The network for 'macromolecular complex assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macromolecular complex assembly

The aggregation, arrangement and bonding together of a set of macromolecules to form a complex.

Drosophila melanogaster
Name Description Probability Func Analog Organism
Moe Moesin 0.991
bsk basket 0.989
cpb capping protein beta 0.976
hyd hyperplastic discs 0.975
Mer Merlin 0.971
Khc Kinesin heavy chain 0.927
asp abnormal spindle 0.899
tsr twinstar 0.885
CaMKII Calcium/calmodulin-dependent protein kinase II 0.869
spas spastin 0.867
egl egalitarian 0.836
Sos Son of sevenless 0.835
Cp190 Centrosomal protein 190kD 0.833
Klp10A CG1453 gene product from transcript CG1453-RA 0.831
JIL-1 CG6297 gene product from transcript CG6297-RA 0.827
SNF1A SNF1A/AMP-activated protein kinase 0.827
eIF-4E Eukaryotic initiation factor 4E 0.817
Cip4 CG15015 gene product from transcript CG15015-RA 0.809
par-6 CG5884 gene product from transcript CG5884-RA 0.806
ncd non-claret disjunctional 0.805
CycB Cyclin B 0.792
BicD Bicaudal D 0.782
ena enabled 0.777
dlg1 discs large 1 0.776
Incenp Inner centromere protein 0.775
arm armadillo 0.774
Ras85D Ras oncogene at 85D 0.749
Arp66B Actin-related protein 66B 0.730
shot short stop 0.722
gig gigas 0.721
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.718
Mad Mothers against dpp 0.711
Mical Molecule interacting with CasL 0.674
Fs(2)Ket Female sterile (2) Ketel 0.668
Hsp27 Heat shock protein 27 0.657
par-1 CG8201 gene product from transcript CG8201-RA 0.649
CG4680 CG4680 gene product from transcript CG4680-RA 0.642
CycA Cyclin A 0.642
MRG15 CG6363 gene product from transcript CG6363-RA 0.639
CycE Cyclin E 0.637
msps mini spindles 0.636
Snr1 Snf5-related 1 0.635
Pink1 PTEN-induced putative kinase 1 0.633
Cdc42 CG12530 gene product from transcript CG12530-RA 0.623
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.619
G-oalpha47A G protein oalpha 47A 0.614
ben bendless 0.609
CtBP C-terminal Binding Protein 0.608
Pros26.4 Proteasome 26S subunit subunit 4 ATPase 0.599
CG10267 CG10267 gene product from transcript CG10267-RB 0.598
mod modulo 0.594
Nup154 Nucleoporin 154 0.592
BRWD3 CG31132 gene product from transcript CG31132-RA 0.592
stg string 0.591
Vps35 Vacuolar protein sorting 35 0.579
mars CG17064 gene product from transcript CG17064-RB 0.563
tacc transforming acidic coiled-coil protein 0.554
larp La related protein 0.554
wac wee Augmin 0.551
dnc dunce 0.539
wupA wings up A 0.534
Mcm5 Minichromosome maintenance 5 0.508
Abl Abl tyrosine kinase 0.503
Cctgamma CG8977 gene product from transcript CG8977-RC 0.501
Fas2 Fasciclin 2 0.496
pav pavarotti 0.492
hts hu li tai shao 0.479
HLHm7 E(spl) region transcript m7 0.477
gus gustavus 0.477
S6k RPS6-p70-protein kinase 0.476
E(spl) Enhancer of split 0.475
Taf1 TBP-associated factor 1 0.473
park parkin 0.462
sls sallimus 0.459
lwr lesswright 0.455
Rpt1 CG1341 gene product from transcript CG1341-RA 0.454
lds lodestar 0.450
Su(var)205 Suppressor of variegation 205 0.449
Marf Mitochondrial assembly regulatory factor 0.446
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.440
Mov34 CG3416 gene product from transcript CG3416-RA 0.435
