IMP
Process View
The network for 'negative regulation of neutrophil chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of neutrophil chemotaxis
Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.890 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.489 | |
| DCN | decorin | 0.391 | |
| ATN1 | atrophin 1 | 0.266 | |
| COL14A1 | collagen, type XIV, alpha 1 | 0.150 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.146 | |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.110 | |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.062 | |
| COL1A2 | collagen, type I, alpha 2 | 0.056 | |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.053 | |
| SFRP4 | secreted frizzled-related protein 4 | 0.049 | |
| POSTN | periostin, osteoblast specific factor | 0.043 | |
| COL3A1 | collagen, type III, alpha 1 | 0.041 | |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.038 | |
| MFAP4 | microfibrillar-associated protein 4 | 0.035 | |
| BAIAP2 | BAI1-associated protein 2 | 0.032 | |
| LAMA4 | laminin, alpha 4 | 0.030 | |
| MGP | matrix Gla protein | 0.028 | |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.025 | |
| VCAN | versican | 0.024 | |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.023 | |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.022 | |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.021 | |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.020 | |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.020 | |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.020 | |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.019 | |
| SLIT2 | slit homolog 2 (Drosophila) | 0.019 | |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.019 | |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.019 | |
| MXRA5 | matrix-remodelling associated 5 | 0.019 | |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.018 | |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.018 | |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.017 | |
| DPT | dermatopontin | 0.017 | |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.017 | |
| BNC2 | basonuclin 2 | 0.017 | |
| CHRDL1 | chordin-like 1 | 0.017 | |
| VGLL3 | vestigial like 3 (Drosophila) | 0.016 | |
| SRPX | sushi-repeat containing protein, X-linked | 0.015 | |
| COL6A3 | collagen, type VI, alpha 3 | 0.015 | |
| AEBP1 | AE binding protein 1 | 0.015 | |
| LDB2 | LIM domain binding 2 | 0.015 | |
| FBLN5 | fibulin 5 | 0.015 | |
| SPARCL1 | SPARC-like 1 (hevin) | 0.015 | |
| CCDC80 | coiled-coil domain containing 80 | 0.015 | |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.015 | |
| FBLN2 | fibulin 2 | 0.014 | |
| OMD | osteomodulin | 0.014 | |
| JAM2 | junctional adhesion molecule 2 | 0.014 | |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.014 | |
| GIGYF1 | GRB10 interacting GYF protein 1 | 0.013 | |
| SFRP2 | secreted frizzled-related protein 2 | 0.013 | |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.013 | |
| LAMA2 | laminin, alpha 2 | 0.013 | |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.012 | |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.012 | |
| C7 | complement component 7 | 0.012 | |
| FBN1 | fibrillin 1 | 0.012 | |
| FRZB | frizzled-related protein | 0.012 | |
| SFRP1 | secreted frizzled-related protein 1 | 0.012 | |
| FMOD | fibromodulin | 0.011 | |
| MEGF11 | multiple EGF-like-domains 11 | 0.011 | |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.011 | |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.011 | |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.011 | |
| TGFB3 | transforming growth factor, beta 3 | 0.011 | |
| OLFML1 | olfactomedin-like 1 | 0.010 |
Loading network...
Danio rerio
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| cxcl12a | chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) | 0.860 | |
| kdrl | kinase insert domain receptor like | 0.579 | |
| cxcl12b | chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) | 0.467 | |
| cxcr4a | chemokine (C-X-C motif) receptor 4a | 0.331 | |
| cxcr4b | chemokine (C-X-C motif), receptor 4b | 0.216 | |
| btg2 | B-cell translocation gene 2 | 0.134 | |
| spi1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.125 | |
| krml2.2 | Kreisler (mouse) maf-related leucine zipper homolog 2.2 | 0.099 | |
| dlc | deltaC | 0.097 | |
| etv2 | ets variant gene 2 | 0.084 | |
| dld | deltaD | 0.075 | |
| grhl2b | grainyhead-like 2b (Drosophila) | 0.069 | |
