The network for 'cytoskeleton organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
atn-1 Protein ATN-1 0.932
goa-1 Protein GOA-1 0.923
sem-5 Protein SEM-5 0.866
aspm-1 Protein ASPM-1 0.812
npp-7 Protein NPP-7 0.779
rpl-18 Protein RPL-18 0.738
unc-40 Protein UNC-40 0.711
unc-15 Protein UNC-15 0.679
prp-8 Protein PRP-8 0.670
nmy-2 Protein NMY-2 0.667
unc-43 Protein UNC-43 0.633
rpl-19 Protein RPL-19 0.632
tag-232 Protein TAG-232 0.620
gpr-1 Protein GPR-1 0.599
rpa-2 Protein RPA-2 0.579
pat-3 Protein PAT-3 0.567
npp-19 Protein NPP-19 0.538
act-4 Protein ACT-4 0.535
zyg-9 Protein ZYG-9 0.524
egl-8 Protein EGL-8 0.518
myo-3 Protein MYO-3 0.517
myo-1 Protein MYO-1 0.515
hcp-3 Protein HCP-3 0.510
pkg-1 Protein PKG-1 0.508
his-64 Protein HIS-64 0.501
rpl-15 Protein RPL-15 0.495
mpk-1 Protein MPK-1 0.489
acy-1 Protein ACY-1 0.482
CELE_C25A1.4 Protein C25A1.4 0.478
cysl-1 Protein CYSL-1 0.476
kgb-1 Protein KGB-1 0.475
lag-1 Protein LAG-1 0.467
npp-9 Protein NPP-9 0.463
mat-3 Protein MAT-3 0.453
cmd-1 Protein CMD-1 0.453
lin-13 Protein LIN-13 0.450
adr-1 Protein ADR-1 0.446
deb-1 Protein DEB-1 0.429
mig-2 Protein MIG-2 0.425
insc-1 Protein INSC-1 0.424
F33H2.3 Protein F33H2.3 0.421
F39G3.5 Protein F39G3.5 0.420
lin-25 Protein LIN-25 0.413
spc-1 Protein SPC-1 0.412
ubr-1 Protein UBR-1 0.411
par-5 Protein PAR-5 0.403
rpl-2 Protein RPL-2 0.398
hsp-12.2 Protein HSP-12.2 0.396
gsp-1 Protein GSP-1 0.392
che-13 Protein CHE-13 0.387
tct-1 Protein TCT-1 0.386
cls-2 Protein CLS-2 0.386
pch-2 Protein PCH-2 0.386
hlh-2 Protein HLH-2 0.385
rpa-1 Protein RPA-1 0.384
sma-6 Protein SMA-6 0.381
unc-16 Protein UNC-16 0.377
let-756 Protein LET-756 0.375
ten-1 Protein TEN-1 0.366
hlh-1 Protein HLH-1 0.363
ketn-1 Protein KETN-1 0.352
lec-1 Protein LEC-1 0.350
slo-1 Protein SLO-1 0.349
rpl-24.1 Protein RPL-24.1 0.345
ess-2 Protein ESS-2 0.344
mig-5 Protein MIG-5 0.341
dyc-1 Protein DYC-1 0.340
dnj-12 Protein DNJ-12 0.340
sas-6 Protein SAS-6 0.338
inx-12 Protein INX-12 0.333
rps-6 Protein RPS-6 0.333
CELE_C24H12.5 Protein C24H12.5 0.333
crt-1 Protein CRT-1 0.333
pfd-1 Protein PFD-1 0.331
ced-3 Protein CED-3 0.329
syg-1 Protein SYG-1 0.328
rps-7 Protein RPS-7 0.325
spd-5 Protein SPD-5 0.324
fem-3 Protein FEM-3 0.323
pbs-3 Protein PBS-3 0.323
ajm-1 Protein AJM-1 0.322
gei-4 Protein GEI-4 0.322
T04C9.1 Protein T04C9.1 0.317
cgh-1 Protein CGH-1 0.310
R11A8.7 Protein R11A8.7 0.308
his-1 Protein HIS-1 0.307
twk-18 Protein TWK-18 0.306
rpt-5 Protein RPT-5 0.304
vha-8 Protein VHA-8 0.304
mlc-3 Protein MLC-3 0.300
acs-4 Protein ACS-4 0.298
egl-18 Protein EGL-18 0.295
elt-6 Protein ELT-6 0.295
pat-4 Protein PAT-4 0.293
R08D7.2 Protein R08D7.2 0.287
hsr-9 Protein HSR-9 0.286
pat-12 Protein PAT-12 0.286
csq-1 Protein CSQ-1 0.285
rpl-5 Protein RPL-5 0.285
unc-45 Protein UNC-45 0.285
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Danio rerio
Name Description Probability Func Analog Organism
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.959
ttna titin a 0.868
unc45b unc-45 homolog B (C. elegans) 0.861
ptch2 patched 2 0.854
neb nebulin 0.847
shha sonic hedgehog a 0.845
dag1 dystroglycan 1 0.844
lamc1 laminin, gamma 1 0.811
sass6 spindle assembly 6 homolog (C. elegans) 0.776
pdlim7 PDZ and LIM domain 7 0.770