HmgD High mobility group protein D 0.434
kay kayak 0.433
sle slender lobes 0.433
rl rolled 0.428
ovo CG6824 gene product from transcript CG6824-RE 0.424
dome domeless 0.423
dsh dishevelled 0.423
BubR1 Bub1-related kinase 0.422
His2Av Histone H2A variant 0.421
Pp2A-29B Protein phosphatase 2A at 29B 0.414
ftz-f1 ftz transcription factor 1 0.413
zip zipper 0.410
Klp3A Kinesin-like protein at 3A 0.406
betaTub56D beta-Tubulin at 56D 0.400
spd-2 spindle defective 2 0.399
CG5174 CG5174 gene product from transcript CG5174-RM 0.398
sty sprouty 0.390
Ephrin CG1862 gene product from transcript CG1862-RA 0.382
tws twins 0.381
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
atn-1 Protein ATN-1 0.419
rpt-5 Protein RPT-5 0.351
lmn-1 Protein LMN-1 0.292
pqn-59 Protein PQN-59 0.289
hcp-3 Protein HCP-3 0.263
acs-4 Protein ACS-4 0.244
lin-36 Protein LIN-36 0.244
deb-1 Protein DEB-1 0.241
mat-3 Protein MAT-3 0.228
ret-1 Protein RET-1 0.214
pkg-1 Protein PKG-1 0.210
mrt-2 Protein MRT-2 0.209
cks-1 Protein CKS-1 0.196
snr-5 Protein SNR-5 0.195
F11D5.1 Protein F11D5.1 0.191
plp-1 Protein PLP-1 0.191
C53B4.4 Protein C53B4.4 0.190
ubc-12 Protein UBC-12 0.190
tag-232 Protein TAG-232 0.188
lin-24 Protein LIN-24 0.188
let-858 Protein LET-858 0.181
act-4 Protein ACT-4 0.180
aap-1 Protein AAP-1 0.178
dpf-3 Protein DPF-3 0.177
ulp-1 Protein ULP-1 0.175
tag-260 Protein TAG-260 0.174
rpn-12 Protein RPN-12 0.173
CELE_C39E9.12 Protein C39E9.12 0.173
hlh-2 Protein HLH-2 0.170
unc-40 Protein UNC-40 0.168
D1081.8 Protein D1081.8 0.168
ZC395.10 Protein ZC395.10 0.167
his-1 Protein HIS-1 0.163
eat-6 Protein EAT-6 0.162
mig-2 Protein MIG-2 0.162
unc-54 Protein UNC-54 0.160
nud-1 Protein NUD-1 0.159
R90.1 Protein R90.1 0.159
lin-53 Protein LIN-53 0.155
C56G2.7 Protein C56G2.7 0.155
pha-4 Protein PHA-4 0.154
tag-163 Protein TAG-163 0.153
CELE_C24H12.4 Protein C24H12.4 0.151
T02H6.1 Protein T02H6.1 0.149
mcm-2 Protein MCM-2 0.149
F39G3.5 Protein F39G3.5 0.149
dpy-30 Protein DPY-30 0.148
mpk-1 Protein MPK-1 0.148
unc-112 Protein UNC-112 0.147
spd-5 Protein SPD-5 0.147
lst-1 Protein LST-1 0.147
mag-1 Protein MAG-1 0.146
kle-2 Protein KLE-2 0.146
rpb-2 Protein RPB-2 0.145
otub-1 Protein OTUB-1 0.145
dlc-1 Protein DLC-1 0.142
mcm-6 Protein MCM-6 0.141
CELE_Y75B8A.25 Protein Y75B8A.25 0.141
hsp-1 Protein HSP-1 0.141
cct-1 Protein CCT-1 0.141
pas-4 Protein PAS-4 0.139
npp-9 Protein NPP-9 0.139
nmy-2 Protein NMY-2 0.139
nol-5 Protein NOL-5 0.139
prx-5 Protein PRX-5 0.138
prp-8 Protein PRP-8 0.138
gsy-1 Protein GSY-1 0.137
smc-3 Protein SMC-3 0.136
dsh-2 Protein DSH-2 0.136
uba-1 Protein UBA-1 0.136
npl-4.2 Protein NPL-4.2 0.135
CELE_B0334.4 Protein B0334.4 0.135
K01G5.5 Protein K01G5.5 0.133
nhr-2 Protein NHR-2 0.133
zyg-9 Protein ZYG-9 0.132
T24H10.1 Protein T24H10.1 0.132
deps-1 Protein DEPS-1 0.131
rpn-8 Protein RPN-8 0.131
spc-1 Protein SPC-1 0.130
twk-18 Protein TWK-18 0.128
unc-53 Protein UNC-53 0.128
F56D2.6 Protein F56D2.6 0.124
spd-2 Protein SPD-2 0.123
klp-16 Protein KLP-16 0.123
his-64 Protein HIS-64 0.123
fbxa-108 Protein FBXA-108 0.122
egl-44 Protein EGL-44 0.122
T24F1.2 Protein T24F1.2 0.121
W02B12.10 Protein W02B12.10 0.121
vab-8 Protein VAB-8 0.121