| mafba | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) | 0.068 | |
| dhrs3a | dehydrogenase/reductase (SDR family) member 3a | 0.063 | |
| fbn2b | fibrillin 2b | 0.062 | |
| hhip | hedgehog interacting protein | 0.057 | |
| epha4a | eph receptor A4a | 0.054 | |
| crip2 | cysteine-rich protein 2 | 0.048 | |
| lmo4a | LIM domain only 4a | 0.047 | |
| myod1 | myogenic differentiation 1 | 0.042 | |
| dact2 | dapper homolog 2, antagonist of beta-catenin (xenopus) | 0.041 | |
| aplnrb | apelin receptor b | 0.040 | |
| grna | granulin a | 0.040 | |
| pea3 | ETS-domain transcription factor pea3 | 0.038 | |
| ptprc | protein tyrosine phosphatase, receptor type, C | 0.038 | |
| sfrp1a | secreted frizzled-related protein 1a | 0.037 | |
| bon | bonnie and clyde | 0.036 | |
| si:dkeyp-7c9.1 | si:dkeyp-7c9.1 | 0.036 | |
| sulf1 | sulfatase 1 | 0.033 | |
| lef1 | lymphocyte enhancer binding factor 1 | 0.031 | |
| lmo2 | LIM domain only 2 (rhombotin-like 1) | 0.030 | |
| nkx2.5 | NK2 transcription factor related 5 | 0.030 | |
| pdzrn3 | PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3 | 0.029 | |
| aplnra | apelin receptor a | 0.029 | |
| her6 | hairy-related 6 | 0.028 | |
| sox10 | SRY-box containing gene 10 | 0.027 | |
| mych | myelocytomatosis oncogene homolog | 0.026 | |
| apoeb | apolipoprotein Eb | 0.026 | |
| meis1 | myeloid ecotropic viral integration 1 | 0.026 | |
| hlx1 | H2.0-like homeo box 1 (Drosophila) | 0.026 | |
| vsg1 | vessel-specific 1 | 0.025 | |
| foxc1b | forkhead box C1b | 0.025 | |
| si:dkey-261h17.1 | si:dkey-261h17.1 | 0.024 | |
| gmfg | glia maturation factor, gamma | 0.024 | |
| bmper | BMP binding endothelial regulator | 0.021 | |
| cdh5 | cadherin 5 | 0.021 | |
| epha7 | eph receptor A7 | 0.020 | |
| hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.020 | |
| pdgfaa | platelet-derived growth factor alpha a | 0.020 | |
| lrrc33 | leucine rich repeat containing 33 | 0.020 | |
| tal1 | T-cell acute lymphocytic leukemia 1 | 0.020 | |
| hspa12b | heat shock protein 12B | 0.019 | |
| clic4 | chloride intracellular channel 4 | 0.019 | |
| spry1 | sprouty homolog 1 (Drosophila) | 0.019 | |
| prox1 | prospero-related homeobox gene 1 | 0.018 | |
| nrarpa | notch-regulated ankyrin repeat protein a | 0.018 | |
| kal1b | Kallmann syndrome 1b sequence | 0.018 | |
| cdh1 | cadherin 1, epithelial | 0.017 | |
| ntla | no tail a | 0.017 | |
| her1 | hairy-related 1 | 0.017 | |
| crh | corticotropin releasing hormone | 0.017 | |
| mmp2 | matrix metalloproteinase 2 | 0.017 | |
| id2a | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a | 0.017 | |
| cadm1a | cell adhesion molecule 1a | 0.016 | |
| lfng | lunatic fringe homolog | 0.016 | |
| coro1a | coronin, actin binding protein, 1A | 0.016 | |
| yrk | Yes-related kinase | 0.016 | |
| acvrl1 | activin A receptor type II-like 1 | 0.016 | |
| gsc | goosecoid | 0.016 | |
| lhx9 | LIM homeobox 9 | 0.016 | |
| ptmaa | prothymosin, alpha a | 0.016 | |
| aldh1a2 | aldehyde dehydrogenase 1 family, member A2 | 0.015 | |
| rhogb | ras homolog gene family, member Gb | 0.015 | |
| ogt.1 | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1 | 0.015 | |
| flncb | filamin C, gamma b (actin binding protein 280) | 0.015 | |
| kctd12.2 | potassium channel tetramerisation domain containing 12.2 | 0.015 | |
| spry4 | sprouty (Drosophila) homolog 4 | 0.014 | |
| hmx2 | H6 family homeobox 2 | 0.014 | |
| blf | bloody fingers | 0.014 | |
| med12 | mediator of RNA polymerase II transcription, subunit 12 homolog | 0.013 | |
| pcdh18a | protocadherin 18a | 0.013 | |
| kal1a | Kallmann syndrome 1a sequence | 0.013 | |
| ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.013 | |
| lyz | lysozyme | 0.013 | |
| dusp5 | dual specificity phosphatase 5 | 0.013 | |
| cdkn1c | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.012 | |
| mcm5 | MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) | 0.012 | |
| efnb2a | ephrin B2a | 0.012 | |
| gdf6a | growth differentiation factor 6a | 0.012 | |
| pmch | pro-melanin concentrating hormone | 0.012 | |
| ptena | phosphatase and tensin homolog A | 0.011 | |
| pak2a | p21 (CDKN1A)-activated kinase 2a | 0.011 | |
| maf | v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog | 0.011 | |
| csrp1a | cysteine and glycine-rich protein 1a | 0.010 | |
| gata1a | GATA binding protein 1a | 0.010 | |
| lrrc6 | leucine rich repeat containing 6 | 0.010 | |
| mmp9 | matrix metalloproteinase 9 | 0.010 |