IMP
Process View
The network for 'regulation of b cell receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of b cell receptor signaling pathway
Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | 0.561 | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.543 | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.520 | |
| FHL2 | four and a half LIM domains 2 | 0.491 | |
| TFF1 | trefoil factor 1 | 0.398 | |
| NCF1 | neutrophil cytosolic factor 1 | 0.315 | |
| NCK2 | NCK adaptor protein 2 | 0.254 | |
| LPXN | leupaxin | 0.227 | |
| SYK | spleen tyrosine kinase | 0.200 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.182 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.145 | |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.143 | |
| CD22 | CD22 molecule | 0.135 | |
| GRB2 | growth factor receptor-bound protein 2 | 0.102 | |
| VCL | vinculin | 0.100 | |
| CD247 | CD247 molecule | 0.085 | |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.078 | |
| CD33 | CD33 molecule | 0.070 | |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.069 | |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.068 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.067 | |
| PECAM1 | platelet/endothelial cell adhesion molecule | 0.063 | |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.062 | |
| CYBA | cytochrome b-245, alpha polypeptide | 0.060 | |
| HOXA1 | homeobox A1 | 0.059 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.059 | |
| SH2D2A | SH2 domain containing 2A | 0.057 | |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.056 | |
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.051 | |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.050 | |
| PRKCD | protein kinase C, delta | 0.047 | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.047 | |
| MEST | mesoderm specific transcript homolog (mouse) | 0.046 | |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.044 | |
| LAT | linker for activation of T cells | 0.043 | |
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.043 | |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.042 | |
| PRKCQ | protein kinase C, theta | 0.040 | |
| BBS10 | Bardet-Biedl syndrome 10 | 0.039 | |
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.038 | |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.035 | |
| HDAC6 | histone deacetylase 6 | 0.035 | |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.034 | |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.033 | |
| EPOR | erythropoietin receptor | 0.029 | |
| ZNF426 | zinc finger protein 426 | 0.029 | |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.029 | |
| TRIM9 | tripartite motif containing 9 | 0.028 | |
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.027 | |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.023 | |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 | 0.023 | |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.022 | |
| SH2D1A | SH2 domain containing 1A | 0.022 | |
| PHF21A | PHD finger protein 21A | 0.022 | |
| ILK | integrin-linked kinase | 0.021 | |
| SIGLEC10 | sialic acid binding Ig-like lectin 10 | 0.020 | |
| DPEP2 | dipeptidase 2 | 0.020 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.020 | |
| LRMP | lymphoid-restricted membrane protein | 0.020 | |
| SH3BP2 | SH3-domain binding protein 2 | 0.019 | |
| IL4R | interleukin 4 receptor | 0.019 | |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.018 | |
| CTTN | cortactin | 0.017 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.016 | |
| ROS1 | c-ros oncogene 1 , receptor tyrosine kinase | 0.016 | |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.016 | |
| AHNAK | AHNAK nucleoprotein | 0.015 | |
| CD300LF | CD300 molecule-like family member f | 0.015 | |
| ZNF331 | zinc finger protein 331 | 0.015 | |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.014 | |
| AIF1 | allograft inflammatory factor 1 | 0.014 | |
| WDYHV1 | WDYHV motif containing 1 | 0.014 | |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.014 | |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.014 | |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.013 | |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.013 | |
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.013 | |
| PPP1R14A | protein phosphatase 1, regulatory (inhibitor) subunit 14A | 0.013 | |
| GAB1 | GRB2-associated binding protein 1 | 0.013 | |
| CD2 | CD2 molecule | 0.012 | |
| FAM65B | family with sequence similarity 65, member B | 0.012 | |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.012 | |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 | 0.012 | |
| RALBP1 | ralA binding protein 1 | 0.012 | |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 | 0.012 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.012 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.011 | |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.011 | |
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.011 | |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.011 | |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.011 | |
| ITGA7 | integrin, alpha 7 | 0.011 | |
| CD72 | CD72 molecule | 0.011 | |
| PRKCA | protein kinase C, alpha | 0.011 | |
| SIRPA | signal-regulatory protein alpha | 0.011 | |
| TLN1 | talin 1 | 0.011 | |
| RNF5 | ring finger protein 5 | 0.010 | |
| FHOD1 | formin homology 2 domain containing 1 | 0.010 | |
| ADAMTSL4 | ADAMTS-like 4 | 0.010 | |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fyn | Fyn proto-oncogene | 0.999 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.671 | |
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.464 | |
| Prkce | protein kinase C, epsilon | 0.221 | |
| Cd22 | CD22 antigen | 0.212 | |
| Ldb3 | LIM domain binding 3 | 0.194 | |
| Cbl | Casitas B-lineage lymphoma | 0.184 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.157 | |
| Vav1 | vav 1 oncogene | 0.155 | |
| Grb2 | growth factor receptor bound protein 2 | 0.119 | |
| Wipf1 | WAS/WASL interacting protein family, member 1 | 0.105 | |
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.076 | |
| Was | Wiskott-Aldrich syndrome homolog (human) | 0.074 | |
| Src | Rous sarcoma oncogene | 0.060 | |
| Cd19 | CD19 antigen | 0.058 | |
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.048 | |
| Dok1 | docking protein 1 | 0.045 | |
| Cd247 | CD247 antigen | 0.044 | |
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.041 | |
| Ptpre | protein tyrosine phosphatase, receptor type, E | 0.037 | |
| Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.035 | |
| Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.030 | |
| Igh | immunoglobulin heavy chain complex | 0.026 | |
| Lat | linker for activation of T cells | 0.025 | |
| Il2rg | interleukin 2 receptor, gamma chain | 0.025 | |
| Homer1 | homer homolog 1 (Drosophila) | 0.022 | |
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.021 | |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.020 | |
| Plcg1 | phospholipase C, gamma 1 | 0.020 | |
| Hcls1 | hematopoietic cell specific Lyn substrate 1 | 0.019 | |
| Blnk | B-cell linker | 0.019 | |
| Cd72 | CD72 antigen | 0.017 | |
| Tcra | T-cell receptor alpha chain | 0.016 | |
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.016 | |
| Hck | hemopoietic cell kinase | 0.015 | |
| Lck | lymphocyte protein tyrosine kinase | 0.015 | |
| Prkcb | protein kinase C, beta | 0.013 | |
| Prkcc | protein kinase C, gamma | 0.013 | |
| Cd4 | CD4 antigen | 0.013 | |
| Pag1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.013 | |
| Cd40 | CD40 antigen | 0.013 | |
| Sykb | spleen tyrosine kinase | 0.013 | |
| Tnf | tumor necrosis factor | 0.013 | |
| Hcst | hematopoietic cell signal transducer | 0.012 | |
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.012 | |
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.012 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.012 | |
| Shc1 | src homology 2 domain-containing transforming protein C1 | 0.012 | |
| Cd37 | CD37 antigen | 0.011 | |
| Flt1 | FMS-like tyrosine kinase 1 | 0.011 |