let-418 Protein LET-418 0.120
pas-1 Protein PAS-1 0.120
xpo-2 Protein XPO-2 0.120
tars-1 Protein TARS-1 0.120
sun-1 Protein SUN-1 0.119
klp-7 Protein KLP-7 0.119
zyg-1 Protein ZYG-1 0.118
vab-3 Protein VAB-3 0.118
cap-2 Protein CAP-2 0.117
unc-9 Protein UNC-9 0.117
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Danio rerio
Name Description Probability Func Analog Organism
myog myogenin 0.535
lama4 laminin, alpha 4 0.370
mef2d myocyte enhancer factor 2d 0.348
tjp1 tight junction protein 1 (zona occludens 1) 0.305
gpia glucose phosphate isomerase a 0.301
setb SET translocation (myeloid leukemia-associated) B 0.289
pabpc1a poly A binding protein, cytoplasmic 1 a 0.247
chd chordin 0.235
rpa1 replication protein A1 0.227
arpc5a actin related protein 2/3 complex, subunit 5A 0.211
ccm2 cerebral cavernous malformation 2 0.210
srf serum response factor 0.209
nup107 nucleoporin 107 0.204
psma8 proteasome (prosome, macropain) subunit, alpha type, 8 0.197
ran ras-related nuclear protein 0.192
nsfa N-ethylmaleimide-sensitive factor a 0.189
tnni2a.4 troponin I, skeletal, fast 2a.4 0.189
bmp4 bone morphogenetic protein 4 0.188
alas2 aminolevulinate, delta-, synthetase 2 0.187
spaw southpaw 0.182
zgc:100838 zgc:100838 0.175
nop58 NOP58 ribonucleoprotein homolog (yeast) 0.173
msh6 mutS homolog 6 (E. coli) 0.173
cdh2 cadherin 2, neuronal 0.168
robo2 roundabout homolog 2 0.162
prpf8 pre-mRNA processing factor 8 0.161
cct7 chaperonin containing TCP1, subunit 7 (eta) 0.159
sass6 spindle assembly 6 homolog (C. elegans) 0.152
aldocb aldolase C, fructose-bisphosphate, b 0.150
cotl1 coactosin-like 1 (Dictyostelium) 0.146
snrnp70 small nuclear ribonucleoprotein 70 (U1) 0.138
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.137
nusap1 nucleolar and spindle associated protein 1 0.132
tnnt3b troponin T3b, skeletal, fast 0.126
myf6 myogenic factor 6 0.125
sptb spectrin, beta, erythrocytic 0.124
plxnb2a plexin b2a 0.124
atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide 0.124
psma1 proteasome (prosome, macropain) subunit, alpha type, 1 0.122
dusp6 dual specificity phosphatase 6 0.121
slc39a7 solute carrier family 39 (zinc transporter), member 7 0.119
caspa caspase a 0.116
rplp0 ribosomal protein, large, P0 0.114
tnnt2a troponin T2a, cardiac 0.112
cx43 connexin 43 0.112
tp53 tumor protein p53 0.111
pkd2 polycystic kidney disease 2 0.109
wu:fl55e11 wu:fl55e11 0.108
hsp90a.2 heat shock protein 90-alpha 2 0.108
vegfc vascular endothelial growth factor c 0.105
capza1b capping protein (actin filament) muscle Z-line, alpha 1b 0.100
ttna titin a 0.099
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.096
hnf4a hepatocyte nuclear factor 4, alpha 0.095
ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.095
mga MAX gene associated 0.095
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.094
hnrpl heterogeneous nuclear ribonucleoprotein L 0.093
cdc42 cell division cycle 42 0.093
eif4a1b eukaryotic translation initiation factor 4A, isoform 1B 0.092
plk1 polo-like kinase 1 (Drosophila) 0.092
atp1a3b ATPase, Na+/K+ transporting, alpha 3b polypeptide 0.091
psmb3 proteasome (prosome, macropain) subunit, beta type, 3 0.089