pak1 p21/Cdc42/Rac1-activated kinase 1 0.745
efnb2a ephrin B2a 0.734
gpr126 G protein-coupled receptor 126 0.719
gli1 GLI-Kruppel family member 1 0.711
lama1 laminin, alpha 1 0.702
lamb1a laminin, beta 1a 0.636
apc adenomatosis polyposis coli 0.595
tnni2a.4 troponin I, skeletal, fast 2a.4 0.583
myod1 myogenic differentiation 1 0.568
flncb filamin C, gamma b (actin binding protein 280) 0.540
ilk integrin linked kinase 0.525
prkci protein kinase C, iota 0.506
cmyb transcription factor cmyb 0.501
snrpc small nuclear ribonucleoprotein polypeptide C 0.487
tnnc1b troponin C type 1b (slow) 0.471
hsp90a.1 heat shock protein 90-alpha 1 0.452
rpl14 ribosomal protein L14 0.448
mfn2 mitofusin 2 0.448
lama2 laminin, alpha 2 0.423
rps5 ribosomal protein S5 0.415
csad cysteine sulfinic acid decarboxylase 0.415
smyd1b SET and MYND domain containing 1b 0.403
desma desmin a 0.396
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.391
kif17 kinesin family member 17 0.385
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.366
rps29 ribosomal protein S29 0.365
zgc:66286 zgc:66286 0.365
perp PERP, TP53 apoptosis effector 0.361
hmgb2b high-mobility group box 2b 0.350
spry4 sprouty (Drosophila) homolog 4 0.344
fbl fibrillarin 0.328
robo2 roundabout homolog 2 0.326
fn1 fibronectin 1 0.324
pxn paxillin 0.314
rps11 ribosomal protein S11 0.309
nrp1a neuropilin 1a 0.306
kif23 kinesin family member 23 0.304
tnni1b troponin I, skeletal, slow b 0.300
bmp4 bone morphogenetic protein 4 0.299
ncor1 nuclear receptor co-repressor 1 0.298
lama5 laminin, alpha 5 0.295
notum3 notum 3 0.292
tpm3 tropomyosin 3 0.291
rpsa ribosomal protein SA 0.288
foxj1b forkhead box J1b 0.281
pdlim5 PDZ and LIM domain 5 0.279
ndrg1 N-myc downstream regulated gene 1 0.278
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.273
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.272
mmp2 matrix metalloproteinase 2 0.268
lamb2 laminin, beta 2 (laminin S) 0.263
arpc5b actin related protein 2/3 complex, subunit 5B 0.261
s100a10b S100 calcium binding protein A10b 0.260
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.259
rps18 ribosomal protein S18 0.257
cnn2 calponin 2 0.253
eif3g eukaryotic translation initiation factor 3, subunit G 0.251
tnni1al troponin I, skeletal, slow like 0.248
vhl von Hippel-Lindau tumor suppressor 0.245
cdh23 cadherin-like 23 0.245
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.244
epb41l5 erythrocyte membrane protein band 4.1 like 5 0.239
xirp1 xin actin-binding repeat containing 1 0.231
mybpc3 myosin binding protein C, cardiac 0.229
smad9 MAD homolog 9 (Drosophila) 0.228
cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.228
ncapg non-SMC condensin I complex, subunit G 0.227
actn2 actinin, alpha 2 0.224
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.222
wu:fl55e11 wu:fl55e11 0.222
yap1 Yes-associated protein 1 0.222
stil TAL1 (SCL) interrupting locus 0.221
tnnt3b troponin T3b, skeletal, fast 0.221
myog myogenin 0.219
rps3a ribosomal protein S3A 0.219
si:dkeyp-84f11.5 si:dkeyp-84f11.5 0.218
si:ch211-212m21.5 si:ch211-212m21.5 0.218
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.218
rap1b RAS related protein 1b 0.216
cdc42 cell division cycle 42 0.216
rpl15 ribosomal protein L15 0.213
