2 0.979
EP300 E1A binding protein p300 0.977
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.975
SPRR2A small proline-rich protein 2A 0.975
SFN stratifin 0.972
NCOA1 nuclear receptor coactivator 1 0.970
MAPT microtubule-associated protein tau 0.965
CREBBP CREB binding protein 0.964
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.958
PTPRC protein tyrosine phosphatase, receptor type, C 0.958
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.957
CBX5 chromobox homolog 5 0.956
PTEN phosphatase and tensin homolog 0.954
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.952
PAX3 paired box 3 0.949
TAL1 T-cell acute lymphocytic leukemia 1 0.949
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.948
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.946
ALB albumin 0.946
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.945
TADA3 transcriptional adaptor 3 0.944
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.943
BIRC3 baculoviral IAP repeat containing 3 0.942
BCL2 B-cell CLL/lymphoma 2 0.939
INSR insulin receptor 0.936
FGF1 fibroblast growth factor 1 (acidic) 0.934
RICTOR RPTOR independent companion of MTOR, complex 2 0.933
VAV1 vav 1 guanine nucleotide exchange factor 0.929
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.928
CAV1 caveolin 1, caveolae protein, 22kDa 0.928
APP amyloid beta (A4) precursor protein 0.925
SNX9 sorting nexin 9 0.924
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.924
ACTB actin, beta 0.924
SIRT1 sirtuin 1 0.921
GSK3B glycogen synthase kinase 3 beta 0.921
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.918
RXRA retinoid X receptor, alpha 0.917
BCL2L1 BCL2-like 1 0.916
TGFB1 transforming growth factor, beta 1 0.916
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.914
AR androgen receptor 0.914
MPDZ multiple PDZ domain protein 0.914
CCR5 chemokine (C-C motif) receptor 5 0.907
PTK2 PTK2 protein tyrosine kinase 2 0.907
TRADD TNFRSF1A-associated via death domain 0.906
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.906
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.902
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.902
NCOA6 nuclear receptor coactivator 6 0.900
TRAF3 TNF receptor-associated factor 3 0.896
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.895
GRB2 growth factor receptor-bound protein 2 0.895
AXL AXL receptor tyrosine kinase 0.894
SOCS1 suppressor of cytokine signaling 1 0.892
EPHA2 EPH receptor A2 0.892
APOE apolipoprotein E 0.891
SORBS3 sorbin and SH3 domain containing 3 0.890
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.890
ENG endoglin 0.888
POU5F1 POU class 5 homeobox 1 0.884
LRP6 low density lipoprotein receptor-related protein 6 0.883
TRAF2 TNF receptor-associated factor 2 0.882
ICAM1 intercellular adhesion molecule 1 0.871
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Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 1.000
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.999
Grb2 growth factor receptor bound protein 2 0.999
Apoe apolipoprotein E 0.997
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.995
Fgfr1 fibroblast growth factor receptor 1 0.995
Pparg peroxisome proliferator activated receptor gamma 0.994
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.991
Lepr leptin receptor 0.990
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.990
Ctnnb1 catenin (cadherin associated protein), beta 1 0.989
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.989
Ntf3 neurotrophin 3 0.988
Kl klotho 0.987
Shh sonic hedgehog 0.986
Stat3 signal transducer and activator of transcription 3 0.986
Pnpla2 patatin-like phospholipase domain containing 2 0.985
Emx1 empty spiracles homolog 1 (Drosophila) 0.985
Il6st interleukin 6 signal transducer 0.980
Rarg retinoic acid receptor, gamma 0.979
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.978
Cbl Casitas B-lineage lymphoma 0.978
Drd2 dopamine receptor D2 0.975
Axin1 axin 1 0.973
Gli3 GLI-Kruppel family member GLI3 0.973
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.972
Stat6 signal transducer and activator of transcription 6 0.965
Prox1 prospero-related homeobox 1 0.963
Lyz2 lysozyme 2 0.961
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.961
Kit kit oncogene 0.956
Apc adenomatosis polyposis coli 0.951
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.950
Bdnf brain derived neurotrophic factor 0.950
Nos1 nitric oxide synthase 1, neuronal 0.948
Tbx3 T-box 3 0.945
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.944
Irs1 insulin receptor substrate 1 0.941
Ifng interferon gamma 0.939
Cav1 caveolin 1, caveolae protein 0.938
Prkce protein kinase C, epsilon 0.938
Psen1 presenilin 1 0.937
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.934
Trp53 transformation related protein 53 0.931
Cd28 CD28 antigen 0.930
Csf1 colony stimulating factor 1 (macrophage) 0.930
Irs2 insulin receptor substrate 2 0.929
Ar androgen receptor 0.927
Smad1 MAD homolog 1 (Drosophila) 0.927
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.926
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.924
Rb1 retinoblastoma 1 0.923
Pdx1 pancreatic and duodenal homeobox 1 0.922
Egfr epidermal growth factor receptor 0.920
Emx2 empty spiracles homolog 2 (Drosophila) 0.919
Nos3 nitric oxide synthase 3, endothelial cell 0.917
Lep leptin 0.916
Flt4 FMS-like tyrosine kinase 4 0.915
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.913
Il1r1 interleukin 1 receptor, type I 0.909
Stat5a signal transducer and activator of transcription 5A 0.908
Efnb2 ephrin B2 0.904
Insr insulin receptor 0.904
Prrx1 paired related homeobox 1 0.904
Ephb2 Eph receptor B2 0.901
Slamf1 signaling lymphocytic activation molecule family member 1 0.900
Epor erythropoietin receptor 0.895
Rag2 recombination activating gene 2 0.891
Inpp5d inositol polyphosphate-5-phosphatase D 0.889
Cd44 CD44 antigen 0.888
Tgfb2 transforming growth factor, beta 2 0.886
Mmp9 matrix metallopeptidase 9 0.883
Zeb1 zinc finger E-box binding homeobox 1 0.883
Prf1 perforin 1 (pore forming protein) 0.878
Nfib nuclear factor I/B 0.877
Sfrp2 secreted frizzled-related protein 2 0.867
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.866
Pax8 paired box gene 8 0.864
Ghr growth hormone receptor 0.862
Gli2 GLI-Kruppel family member GLI2 0.860
Fyn Fyn proto-oncogene 0.860
Lhx3 LIM homeobox protein 3 0.860
Dab1 disabled homolog 1 (Drosophila) 0.859
Ren1 renin 1 structural 0.859
Lhx1 LIM homeobox protein 1 0.858
Hif1a hypoxia inducible factor 1, alpha subunit 0.855
Mmp15 matrix metallopeptidase 15 0.854
Gsc goosecoid homeobox 0.852
Cyld cylindromatosis (turban tumor syndrome) 0.847
Il10 interleukin 10 0.844
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.843
Esr1 estrogen receptor 1 (alpha) 0.833
Bmp4 bone morphogenetic protein 4 0.826
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.824
Ifngr1 interferon gamma receptor 1 0.820
Tek endothelial-specific receptor tyrosine kinase 0.818
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.817
Rxra retinoid X receptor alpha 0.813
Sox11 SRY-box containing gene 11 0.813
Hes2 hairy and enhancer of split 2 (Drosophila) 0.811
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.606
Acadm acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain 0.538
Jak1 Janus kinase 1 0.454
Anxa5 annexin A5 0.449
Anxa2 annexin A2 0.435
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.407
Etfdh electron-transferring-flavoprotein dehydrogenase 0.390
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.340
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.337
Prdx1 peroxiredoxin 1 0.334
Aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.327
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.322
Adam17 ADAM metallopeptidase domain 17 0.319
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.312
Gja5 gap junction protein, alpha 5 0.304
Ppia peptidylprolyl isomerase A (cyclophilin A) 0.288
LOC293989 cytochrome P450-like 0.283
Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 0.277
Cd4 Cd4 molecule 0.270
Cps1 carbamoyl-phosphate synthetase 1 0.270
Nfib nuclear factor I/B 0.270
Agtr1a angiotensin II receptor, type 1a 0.268
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.258
Igfals insulin-like growth factor binding protein, acid labile subunit 0.258
Hck hemopoietic cell kinase 0.257
Etfa electron-transfer-flavoprotein, alpha polypeptide 0.255
Cd36 CD36 molecule (thrombospondin receptor) 0.248
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.246
RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase 0.243
Amh anti-Mullerian hormone 0.243
Mcee methylmalonyl CoA epimerase 0.242
Olr857 olfactory receptor 857 0.237
Mapk14 mitogen activated protein kinase 14 0.235
Clca4 chloride channel accessory 4 0.225
LOC494499 LOC494499 protein 0.223
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.220
Mef2d myocyte enhancer factor 2D 0.220
Gip gastric inhibitory polypeptide 0.217
Jak2 Janus kinase 2 0.215
Reg3g regenerating islet-derived 3 gamma 0.213
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.211
Dnase1l3 deoxyribonuclease 1-like 3 0.208
Gjb3 gap junction protein, beta 3 0.207
Vim vimentin 0.206
Smad3 SMAD family member 3 0.205
S100a6 S100 calcium binding protein A6 0.202
Mettl7b methyltransferase like 7B 0.199
Fgf5 fibroblast growth factor 5 0.194
Dbp D site of albumin promoter (albumin D-box) binding protein 0.194
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.193
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.190
Dio1 deiodinase, iodothyronine, type I 0.189
Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 0.188
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.187
Crip2 cysteine-rich protein 2 0.186
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.185
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.185
Gnrhr gonadotropin releasing hormone receptor 0.184
Mapk4 mitogen-activated protein kinase 4 0.182
Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase 0.182
Gata6 GATA binding protein 6 0.180
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.178
Myo1b myosin Ib 0.178
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.177
Ppp3r2 protein phosphatase 3, regulatory subunit B, beta isoform 0.177
Fgd4 FYVE, RhoGEF and PH domain containing 4 0.176
Acsl1 acyl-CoA synthetase long-chain family member 1 0.176
Akr1c18 aldo-keto reductase family 1, member C18 0.175
Sgk1 serum/glucocorticoid regulated kinase 1 0.172
Ptch1 patched homolog 1 (Drosophila) 0.170
Prkcd protein kinase C, delta 0.169
Ghr growth hormone receptor 0.163
Tshr thyroid stimulating hormone receptor 0.161
Tle4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 0.161
Afp alpha-fetoprotein 0.161
G6pc glucose-6-phosphatase, catalytic subunit 0.161
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.160
Grifin galectin-related inter-fiber protein 0.160
Cd200r1 CD200 receptor 1 0.160
Casp2 caspase 2 0.159
Pyy peptide YY (mapped) 0.158
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.157
Hrh2 histamine receptor H 2 0.156
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.155
Hlf hepatic leukemia factor 0.152
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.151
Dhfr dihydrofolate reductase 0.150
Bmp7 bone morphogenetic protein 7 0.149
Kcne1 potassium voltage-gated channel, Isk-related family, member 1 0.147
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.147
Ube2h ubiquitin-conjugating enzyme E2H 0.147
Plek pleckstrin 0.147
Ncr1 natural cytotoxicity triggering receptor 1 0.146
Kcnb2 potassium voltage gated channel, Shab-related subfamily, member 2 0.146
Agxt2 alanine-glyoxylate aminotransferase 2 0.145
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.144
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.144
Acat1 acetyl-coenzyme A acetyltransferase 1 0.144
Agxt alanine-glyoxylate aminotransferase 0.143
Ripk3 receptor-interacting serine-threonine kinase 3 0.143
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MET4 Met4p 0.586
GID8 Gid8p 0.446
CLA4 Cla4p 0.442
ARG81 Arg81p 0.397
YAP6 Yap6p 0.342
MET30 Met30p 0.317
PNC1 Pnc1p 0.308
CKA1 Cka1p 0.303
GID7 Gid7p 0.300
MIG2 Mig2p 0.300
BCK1 Bck1p 0.293
RAS2 Ras2p 0.266
GLN3 Gln3p 0.260
OAF1 Oaf1p 0.231
ARP8 Arp8p 0.216
RMD5 Rmd5p 0.208
KOG1 Kog1p 0.205
DOG2 Dog2p 0.202
VID24 Vid24p 0.200
ARE1 Are1p 0.187
MOH1 Moh1p 0.177
SPT16 Spt16p 0.176
COQ5 Coq5p 0.171
MGA2 Mga2p 0.165
SET1 Set1p 0.157
SNT1 Snt1p 0.156
MPM1 Mpm1p 0.153
DOA1 Doa1p 0.153
KEM1 Kem1p 0.152
RTG3 Rtg3p 0.141
SIN3 Sin3p 0.138
RTF1 Rtf1p 0.137
VID28 Vid28p 0.136
APD1 Apd1p 0.134
GRX2 Grx2p 0.133
CRD1 Crd1p 0.129
DBF2 Dbf2p 0.127
CTR9 Ctr9p 0.126
HSV2 Hsv2p 0.126
LYS5 Lys5p 0.119
RPN4 Rpn4p 0.119
GRE3 Gre3p 0.119
ARG80 Arg80p 0.118
HST1 Hst1p 0.117
FYV10 Fyv10p 0.116
HHT1 Hht1p 0.115
TRA1 Tra1p 0.114
COQ1 Coq1p 0.113
TPS1 Tps1p 0.112
CMK2 Cmk2p 0.112
CDC4 Cdc4p 0.112
HXK1 Hxk1p 0.111
CAT5 Cat5p 0.111
CKB2 Ckb2p 0.111
YTA7 Yta7p 0.109
FUS3 Fus3p 0.108
GPM2 Gpm2p 0.108
AVO1 Avo1p 0.106
NGG1 Ngg1p 0.105
MCM1 Mcm1p 0.105
MIG3 Mig3p 0.103
COQ10 Coq10p 0.103
HER1 Her1p 0.102
SWI6 Swi6p 0.100
ZWF1 Zwf1p 0.100
YER064C hypothetical protein 0.098
FMS1 Fms1p 0.097
RIM13 Rim13p 0.097
ROD1 Rod1p 0.097
GRE2 Gre2p 0.096
ALY1 Aly1p 0.096
YLR177W hypothetical protein 0.096
NOP10 Nop10p 0.094
STT4 Stt4p 0.092
RDS2 Rds2p 0.091
YAK1 Yak1p 0.090
LAT1 Lat1p 0.090
MPD1 Mpd1p 0.089
YRB2 Yrb2p 0.088
UBR1 Ubr1p 0.087
ZDS2 Zds2p 0.087
PXA2 Pxa2p 0.086
MLS1 Mls1p 0.085
COA4 Coa4p 0.084
LEO1 Leo1p 0.084
PGM2 Pgm2p 0.083
HSE1 Hse1p 0.083
YBR056W hypothetical protein 0.082
RTT109 Rtt109p 0.082
GIS1 Gis1p 0.081
CIS1 Cis1p 0.081
STP4 Stp4p 0.080
CHS2 Chs2p 0.080
RAD53 Rad53p 0.079
TOS3 Tos3p 0.079
SNF1 Snf1p 0.079
HTD2 Htd2p 0.078
SWD1 Swd1p 0.078
EMI5 Emi5p 0.076
GIC1 Gic1p 0.076