fabp3 fatty acid binding protein 3, muscle and heart 0.088
vcp valosin containing protein 0.088
ncor1 nuclear receptor co-repressor 1 0.085
anxa2a annexin A2a 0.084
nup88 nucleoporin 88 0.083
esco2 establishment of cohesion 1 homolog 2 0.082
zgc:65894 zgc:65894 0.082
sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) 0.082
nxph1 neurexophilin 1 0.081
mllt11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.081
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.080
ahctf1 AT hook containing transcription factor 1 0.080
hsp90a.1 heat shock protein 90-alpha 1 0.078
myhz1.2 myosin, heavy polypeptide 1.2, skeletal muscle 0.078
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.078
eomesa eomesodermin homolog a 0.078
igfbp1b insulin-like growth factor binding protein 1b 0.076
eif5a2 eukaryotic translation initiation factor 5A2 0.075
ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.075
ptch2 patched 2 0.074
gro1 groucho 1 0.074
cct3 chaperonin containing TCP1, subunit 3 (gamma) 0.074
eno3 enolase 3, (beta, muscle) 0.074
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.074
brd4 bromodomain containing 4 0.073
nasp nuclear autoantigenic sperm protein (histone-binding) 0.073
rbl1 retinoblastoma-like 1 (p107) 0.072
fbxw4 F-box and WD-40 domain protein 4 0.072
sulf2 sulfatase 2 0.071
nup93 nucleoporin 93 0.070
eml2 echinoderm microtubule associated protein like 2 0.069
anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.069
nap1l1 nucleosome assembly protein 1, like 1 0.069
sod1 superoxide dismutase 1, soluble 0.068
dtl denticleless homolog (Drosophila) 0.068
pbx4 pre-B-cell leukemia transcription factor 4 0.067
chd7 chromodomain helicase DNA binding protein 7 0.067
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.741
Mmp7 matrix metallopeptidase 7 0.712
Olfm1 olfactomedin 1 0.659
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.632
Sirpa signal-regulatory protein alpha 0.621
Avpr1b arginine vasopressin receptor 1B 0.609
Alas2 aminolevulinate, delta-, synthase 2 0.562
Hsp90b1 heat shock protein 90, beta, member 1 0.561
Vamp1 vesicle-associated membrane protein 1 0.555
Rhoa ras homolog gene family, member A 0.547
Hbb hemoglobin, beta 0.530
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.528
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.518
Ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.513
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.511
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.510
Exoc5 exocyst complex component 5 0.486
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.471
Cast calpastatin 0.469
St13 suppression of tumorigenicity 13 0.468
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.463
Tmed2 transmembrane emp24 domain trafficking protein 2 0.429
Anxa2 annexin A2 0.418
Nefl neurofilament, light polypeptide 0.407
Lepr leptin receptor 0.405
Col1a1 collagen, type I, alpha 1 0.404
Pygm phosphorylase, glycogen, muscle 0.404
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.401
Trim23 tripartite motif-containing 23 0.390
Col3a1 collagen, type III, alpha 1 0.388
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.386
RT1-Db1 RT1 class II, locus Db1 0.384
