The network for 'peroxisome degradation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

peroxisome degradation

The process in which peroxisomes are delivered to the vacuole and degraded in response to changing nutrient conditions.

Drosophila melanogaster
Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PRKCZ protein kinase C, zeta 0.967
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.940
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.906
NCF1 neutrophil cytosolic factor 1 0.615
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.561
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.501
MAPK1 mitogen-activated protein kinase 1 0.462
NOXA1 NADPH oxidase activator 1 0.364
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.249
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.161
MAPK3 mitogen-activated protein kinase 3 0.147
ATG14 ATG14 autophagy related 14 homolog (S. cerevisiae) 0.133
F11R F11 receptor 0.130
ZNF71 zinc finger protein 71 0.108
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.101
NUMB numb homolog (Drosophila) 0.097
CCDC115 coiled-coil domain containing 115 0.094
PEBP4 phosphatidylethanolamine-binding protein 4 0.092
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.086
CDCP1 CUB domain containing protein 1 0.076
COG7 component of oligomeric golgi complex 7 0.073
SH3RF1 SH3 domain containing ring finger 1 0.071
BECN1 beclin 1, autophagy related 0.068
PRKCB protein kinase C, beta 0.062
UVRAG UV radiation resistance associated gene 0.055
MAPT microtubule-associated protein tau 0.053
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.052
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.051
PICK1 protein interacting with PRKCA 1 0.051
MAPK14 mitogen-activated protein kinase 14 0.049
DAPK1 death-associated protein kinase 1 0.035
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.034
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.034
VHL von Hippel-Lindau tumor suppressor 0.032
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.032
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.032
DUSP3 dual specificity phosphatase 3 0.031
ASXL1 additional sex combs like 1 (Drosophila) 0.029
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.027
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.027
COG1 component of oligomeric golgi complex 1 0.026
BAG3 BCL2-associated athanogene 3 0.026
DCTN1 dynactin 1 0.025
SQSTM1 sequestosome 1 0.024
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.023
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.022
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.021
BAG1 BCL2-associated athanogene 0.018
BAD BCL2-associated agonist of cell death 0.018
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.018
PDPK1 3-phosphoinositide dependent protein kinase-1 0.017
FYN FYN oncogene related to SRC, FGR, YES 0.017
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.017
CCL14 chemokine (C-C motif) ligand 14 0.017
PTPRR protein tyrosine phosphatase, receptor type, R 0.017
DLG1 discs, large homolog 1 (Drosophila) 0.016
CCHCR1 coiled-coil alpha-helical rod protein 1 0.016
SH2D1A SH2 domain containing 1A 0.015
BCL2 B-cell CLL/lymphoma 2 0.015
PRKCI protein kinase C, iota 0.015
SPRED1 sprouty-related, EVH1 domain containing 1 0.015
LCK lymphocyte-specific protein tyrosine kinase 0.015
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.015
TSC22D1 TSC22 domain family, member 1 0.014
NCKAP1 NCK-associated protein 1 0.014
LRRK2 leucine-rich repeat kinase 2 0.013
KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.013
PEBP1 phosphatidylethanolamine binding protein 1 0.012
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.012
UBXN6 UBX domain protein 6 0.012
NMT2 N-myristoyltransferase 2 0.012
RHEB Ras homolog enriched in brain 0.012
ELK1 ELK1, member of ETS oncogene family 0.011
PTK2B PTK2B protein tyrosine kinase 2 beta 0.011
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.011
CAPNS1 calpain, small subunit 1 0.011
SESN2 sestrin 2 0.010
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.010
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ATG9 Atg9p 0.736
SLT2 Slt2p 0.716
VPS38 Vps38p 0.705
KSS1 Kss1p 0.550
VPS15 Vps15p 0.500
ATG11 Atg11p 0.475
FUS3 Fus3p 0.468
PKC1 Pkc1p 0.371
ATG13 Atg13p 0.307
STE11 Ste11p 0.250
MSG5 Msg5p 0.240
COG3 Cog3p 0.239
RGD1 Rgd1p 0.175
KDX1 Kdx1p 0.160
COG1 Cog1p 0.153
STE5 Ste5p 0.150
COG6 Cog6p 0.134
ATG29 Atg29p 0.105
COG8 Cog8p 0.072
PEX6 Pex6p 0.072
BEM3 Bem3p 0.071
WSC3 Wsc3p 0.067
ATG14 Atg14p 0.067
ATG23 Atg23p 0.064
ATG26 Atg26p 0.060
RGD2 Rgd2p 0.060
STE2 Ste2p 0.046
BET3 Bet3p 0.046
VPS30 Vps30p 0.046
MSS4 Mss4p 0.045
SED5 Sed5p 0.042
MID2 Mid2p 0.041
COT1 Cot1p 0.038
SRD1 Srd1p 0.036
INP1 Inp1p 0.034
YOL038C-A hypothetical protein 0.033
VPS34 Vps34p 0.033
FLC2 Flc2p 0.033
DIG1 Dig1p 0.032
TEC1 Tec1p 0.031
LEU2 Leu2p 0.031
YAR068W hypothetical protein 0.031
SLG1 Slg1p 0.030
BRO1 Bro1p 0.030
ARP10 Arp10p 0.030
YLR162W hypothetical protein 0.028
HXT3 Hxt3p 0.028
BUL1 Bul1p 0.028
ISR1 Isr1p 0.027
YLR264C-A hypothetical protein 0.027
ARG8 Arg8p 0.026
CUP1-1 Cup1-1p 0.026
ICS2 Ics2p 0.026
PDR12 Pdr12p 0.026
ATG18 Atg18p 0.025
MER1 Mer1p 0.025
ATG21 Atg21p 0.025
SSN2 Ssn2p 0.025
REE1 Ree1p 0.025
NUT2 Nut2p 0.024
OCH1 Och1p 0.024
YPR157W hypothetical protein 0.024
APM1 Apm1p 0.024
SPL2 Spl2p 0.024
MF(ALPHA)2 Mf(alpha)2p 0.024
CTR2 Ctr2p 0.023
YLR042C hypothetical protein 0.023
ATP6 Atp6p 0.023
YAR066W hypothetical protein 0.023
GYL1 Gyl1p 0.022
PRS2 Prs2p 0.022
YIR035C hypothetical protein 0.022
GLG2 Glg2p 0.022
ATG1 Atg1p 0.022
YLR422W hypothetical protein 0.022
OPT2 Opt2p 0.022
ZPS1 Zps1p 0.022
THP3 Thp3p 0.022
YBR013C hypothetical protein 0.021
FMT1 Fmt1p 0.021
NPR2 Npr2p 0.021
AQY2 Aqy2p 0.021
HPF1 Hpf1p 0.021
YLR040C hypothetical protein 0.020
MF(ALPHA)1 Mf(alpha)1p 0.020
CDC55 Cdc55p 0.020
AIF1 Aif1p 0.020
SRX1 Srx1p 0.020
MON2 Mon2p 0.020
SSK1 Ssk1p 0.020
YLR108C hypothetical protein 0.020
YIL151C hypothetical protein 0.020
CNE1 Cne1p 0.020
PCL9 Pcl9p 0.019
YOL013W-A hypothetical protein 0.019
ERT1 Ert1p 0.019
YKR075C hypothetical protein 0.019
CRP1 Crp1p 0.019
AUA1 Aua1p 0.019
RHO1 Rho1p 0.019