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.212
rpl13 ribosomal protein L13 0.210
dld deltaD 0.208
hoxa3a homeo box A3a 0.204
sema3aa semaphorin 3aa 0.204
hspg2 heparan sulfate proteoglycan 2 0.203
prickle1a prickle-like 1 (Drosophila) a 0.203
zbtb4 zinc finger and BTB domain containing 4 0.201
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tpm3 tropomyosin 3, gamma 0.852
Arpc1b actin related protein 2/3 complex, subunit 1B 0.843
Myh9 myosin, heavy chain 9, non-muscle 0.840
Efhd2 EF-hand domain family, member D2 0.705
Wdr1 WD repeat domain 1 0.660
Actn4 actinin alpha 4 0.633
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.623
Tagln transgelin 0.619
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.606
Acta2 smooth muscle alpha-actin 0.548
Cttn cortactin 0.524
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.521
Arpc2 actin related protein 2/3 complex, subunit 2 0.501
Arf6 ADP-ribosylation factor 6 0.477
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.472
Tpm2 tropomyosin 2, beta 0.468
Pfn1 profilin 1 0.457
Stk10 serine/threonine kinase 10 0.444
Nlgn2 neuroligin 2 0.421
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.407
Sirpa signal-regulatory protein alpha 0.407
Ckm creatine kinase, muscle 0.394
Iqgap1 IQ motif containing GTPase activating protein 1 0.393
Cd37 CD37 molecule 0.387
Mapk3 mitogen activated protein kinase 3 0.381
Lmna lamin A 0.380
Flna filamin A, alpha 0.373
Tagln2 transgelin 2 0.372
Anxa2 annexin A2 0.370
Ptbp1 polypyrimidine tract binding protein 1 0.347
Cand1 cullin-associated and neddylation-dissociated 1 0.337
Actn1 actinin, alpha 1 0.334
Cnbp CCHC-type zinc finger, nucleic acid binding protein 0.332
Mapk1 mitogen activated protein kinase 1 0.330
Dstn destrin 0.327
Dlg4 discs, large homolog 4 (Drosophila) 0.326
Actc1 actin, alpha, cardiac muscle 1 0.325
Mobkl2a MOB1, Mps One Binder kinase activator-like 2A (yeast) 0.303
Dlg1 discs, large homolog 1 (Drosophila) 0.300
Tubb5 tubulin, beta 5 0.300
Vasp vasodilator-stimulated phosphoprotein 0.299
Cugbp2 CUG triplet repeat, RNA binding protein 2 0.293
Coro1a coronin, actin binding protein 1A 0.281
Csrp1 cysteine and glycine-rich protein 1 0.279
Hck hemopoietic cell kinase 0.276
S100a10 S100 calcium binding protein A10 0.275
Uba1 ubiquitin-like modifier activating enzyme 1 0.267
Actb actin, beta 0.266
Cryab crystallin, alpha B 0.264
Tmsb10 thymosin, beta 10 0.263
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.262
Ptprc protein tyrosine phosphatase, receptor type, C 0.261
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.257
Stip1 stress-induced phosphoprotein 1 0.254
Tpm1 tropomyosin 1, alpha 0.248
Tgoln1 trans-golgi network protein 0.246
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.244
Trim29 tripartite motif-containing 29 0.242
Lcp2 lymphocyte cytosolic protein 2 0.240
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.239
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.236
Exoc5 exocyst complex component 5 0.230
Laptm5 lysosomal protein transmembrane 5 0.229
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.223
Emp1 epithelial membrane protein 1 0.220
Gmfg glia maturation factor, gamma 0.219
Arf3 ADP-ribosylation factor 3 0.216
Pex5l peroxisomal biogenesis factor 5-like 0.214
Cct2 chaperonin containing TCP1, subunit 2 (beta) 0.213
Ncf4 neutrophil cytosolic factor 4 0.212
Rhoa ras homolog gene family, member A 0.211
Dpysl3 dihydropyrimidinase-like 3 0.209
Ccl3 chemokine (C-C motif) ligand 3 0.204
Robo2 roundabout homolog 2 (Drosophila) 0.204
Rplp0 ribosomal protein, large, P0 0.202
Arpc3 actin related protein 2/3 complex, subunit 3 0.198
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.196
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.193
Cd82 Cd82 molecule 0.193
Inpp5d inositol polyphosphate-5-phosphatase D 0.191
Ptma prothymosin alpha 0.188
LOC685045 similar to Protein C6orf115 0.187
Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.185
Notch3 Notch homolog 3 (Drosophila) 0.184
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.183
Eef2 eukaryotic translation elongation factor 2 0.181
Tgfb1 transforming growth factor, beta 1 0.181
Ube2c ubiquitin-conjugating enzyme E2C 0.177
Des desmin 0.176
Map2 microtubule-associated protein 2 0.176
Map1a microtubule-associated protein 1A 0.175
Ripk3 receptor-interacting serine-threonine kinase 3 0.174
Prkcg protein kinase C, gamma 0.173
Sdc1 syndecan 1 0.168
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.166
Gja6 gap junction protein, alpha 6 0.163
Vav1 vav 1 guanine nucleotide exchange factor 0.159
Actn2 actinin alpha 2 0.159
Ifngr1 interferon gamma receptor 1 0.158
Cfp complement factor properdin 0.158
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
DAM1 Dam1p 1.000
RVS167 Rvs167p 0.999
TID3 Tid3p 0.994
ARP2 Arp2p 0.994
ASK1 Ask1p 0.994
CRN1 Crn1p 0.993
NUF2 Nuf2p 0.984
BIM1 Bim1p 0.983
MPS1 Mps1p 0.981
SPC34 Spc34p 0.979
SPC24 Spc24p 0.979
AKL1 Akl1p 0.971
ACT1 Act1p 0.968
SPC97 Spc97p 0.968
RAD23 Rad23p 0.957
CMD1 Cmd1p 0.955
CLB3 Clb3p 0.951
MYO5 Myo5p 0.949
CDC25 Cdc25p 0.949
CIN8 Cin8p 0.944
SPA2 Spa2p 0.939
END3 End3p 0.937
BUD6 Bud6p 0.936
GIN4 Gin4p 0.925
LAS17 Las17p 0.923
ARC35 Arc35p 0.916
SSK2 Ssk2p 0.915
SPC29 Spc29p 0.910
ARC15 Arc15p 0.892
HSL1 Hsl1p 0.878
KEL1 Kel1p 0.877
YPK1 Ypk1p 0.875
SPC110 Spc110p 0.874
CBF2 Cbf2p 0.870
PAC10 Pac10p 0.867
RHO1 Rho1p 0.866
ARC40 Arc40p 0.864
RPS8A Rps8ap 0.861
SPC19 Spc19p 0.858
DAD4 Dad4p 0.855
ARP3 Arp3p 0.854
DUO1 Duo1p 0.846
DAD2 Dad2p 0.838
SAC6 Sac6p 0.835
SLA2 Sla2p 0.835
CDC24 Cdc24p 0.825
KAR9 Kar9p 0.825
ARC18 Arc18p 0.824
DBF2 Dbf2p 0.822
BBP1 Bbp1p 0.820
DYN1 Dyn1p 0.816
SYP1 Syp1p 0.814
TSC11 Tsc11p 0.811
BMH2 Bmh2p 0.809
BBC1 Bbc1p 0.805
SRV2 Srv2p 0.801
MOB1 Mob1p 0.799
NIP100 Nip100p 0.798
CDC55 Cdc55p 0.795
DAD1 Dad1p 0.792
SPC42 Spc42p 0.780
SLM2 Slm2p 0.776
CAP1 Cap1p 0.773
CDC28 Cdc28p 0.771
SPC105 Spc105p 0.765
CDC12 Cdc12p 0.760
RPT3 Rpt3p 0.742
SHS1 Shs1p 0.738
RFC5 Rfc5p 0.724
ABP1 Abp1p 0.718
FUN12 Fun12p 0.708
BEM2 Bem2p 0.708
NDC1 Ndc1p 0.706
SGO1 Sgo1p 0.703
CNM67 Cnm67p 0.697
GIC2 Gic2p 0.694
RPL17A Rpl17ap 0.691
NBP2 Nbp2p 0.667
SPC98 Spc98p 0.666
SMI1 Smi1p 0.663
PEX13 Pex13p 0.659
ZDS1 Zds1p 0.659
BEM4 Bem4p 0.657
TPM1 Tpm1p 0.652
RPL17B Rpl17bp 0.647
CDC5 Cdc5p 0.647
DSN1 Dsn1p 0.642
CDC20 Cdc20p 0.639
PHO85 Pho85p 0.627
AIM3 Aim3p 0.626
UBA4 Uba4p 0.625
RPS1A Rps1ap 0.620
RPL16A Rpl16ap 0.612
SWE1 Swe1p 0.610
BIK1 Bik1p 0.609
EDE1 Ede1p 0.606
MYO2 Myo2p 0.604
CLA4 Cla4p 0.598
RPL4B Rpl4bp 0.596
HTA2 Hta2p 0.594