Arpc2 actin related protein 2/3 complex, subunit 2 0.377
RT1-Bb RT1 class II, locus Bb 0.376
Myh3 myosin, heavy chain 3, skeletal muscle, embryonic 0.372
Met met proto-oncogene 0.359
Efhd2 EF-hand domain family, member D2 0.357
Dlg4 discs, large homolog 4 (Drosophila) 0.356
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.354
Vav1 vav 1 guanine nucleotide exchange factor 0.352
Sycn syncollin 0.351
Jak1 Janus kinase 1 0.351
Jak2 Janus kinase 2 0.350
Map1a microtubule-associated protein 1A 0.348
Gad2 glutamate decarboxylase 2 0.344
Snap25 synaptosomal-associated protein 25 0.344
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.342
Casp2 caspase 2 0.339
Rab7a RAB7A, member RAS oncogene family 0.339
Cd80 Cd80 molecule 0.339
Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 0.338
Pak3 p21 protein (Cdc42/Rac)-activated kinase 3 0.338
Vim vimentin 0.338
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.336
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.334
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.332
Igfals insulin-like growth factor binding protein, acid labile subunit 0.332
Camk2b calcium/calmodulin-dependent protein kinase II beta 0.322
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.322
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.318
Rpl4 ribosomal protein L4 0.318
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.317
Mylk2 myosin light chain kinase 2 0.316
Scamp2 secretory carrier membrane protein 2 0.316
LOC100134871 beta globin minor gene 0.313
Anxa5 annexin A5 0.313
Chrne cholinergic receptor, nicotinic, epsilon 0.311
Taok1 TAO kinase 1 0.310
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.310
Plrg1 pleiotropic regulator 1, PRL1 homolog (Arabidopsis) 0.309
Cdc42 cell division cycle 42 (GTP binding protein) 0.308
Gip gastric inhibitory polypeptide 0.307
Stip1 stress-induced phosphoprotein 1 0.307
Reg3g regenerating islet-derived 3 gamma 0.307
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.307
S1pr2 sphingosine-1-phosphate receptor 2 0.306
Mapk1 mitogen activated protein kinase 1 0.304
LOC287167 globin, alpha 0.303
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.300
Gnao1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.298
Hba-a2 hemoglobin alpha, adult chain 2 0.297
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.294
Lbp lipopolysaccharide binding protein 0.294
Rab20 RAB20, member RAS oncogene family 0.293
Apba3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.293
Smad7 SMAD family member 7 0.292
Pttg1 pituitary tumor-transforming 1 0.292
Cfl1 cofilin 1, non-muscle 0.286
Hspd1 heat shock protein 1 (chaperonin) 0.282
Tagln2 transgelin 2 0.280
Wbp11 WW domain binding protein 11 0.278
RT1-Ba RT1 class II, locus Ba 0.273
Cxcl10 chemokine (C-X-C motif) ligand 10 0.272
Pdk4 pyruvate dehydrogenase kinase, isozyme 4 0.272
Scn5a sodium channel, voltage-gated, type V, alpha subunit 0.272
Psmb4 proteasome (prosome, macropain) subunit, beta type 4 0.271
Trhr2 thyrotropin releasing hormone receptor 2 0.269
Lig3 ligase III, DNA, ATP-dependent 0.269
Casp3 caspase 3 0.268
Lyz2 lysozyme 2 0.268
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism